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    • 6. 发明专利
    • Oral bone-strengthening composition and food, drink, medicine or feed containing the same
    • 口服骨骼强化组合物和食物,饮料,药物或饲料
    • JP2013224277A
    • 2013-10-31
    • JP2012097188
    • 2012-04-20
    • Arimento Kogyo Kkアリメント工業株式会社
    • FUKAZAWA TAKEHITOONO HIROYUKITAGUCHI KUNIAKI
    • A61K38/00A23K1/16A23K1/175A61K31/593A61K33/42A61K38/17A61P19/08A61P19/10A61P43/00C07K14/435
    • PROBLEM TO BE SOLVED: To provide an oral bone-strengthening composition which is orally intakable routinely and continuously, has a bone-strengthening effect, is safe and inexpensive, and can be used for not only a medicine but also a food and drink, feed and the like; and to provide a food and drink, a medicine, or feed using the same.SOLUTION: An oral bone-strengthening composition includes at least component (a) and component (b). A food and drink, medicine, or feed includes the oral bone-strengthening composition. (a): Composite particles of hydroxyapatite/collagen type I obtained by mixing a dispersion liquid of fine particles of hydroxyapatite and an aqueous solution of collagen type I extracted from fish scales using an acidic aqueous solution. (b): Yolk-derived peptide obtained by removing water from a peptide aqueous solution which is obtained by decomposing water-soluble components, by a protease, in yolk extracted from yolk with water after removing ethanol-soluble components from the yolk.
    • 要解决的问题:提供一种口服可口的骨强化组合物,其口服可定期连续,具有骨强化作用,安全廉价,不仅可用于药物,还可用于食品和饮料,饲料 等等; 并提供食物和饮料,药物或使用其的饲料。解决方案:口服骨强化组合物至少包含组分(a)和组分(b)。 食物和饮料,药物或饲料包括口服骨骼强化组合物。 (a):通过使用酸性水溶液混合从鱼鳞提取的羟基磷灰石微粒分散液和I型胶原水溶液得到的羟基磷灰石/ I型胶原复合颗粒。 (b):从去除蛋黄中的乙醇可溶成分后,从水中提取出的蛋黄中的蛋黄质中分解水溶性成分得到的肽水溶液中的水分,得到的蛋黄衍生肽。