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1. 发明专利

JP2008145125A Biochemical reaction cartridge and biochemical treatment device system 有权
标题翻译：生化反应盒和生化处理装置系统
公开(公告)号：JP2008145125A
公开(公告)日：2008-06-26
申请号：JP2006329371
申请日：2006-12-06
申请人： Canon Inc , キヤノン株式会社
发明人： HOSOI NOBUYUKI
IPC分类号： G01N35/08 , C12M1/00 , C12M1/34 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a biochemical reaction cartridge free from contamination in detection.
SOLUTION: The present invention discloses the biochemical reaction cartridge provided with a detachable cartridge protection means, to be used with separated when introduced into a device, and a biochemical treatment system provided therewith.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供在检测中没有污染的生化反应盒。解决方案：本发明公开了一种生物化学反应盒，其具有可拆卸的盒保护装置，当被引入装置时被分离使用，以及与其一起提供的生物化学处理系统。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2005172804A Probe-fixing substrate, detection device and method for discriminating change in the probe-fixing substrate 有权
标题翻译：探针固定基板，检测装置和用于在探针固定基板中识别变化的方法
公开(公告)号：JP2005172804A
公开(公告)日：2005-06-30
申请号：JP2004326785
申请日：2004-11-10
申请人： Canon Inc , キヤノン株式会社
发明人： ISHIBASHI TORU , KAWAMURA MASASHI , HOSOI NOBUYUKI
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/566 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To enable degree of probe degradation or the degree of the change in a protector to be discriminated, by mounting an element which discriminates the presence or the absence of factors contributing to the probe degradation or factors contributing to the changes in the protector, on a solid phase probe array or the like, and by reading changes in the element. SOLUTION: The probe-fixing substrate which is a probe-fixing substrate where a probe capable of specifically bonding to a target substance is fixed on the substrate, further includes an element which detects an environmental change being a contributing factor of the change in the probe-fixing substrate. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了使得探测器劣化程度或保护器的变化程度被识别，通过安装鉴别有助于探针降解的因素的存在或不存在的元素或对保护器上的变化，固相探针阵列等，以及读取元件中的变化。解决方案：作为探针固定基板的探针固定基板，其中能够特异性地结合到目标物质的探针固定在基板上，还包括检测环境变化的因素是变化的因素在探针固定基板中。版权所有（C）2005，JPO＆NCIPI

3. 发明专利

JP2003321220A Method for producing alumina hydrate for coating solution 审中-公开
标题翻译：生产用于涂料溶液的氢氧化铝的方法
公开(公告)号：JP2003321220A
公开(公告)日：2003-11-11
申请号：JP2002128601
申请日：2002-04-30
申请人： Canon Inc , キヤノン株式会社
发明人： ASAOKA MASANOBU , HOSOI NOBUYUKI
IPC分类号： C01F7/02 , C09C1/40 , C09C3/04 , C09D7/12 , C09D201/00
摘要： PROBLEM TO BE SOLVED: To obtain an alumina hydrate for a coating solution having a low viscosity even in high concentration.
SOLUTION: The step for producing the alumina hydrate for the coating solution comprises concentrating an alumina hydrate sol under the conditions that the alumina hydrate sol is in contact with stainless steel in a container used for the concentration.
COPYRIGHT: (C)2004,JPO
摘要翻译：待解决的问题：为了获得即使高浓度也具有低粘度的涂布溶液的氧化铝水合物。解决方案：用于制备用于涂布溶液的氧化铝水合物的步骤包括在氧化铝水合物溶胶与用于浓缩的容器中与不锈钢接触的条件下浓缩水合氧化铝溶胶。版权所有（C）2004，JPO

