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    • 1. 发明专利
    • Concentration measuring instrument
    • 浓度测量仪器
    • JP2007085974A
    • 2007-04-05
    • JP2005277355
    • 2005-09-26
    • Citizen Watch Co Ltdシチズン時計株式会社
    • SUGIURA YOSHIHARUYANO TAKAKAZUFUKUDA MASAHIRO
    • G01N21/21G01J4/04G01N21/11G01N21/15G01N33/493
    • PROBLEM TO BE SOLVED: To solve the problem wherein continuous monitoring of the degree of optical activity of the sample coming out of a filter after measuring inhibiting components in the sample is removed by the filter is useful to sense a steady state in the measurement of concentration for measuring the concentration of an optically active substance in the sample, by measuring the degree of the optical rotation of the sample but the concentration value of the sample easy to change, even if a steady state is obtained because continuously flowing sample is measured. SOLUTION: When it is sensed that the degree of optical activity becomes the steady state, feeding of a liquid is stopped for a fixed time, and the degree of optical activity of the sample in a stoppage state is measured again. As a result, the concentration of sugar in urine can be measured with high accuracy. COPYRIGHT: (C)2007,JPO&INPIT
    • 解决的问题为了解决在通过滤波器去除样品中的抑制成分被测量之后,从滤波器出来的样品的光活度的连续监测被用于在 通过测量样品的旋光度,但样品的浓度值容易变化来测量样品中光学活性物质的浓度的浓度测量,即使获得稳定状态,因为连续流动的样品是 测量。 解决方案:当检测到光学活度变为稳定状态时,液体的供给停止一定时间,并且再次测量样品在停止状态下的光学活动程度。 结果,可以高精度地测量尿中的糖浓度。 版权所有(C)2007,JPO&INPIT
    • 2. 发明专利
    • Concentration measuring device
    • 浓度测量装置
    • JP2006275863A
    • 2006-10-12
    • JP2005097300
    • 2005-03-30
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUDA MASAHIROYANO TAKAKAZUMATSUMOTO KENJISUGIURA YOSHIHARU
    • G01N21/21G01N33/493
    • G01N21/5907G01N21/21
    • PROBLEM TO BE SOLVED: To solve the problems wherein, when trying acquisition of optical rotation in a wide range, accuracy is lowered, and on the contrary, when trying improvement of the accuracy, the range of the measurable optical rotation is narrowed, since the accuracy is lowered in proportion to largeness of a modulation width when using a method for modulating the optical rotation, in the case where the optical rotation by a rotatory material in a sample is measured.
      SOLUTION: In this concentration measuring device for measuring the concentration of the rotatory material in the sample by measuring the optical rotation by the rotatory material in the sample, when calculating the concentration of the rotatory material in the sample from a light intensity signal after passing of the sample in a photodetector when the optical rotation of linearly polarized light entering the sample is modulated by an optical rotation modulation means, a modulation range of the optical rotation of the linearly polarized light by the optical rotation modulation means is changed, based on a detection signal by the photodetector, and a detection signal capable of calculating the concentration is acquired, and thereby highly-accurate concentration measurement becomes possible regardless of the intensity of the concentration in the sample.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 要解决的问题为了解决当尝试在宽范围内获得光学旋转时精度降低的问题,相反,当尝试提高精度时,可测量的旋光范围变窄 由于在使用调制光学旋转的方法时,在测定样品中的旋转材料的旋光度的情况下,精度与调制宽度的大小成比例地降低。 解决方案:在这种浓度测量装置中,通过测量样品中的旋转材料的旋光度来测量样品中的旋转材料的浓度,当从光强度信号计算样品中的旋转材料的浓度时 当通过光旋转调制装置调制进入样品的线偏振光的旋光度时,在光电检测器中通过样品之后,基于旋转调制装置的线偏振光的旋转的调制范围基于 通过光电检测器检测信号,并且获得能够计算浓度的检测信号,由此可以高精度地进行浓度测量,而与样品中的浓度强度无关。 版权所有(C)2007,JPO&INPIT
    • 3. 发明专利
    • Optical measuring instrument
    • 光学测量仪器
    • JP2005283313A
    • 2005-10-13
    • JP2004097308
    • 2004-03-30
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUSHIMA MIZUEYANO TAKAKAZUMATSUMOTO KENJIFUKUDA MASAHIRO
    • G01N21/03G01N21/15G01N21/21
    • PROBLEM TO BE SOLVED: To provide an optical measuring instrument having a pretreatment method capable of eliminating easily an inhibition influence of ascorbic acid in measurement of a glucose concentration by a rotation angle measuring system.
