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    • 1. 发明专利
    • Th1 INDUCER AND METHOD FOR PRODUCING THE SAME
    • Th1电感器及其制造方法
    • JP2013147458A
    • 2013-08-01
    • JP2012009119
    • 2012-01-19
    • Bio Ken:Kk有限会社バイオ研Shoyaku Hakko Kenkyusho:Kk有限会社 生薬発酵研究所Arimento Kogyo Kkアリメント工業株式会社
    • SUGA TATSUHIKOKATSURA YOSHIYUKITAGUCHI KUNIAKIOGASAWARA TOMOHIKO
    • A61K36/06A61K9/14A61P37/04
    • PROBLEM TO BE SOLVED: To provide a Th1 inducer having an excellent effect of inducing the hyperergasia of Th1 using yeast as raw material, and to provide a method for producing the Th1 inducer.SOLUTION: A one obtained by micronizing the cell body of yeast and controlling the median diameter (D50) of the volume integrated particle size distribution thereof to 1 to 10 μm is used as the active ingredient of a Th1 inducer. In the method for producing the Th1 inducer, preferably, a dispersant is added to the cell body of yeast, and this is subjected to wet dispersion treatment, is micronized till the median diameter (D50) of the volume integrated particle size distribution of the cell body reaches 1 to 10 μm, and is next powdered, or the cell body of yeast is subjected to wet dispersion treatment and is micronized till the median diameter (D50) of the volume integrated particle size distribution of the cell body reaches 1 to 10 μm, a dispersant is added thereto, and powdering is performed.
    • 要解决的问题:提供一种Th1诱导剂,其具有以酵母作为原料诱导Th1的高血压发生的优异效果,提供Th1诱导剂的制造方法。溶液:将酵母的细胞体微粉化, 将其体积积分粒径分布的中值粒径(D50)控制在1〜10μm作为Th1诱导剂的有效成分。 在制造Th1诱导剂的方法中,优选在酵母的细胞体中添加分散剂,进行湿分散处理,微粉化直到细胞的体积一体化粒度分布的中值粒径(D50) 身体达到1〜10μm,接着粉碎,或酵母细胞体进行湿分散处理,并进行微粉化,直到细胞体的体积一体化粒度分布的中值粒径(D50)达到1〜10μm 加入分散剂,进行粉化。