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1. 发明专利

JP2010273598A Method for manufacturing tyrosinase activity inhibitor 有权
标题翻译：制备酪氨酸酶活性抑制剂的方法
公开(公告)号：JP2010273598A
公开(公告)日：2010-12-09
申请号：JP2009128842
申请日：2009-05-28
申请人： Kanazawa Inst Of Technology , 学校法人金沢工業大学
发明人： OZEKI KENJI
IPC分类号： C12P19/14 , A23L5/41 , A61K8/97 , A61K8/99 , A61Q19/02 , C12N9/99
CPC分类号： Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a tyrosinase activity inhibitor and a melaninogenesis suppressing agent by using hemicellulose content materials such as rice bran and wheat bran.
SOLUTION: Hemicellulose high content plants or its sections are treated by using enzyme or β-glucosidase or xylanase high production aspergillus oryzae having hemicellulose decomposition activity, and the tyrosinase activity inhibitor is manufactured, and used as a melanogenesis inhibitor, a cosmetic for bleaching, and a food browning inhibitor.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：通过使用半米纤维素含量的材料如米糠和麦麸来提供酪氨酸酶活性抑制剂和黑素生成抑制剂。解决方案：通过使用具有半纤维素分解活性的酶或β-葡糖苷酶或木聚糖酶高产的米曲霉来处理半纤维素高含量植物或其切片，并且制造酪氨酸酶活性抑制剂，并用作黑素生成抑制剂，用于漂白剂和食物褐变抑制剂。版权所有（C）2011，JPO＆INPIT

2. 发明专利

JP2011092185A Method for promoting decomposition of acrylamide 审中-公开
标题翻译：促进丙烯酰胺分解的方法
公开(公告)号：JP2011092185A
公开(公告)日：2011-05-12
申请号：JP2010187380
申请日：2010-08-24
申请人： Kanazawa Inst Of Technology , 学校法人金沢工業大学
发明人： OZEKI KENJI , YAMAMOTO HIROKI , FUJIMOTO NAOKO , WAKAIZUMI MASAKATSU
IPC分类号： C12N1/14 , C12N1/00 , C12N11/00
摘要： PROBLEM TO BE SOLVED: To provide a method for producing filamentous fungus induced with acrylamide-decomposing function and the filamentous fungus obtained by the method. SOLUTION: This method for producing the filamentous fungus induced with the acrylamide-decomposing function is provided by culturing the filamentous fungus in an acrylamide-containing medium under the condition of pH 7.5 to 11.0. The method for producing immobilized filamentous fungus induced with the acrylamide-decomposing function is provided by comprising the following processes: (a) performing pre-incubation of a carrier with a nutrition source-containing medium, (b) culturing the filamentous fungus in a medium containing the carrier, and then (c) culturing the immobilized filamentous fungus on the carrier under the condition of pH 7.5 to 11.0 in the acrylamide-containing medium. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供用丙烯酰胺分解功能诱导的丝状真菌的方法和通过该方法获得的丝状真菌的方法。解决方案：通过在pH 7.5〜11.0的条件下，在含丙烯酰胺的培养基中培养丝状真菌来提供用丙烯酰胺分解功能诱导的丝状真菌的制造方法。通过包括以下方法提供用丙烯酰胺分解功能诱导的固定化丝状真菌的方法：（a）使载体与含营养源的培养基进行预温育，（b）在培养基中培养丝状真菌含有载体，然后（c）在含有丙烯酰胺的培养基中，在pH 7.5〜11.0的条件下，在载体上培养固定化的丝状真菌。版权所有（C）2011，JPO＆INPIT

