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1. 发明专利

JP2010148451A Cell treatment device 审中-公开
标题翻译：细胞处理装置
公开(公告)号：JP2010148451A
公开(公告)日：2010-07-08
申请号：JP2008331032
申请日：2008-12-25
申请人： Cytori Therapeutics Inc , Olympus Corp , オリンパス株式会社 , サイトリセラピューティクスインコーポレイテッド
发明人： YOSHIDA KAZUHIRO , ROBERT K SHANAHAN , LUCAS V FORNACE
IPC分类号： C12M1/10
CPC分类号： C12M47/04 , C12M33/10
摘要： PROBLEM TO BE SOLVED: To efficiently cleanse cell clusters to collect the cell clusters removed from unnecessary components (impurities).
SOLUTION: A cell treatment device 1 includes: a vessel body 4 including a cylindrically surfaced sidewall 4a, and a plurality of recessed parts 4b outside radially at spacings in the direction of the circumference of the sidewall 4a, wherein the vessel body is rotated around the central axis of the sidewall 4a with a cell suspension contained; a cleansing liquid feed pipe 6 with outlets 6a disposed near the bottom surface of each of the recessed parts 4b; and a suction pipe 5 with suction ports 5a disposed standing against the sidewall 4a among mutually adjacent recessed parts 4b.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：有效地清洁细胞簇以收集从不必要的成分（杂质）中去除的细胞簇。解决方案：电池处理装置1包括：容器主体4，其包括圆柱形表面侧壁4a;以及多个凹陷部分4b，其沿侧壁4a的圆周方向的间隔径向外侧，其中容器主体是围绕所述侧壁4a的中心轴旋转，其中包含细胞悬浮液; 具有设置在每个凹部4b的底面附近的出口6a的清洁液体供给管6; 以及具有吸引口5a的抽吸管5，其设置成相互相邻的凹部4b中的侧壁4a。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2010148450A Method for cleaning cell 审中-公开
标题翻译：清洁细胞的方法
公开(公告)号：JP2010148450A
公开(公告)日：2010-07-08
申请号：JP2008331031
申请日：2008-12-25
申请人： Cytori Therapeutics Inc , Olympus Corp , オリンパス株式会社 , サイトリセラピューティクスインコーポレイテッド
发明人： TSUCHIDA HIRONORI , KARASAWA CHISATO , YOSHIDA KAZUHIRO , ROBERT K SHANAHAN , LUCAS V FORNACE
IPC分类号： C12N5/07 , B04B11/04 , B04B15/12 , C12N1/02
CPC分类号： B04B5/0421 , B04B15/12 , C12M47/12
摘要： PROBLEM TO BE SOLVED: To recover cells removed with unnecessary components by efficiently cleaning the cells. SOLUTION: This method for cleaning the cells is provided by comprising a centrifugal separation process S1 of housing cell suspension in a centrifugal container having an ejection port of cleaning liquid opposite to its bottom part, and centrifugally separating the cells to the bottom part by rotating so that the bottom part faces in radial directional outer direction, a supernatant-discharging process S2 for discharging the centrifugally separated supernatant in the centrifugally separating process S1, and a cleaning process S3 of ejecting the cleaning liquid from the ejection port in a state that the supernatant is discharged in the supernatant-discharging process S2, and the centrifugal container is rotated. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：通过有效地清洁细胞来回收利用不必要的成分去除的细胞。解决方案：这种清洗电池的方法是通过将壳体电池悬浮液的离心分离过程S1包括在具有与其底部相对的清洗液的喷射口的离心容器中提供的，并将电池离心分离到底部通过旋转使得底部部分面向径向外向，在离心分离过程S1中排出离心分离的上清液的上清液排放过程S2和在一个状态下从排出口喷射清洗液的清洗过程S3 在上清液排出工序S2中排出上清液，离心容器旋转。版权所有（C）2010，JPO＆INPIT

