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81. 发明专利

JP2012008151A Method and device for quick electrochemical analysis 有权
标题翻译：快速电化学分析的方法和装置
公开(公告)号：JP2012008151A
公开(公告)日：2012-01-12
申请号：JP2011226547
申请日：2011-10-14
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： SHERRY GUO , ALASTAIR HODGES , RON CHATELIER , BIN CHANG
IPC分类号： G01N27/416 , G01N27/26 , G01N27/327 , G01N27/42
CPC分类号： A61B5/14532 , A61B5/1486 , A61B2562/0295 , G01N27/3273
摘要： PROBLEM TO BE SOLVED: To obtain concentration of an analyte in a physiological sample electrochemically.SOLUTION: A method of obtaining concentration of an analyte in a physiological sample electronically includes the steps of: (a) introducing the physiological sample into an electrochemical cell; (b) adding a first voltage having a first polarity to the electrochemical cell to measure a cell charge as a function of the time in order to obtain a first time-charge transient phenomenon; (c) adding a second voltage having a second polarity that is reverse to the first polarity to the electrochemical cell to measure the cell charge as the function of the time in order to obtain a second time-charge transient phenomenon; (d) calculating a first electric charge value from the second time-charge transient phenomenon; (e) calculating a second electric charge value from the second time-charge transient phenomenon, and a third electric charge value from the first time-charge transient phenomenon; (f) calculating a ratio based on the second and third electric charge values; and (g) multiplying the first electric charge value including no background value by the ratio to determine the concentration of the analyte.
摘要翻译：要解决的问题：电化学地获得生理样品中分析物的浓度。解决方案：以电子方式获得生理样品中分析物的浓度的方法包括以下步骤：（a）将生理样品引入电化学电池; （b）向电化学电池添加具有第一极性的第一电压以测量作为时间的函数的电池电荷，以便获得第一时间充电暂态现象; （c）向所述电化学电池添加具有与所述第一极性相反的第二极性的第二电压以测量所述电池电荷作为所述时间的函数，以便获得第二时间充电暂态现象; （d）从所述第二时间充电瞬态现象计算第一电荷值; （e）从所述第二时间充电瞬态现象计算第二电荷值，以及从所述第一时间充电暂态现象计算第三电荷值; （f）基于第二和第三电荷值计算比率; 和（g）将不包含背景值的第一电荷值乘以比例以确定分析物的浓度。版权所有（C）2012，JPO＆INPIT

82. 发明专利

JP2011164116A System and method for measuring analyte in sample 有权
标题翻译：用于测量样品中分析物的系统和方法
公开(公告)号：JP2011164116A
公开(公告)日：2011-08-25
申请号：JP2011123761
申请日：2011-06-01
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： CHATELIER RONALD C , HODGES ALASTAIR MCINDOE , NANDAGOPALAN SANTHANAGOPALAN
IPC分类号： G01N27/26 , G01N27/327 , G01N27/416
CPC分类号： G01N27/4163 , C12Q1/006 , G01N27/3274
摘要： PROBLEM TO BE SOLVED: To provide a method of determining a corrected analyte concentration in view of a partial error source. SOLUTION: The methods can be utilized for the determination of various analytes and/or various sources of errors. In one example, the method can be configured to determine a corrected glucose concentration in view of an extreme level of hematocrit found within the sample. In other embodiments, methods are provided for identifying various system errors and/or defects. For example, such errors can include partial-fill or double-fill situations, high track resistance, and/or sample leakage. Systems are also provided for determining a corrected analyte concentration and/or detecting a partial system error. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供鉴于部分误差源确定校正的分析物浓度的方法。解决方案：该方法可用于确定各种分析物和/或各种错误来源。在一个示例中，该方法可以被配置为鉴于在样品内发现的血细胞比容的极端水平来确定校正的葡萄糖浓度。在其他实施例中，提供了用于识别各种系统错误和/或缺陷的方法。例如，这种错误可以包括部分填充或双重填充情况，高跟踪阻抗和/或样本泄漏。还提供了用于确定校正的分析物浓度和/或检测部分系统误差的系统。版权所有（C）2011，JPO＆INPIT

83. 发明专利

JP4650870B2 Solution drying system 有权
公开(公告)号：JP4650870B2
公开(公告)日：2011-03-16
申请号：JP2002344332
申请日：2002-11-27
申请人：ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人：アーロン・ジェッセン , ギャリー・オタケ , ケネス・ダブリュ・ディック
IPC分类号： G01N27/416 , G01N33/483 , C12Q1/04 , G01N27/327 , G01N27/42 , G01N33/49
CPC分类号： G01N27/3272

