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1. 发明专利

JP2006141636A Optical biological information measuring instrument 审中-公开
标题翻译：光学生物信息测量仪器
公开(公告)号：JP2006141636A
公开(公告)日：2006-06-08
申请号：JP2004334871
申请日：2004-11-18
申请人： Olympus Corp , オリンパス株式会社
发明人： NAKANO TAKUYA , YOSHIDA KAZUHIRO
IPC分类号： A61B5/145 , A61B5/1455 , G01N21/27 , G01N21/35 , G01N21/3577 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To dissolve the dispersion of measured results of respective measurements as much as possible and to provide stable measured results. SOLUTION: An optical biological information measuring instrument comprises: an armrest part for mounting the forearm A of a person to be measured in a positioned state; an optical measurement head 3 fixed at the upper part of the armrest part and provided with a fiber bundle 6 whose distal end face 6a is to be tightly adhered to the upper surface of the forearm A mounted on the armrest part; and a moving mechanism for moving the armrest part and tightly adhering the optical measurement head 3 to the forearm A. The optical measurement head 3 is provided with a fitting part 10, a part 11 to be fitted for fitting the fitting part 10 is fixed to the upper surface of the forearm A of the person to be measured, and the fitting part 10 and the part 11 to be fitted are provided with engaging parts 12 and 18 to be engaged so as to fit the fitting part 10 and the part 11 to be fitted with each other at a prescribed position around the axis of the fiber bundle 6 to the forearm A of the person to be measured. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：尽可能多地溶解测量结果的分散度，并提供稳定的测量结果。光学生物信息测量仪器包括：用于将待测人员的前臂A安装在定位状态的扶手部分; 光学测量头3固定在扶手部分的上部，并且设置有将前端面6a紧紧地粘附到安装在扶手部分上的前臂A的上表面的纤维束6; 以及用于移动扶手部分并将光学测量头3紧密地粘附到前臂A的移动机构。光学测量头3设置有配件部分10，将用于装配配件部件10的部件11固定到要测量人员的前臂A的上表面以及装配部分10和待装配的部分11设置有接合部分12和18，以接合以将装配部分10和部分11装配到在围绕纤维束6的轴线的规定位置处彼此配合到被测量人物的前臂A. 版权所有（C）2006，JPO＆NCIPI

2. 发明专利

JP2005304822A Glucose concentration measuring instrument 审中-公开
标题翻译：葡萄糖浓度测量仪器
公开(公告)号：JP2005304822A
公开(公告)日：2005-11-04
申请号：JP2004126650
申请日：2004-04-22
申请人： Olympus Corp , オリンパス株式会社
发明人： KANEKO MAMORU , YOSHIDA KAZUHIRO , UEHARA YASUHIRO , NAKANO TAKUYA
IPC分类号： G01N21/35 , A61B5/145 , A61B5/1455 , G01N21/3577 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To improve the measurement accuracy by stabilizing the quantity of a light irradiating an organism. SOLUTION: This glucose concentration measuring instrument 1 is provided with a light source 2 emitting a light irradiating the organism A, a spectroscope 7 spectrally diffracting the light emitted from the light source 2, an optical probe 25 comprising an irradiating optical fiber 11 which guides the light spectrally diffracted by the spectroscope 7 to the surface of the organism A, and a light receiving optical fiber 12 which receives the light scattered or transmitted in the internal of the organism A, and an optical detector 5 detecting the light received and propagated by the light receiving optical fiber 12. This measuring instrument 1 measures the glucose concentration in the internal of the organism A based on the absorbency in respective wavelengths and is disposed with an excitor 17 removing an unnecessary mode in the light while the light spectrally diffracted by the spectroscope 7 is guided to the irradiating optical fiber 11. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过稳定照射生物体的光量来提高测量精度。解决方案：该葡萄糖浓度测量仪1设置有发射照射生物A的光的光源2，对从光源2发射的光进行光谱衍射的分光镜7，包括照射光纤11的光学探针25 其将由分光镜7的光谱衍射的光引导到生物体A的表面;以及受光光纤12，其接收在生物体A的内部散射或透射的光，以及光检测器5，其检测所接收的光和该测量仪器1基于各波长的吸收度测量生物体A的内部的葡萄糖浓度，并且设置有激光器17，在光线衍射时除去不需要的模式通过分光镜7被引导到照射光纤11.版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2004321368A Apparatus for measuring glucose concentration 审中-公开
公开(公告)号：JP2004321368A
公开(公告)日：2004-11-18
申请号：JP2003118204
申请日：2003-04-23
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： KANEKO MAMORU , SASAI TSUGUHISA , HIEDA MASAYA , NAKANO TAKUYA , SATO KOHEI , ARIFUKU KIYOSHI
IPC分类号： G01N21/01 , A61B5/145 , A61B5/1455 , A61B5/1495 , G01N21/35 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To offer a noninvasion apparatus for measuring glucose concentration in which very precise and exact measuring is performed by controlling the influence of a temperature fluctuation of a living body. SOLUTION: The apparatus is arranged on the surface of the living body A and has a light section 6 which applies to the inside of the living body as irradiation light near infrared light, a detector 7 which detects in the outside of the living body diffused light which has diffused within the living body, an arithmetic means 18 to determine glucose concentration within the living body based on the spectrum of light detected by the detector, and a temperature sensor S1 which measures temperature on the surface of the living body. The arithmetic means calibrates the glucose concentration according to the temperature measured with the temperature sensor. COPYRIGHT: (C)2005,JPO&NCIPI