3. 发明专利

JP2013117562A Imaging unit and manufacturing method thereof 有权
标题翻译：成像单元及其制造方法
公开(公告)号：JP2013117562A
公开(公告)日：2013-06-13
申请号：JP2011263764
申请日：2011-12-01
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO
IPC分类号： G02B7/02 , H04N5/225
CPC分类号： H04N5/2254 , G02B7/021 , G02B7/023 , H01L27/14618 , H01L2924/0002 , H04N5/2257 , Y10T29/49002 , H01L2924/00
摘要： PROBLEM TO BE SOLVED: To provide a small-diameter imaging unit 10 that can be assembled easily.SOLUTION: An imaging unit 10 includes an imaging device chip 20 in a rectangular form in plane view, a transparent substrate 30 having the same dimension in plan view as that of the imaging device chip 20 and joined thereto, and a lens unit 70 joined to the transparent substrate 30 in a state where an optical axis O and the center C of a light receiver 21 of the imaging device chip are aligned each other. Two engaging parts 33X, 33Y are formed on the transparent substrate 30. Two engaging parts 51X, 51Y of the lens unit 70 having a dimension in plane view equal to or smaller than that of the imaging device chip 20 are fitted with or abutted against the corresponding engaging parts 33X, 33Y, respectively.
摘要翻译：要解决的问题：提供可以容易地组装的小直径成像单元10。解决方案：成像单元10包括平面图中矩形形状的成像装置芯片20，在与成像装置芯片20的平面图中具有相同尺寸并与之连接的透明基板30，以及透镜单元 70在成像装置芯片的光接收器21的光轴O和中心C彼此对准的状态下接合到透明基板30。两个接合部分33X，33Y形成在透明基板30上。具有等于或小于成像装置芯片20的尺寸的透镜单元70的两个接合部分51X，51Y装配或抵靠相应的接合部分33X，33Y。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2006132986A Optical biological information measuring instrument and measuring method using it 审中-公开
标题翻译：光学生物信息测量仪器和使用它的测量方法
公开(公告)号：JP2006132986A
公开(公告)日：2006-05-25
申请号：JP2004319727
申请日：2004-11-02
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO , KIMURA ATSUSHI
IPC分类号： G01N21/27 , A61B5/145
摘要： PROBLEM TO BE SOLVED: To enhance a measuring precision by suppressing fluctuations in a spectroscope performance for spectrally diffracting the light from a light source having wavelength characteristics.
SOLUTION: The optical physiological data measuring instrument 1 is equipped with a light source 2 having wavelength characteristics changed in light intensity with respect to a wavelength, a spectroscope 16 for spectrally diffracting the light over a predetermined wavelength band from the light source 2 and a control unit 17 for controlling the wavelength of the light emitted from the spectroscope 16. The control units 17 controls the emitted pattern of a wavelength so as to reduce the temporal change in the intensity of the light emitted from the spectroscope 16.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过抑制从具有波长特性的光源衍射光的分光镜性能的波动来提高测量精度。解决方案：光学生理数据测量仪器1配备有具有相对于波长的光强度变化的波长特性的光源2，用于从光源2在预定波长带上对光进行光谱衍射的分光镜16 以及用于控制从分光器16发射的光的波长的控制单元17.控制单元17控制发射的波长图案，以便减少从分光器16发射的光的强度的时间变化。
版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2006000181A Optical biological information measuring apparatus 审中-公开
标题翻译：光学生物信息测量装置
公开(公告)号：JP2006000181A
公开(公告)日：2006-01-05
申请号：JP2004176926
申请日：2004-06-15
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO , AOKI ISAO , NAKANO TAKUYA , ITSUGA KOHEI
IPC分类号： A61B5/145 , A61B5/00 , A61B5/01 , A61B5/026 , A61B5/107 , A61B5/1455 , G01N21/35 , G01N21/3577 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To provide an optical biological information measuring apparatus capable of accurately recognizing various factors such as the conditions of a person to be measured and measuring accurate biological information in the case of noninvasively measuring the biological information at the forearm of the person to be measured. SOLUTION: The optical biological information measuring apparatus comprises an armrest part for mounting the forearm B of the person to be measured in a positioned state, an optical measurement head 5 made to tightly adhere to the forearm mounted on the armrest part, and a moving mechanism for relatively moving the optical measurement head 5 or the armrest part and making the optical measurement head 5 adhere to the forearm B. The optical measurement head 5 is provided with a photodetection part 41 for irradiating the inside of the forearm B with light and detecting return light and is also provided with at least one of a moisture detection part 43 for detecting the moisture content of the skin, a fat detection part 44 for detecting a fat amount, a blood flow detection part 42 for detecting a blood flow amount and a body temperature detection part 45 for detecting a body temperature, and the photodetection part 41 and the other detection parts 42-46 are arranged along the longitudinal direction of the forearm B. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种光学生物信息测量装置，其能够在非侵入性地测量前臂上的生物信息的情况下，准确地识别诸如待测量人的状况的各种因素，并测量精确的生物信息被测量的人。解决方案：光学生物信息测量装置包括用于将待测人员的前臂B安装在定位状态的扶手部分，紧贴于安装在扶手部件上的前臂的光学测量头5，以及用于相对移动光学测量头5或扶手部分并使光学测量头5粘附到前臂B的移动机构。光学测量头5设置有用于用光照射前臂B的内部的光电检测部41 并检测返回光，并且还设置有用于检测皮肤含水量的水分检测部43，用于检测脂肪量的脂肪检测部44中的至少一个，用于检测血液流量的血流量检测部42 以及用于检测体温的体温检测部45，并且沿着纵向配置光检测部41和其他检测部42〜46 前臂的方向B.版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2004294075A Glucose concentration meter 审中-公开
公开(公告)号：JP2004294075A
公开(公告)日：2004-10-21
申请号：JP2003082770
申请日：2003-03-25
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： KANEKO MAMORU , YOSHIDA KAZUHIRO , ONO WATARU , SASAI TSUGUHISA , UEHARA YASUHIRO , IMAI HIDENOBU , ARIFUKU KIYOSHI , HIEDA MASAYA , SATO KOHEI , NAKANO TAKUYA
IPC分类号： G01N33/483 , A61B5/145 , A61B5/1455 , G01N21/17 , G01N21/35 , G01N21/3577 , G01N21/359 , G01N33/66
摘要： PROBLEM TO BE SOLVED: To provide a glucose concentration meter that is noninvasive and has high measurement precision. SOLUTION: The glucose densitometer comprises an optical fiber 5 that is arranged on an organism surface S1 for irradiating the inside of an organism S with near infrared light; a plurality of optical fibers 6 for detecting diffused light in the organism S from outside the organism S; and a computing means for obtaining glucose concentration, based on these received light signals. The respective optical fibers 6 have an optical fiber 6B that has a light reception end at an equal distance from the light irradiation end of the optical fiber 5 and is arranged at an inclination angle toward a relatively deep light reception direction; and an optical fiber 6A arranged with an inclination angle toward a shallow light reception direction. The computing means adopts a configuration for obtaining glucose concentration, based on the difference of the light reception signal of the optical fiber 6A from which the light reception signal of the optical fiber 6B is subtracted. COPYRIGHT: (C)2005,JPO&NCIPI