3. 发明专利

JP2011036241A Method for preparation of angiotensin-converting enzyme inhibitor peptide 审中-公开
标题翻译：抗生素转化酶抑制剂肽的制备方法
公开(公告)号：JP2011036241A
公开(公告)日：2011-02-24
申请号：JP2010151187
申请日：2010-07-01
申请人： Chikuno Shokuhin Kogyo Kk , Kanazawa Inst Of Technology , 学校法人金沢工業大学 , 築野食品工業株式会社
发明人： OZEKI KENJI , CHIKUNO TAKUO , YAMANAKA TAKASHI
IPC分类号： C12P21/06 , A23K1/00 , A23L1/305 , A61K38/00 , A61P9/12 , A61P43/00 , C12N9/99
CPC分类号： Y02P60/877
摘要： PROBLEM TO BE SOLVED: To provide a method for preparation of an ACE inhibitor by using a protein obtained from rice bran, especially from low-degeneration defatted rice bran. SOLUTION: The method comprises the step of treating a protein obtained from extraction of the low-degeneration defatted rice bran, with a first protease, and then treating with a second protease. The low-degeneration defatted rice bran can be obtained by removing solvent from the residue of extraction of rice bran with at least a kind of extracted solvent selected from acetone, hexane and ethanol. The protein can be extracted from the low-degeneration defatted rice bran by using alkaline water or acidic water. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种通过使用从米糠获得的蛋白质，特别是低变质脱脂米糠制备ACE抑制剂的方法。解决方案：该方法包括用第一种蛋白酶处理从低变性脱脂米糠的提取获得的蛋白质，然后用第二种蛋白酶处理的步骤。通过用至少一种选自丙酮，己烷和乙醇的提取溶剂从米糠提取残留物中除去溶剂，可以获得低变质脱脂米糠。蛋白质可以通过使用碱性水或酸性水从低退化脱脂米糠中提取。版权所有（C）2011，JPO＆INPIT

4. 发明专利

JP2013172711A Antioxidant composition, composition inhibiting activity of disaccharide hydrolase, composition for intestinal regulation, diet composition, food and drink, and method of selectively producing arabinose 审中-公开
标题翻译：抗氧化剂组合物，不饱和脂肪酸盐的组合物抑制活性，用于内分泌调节的组合物，饮食组合物，食物和饮料以及选择性生产阿拉伯糖的方法
公开(公告)号：JP2013172711A
公开(公告)日：2013-09-05
申请号：JP2013011960
申请日：2013-01-25
申请人： Kanazawa Inst Of Technology , 学校法人金沢工業大学 , Ishikawa Prefecture , 石川県 , Habutaetoufu Co Ltd , 羽二重豆腐株式会社
发明人： OZEKI KENJI , FUJIWARA EIJI , KAWASHIMA MASAO , NAKAMURA SHIZUO , TAKE HARUMI
IPC分类号： A23L1/20 , A23L1/00 , A23L1/30 , A61K36/00 , A61K36/48 , A61P1/12 , A61P3/04 , A61P9/06 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an antioxidant composition having an excellent antioxidant action, a composition inhibiting activity of disaccharide hydrolase, having an excellent action of inhibiting activity of disaccharide hydrolase, a composition for intestinal regulation having an excellent action for intestinal regulation, a diet composition having an excellent diet action, each making use of bean curd lees not effectively used, food and drink, and a method of selectively producing arabinose.SOLUTION: An antioxidant composition includes enzyme-treated bean curd lees prepared by treating bean curd lees with a cell-wall decomposing enzyme. A composition inhibiting activity of disaccharide hydrolase, a composition for intestinal regulation and a diet composition each include fermented enzyme-treated bean curd lees prepared by fermenting the enzyme-treated bean curd lees with yeast, prepared by treating bean curd lees with a cell-wall decomposing enzyme. Food and drink include at least any of the antioxidant composition, the composition inhibiting activity of disaccharide hydrolase, the composition for intestinal regulation and the diet composition. A method of selectively producing arabinose includes treating bean curd lees with a cell-wall decomposing enzyme to prepare the enzyme-treated bean curd lees, and selectively obtaining arabinose made soluble in a liquid constituting the enzyme-treated bean curd lees.
摘要翻译：要解决的问题：提供具有优异的抗氧化作用的抗氧化剂组合物，抑制二糖水解酶活性的二糖水解酶的组合物抑制活性，具有抑制二糖水解酶活性的优异作用，用于肠调节的肠调节组合物，饮食具有优异的饮食动作的组合物，各自使用没有有效使用的豆腐汁，食品和饮料，以及选择性生产阿拉伯糖的方法。溶解剂：抗氧化剂组合物包括通过用豆腐汁处理豆腐汁制备的酶处理的豆腐汁细胞壁分解酶。二糖水解酶的组合物抑制活性，肠调节组合物和饮食组合物各自包括通过用酵母发酵酶处理的豆腐汁制备的发酵酶处理的豆腐汁，其通过用细胞壁处理豆腐汁分解酶。食品和饮料至少包括抗氧化剂组合物，二糖水解酶的组合物抑制活性，肠调节组合物和饮食组成。选择性地生产阿拉伯糖的方法包括用细胞壁分解酶处理豆腐汁以制备酶处理的豆腐汁，并且选择性地获得可溶于构成酶处理豆腐渣的液体中的阿拉伯糖。