4. 发明专利

JP2006000182A Optical biological information measuring apparatus 审中-公开
标题翻译：光学生物信息测量装置
公开(公告)号：JP2006000182A
公开(公告)日：2006-01-05
申请号：JP2004176927
申请日：2004-06-15
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO , AOKI ISAO , NAKANO TAKUYA
IPC分类号： A61B5/145
摘要： PROBLEM TO BE SOLVED: To provide an optical biological information measuring apparatus capable of preventing the fluctuation of a contact state between the forearm of a person to be measured and a measurement head, preventing a measurement state from being different for each person to be measured and accurately executing the measurement for two or more times with high reproducibility. SOLUTION: The optical biological information measuring apparatus comprises an armrest part 3 for mounting the forearm B of the person to be measured in a positioned state, an optical measurement head 5 made to tightly adher to the forearm B mounted on the armrest part 3, a moving mechanism 4 for relatively moving the optical measurement head 5 or the armrest part 3 in a horizontal direction and making the optical measurement head 5 adhere to the forearm B, and a pressure detection part 45 provided in the optical measurement head 5 for detecting contact pressure with the forearm B. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决的问题：提供一种光学生物信息测量装置，其能够防止被测量人的前臂与测量头之间的接触状态的波动，从而防止测量状态对于每个人而不同以高再现性测量并准确地执行测量两次或更多次。解决方案：光学生物信息测量装置包括用于将被测量人员的前臂B安装在定位状态的扶手部分3，紧固到安装在扶手部分上的前臂B的光学测量头5 3是用于使光学测量头5或扶手部3在水平方向上相对移动并使光学测量头5粘附到前臂B的移动机构4以及设在光学测量头5中的压力检测部45，检测与前臂B的接触压力。版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2006000180A Optical biological information measuring apparatus 审中-公开
标题翻译：光学生物信息测量装置
公开(公告)号：JP2006000180A
公开(公告)日：2006-01-05
申请号：JP2004176925
申请日：2004-06-15
申请人： Olympus Corp , オリンパス株式会社
发明人： YOSHIDA KAZUHIRO , NAKANO TAKUYA , ITSUGA KOHEI
IPC分类号： A61B5/145
摘要： PROBLEM TO BE SOLVED: To provide an optical biological information measuring apparatus capable of performing measurement in a rest state without completely restraining the forearm of a person to be measured and executing the measurement for two or more times with high reproducibility. SOLUTION: The optical biological information measuring apparatus 1 comprises an armrest part 3 for mounting the forearm B of the person to be measured in a positioned state, an optical measurement head 5 made to tightly adhere to the forearm B mounted on the armrest part 3, and a moving mechanism 4 for relatively moving the optical measurement head 5 or the armrest part 3 and making the optical measurement head 5 tightly adhere to the forearm B. The armrest part 3 is provided with a first butting part 15 for butting the palm B1 of the person to be measured, a second butting part 16 for butting the elbow B2 of the person to be measured and a third butting part 18 arranged at a position facing the optical measurement head 5 across the mounted forearm B. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决的问题：提供一种光学生物信息测量装置，其能够在没有完全限制被测量人的前臂的情况下进行静止状态的测量，并以高再现性执行两次以上的测量。解决方案：光学生物信息测量装置1包括用于将被测量人员的前臂B安装在定位状态的扶手部分3，紧固地粘附到安装在扶手上的前臂B的光学测量头5 第3部分，以及用于相对移动光学测量头5或扶手部分3并使光学测量头5紧密地粘附到前臂B的移动机构4.扶手部分3设有第一对接部分15，要测量的人的手掌B1，用于对接被测量人的肘部B2的第二对接部分16和布置在面向光学测量头5的位置穿过所安装的前臂B的第三对接部分18。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2005224536A Glucose concentration measuring device 审中-公开