7. 发明专利

JP2014200551A 穿刺針有权
标题翻译：针刺针
公开(公告)号：JP2014200551A
公开(公告)日：2014-10-27
申请号：JP2013080528
申请日：2013-04-08
申请人：オリンパス株式会社 , Olympus Corp
发明人： YOSHIDA KAZUHIRO
IPC分类号： A61M5/32 , A61B17/34 , A61M19/00
CPC分类号： A61B17/3478 , A61B17/3417 , A61B2017/00305 , A61B2017/00309 , A61B2017/00314
摘要：【課題】刃先が心臓に接触することを確実に防ぎながら心膜腔内へ容易に挿入する。【解決手段】細長い略直線状の本体2と、該本体2の先端側に位置し、長手方向に対して斜めに形成された先端面からなる刃面31を有する先端部3と、本体2と先端部3との間に設けられて本体2と先端部3とを接続するとともに、外力に従って受動的に湾曲可能な湾曲部4と、該湾曲部4の湾曲方向を、刃面31を湾曲形状の内方に向ける方向に規定する湾曲方向制御手段3とを備える穿刺針1を提供する。【選択図】図1
摘要翻译：要解决的问题：提供一种容易插入心包腔的穿刺针，同时可靠地防止刀刃与心脏接触。解决方案：穿刺针1包括：细长线状体2; 远端部3位于主体2的前端侧，具有由相对于长度方向倾斜地形成的前端面构成的叶片面31; 设置在主体2和远端部3之间用于连接主体2和远端部3并被外力被动地弯曲的弯曲部分4; 以及弯曲方向控制装置3，其将弯曲部分4的弯曲方向调节到叶片表面31朝向弯曲形状的内侧的方向。