5. 发明专利

JP2013158289A Acrylamide-degrading self-cloning aspergillus oryzae 有权
标题翻译：丙烯酰胺降解自蔓延法兰克西ORYZAE
公开(公告)号：JP2013158289A
公开(公告)日：2013-08-19
申请号：JP2012022290
申请日：2012-02-03
申请人： Kanazawa Inst Of Technology , 学校法人金沢工業大学 , Ucc Ueshima Coffee Co Ltd , ユーシーシー上島珈琲株式会社 , Ozeki Corp , 大関株式会社
发明人： OZEKI KENJI , SANO MOTOAKI , IWAI KAZUYA , FUKUNAGA TAIJI , NARITA YUSAKU , TSUBOI HIROKAZU , BOGAKI TAKAYUKI
IPC分类号： C12N1/15 , A23F5/24 , A23L5/20 , C12N15/09
CPC分类号： A23F5/163 , A23F5/204 , A23L2/56 , A23L5/25 , C12N9/80 , C12Y305/01004
摘要： PROBLEM TO BE SOLVED: To provide a self-cloning Aspergillus oryzae expressing an amidase without using induction culture and having high acrylamide degrading activity and a method for reducing acrylamide by using the Aspergillus oryzae.SOLUTION: There are provided a self-cloning Aspergillus oryzae that is transfected in a state that expresses, without induction culturing, a gene encoding a polypeptide having a specific amino acid sequence derived from the Aspergillus oryzae or a gene having a sequence hybridizable under stringent conditions with a nucleic acid molecule comprising a base sequence complementary to a nucleic acid molecule encoding the polypeptide and further encoding a protein having amidase activity; a method for reducing acrylamide comprising a step of treating acrylamide-containing matter with contact with the Aspergillus oryzae; and a method for producing a reduced-acrylamide food or beverage.
摘要翻译：要解决的问题：提供一种自我克隆的米曲霉，其不使用诱导培养并且具有高丙烯酰胺降解活性而表达酰胺酶，以及使用米曲霉还原丙烯酰胺的方法。提供了一种自体克隆米曲霉以表达无诱导培养的状态转染表达编码具有源于米曲霉的特异性氨基酸序列的多肽的基因或具有在严格条件下可与杂交的序列的基因的核酸分子的核酸分子，所述核酸分子包含与编码所述多肽的核酸分子，并进一步编码具有酰胺酶活性的蛋白质; 一种还原丙烯酰胺的方法，包括与米曲霉接触处理含丙烯酰胺的物质的步骤; 和还原丙烯酰胺食品或饮料的制造方法。

