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    • 1. 发明专利
    • BIOLOGICAL REACTION
    • JPS6251996A
    • 1987-03-06
    • JP18985085
    • 1985-08-30
    • CHIYODA CHEM ENG CONSTRUCT CO
    • YUSHINA YOSHINORIKAMATA HIROSHISATO HIROKI
    • C12P1/00C02F3/06C02F3/10C12M1/00
    • PURPOSE:To make it possible to efficiently separate a reaction product substance, by sterically entangling fine wiry materials consisting of a microbial carrier, binding at least part of mutual contact parts of the wiry materials and using the resultant wiry materials for a bioreactor. CONSTITUTION:A biological reaction substrate is introduced into a reaction tank filled with a microbial carrier and microorganisms to carry out microbial reaction and take out the biological reaction product. In the process, the microbial carrier is constituted of fine wiry materials obtained by sterically entangling the materials and binding at least part of the mutual contact parts thereof and having complicated space are used to keep the microbial carrier and the microorganisms in an immobilized state. The reaction tank is divided into many stages by effective partition plates, and the microbial carrier having a large particle diameter is filled in the first stage. The microbial carrier is filled in the respective stages so that the particle diameter in the stages may vary with the stages one after another decreasing toward the final stage.