8. 发明专利

JP2012254176A Imaging device 有权
标题翻译：成像装置
公开(公告)号：JP2012254176A
公开(公告)日：2012-12-27
申请号：JP2011128619
申请日：2011-06-08
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO
IPC分类号： A61B1/04 , A61B1/00 , G02B23/24 , G02B23/26 , H04N5/225 , H04N5/335
CPC分类号： H04N5/369 , A61B1/00163 , A61B1/051
摘要： PROBLEM TO BE SOLVED: To provide an imaging device enabling a decrease in the diameter of an endoscope insertion part by thinning a solid imaging element and easy to handle.SOLUTION: The imaging device 1 comprises: the solid imaging element 2 having a substrate 2a, one surface of which is sectioned into a light-receiving part region A2b in which a light-receiving part 2b is provided that generates an imaging signal of an optical image of a subject, a circuit part region A2c in which a circuit part 2c is provided that performs signal processing of a generated imaging signal and generates a driving signal for driving the light-receiving part 2b, and a terminal part region A2d in which a plurality of electrode pads 2d are provided; and an objective optical part 3 having an objective lens unit 4 comprising a unit body 7 with an objective lens group 7b for imaging an optical image of a subject and a holding frame 6 to which the unit body 7 is fixed, and a prism 5 for guiding the optical image passed through the objective lens unit 4 to the light-receiving part 2b of the solid imaging element 2. The prism 5 is disposed on the light-receiving part region A2b of the substrate 2a, and the holding frame 6 is disposed on the circuit part region A2c.
摘要翻译：要解决的问题：提供一种能够通过使固体成像元件变薄并易于处理而能够减小内窥镜插入部的直径的成像装置。成像装置1包括：固体成像元件2，其具有基板2a，基板2a的一个表面被分割成光接收部分区域A2b，其中设置有受光部分2b，其产生成像信号拍摄对象的光学图像的电路部分区域A2c，其中设置有电路部分2c的电路部分2c，其执行产生的成像信号的信号处理并产生用于驱动光接收部分2b的驱动信号，以及端子部分区域A2d 其中设置有多个电极焊盘2d; 以及具有物镜4的对象光学部件3，该物镜单元4包括具有用于对被摄体的光学图像进行成像的物镜组7b的单元体7和固定有单元体7的保持框6;以及棱镜5，将通过物镜单元4的光学图像引导到固体摄像元件2的光接收部分2b。棱镜5设置在基板2a的受光部区域A2b上，并且保持框架6被布置在电路部分区域A2c上。版权所有（C）2013，JPO＆INPIT

9. 发明专利

JP2012015470A Imaging device, and method of manufacturing the same 有权
标题翻译：成像装置及其制造方法
公开(公告)号：JP2012015470A
公开(公告)日：2012-01-19
申请号：JP2010153462
申请日：2010-07-05
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO
IPC分类号： H01L27/14 , H01L23/12 , H04N5/369
CPC分类号： H01L31/02327 , H01L23/3114 , H01L27/14618 , H01L27/14623 , H01L27/14634 , H01L27/14636 , H01L27/1469 , H01L31/18 , H01L2924/0002 , H04N5/2253 , H04N5/33 , H01L2924/00
摘要： PROBLEM TO BE SOLVED: To provide an imaging device 1 with a stable imaging operation.SOLUTION: An imaging device 1 has: an imaging element 13 formed on a first main surface 11A of a silicone substrate 11; an electrode pad 14 formed on the first main surface 11A; a front surface wiring 12 connecting the imaging element 13 with the electrode pad 14; an external connection terminal 20 formed on a second main surface 11B of the silicone substrate 11; a rear surface wiring 19 connecting the electrode pad 14 with the external connection terminal 20 via a substrate through-hole 18 that penetrates the silicone substrate 11 from the second main surface 11B side and reaches to a rear surface of the electrode pad 14; and a light shielding layer 22 formed on the second main surface 11B, and that covers a groove part 21 surrounding the imaging element 13 and a region surrounded by the groove part 21.
摘要翻译：要解决的问题：提供具有稳定成像操作的成像装置1。解决方案：成像装置1具有：形成在硅树脂基板11的第一主表面11A上的成像元件13; 形成在第一主表面11A上的电极焊盘14; 将摄像元件13与电极焊盘14连接的前面布线12; 形成在硅树脂基板11的第二主表面11B上的外部连接端子20; 通过从第二主表面11B侧穿透有机硅基板11并到达电极焊盘14的后表面的基板通孔18将电极焊盘14与外部连接端子20连接的背面布线19; 以及形成在第二主表面11B上并且覆盖围绕成像元件13的凹槽部分21和由凹槽部分21包围的区域的遮光层22.版权所有（C）2012，JPO＆INPIT

10. 发明专利

JP2004321572A Glucose densitometry apparatus 审中-公开
公开(公告)号：JP2004321572A
公开(公告)日：2004-11-18
申请号：JP2003122144
申请日：2003-04-25
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： AOKI ISAO , HAMANO MASAHIKO , TAKAHASHI YASUSHI , UEHARA YASUHIRO , ONO WATARU , YOSHIDA KAZUHIRO , ARIFUKU KIYOSHI
IPC分类号： G01N21/01 , A61B5/145 , A61B5/1455 , G01N21/35 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To increase a measurement precision in not invasive glucose densitometry by restraining a fluctuation in a measurement condition of a region of measurement. SOLUTION: A glucose densitometry apparatus 1 is equipped with a detection head 7 which is disposed on a surface of a living body A, illuminates light into the living body A and detects the light which diffuses in or penetrates through the living body A outside of the living body A, with which a glucose concentration in the living body A is calculated based on the detected spectrum of the light. Also, position determination means 4, 5 and 6 to determine positioning of the detection head 7 are disposed on the surface of the living boy A. COPYRIGHT: (C)2005,JPO&NCIPI

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