      SOLUTION: A plurality of electrodes is provided in a place not disturbing an optical path, in a sample container of the optical measuring instrument, a voltage is applied to the electrodes to oxidize a measurement inhibitor bringing an inhibition factor in the measurement, an optical characteristic is measured thereafter, and the influence due to the inhibitor in the measurement is thereby eliminated to measure accurately the optical characteristic of a measuring objective substance.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 解决问题:提供一种具有能够通过旋转角度测量系统容易地消除抗坏血酸在葡萄糖浓度测定中的抑制作用的预处理方法的光学测量仪器。 解决方案:在不影响光路的位置设置多个电极,在光学测量仪器的样品容器中,向电极施加电压以氧化测量抑制剂,从而产生测量中的抑制因子, 此后测量光学特性,由此消除由于抑制剂在测量中的影响,以准确地测量测量目标物质的光学特性。 版权所有(C)2006,JPO&NCIPI
    • 4. 发明专利
    • Device for measuring refractive index, and concentration measuring device
    • 用于测量折射率的装置和浓度测量装置
    • JP2005148027A
    • 2005-06-09
    • JP2003390177
    • 2003-11-20
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUDA MASAHIROYANO TAKAKAZUMATSUMOTO KENJI
    • G01N21/45
    • PROBLEM TO BE SOLVED: To solve the problems in optical measurement by a conventional low coherence interference method, wherein adjustment of equipment needing extremely high precision is required, because of the need for mechanical operations, and the mechanical operation of moving a stage seriously affects on measuring precision, whereas as a means for measuring the concentration of a sample or the thickness of a transparent thin film, determination of its refractive index by the low-coherence interference method or the like is performed.
      SOLUTION: The mechanical operation is replaced by an electrical operation, such as light modulation by a liquid crystal element, whereby the adjustment of equipment requiring very high precision is dispensed with, and precise measurement can be performed, since the influence of vibration or the like can be eliminated. Although the arrangement of equipment has seriously been limited in the past, because a mirror is made movable to use the reflected light by the mirror as the reference light, the liquid crystal element enabling the use of transmitted light is adapted, whereby a device configuration responding to various states, such as miniaturization, can be attained.
      COPYRIGHT: (C)2005,JPO&NCIPI
    • 要解决的问题:为了通过传统的低相干干涉法解决光学测量中的问题,需要极高精度的设备的调整,因为需要机械操作和移动台阶的机械操作 严重影响测量精度,而作为测量样品浓度或透明薄膜厚度的手段,通过低相干干涉法等来确定其折射率。 解决方案:机械操作由诸如液晶元件的光调制的电气操作代替,由此不需要非常高精度的设备的调节,并且可以进行精确的测量,因为振动的影响 等等。 尽管设备的布置在过去严重受到限制,但是由于镜子被制成可移动以使用反射镜作为参考光,所以可以使用能够使用透射光的液晶元件,从而响应于设备配置 能够实现小型化等各种状态。 版权所有(C)2005,JPO&NCIPI
    • 5. 发明专利
    • Concentration measurement device and concentration measurement method
    • 浓度测量装置和浓度测量方法
    • JP2004077466A
    • 2004-03-11
    • JP2003149021
    • 2003-05-27
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUDA MASAHIROYANO TAKAKAZUMATSUMOTO KENJI
    • A61B5/00A61B5/145A61B5/1455G01N21/21
    • A61B5/14558A61B5/6826A61B5/6838G01N21/21
