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    • 5. 发明专利
    • CHIRAL OXAZOLINE DERIVATIVE
    • JPH05202010A
    • 1993-08-10
    • JP28116392
    • 1992-09-28
    • HOFFMANN LA ROCHE
    • SUTEFUAN KERIIRIHIYARUTO BUHETSUKERU
    • C07D263/10C07D263/12C07D263/14C07D413/04C07D413/06C07D413/08C07D413/10C07D413/12C07D413/14C09K19/34C09K19/42C09K19/58G02F1/13
    • Optically active compounds of the formula in which n is the number 0 or 1, R is an R group or a group of the formula A , A and A , independently of one another, are 1,4-phenylene which is unsubstituted or monosubstituted or polysubstituted by halogen, cyano and/or methyl and in which, if unsubstituted, one or two CH groups have optionally been replaced by nitrogen, or are trans-1,4-cyclohexylene, trans-1,3-dioxane-2,5-diyl, bicyclo[2.2.2.]octane-1,4-diyl, naphthalene-2,6-diyl, tetralin-2,6-diyl or trans-decalin-2,6-diyl, Z and Z , independently of one another, are a single covalent bond or -CH2CH2-, Z and Z , independently of one another, are a single covalent bond, -CH2-CH2-, -COO-, -OOC-, -CH2O-, -OCH2-, -C IDENTICAL C-, -(CH2)4, -(CH2)3O-, -O(CH2 )3- or the trans-form of -CH=CH-CH2CH2-, -CH2CH2-CH=CH-, -CH=CH-CH2O- or -OCH2-CH=CH-, R and R , independently of one another, are alkyl having 1 to 12 carbon atoms, alkoxymethyl having 2 to 12 carbon atoms, p-alkoxyphenyl or p-alkoxy benzyl, R and R , independently of one another, are hydrogen, alkyl having 1 to 12 carbon atoms or phenyl, R and R , independently of one another, are hydrogen, alkyl having 1 to 12 carbon atoms, phenyl or alkoxycarbonyl having 2 to 12 carbon atoms, with the proviso that R and R are not simultaneously hydrogen, R is alkyl or alkenyl having 1 or 2 to 9 carbon atoms respectively which is unsubstituted or monosubstituted or polysubstituted by fluorine and in which one -CH2- group may be replaced by -O-, R is hydrogen, halogen, cyano, trifluoromethyl, trifluoromethoxy, or alkyl or alkenyl having 1 or 2 to 12 carbon atoms respectively which is unsubstituted or monosubstituted or polysubstituted by halogen, cyano and/or methyl and in which one or two non-adjacent methylene groups may be replaced by -O-, -COO- and/or -OOC-, and the oxazoline ring shown in formula (I) is in optically active form, liquid-crystalline mixtures which contain such dopants, and the use thereof for optical and electro-optical purposes.