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    • 2. 发明专利
    • Testosterone 5α- reductase activity inhibitors, androgen receptor antagonists, method of inhibiting its use, and androgen activity expression
    • 空值
    • JP5000964B2
    • 2012-08-15
    • JP2006268347
    • 2006-09-29
    • 株式会社コーセー
    • 静香 上原
    • A61K8/97A61K36/18A61P17/08A61P17/10A61P17/16A61Q1/02A61Q7/00A61Q19/00
    • PROBLEM TO BE SOLVED: To provide a new testosterone 5α-reductase activity inhibitor, to provide a new androgen receptor antagonist, to provide a hair tonic, to provide a skin care preparation for preventing/improving acne, to provide a skin care preparation for inhibiting sebum secretion, and to provide a method for inhibiting androgen activity expression. SOLUTION: Provided are the testosterone 5α-reductase activity inhibitor containing a Chloranthus japonicus extract as an active ingredient, the androgen receptor antagonist containing the Chloranthus japonicus extract as an active ingredient, the hair tonic containing their agents, the skin care preparation for preventing/improving acne, and the skin care preparation for inhibiting sebum secretion containing the agents. A method for inhibiting androgen activity expression comprising supplying the Chloranthus japonicus extract is also provided. COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供新的睾酮5α-还原酶活性抑制剂,以提供新的雄激素受体拮抗剂,以提供滋养滋养剂,以提供用于预防/改善痤疮的护肤制剂,以提供皮肤护理 制备抑制皮脂分泌的方法,提供抑制雄激素活性表达的方法。 提供了含有日本黄花提取物作为活性成分的睾酮5α-还原酶活性抑制剂,含有黄花提取物作为活性成分的雄激素受体拮抗剂,含有它们的药剂的护发剂, 防止/改善痤疮,以及用于抑制含有药剂的皮脂分泌的护肤制剂。 还提供了一种抑制雄激素活性表达的方法,包括供应黄竹提取物。 版权所有(C)2008,JPO&INPIT