    • PROBLEM TO BE SOLVED: To increase the accuracy of concentration measurement of an optically active substance included in a pulsating component in a specimen. SOLUTION: A concentration measurement device 1 is provided with a linearly polarized light output part 10 for outputting linearly polarized light Lb, a rotation angle modulation part 13 for modulating the angle of rotation of the linearly polarized light Lb output from the linearly polarized light output part 10, a luminous intensity detection part 15 for detecting the intensity of transmitted light Ld transmitted across a specimen 100 after optical rotation by an optically active substance in the specimen 100 when the linearly polarized light Lb whose angle of rotation is modulated by the rotation angle modulation part 13 is emitted to the speciment 100, a displacement calculation part for calculating a displacement of the angle of rotation of the transmitted light Ld displaced by pulsation of a pulsating component, according to the angle of rotation modulated by the rotation angle modulation part 13 and the intensity of the transmitted light Ld detected by the luminous intensity detection part 15, and a concentration calculation part for calculating the concentration of the optically active substance included in the pulsating component in the specimen 100, according to the displacement calculated by the displacement calculation part. COPYRIGHT: (C)2004,JPO
    • 要解决的问题:提高试样中脉动成分中所含的光学活性物质的浓度测定精度。 解决方案:浓度测量装置1设置有用于输出线性偏振光Lb的直线偏振光输出部10,用于调制从线性偏振光Lb输出的线偏振光Lb的旋转角度的旋转角度调制部13 光输出部10,发光强度检测部15,用于检测当通过旋转角调制的线偏振光Lb被调制在样本100中时,通过被检体100中的光学活性物质旋光后的样本100透过的透射光Ld的强度 旋转角调制部13被发射到形状100,位移计算部,用于根据由旋转角度调制调制的旋转角度来计算由脉动分量的脉动而偏移的透射光Ld的旋转角度的位移 部分13和由发光强度d检测的透射光Ld的强度 检测部15,以及根据由位移计算部算出的位移来计算试样100中的脉动成分中含有的光学活性物质的浓度的浓度计算部。 版权所有(C)2004,JPO
    • 7. 发明专利
    • Concentration measuring device
    • 浓度测量装置
    • JP2006275582A
    • 2006-10-12
    • JP2005091342
    • 2005-03-28
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUDA MASAHIROYANO TAKAKAZUSUGIURA YOSHIHARU
    • G01N21/21G01N33/483G01N33/493
    • PROBLEM TO BE SOLVED: To solve the problem wherein, in the case where the concentration of a rotatory material in a sample is measured by measuring optical rotation of the sample, especially in the case where the glucose concentration in urine is measured, when various measurement inhibition components included in urine are removed by using resins, high-rate recovery of glucose is difficult because the glucose is sandwiched physically between the resins by merely allowing the urine to pass the resins.
      SOLUTION: After allowing the urine to pass a column filled with the resins, cleaning water such as pure water is allowed again to pass the same column, to thereby recover the glucose unrecovered at the urine passing time. In this case, since the measurement inhibition component is hardly included in the sample after passing, the glucose concentration in the original urine can be measured highly accurately without being influenced by the measurement inhibition component by measuring the optical rotation of the sample after passing.
      COPYRIGHT: (C)2007,JPO&INPIT
    • 解决的问题为了解决在通过测定样品的旋光度来测定样品中的旋转物质的浓度的情况下,特别是在测定尿中的葡萄糖浓度的情况下, 当通过使用树脂除去包含在尿液中的各种测量抑制成分时,难以高速回收葡萄糖,因为通过仅使尿液通过树脂,将葡萄糖物理地夹在树脂之间。

      解决方案:使尿液通过填充有树脂的柱后,再次允许清洗水如纯水通过相同的柱,从而回收在尿液通过时未回收的葡萄糖。 在这种情况下,由于测定抑制成分在通过后几乎不包含在样品中,因此通过测量经过后的样品的旋光度,可以高精度地测量原始尿液中的葡萄糖浓度,而不受测定抑制成分的影响。 版权所有(C)2007,JPO&INPIT

    • 8. 发明专利
    • Imaging lens device
    • 成像镜头装置
    • JP2006251613A
    • 2006-09-21
    • JP2005070592
    • 2005-03-14
    • Citizen Watch Co Ltdシチズン時計株式会社
    • MATSUMOTO KENJIYANO TAKAKAZUFUKUDA MASAHIRO
    • G02F1/13G02B3/00
    • PROBLEM TO BE SOLVED: To provide an imaging lens device equipped with a liquid crystal lens which has sufficient lens power even when the response speed of a liquid crystal lens is made sufficiently fast, and which is made small-sized and thin.