4. 发明专利

JP2006149337A Probe carrier, method for producing the same and method for preserving the same 审中-公开
标题翻译：探针载体，其制备方法及其保存方法
公开(公告)号：JP2006149337A
公开(公告)日：2006-06-15
申请号：JP2004348932
申请日：2004-12-01
申请人： Canon Inc , キヤノン株式会社
发明人： HOSOI NOBUYUKI , ISHIBASHI TORU , KAWAMURA MASASHI
IPC分类号： C12M1/00 , C12N15/09 , G01N33/53
摘要： PROBLEM TO BE SOLVED: To provide a probe carrier which inhibits the temporal deterioration of a function for binding to a target substance, can surely detect and separate the target substance, prevents the deterioration of the probe even after stored for a long period, and has a long life, and to provide a method for producing the same.
SOLUTION: This probe carrier in which a probe for detecting a target substance is immobilized on a support is characterized by containing a rosin in the probe-immobilized region on the support. The probe carrier in which a probe for detecting a target substance is immobilized on a support is characterized by containing a resin acid and/or its analogue in the probe-immobilized region on the support. The resin acid is preferably an abietic acid compound such as abietic acid or a dehydroabietic acid compound.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供抑制与目标物质结合的功能的颞下降的探针载体，可以可靠地检测和分离目标物质，即使在长时间保存后也能防止探针的劣化并且具有长的使用寿命，并提供其制造方法。解决方案：将其中用于检测目标物质的探针固定在载体上的探针载体的特征在于在载体上的探针固定化区域中含有松香。其中用于检测目标物质的探针固定在载体上的探针载体的特征在于在载体上的探针固定化区域中含有树脂酸和/或其类似物。树脂酸优选为松香酸化合物，例如松香酸或脱氢松香酸化合物。版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2005315785A Probe fixing carrier and its manufacturing method 有权
标题翻译：探头固定架及其制造方法
公开(公告)号：JP2005315785A
公开(公告)日：2005-11-10
申请号：JP2004135850
申请日：2004-04-30
申请人： Canon Inc , キヤノン株式会社
发明人： HOSOI NOBUYUKI , ISHIBASHI TORU , KAWAMURA MASASHI
IPC分类号： G01N33/53 , C12N15/09 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To improve the storage lifetime of a probe carrier.
SOLUTION: Polyvinyl alcohol having a degree of polymerization of 2,000 or smaller and a saponification value of 85% or higher is contained in at least a probe fixing carrier in which a probe is fixed to a prescribed part on a base.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提高探针载体的存储寿命。解决方案：至少将探针固定在基底上的规定部位的探针固定载体中，含有聚合度为2,000以下，皂化值为85％以上的聚乙烯醇。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2006170832A Probe carrier and probe medium and method for manufacturing the same 有权
标题翻译：探测载体和探测介质及其制造方法
公开(公告)号：JP2006170832A
公开(公告)日：2006-06-29
申请号：JP2004364313
申请日：2004-12-16
申请人： Canon Inc , キヤノン株式会社
发明人： ISHIBASHI TORU , HOSOI NOBUYUKI , KAWAMURA MASASHI
IPC分类号： G01N33/547 , C12M1/00 , C12M1/34 , C12N15/09 , G01N33/53 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To acquire a probe carrier capable of detection without the need for special treatments even immediately after a probe has been suppressed from becoming dry and stored for a long period of time after its manufacture, stably holding the function of specifically binding to a target substance, and achieving a long life.
SOLUTION: In the probe carrier comprising the probe which specifically binds to the target substance and a carrier carrying the probe, the probe is coated with a coating material containing a nonvolatile water-soluble monomer and/or a nonvolatile water-soluble oligomer. It is preferable that the water-soluble monomer contained in the coating material is a tetrose; a pentose; a hexose; a heptose; or cyclitols in which a hydroxyl group may be protected by a protective group and n-saccharides (wherein, 2≤n≤10). The probe and the target substance are an oligonucleotide, a polynucleotide, a protein, or a sugar chain.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：即使在探针被抑制干燥并且在其制造之后长时间储存之后即使立即获得能够检测的探针载体，也不需要特殊处理，因此稳定地保持其功能特异性地结合目标物质，达到长寿命。解决方案：在包含特异性结合目标物质的探针的探针载体和携带探针的载体中，探针涂覆有含有不挥发性水溶性单体和/或非挥发性水溶性低聚物的涂层材料。包含在涂料中的水溶性单体优选为四氢呋喃; 戊糖己糖一只肝或其中羟基可被保护基保护的环状醇和n-糖（其中，2≤n≤10）。探针和靶物质是寡核苷酸，多核苷酸，蛋白质或糖链。版权所有（C）2006，JPO＆NCIPI