6. 发明专利

JP2010183867A Method for degrading acrylamide 审中-公开
标题翻译：降解丙烯酰胺的方法
公开(公告)号：JP2010183867A
公开(公告)日：2010-08-26
申请号：JP2009029836
申请日：2009-02-12
申请人： Kanazawa Inst Of Technology , Sanko Shoji Kk , 三興商事株式会社 , 学校法人金沢工業大学
发明人： OZEKI KENJI , YAMAMOTO HIROKI , FUJIMOTO NAOKO , WAKAIZUMI MASAKATSU
IPC分类号： C12N1/00 , A23L5/20 , C12M1/40 , C12N11/04 , C12R1/69
摘要： PROBLEM TO BE SOLVED: To provide a method for degrading acrylamide with Aspergillus oryzae, and to provide an acrylamide-degrading system.
SOLUTION: The Aspergillus oryzae is A. oryzae KBN1010 strain or A.oryzae No.100 strain. The Aspergillus oryzae is immobilized. The acrylamide in a food is degraded. The acrylamide-degrading system degrades the acrylamide with the strains. Nutrients and oxygen are supplied to the strain to degrade the acrylamide, while preventing the deterioration of the activity.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供一种用米曲霉降解丙烯酰胺的方法，并提供丙烯酰胺降解体系。解决方案：米曲霉是米曲霉KBN1010菌株或A.oryzae No.100菌株。米曲霉被固定化。食品中的丙烯酰胺被降解。丙烯酰胺降解系统使菌株降解丙烯酰胺。将营养物质和氧气供应给菌株以降解丙烯酰胺，同时防止活性的降低。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2008072956A α-GLUCOSIDASE B, α-GLUCOSIDASE B GENE, VECTOR CONTAINING THE α-GLUCOSIDASE B GENE, TRANSFORMANT INCORPORATED WITH THE VECTOR AND METHOD FOR PRODUCING α-GLUCOSIDASE B 审中-公开
标题翻译： α-GLUCOSIDASE B，α-GLUCOSIDASE B基因，含有α-葡糖苷酶B基因的载体，与载体共同转化的转化体和用于产生α-葡萄球菌素B的方法
公开(公告)号：JP2008072956A
公开(公告)日：2008-04-03
申请号：JP2006255936
申请日：2006-09-21
申请人： Kanazawa Inst Of Technology , Mukogawa Gakuin , 学校法人武庫川学院 , 学校法人金沢工業大学
发明人： TAKII YUKIO , OZEKI KENJI , NAGAYOSHI EMI
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/26 , C12R1/69
摘要： PROBLEM TO BE SOLVED: To provide a method for producing α-glucosidase having high transglucosylation activity. SOLUTION: The α-glucosidase B has an amino acid sequence of specific sequence. The α-glucosidase B gene encodes the α-glucosidase B. The α-glucosidase B gene has a base sequence of specific sequence. The vector contains the α-glucosidase B gene. The transformant is incorporated with the vector. The method for producing α-glucosidase comprises culturing the transformant to give the α-glucosidase. The α-glucosidase B is especially preferably obtained as an extracellular enzyme. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：待解决的问题：提供生产具有高转葡糖基活性的α-葡糖苷酶的方法。解决方案：α-葡糖苷酶B具有特定序列的氨基酸序列。 α-葡糖苷酶B基因编码α-葡糖苷酶B.α-葡糖苷酶B基因具有特异性序列的碱基序列。载体含有α-葡糖苷酶B基因。转化体与载体结合。生产α-葡糖苷酶的方法包括培养转化体以得到α-葡糖苷酶。 α-葡糖苷酶B特别优选作为细胞外酶获得。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2012165705A Product obtained by using chaff and brans, and method for producing the same 有权
标题翻译：使用树脂和布料获得的产品及其生产方法
公开(公告)号：JP2012165705A
公开(公告)日：2012-09-06
申请号：JP2011030156
申请日：2011-02-15
申请人： Kanazawa Inst Of Technology , Nisshin Seifun Group Inc , 学校法人金沢工業大学 , 株式会社日清製粉グループ本社
发明人： OZEKI KENJI , SHIRAI YUTAKA , HIRAMOTO SHIGERU , KANEKO AKIHIRO
IPC分类号： A23L1/30 , C12N9/24 , C12N9/42 , C12P19/02
CPC分类号： Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a product with increased production of hemicellulase and/or cellulase, a method for producing the same, and a method for smoothly producing a cellulose- and hemicellulose-derived soluble substances from wheat bran.SOLUTION: There are provided: the product with improved production of hemicellulase and cellulase by inoculating and culturing aspergilli in chaff and brans from which starch is removed; and the method for producing the hemicellulose- and/or cellulose-derived soluble substances by treating the chaff and brans from which starch is removed with an enzyme preparation or substance containing hemicellulase and/or cellulase.
摘要翻译：待解决的问题：为了提供具有增加的半纤维素酶和/或纤维素酶生产的产品，其制备方法以及从麦麸中平滑地生产纤维素和半纤维素衍生的可溶性物质的方法。解决方案：提供：通过在去除淀粉的谷壳和麸中接种和培养曲霉菌来改进半纤维素酶和纤维素酶的生产，以及通过用酶制剂或含有半纤维素酶和/或纤维素酶的物质处理去除淀粉的谷壳和芽孢来生产半纤维素和/或纤维素衍生的可溶性物质的方法。版权所有（C）2012，JPO＆INPIT