      SOLUTION: The imaging lens device which has a lens system and an imaging element picking up an optical image formed through the lens system employs constitution in which a lens system has a liquid crystal lens array formed by arranging a plurality of unit lenses in plane. This lens system comprises a plurality of lens arrays, and at least one of the plurality of lens arrays is preferably a liquid crystal lens array.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:即使当液晶透镜的响应速度足够快时,也提供具有足够透镜能力的液晶透镜的成像透镜装置,并且被制成小型和薄型。 解决方案:具有透镜系统和拾取通过透镜系统形成的光学图像的成像元件的成像透镜装置采用其中透镜系统具有通过将多个单位透镜布置形成的液晶透镜阵列的结构 平面。 该透镜系统包括多个透镜阵列,并且多个透镜阵列中的至少一个优选为液晶透镜阵列。 版权所有(C)2006,JPO&NCIPI
    • 9. 发明专利
    • Device for measuring urine component
    • 用于测量尿素组分的装置
    • JP2006090931A
    • 2006-04-06
    • JP2004278935
    • 2004-09-27
    • Citizen Watch Co Ltdシチズン時計株式会社
    • YANO TAKAKAZUMATSUMOTO KENJIFUKUDA MASAHIROSUGIURA YOSHIHARU
    • G01N33/493
    • PROBLEM TO BE SOLVED: To provide a structure of a maintenance free device for measuring urine component having no replacing part due to contamination by measuring the concentration of glucose having no error with high precision even in urine containing an inhibitor such as amino acid or the like and reducing the contamination in a conduit and the measuring device due to a urine component.
      SOLUTION: The contamination in conduits 5 and 63 or the contamination in a measuring container 55 can be reduced by measuring a urine sugar measuring component by providing a component removing means 3 between a urine sampling part 1 and the conduit 5. Further, the efficient reduction of contamination becomes possible by controlling the passing time of the component removing means 3 by controlling a valve 2. By this constitution, since maintenance work can be reduced and a measuring error can be reduced, highly precise measurement becomes possible. This measuring device is especially effective from an aspect for holding light transmissivity in an optical measuring system such as an optical rotation measuring system or a light absorption measuring system.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 解决的问题:提供一种免维护装置的结构,即,即使在含有氨基酸等抑制剂的尿液中,也可以通过高精度地测定没有误差的葡萄糖浓度而由于污染而不含有替换部的尿液成分 并且由于尿液成分而减少导管和测量装置中的污染。 解决方案:通过在尿液采样部分1和导管5之间设置一个成分去除装置3,可以测量尿糖测量部件,从而可以减少导管5和63中的污染物或测量容器55中的污染。另外, 通过控制阀2来控制部件去除装置3的通过时间,可以有效地减少污染。通过这种结构,由于可以减少维护工作并且可以降低测量误差,因此可以进行高精度的测量。 该测量装置在光学测量系统或光吸收测量系统等光学测量系统中保持透光性的方面特别有效。 版权所有(C)2006,JPO&NCIPI
    • 10. 发明专利
    • Concentration measuring device
    • 浓度测量装置
    • JP2006090930A
    • 2006-04-06
    • JP2004278934
    • 2004-09-27
    • Citizen Watch Co Ltdシチズン時計株式会社
    • FUKUDA MASAHIROYANO TAKAKAZUMATSUMOTO KENJISUGIURA YOSHIHARU
    • G01N21/21G01N21/59G01N33/493
    • PROBLEM TO BE SOLVED: To provide a concentration measuring device capable of measuring highly accurately the glucose concentration in urine even in the case of urine including an inhibitor such as an amino acid.
      SOLUTION: In this concentration measuring device, urine is irradiated with linearly polarized light, and the optical rotation of the urine is measured, to thereby measure the glucose concentration in the urine. The device has a means for measuring the optical rotation of the urine and a means for measuring a transmissivity through the urine, and measures the amount of a rotatory component other than glucose in the urine from the transmissivity through the urine, and corrects the glucose concentration in the urine by the amount of the rotatory component other than glucose in the urine.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:提供即使在包括诸如氨基酸的抑制剂的尿的情况下也能够高精度地测量尿中的葡萄糖浓度的浓度测量装置。 解决方案:在该浓度测定装置中,用线偏振光照射尿液,测定尿液的旋光度,测定尿液中的葡萄糖浓度。 该装置具有用于测量尿液的旋光度的装置和用于测量通过尿液的透射率的装置,并且通过尿液的透射率测量尿液中葡萄糖以外的旋转成分的量,并校正葡萄糖浓度 在尿液中除了尿液中的葡萄糖以外的旋转成分的量。 版权所有(C)2006,JPO&NCIPI