标题翻译：葡萄糖浓度测量装置
公开(公告)号：JP2005224536A
公开(公告)日：2005-08-25
申请号：JP2004038954
申请日：2004-02-16
申请人： Olympus Corp , オリンパス株式会社
发明人： SUEHIRO KENJI , NAKANO TAKUYA
IPC分类号： G01N21/35 , A61B5/145 , A61B5/1455 , G01N21/3577 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To efficiently detect the light of various wavelength bands so as to accurately measure a glucose concentration in non-invasive glucose concentration measurement. SOLUTION: A glucose concentration measuring device 1 comprises: a light source for generating the light to irradiate a living body A; a light irradiation part 27 for irradiating the living body A with the light led from the light source 2; a reflected light receiving part 29 which is arranged adjacently to the light irradiation part 27 and receives reflected light diffused inside the living body A; a transmitted light receiving part 31 which is arranged facing the light irradiation part 27 across the living body A and receives the transmitted light transmitted through the living body A; a photodetection part for detecting the light received in the light receiving parts 29 and 31; and an arithmetic part for calculating the glucose concentration inside the living body on the basis of the spectrum of the light detected by the photodetection part. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了有效地检测各种波长带的光，以准确地测量非侵入性葡萄糖浓度测量中的葡萄糖浓度。解决方案：葡萄糖浓度测量装置1包括：用于产生照射生物体A的光的光源; 用于用从光源2引出的光照射生物体A的光照射部27; 与光照射部27相邻配置的反射光接收部29，并且接收在生物体A内部扩散的反射光; 穿过生物体A布置成面向光照射部27的透射光接收部31，并接收透过生物体A的透射光; 用于检测在光接收部分29和31中接收的光的光电检测部分; 以及运算部，其基于由光检测部检测出的光的光谱计算生物体内的葡萄糖浓度。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2005192612A Glucose concentration measuring apparatus 审中-公开
标题翻译：葡萄糖浓度测量仪器
公开(公告)号：JP2005192612A
公开(公告)日：2005-07-21
申请号：JP2003435182
申请日：2003-12-26
申请人： Olympus Corp , オリンパス株式会社
发明人： KANEKO MAMORU , YOSHIDA KAZUHIRO , NAKANO TAKUYA
IPC分类号： G01N21/27 , A61B5/145 , A61B5/1455
摘要： PROBLEM TO BE SOLVED: To improve a measurement precision by increasing an S/N ratio in a non-invasive glucose concentration measurement.
SOLUTION: The glucose concentration measuring apparatus 1 comprises: an apparatus main body 31 provided with a light source 2 and a single intra-apparatus optical fiber 32 for leading light emitted from the light source 2; a measuring probe 40 arranged in the state of being in contact with the surface of a living body A for emitting the light from the light source 2 into the living body A; and an optical fiber 41 for irradiation for detachably connecting the apparatus main body 31 and the measuring probe 40. The glucose concentration measuring apparatus 1 is attached to the apparatus main body 31 in the state that one end face of the optical fiber 41 for the irradiation is fixed to the tip surface 40a of the measuring probe 40 and the other end face is abutted to the end face of the intra-apparatus optical fiber 32.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：通过增加非侵入性葡萄糖浓度测量中的S / N比来提高测量精度。葡萄糖浓度测量装置1包括：设置有用于引导从光源2发射的光的光源2和单个设备内光纤32的设备主体31; 测量探针40，其以与活体A的表面接触的方式配置，用于将来自光源2的光发射到生物体A中; 以及用于可拆卸地连接设备主体31和测量探头40的照射用光纤41.葡萄糖浓度测量设备1在用于照射的光纤41的一个端面的状态下安装到设备主体31 固定在测量探针40的前端面40a上，另一端面与设备内光纤32的端面抵接。（C）2005年，JPO＆NCIPI