7. 发明专利

JP2007155585A Biochemical reaction cartridge, cover member and probe carrier with reaction chamber 审中-公开
标题翻译：生物化学反应盒，盖子和反应室的探针载体
公开(公告)号：JP2007155585A
公开(公告)日：2007-06-21
申请号：JP2005353369
申请日：2005-12-07
申请人： Canon Inc , キヤノン株式会社
发明人： HOSOI NOBUYUKI
IPC分类号： G01N33/53 , C12M1/00 , G01N33/552 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a biochemical reaction cartridge having a structure enhanced in the degree of freedom in the planning of a chamber part by functionally separating a reaction chamber part and a handling mechanism.
SOLUTION: The biochemical reaction cartridge is constituted by at least fitting a cartridge, which houses a solution used for the biochemical treatment of a specimen, to the reaction chamber in which a probe carrier is mounted. The cartridge has a first injection part for injecting the solution, a first discharge hole for receiving the solution discharged from the chamber and a placing part on which the reaction chamber having the probe carrier place thereon is placed. The reaction chamber is constituted by forming a reaction space, where the solution is reacted with the probe supported on the probe carrier by placing the probe carrier on the reaction chamber and the first injection port and the first discharge port are connected to each other.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：通过在功能上分离反应室部分和处理机构来提供具有增强室部分规划自由度的结构的生化反应盒。解决方案：生化反应盒至少将容纳用于生物化学处理样品的溶液的盒装配到安装有探针载体的反应室中。该盒具有用于注入溶液的第一注射部分，用于接收从腔室排出的溶液的第一排放孔和放置有其上具有探针载体的反应室的放置部件。反应室通过形成反应空间构成，其中溶液与支撑在探针载体上的探针反应，将探针载体放置在反应室上，并且第一注入口和第一排出口彼此连接。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JPS6176571A Production of magnetic coating 失效
标题翻译：生产磁性涂料
公开(公告)号：JPS6176571A
公开(公告)日：1986-04-19
申请号：JP19843984
申请日：1984-09-25
申请人： Canon Inc
发明人： HOSOI NOBUYUKI , YOSHIDA YUTAKA
IPC分类号： C09D5/23 , B01J13/00 , B02C17/16
摘要： PURPOSE: A medium which has 2 or more peaks in particle size distribution is used to mix the starting materials for magnetic coatings in a sand mill to improve the dispersibility over the conventional level.
CONSTITUTION: A medium which has 2 or more peaks in particle size distribution (the difference of individual peak values is preferably larger than 0.7mm) or a medium having 2 or more different densities (preferably the difference between average values is larger than 3g/cm
2 ) is used to mix the starting materials for magnetic coating with a sand mill.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：将具有2个或更多个粒度分布峰的介质用于在砂磨机中混合磁性涂层的起始材料，以提高在常规水平上的分散性。构成：具有2个以上的粒度分布峰（各个峰值的差优选大于0.7mm）或具有2个以上不同密度的介质（优选平均值之差大于3g / cm 2）的介质 <2>）用于将用于磁性涂层的起始材料与砂磨机混合。

