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1. 发明专利

JP2013237660A Skin liniment for motor nerve activation 有权
标题翻译：用于电动神经激活的皮肤液
公开(公告)号：JP2013237660A
公开(公告)日：2013-11-28
申请号：JP2012271331
申请日：2012-12-12
申请人： Kao Corp , 花王株式会社
发明人： TOKUNAGA TADAYUKI , TAKAYANAGI NAOTO
IPC分类号： A61K45/00 , A61K31/045 , A61K31/075 , A61K31/16 , A61K31/215 , A61K31/34 , A61P25/00
摘要： PROBLEM TO BE SOLVED: To provide a means for easily activating an motor nerve by the means that does not influence an exercise with almost no influence on a muscle temperature.SOLUTION: A skin liniment for motor nerve activation contains 0.1-10 mass% of a TRPM8 agonist, and is used by applying to a skin before or during an exercise.
摘要翻译：要解决的问题：提供通过不影响几乎不影响肌肉温度的运动的手段来容易地激活运动神经的手段。解决方案：运动神经活化的皮肤搽剂含有0.1-10质量％的 TRPM8激动剂，并且通过在运动之前或期间施用于皮肤来使用。

2. 发明专利

JP2011168557A Liquid composition for oral cavity 有权
标题翻译：口腔用液体组合物
公开(公告)号：JP2011168557A
公开(公告)日：2011-09-01
申请号：JP2010035662
申请日：2010-02-22
申请人： Kao Corp , 花王株式会社
发明人： TOKUNAGA TADAYUKI
IPC分类号： A61K8/63 , A61K8/39 , A61K8/49 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a liquid composition for oral cavity which contains lipophilic β-glycyrrhetinic acid in a stable and effective amount. SOLUTION: The solution offers liquid composition for oral cavity of which pH ranges from 4.5 to 6.0, containing the following ingredients: (A) β-glycyrrhetinic acid or its salt of which the percent composition is 0.006-0.06 mass% in terms of glycyrrhetinic acid; (B) allantoin or its salt of which percent composition is 0.01-0.3 mass% in terms of allantoin; (C) 0.3-5 mass% nonionic surfactant agent; and (D) 50-99 mass% water. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供含有稳定且有效量的亲脂性β-甘草次酸的口腔用液体组合物。解决方案：该溶液提供pH范围为4.5-6.0的口腔液体组合物，含有以下成分：（A）β-甘草次酸或其盐的组成百分比为0.006-0.06质量％的甘草次酸; （B）尿囊素的百分比组成为0.01-0.3质量％的尿囊素或其盐，（C）0.3-5质量％非离子表面活性剂; 和（D）50-99质量％的水。版权所有（C）2011，JPO＆INPIT

3. 发明专利

JPH0543420A COSMETIC 失效
公开(公告)号：JPH0543420A
公开(公告)日：1993-02-23
申请号：JP20591591
申请日：1991-08-16
申请人： KAO CORP
发明人： HASE NOBORU , TOKUNAGA TADAYUKI
IPC分类号： A61K8/19 , A61K8/18 , A61K8/72 , A61K8/89 , A61K8/891 , A61Q1/00 , A61Q1/02 , A61Q1/10 , A61Q1/12
摘要： PURPOSE:To provide a cosmetic favorable in the adherability to the skin, causing little makeup spoilage, and also good to touch. CONSTITUTION:The objective cosmetic can be obtained by formulating, as the essential ingredients, (A) pref. 0.01-40 (esp. 1-20)wt.% of polymethylsilsesquioxane powder, pref. spherical in the particle shape, 0.1-20mum (esp. 2-12mum) in means particle size, more pref. with the particle size distribution falling within + or -30% of the mean size and (B) 0.01-95wt.% of hydrophobicized powder pref. 0.01-80 (esp. 0.05-20)mum in particle size in (C) a makeup cosmetic such as foundation, eye shadow or cheek rouge or (D) base cosmetic such as milky lotion or cream. With the present cosmetic having the above-mentioned effects, such problems resulting from using hydrophobicized powder causing poor touch feeling and bad spreadability will be resolved at a stroke.