8. 发明专利

JP2004298547A Glucose concentration measuring apparatus 审中-公开
标题翻译：葡萄糖浓度测量仪器
公开(公告)号：JP2004298547A
公开(公告)日：2004-10-28
申请号：JP2003098033
申请日：2003-04-01
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： KANEKO MAMORU , SASAI TSUGUHISA , HIEDA MASAYA , NAKANO TAKUYA , SATO KOHEI , ARIFUKU KIYOSHI
IPC分类号： G01N21/35 , A61B5/117 , A61B5/145 , A61B5/1455 , G01N21/3577 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To provide a glucose concentration measuring apparatus which is non-invasive along with high measuring precision. SOLUTION: The apparatus is provided with a light irradiation part 10, a detection part 20, an arithmetic part 30, a display part 40 and a measuring part 50. A protrusion 51, which lets the inner surface of the finger tip F be pressed to contact it, is provided at the measuring part 50 to accomplish the non-invasive measurement. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供具有高测量精度的非侵入性的葡萄糖浓度测量装置。解决方案：该设备设置有光照射部分10，检测部分20，运算部分30，显示部分40和测量部分50.突起51，其使指尖F的内表面被设置在测量部件50上以实现非侵入式测量。版权所有（C）2005，JPO＆NCIPI

9. 发明专利

JP2004290226A Glucose concentration measuring apparatus 审中-公开
公开(公告)号：JP2004290226A
公开(公告)日：2004-10-21
申请号：JP2003082769
申请日：2003-03-25
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： KANEKO MAMORU , YOSHIDA KAZUHIRO , ONO WATARU , SASAI TSUGUHISA , UEHARA YASUHIRO , IMAI HIDENOBU , ARIFUKU KIYOSHI , HIEDA MASAYA , SATO KOHEI , NAKANO TAKUYA
IPC分类号： G01N21/35 , A61B5/145 , A61B5/1455 , G01N21/359
摘要： PROBLEM TO BE SOLVED: To provide a glucose concentration measuring apparatus which is not invasive along with a higher measuring accuracy. SOLUTION: Herein employed are an optical fiber 5 which is disposed on the surface S1 of a living body to irradiate inside the living body S with far infrared rays L1, a PbS sensor 6 which detects the rays L2 diffused into the living body S or passing therethrough outside the living body S, an arithmetic part 18 which determines the concentration of glucose in the living body S based on the received signals detected by the PbS sensor 6 and a pump 20 which applies a negative pressure to the surface S1 of the living body. COPYRIGHT: (C)2005,JPO&NCIPI

10. 发明专利

JP2004286475A Apparatus for measuring glucose concentration 审中-公开
公开(公告)号：JP2004286475A
公开(公告)日：2004-10-14
申请号：JP2003076059
申请日：2003-03-19
申请人： Biox Kk , Olympus Corp , オリンパス株式会社 , バイオックス株式会社
发明人： KANEKO MAMORU , YOSHIDA KAZUHIRO , ONO WATARU , SASAI TSUGUHISA , UEHARA YASUHIRO , HAMANO MASAHIKO , AOKI ISAO , IMAI HIDENOBU , ARIFUKU KIYOSHI , HIEDA MASAYA , SATO KOHEI , NAKANO TAKUYA
IPC分类号： G01N21/35 , A61B5/145 , A61B5/1455 , G01N21/3577 , G01N21/359 , G01N21/49
摘要： PROBLEM TO BE SOLVED: To improve measurement accuracy by increasing S/N ratios of an apparatus for noninvasively measuring glucose concentrations. SOLUTION: The apparatus for measuring the glucose concentrations is provided with a light emitting section 14 which is disposed on a surface of a living body and irradiates the inside of the living body with near-infrared light, a light receiving aperture section 12 wherein a detector 13 detecting light at the outside of the living body, which diffuses in or passes through the living body, is disposed, and a calculating device 29 which obtains the glucose concentration in the living body based on received light signals detected by the detector 13. In the apparatus, a plurality of light emitting sections 14 are arranged in the circumferential direction on the periphery of the light receiving aperture section 12, and optical axes of the light emitting sections 14 are set sideling in relation to the center axis of the detector 13 so that the optical axes intersect with each other at the center axis of the detector 13. COPYRIGHT: (C)2005,JPO&NCIPI

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