9. 发明专利

JPS6176558A Magnetic coating 失效
标题翻译：磁性涂料
公开(公告)号：JPS6176558A
公开(公告)日：1986-04-19
申请号：JP19844284
申请日：1984-09-25
申请人： Canon Inc
发明人： HOSOI NOBUYUKI , YOSHIDA YUTAKA , HASHIMOTO SHIGERU
IPC分类号： C09D5/23 , C08L1/00 , C08L27/00 , C08L27/06 , C08L75/00 , C08L75/04 , C09D127/04 , C09D175/00
摘要： PURPOSE: The titled coating that contains, as a binder, a plurality of copolymers with specific polymerization degrees and a polyurethane resins, thus being suitable for use is magnetic recording media, because it has good electromagnetic transduction properties, coating film properties and gives nontacky magnetic layers.
CONSTITUTION: (A) A vinyl chloride-vinyl acetate-vinyl alcohol terpolymer of (i) less than 300 average polymerization degree and of (ii) more than 400 polymerization degree is kneaded with (B) a polyurethane resin to give the objective coating. At first, the desired magnetic powder and a dispersant are sufficiently kneaded with component i, then component ii is added in two steps, further component B is added, and they are stirred.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：作为粘合剂的具有特定聚合度的多种共聚物和聚氨酯树脂，因此适用的标题涂料是磁记录介质，因为它具有良好的电磁转导性能，涂膜性能，并提供非磁性磁性层。（A）将（i）平均聚合度低于300的聚氯乙烯 - 乙酸乙烯酯 - 乙烯醇三元共聚物和（ii）聚合度大于400的混合物与（B）聚氨酯树脂混合，得到目标涂层。首先，将所需的磁性粉末和分散剂与组分i充分捏合，然后分两步加入组分ii，再加入组分B，并搅拌它们。

10. 发明专利

JPS60195729A Magnetic recording medium 失效
标题翻译：磁记录介质
公开(公告)号：JPS60195729A
公开(公告)日：1985-10-04
申请号：JP5020284
申请日：1984-03-17
申请人： Canon Inc
发明人： HOSOI NOBUYUKI , KOUZUKI SUSUMU , YOSHIDA YUTAKA , HASHIMOTO SHIGERU
IPC分类号： G11B5/708 , C09D5/23 , C09D7/12 , C10M105/74 , C10N10/12
摘要： PURPOSE: To improve particularly the sliding characteristic of a magnetic layer among other physical characteristics and to obtain the titled coating-type magnetic recording medium by incorporating a specified organic molybdenum compd. into a magnetic layer obtained by dispersing ferromagnetic power in a binder.
CONSTITUTION: A magnetic paint is obtained by dissolving molybdenum dialkyl dithiophosphate shown by the formula (R is 1W20C alkyl), mixing ferromagnetic metallic powder or the powder of a ferromagnetic metallic oxide, etc. into said soln., and adding, if necessary, the particles of an abrasive such as Al
2 O
3 , Cr
2 O
3 , and SiC having ≥5Mohs hardness. The paint is coated on a nonmagnetic body which is oriented, dried, and then calendered to form a magnetic layer having a smooth surface. The magnetic powder can also be pretreated in a soln. of the organic molybdenum compd., filtered, dried, and then dispersed in the soln. of the binder. The organic molybdenum compd. is strongly adsorbed by the ferromagnetic powder and the abrasive due to the presence of S in the organic molybdenum compd. in this way, and the sliding characteristic is particularly improved. The baking on a magnetic head is also prevented, and the magnetic medium having excellent characteristics such as stillness at low temps. is obtained.
COPYRIGHT: (C)1985,JPO&Japio
摘要翻译：目的：特别提高磁性层的其他物理特性的滑动特性，并通过掺入特定的有机钼化合物获得标题涂覆型磁记录介质。转化成通过将铁磁力分散在粘合剂中而获得的磁性层。构成：通过将式（R为1-20C烷基）表示的二烷基二硫代磷酸钼，铁磁金属粉末或铁磁性金属氧化物粉末等混合到所述溶胶中，得到磁性涂料，并且如有必要加入，磨料的颗粒如Al2O3，Cr2O3和具有> = 5Mohs硬度的SiC。将涂料涂覆在非磁性体上，其取向，干燥，然后压延以形成具有光滑表面的磁性层。磁粉也可以在溶胶中进行预处理。的有机钼化合物，过滤，干燥，然后分散在溶胶中。的粘合剂。有机钼化合物由于在有机钼化合物中存在S，强磁性粉末和研磨剂被强烈吸附。以这种方式，并且特别地提高了滑动特性。也可以防止在磁头上的烘烤，并且磁性介质具有优异的特性，例如在低温下的静止。获得。

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