4. 发明专利

JPH08295612A COSMETIC 失效
公开(公告)号：JPH08295612A
公开(公告)日：1996-11-12
申请号：JP10578795
申请日：1995-04-28
申请人： KAO CORP
发明人： TOKUNAGA TADAYUKI , TORITSUKA MAKOTO
IPC分类号： A61K8/19 , A61K8/00 , A61K8/18 , A61K8/72 , A61K8/89 , A61K8/92 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/10 , A61Q1/12 , A61Q19/00 , C08L83/08 , A61K7/00 , A61K7/02 , A61K7/48
摘要： PURPOSE: To obtain a cosmetic capable of exhibiting excellent water resistance, sebum resistance, oil resistance, abrasion resistance, etc., and having good make up adhesives. CONSTITUTION: This cosmetic is obtained by combinedly using (A) a semisolid fat or a solid fat (especially preferably a fluorine-modified silicon having a perfluoroalkyl group and having >=30 deg.C maximum endothermic peak by differential scanning calorimeter) with (B) a fluorine compound-treated powder. A fluorine-modified silicone having >=1 structural unit of formula I to formula IV [Rf and Rf ' are each a perfluoroalkyl, etc.; R is an aliphatic hydrocarbon, etc.; R is H, an aliphatic hydrocarbon, etc.; R is a hydrocarbon, etc.; X and Y are each a single bond or CO; (1) is 2-16; (m) and (n) are each 1-16; (p) is 1-200; (r) is 0-5] and a structural unit of formula V [R and R are each R ; (s) is 1-200] and having >=30 deg.C maximum endothermic peak is most suitable for the semisolid fat or the solid fat. The components A and B are each preferably blended in amount of 0.01-99wt.% based on total composition. Further, a liquid lubricant is preferably blended therewith.

5. 发明专利

JPH07216090A FLUORINE-MODIFIED SILICONE, METHOD FOR PRODUCING THE SAME AND COSMETIC CONTAINING THE SAME 失效
公开(公告)号：JPH07216090A
公开(公告)日：1995-08-15
申请号：JP18439394
申请日：1994-08-05
申请人： KAO CORP
发明人： OKADA JOJI , KAWAMATA AKIRA , TOKUNAGA TADAYUKI , TORITSUKA MAKOTO , ASAHI MASAHIKO
IPC分类号： A61K8/00 , A61K8/89 , A61Q1/00 , A61Q1/02 , A61Q1/10 , A61Q1/12 , A61Q5/00 , A61Q19/10 , C08G77/24 , C08G77/38 , C08G77/385 , C08L83/04 , C08L83/08 , A61K7/00 , A61K7/02 , A61K7/06 , A61K7/50
摘要： PURPOSE:To obtain the subject silicone having specific siloxane units, having an excellent water-repelling and oil-repelling property, well compatible with skin, and suitable for cosmetics. CONSTITUTION:This silicone is a fluorine-modified silicone derivative having silicone units of formula I (R is a 1-20C aliphatic hydrocarbon, a 5-10C alicyclic or an aromatic hydrocarbon; (m) is 0-10) and has a polymerization degree of 1-400, preferably the silicone having 1-200 units of formula I and 0-200 silicone units of formula II (R , R are each a 1-20C aliphatic hydrocarbon, a 5-10C alicyclic or an aromatic hydrocarbon).

6. 发明专利

JPH06184312A FLUORINE-MODIFIED SILICONE, ITS PRODUCTION, AND COSMETIC CONTAINING THE SAME 失效
公开(公告)号：JPH06184312A
公开(公告)日：1994-07-05
申请号：JP33414392
申请日：1992-12-15
申请人： KAO CORP
发明人： OKADA JOJI , KAWAMATA AKIRA , TOKUNAGA TADAYUKI , TORITSUKA MAKOTO , ASAHI MASAHIKO
IPC分类号： A61K8/72 , A61K8/18 , A61K8/89 , A61Q1/00 , A61Q1/02 , A61Q1/10 , A61Q1/12 , C08G77/385 , C08G77/46 , C08G81/00 , C08L83/08 , C08L83/12 , A61K7/00 , A61K7/02
摘要： PURPOSE:To obtain the subject silicone which has a high water and oil repellency and gives a cosmetic giving a good feel in use without causing coming off of makeup when compounded into the cosmetic by reacting a silicone deriv. having two specific polysiloxane units with a specific compd. CONSTITUTION:A silicone deriv. having two polysiloxane units of formulae I and II (wherein R , R , and R are each 1-20C linear or branched aliph. hydrocarbon group or a 5-10C alicyclic or arom. hydrocarbon group; and (p) is 1-200 and (q) is 0-200 provided p+q>=6) is reacted with a compd. of formula III [wherein R1 is a 1-20C perfluoroalkyl group or an omega-H-perfluoroalkyl group of the formula: H(CF2)h (wherein (h) is 1-20); R is a 2-16C hydrocarbon group; (m) is 2-16; (n) is 1-6; and (X) is 0-500] to give the objective silicone having two polysiloxane units of formulae IV and V (wherein Rf, R, R , R , (m), (n), (x), (p), and (q) are each as defined above).