9. 发明专利

JP2010035449A Screening of acrylamide-degrading microorganism 审中-公开
标题翻译：丙烯酰胺降解微生物的筛选
公开(公告)号：JP2010035449A
公开(公告)日：2010-02-18
申请号：JP2008199646
申请日：2008-08-01
申请人： Kanazawa Inst Of Technology , Sanko Shoji Kk , 三興商事株式会社 , 学校法人金沢工業大学
发明人： OZEKI KENJI , YAMAMOTO HIROKI , FUJIMOTO NAOKO , WAKAIZUMI MASAKATSU
IPC分类号： C12N1/00 , C12N1/14
摘要： PROBLEM TO BE SOLVED: To provide a method for efficiently and simply screening an acrylamide-degrading microorganism, to provide a culture medium for the same, to provide a kit for the same, and to provide an acrylamide-degrading microorganism obtained by the method.
SOLUTION: Provided are the method for screening the acrylamide-degrading microorganism, in which microorganisms are cultured in a culture medium containing limited concentration of a carbon source and/or a nitrogen source and constant concentration of the acrylamide and then examining the growth states; a culture medium and a kit therefor; and an acrylamide-degrading microorganism obtained by the method.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种有效和简单地筛选丙烯酰胺降解微生物的方法，为其提供用于其的培养基，为其提供试剂盒，并提供通过以下方法获得的丙烯酰胺降解微生物：方法。解决方案：提供了筛选丙烯酰胺降解微生物的方法，其中微生物在含有有限浓度的碳源和/或氮源和恒定浓度的丙烯酰胺的培养基中培养，然后检查生长状态; 培养基及其试剂盒; 和通过该方法获得的丙烯酰胺降解微生物。版权所有（C）2010，JPO＆INPIT

10. 发明专利

JP2019024360A エチル−α−Ｄ−グルコシドの製造方法及びその利用审中-公开
公开(公告)号：JP2019024360A
公开(公告)日：2019-02-21
申请号：JP2017145314
申请日：2017-07-27
申请人： SHATA SHUZO KK , KANAZAWA INST OF TECHNOLOGY
发明人： KURUMADA TOSHIKO , OZEKI KENJI
IPC分类号： C12P19/44 , A61K8/60 , A61K8/9794 , A61Q19/00
摘要：【課題】焼酎醪発酵中に多くのエチル−α−D−グルコシドを容易に製造することが可能になる方法を提供する。【解決手段】清酒粕を含む醪を蒸留し焼酎を製造する工程において、醪にデンプン原料及びα−グルコシターゼを添加して混合する工程と、混合する工程で得られた混合物を15℃以上25℃以下の温度で発酵させる工程と、を含む。デンプン原料は、白糠、米、麦、ソバ、イモ、コーンスターチ又はこれらの混合物である。また、α−グルコシターゼは、清酒粕の重量1に対して重量比0.00075以上0.005以下の割合で添加する。また、白糠は、酒粕の重量1に対して重量比2.5倍量以上15倍量以下の割合で添加する。【選択図】なし

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