7. 发明专利

JPH05247214A 失效
公开(公告)号：JPH05247214A
公开(公告)日：1993-09-24
申请号：JP5164092
申请日：1992-03-10
申请人： KAO CORP
发明人： OKADA JOJI , KAWAMATA AKIRA , TOKUNAGA TADAYUKI , HASE NOBORU , ASAHI MASAHIKO
IPC分类号： A61K8/72 , A61K8/89 , A61Q1/00 , A61Q1/10 , A61Q1/12 , C08G77/22 , C08G77/38 , C08G77/385 , C08G77/46 , C08L83/08 , A61K7/00
摘要： PURPOSE:To obtain a compound excellent in water and oil repellency and suitable for incorporation into a cosmetic preparation by reacting a silicone derivative having two specific kinds of siloxane unit with a specific perfluoroalkyl compound. CONSTITUTION:A silicone derivative having siloxane units represented by formulae I and II (wherein R , R , and R each is a 1-10C aliphatic hydrocarbon group or a 5-10C alicyclic or aromatic hydrocarbon group) and having a degree of polymerization of 2-200 is reacted with a perfluoroalkyl compound represented by formula III (wherein Rf and Rf, each is a 1-20C perfluoroalkyl, l/ is 2-16, and m and n each is 1 or 2) to produce a fluorine-modified silicone derivative having a siloxane unit represented by formula IV (wherein R Rf, R'f, and n are each as defined above) and a siloxane unit represented by formula II and having a degree of polymerization of 2-200. This derivative has excellent water and oil repellency and is suitable for incorporation into a cosmetic preparation and useful as an ingredient for a cosmetic excellent in lasting property and use feeling.

8. 发明专利

JP2009051759A Dentifrice composition 有权
标题翻译： DENTIFRICE组成
公开(公告)号：JP2009051759A
公开(公告)日：2009-03-12
申请号：JP2007218967
申请日：2007-08-24
申请人： Kao Corp , 花王株式会社
发明人： TOKUNAGA TADAYUKI , TONOMURA MANABU
IPC分类号： A61K8/25 , A61K8/73 , A61K8/86 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a dentifrice composition having excellent ability for removing coloring on the surface of the clearance between teeth. SOLUTION: The dentifrice composition comprises (A) 10-30 mass% polishing silica having 10-125 mL/100 g oil absorption, 1-30 μm average particle diameter, 0.15-0.3 g/cm 3 loose apparent specific gravity and 0.25-0.5 g/cm 3 tight apparent specific gravity, and (B) 0.5-30 mass% granules passing through 30 mesh sieve but not passing through 200 mesh sieve. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种具有优异的去除牙齿间隙的着色能力的洁齿剂组合物。＆lt; P＆gt;解决方案：洁牙剂组合物包含（A）10-30质量％的抛光二氧化硅，其具有10-125mL / 100g吸油量，1-30μm平均粒径，0.15-0.3g / cm 3， SP>松散表观比重和0.25-0.5g / cm 3 / SP>紧密表观比重，（B）0.5-30质量％颗粒通过30目筛，但不通过200目筛。版权所有（C）2009，JPO＆INPIT

9. 发明专利

JP2005206592A Oral composition 有权
标题翻译：口腔组成
公开(公告)号：JP2005206592A
公开(公告)日：2005-08-04
申请号：JP2004373075
申请日：2004-12-24
申请人： Kao Corp , 花王株式会社
发明人： TOKUNAGA TADAYUKI , OSHINO KAZUSHI
IPC分类号： A61K8/365 , A61K8/00 , A61K8/21 , A61K8/34 , A61K8/36 , A61Q11/00 , A61K7/24 , A61K7/16 , A61K7/18
摘要： PROBLEM TO BE SOLVED: To provide an oral composition containing monofluorophosphoric acid with which stable supply of calcium ions is possible.
SOLUTION: The oral composition comprises an ingredient (A): a calcium ion supply compound for supplying 100-16000ppm calcium ion, an ingredient (B): a monofluorophosphate ion-supplying compound for supplying 250-25000ppm monofluorophosphate ion and an ingredient (C): one or more species of acids selected from the group consisting of lactic acid, malic acid, citric acid and tartaric acid and has pH4-6.2.
COPYRIGHT: (C)2005,JPO&NCIPI

10. 发明专利

JP2003238372A COMPOSITION FOR ORAL CAVITY 审中-公开
公开(公告)号：JP2003238372A
公开(公告)日：2003-08-27
申请号：JP2002043415
申请日：2002-02-20
申请人： KAO CORP
发明人： OSHINO KAZUSHI , HOSOYA MANABU , TOI MANABU , TOKUNAGA TADAYUKI , MAEDA AKITSUGU
IPC分类号： A61K8/21 , A61K8/34 , A61K31/047 , A61P1/02 , A61P43/00 , A61Q11/00 , A61K7/18
摘要： PROBLEM TO BE SOLVED: To provide a composition which is used for oral cavities and enables the efficient intake of fluorine in the teeth to give an excellent recalcification- promoting effect. SOLUTION: This composition for oral cavities comprises (A) the first composition containing a calcium ion-supplying compound capable of 50 to 16,000 ppm of calcium ion, and a monofluorophosphate ion-supplying compound, and (B) the second composition containing a fluoride ion-supplying compound, wherein the components (A) and (B) are mixed with each other in the oral cavity or just before charged in the oral cavity. COPYRIGHT: (C)2003,JPO

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