84. 发明专利

JP2010008413A Method for measuring analyte in bodily fluid 有权
标题翻译：用于测量体液中分析物的方法
公开(公告)号：JP2010008413A
公开(公告)日：2010-01-14
申请号：JP2009146470
申请日：2009-06-19
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： MAHONEY JOHN , CHU CAROLINE , PERASSO HERB , TANNENBAUM SUSAN , JONES JANICE , LEONG KOON-WAH , DAVIS JOHN CHRISTOPHER
IPC分类号： G01N27/28 , G01N27/327 , G01N27/416
CPC分类号： G01N33/52
摘要： PROBLEM TO BE SOLVED: To provide a method for measuring (e.g., detecting and/or measuring the concentration of) an analyte in a bodily fluid sample, including processes for: obtaining a bodily fluid sample; applying the bodily fluid sample to an analyte test strip; transferring the applied bodily fluid sample to a sample-receiving chamber of the analyte test strip; and measuring an analyte in the bodily fluid sample. SOLUTION: The analyte test strip employed in the method includes a first port in fluidic communication with the sample-receiving chamber and proximate a platform portion of the analyte test strip. Moreover, the platform portion is configured to receive a first (relatively large) bodily fluid sample of at least 5 micro-liters and transfer at least a portion of the first bodily fluid sample to the sample-receiving chamber via the first port. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供用于测量（例如，检测和/或测量体液样品中的分析物的浓度）的方法，包括以下步骤：获得体液样品; 将体液样品施加到分析物测试条上; 将所施加的体液样品转移到分析物测试条的样品接收室; 并测量体液样品中的分析物。解决方案：该方法中使用的分析物测试条包括与样品接收室流体连通并且靠近分析物测试条的平台部分的第一端口。此外，平台部分被配置为接收至少5微升的第一（相对大的）体液样品，并且经由第一端口将至少一部分第一体液样品转移到样品接收室。版权所有（C）2010，JPO＆INPIT

85. 发明专利

JP2010008411A Analyte test strip for accepting diverse sample volumes 有权
标题翻译：分析样品量的分析测试条
公开(公告)号：JP2010008411A
公开(公告)日：2010-01-14
申请号：JP2009146468
申请日：2009-06-19
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： MAHONEY JOHN , CHU CAROLINE , PERASSO HERB , TANNENBAUM SUSAN , JONES JANICE , LEONG KOON-WAH , DAVIS JOHN CHRISTOPHER
IPC分类号： G01N35/02
CPC分类号： G01N33/525
摘要： PROBLEM TO BE SOLVED: To provide an analyte test strip for accepting diverse bodily fluid sample volumes, including a first insulating layer, a second insulating layer disposed above the first insulating layer, and a third insulating layer disposed below the first insulating layer. SOLUTION: The third insulating layer has a platform portion that extends beyond the first and second insulating layers and an upper surface. The analyte test strip also has a patterned spacer layer positioned between the first and second layers. The patterned spacer layer defines a channel between the first and second insulating layers that has a sample-receiving chamber, a first port proximate the platform portion and a second port at an outer edge of the analyte test strip. Moreover, the first port and the second port are in fluidic communication with the sample-receiving chamber. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于接受不同体液样品体积的分析物测试条，包括第一绝缘层，设置在第一绝缘层上方的第二绝缘层和设置在第一绝缘层下方的第三绝缘层。解决方案：第三绝缘层具有延伸超过第一绝缘层和第二绝缘层的平台部分和上表面。分析物测试条还具有位于第一和第二层之间的图案化间隔层。图案化间隔层在第一和第二绝缘层之间限定通道，其具有样品接收室，靠近平台部分的第一端口和分析物测试条的外边缘处的第二端口。此外，第一端口和第二端口与样品接收室流体连通。版权所有（C）2010，JPO＆INPIT

86. 发明专利

JP4383090B2 How to check the concentration of the analyte detection system and the specimen 有权
公开(公告)号：JP4383090B2
公开(公告)日：2009-12-16
申请号：JP2003130423
申请日：2003-05-08
申请人：ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人：デビン・ムカリスター , ローリン・オルソン
IPC分类号： A61B5/145 , G01N33/49 , A61B5/15 , A61B5/151 , A61B5/157
CPC分类号： A61B5/14532 , A61B5/150022 , A61B5/15019 , A61B5/150198 , A61B5/150259 , A61B5/150358 , A61B5/150419 , A61B5/150427 , A61B5/150435 , A61B5/150824 , A61B5/15111 , A61B5/15117 , A61B5/15153 , A61B5/15174 , A61B5/15176 , A61B5/1518 , A61B5/15182 , A61B5/15184 , A61B5/157
摘要： A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the biologic fluid sample after a lancet and lancing device are used in combination to pierce the skin. The system preferably includes a device comprising two body portions that slide relative to each other to both cock and fire a test strip at a target site. Meter reading and test strip disposal may be accomplished by removing the device from the target site. The device preferably employs a magazine loaded with test strips, with one strip being taken from the magazine each time the device is actuated. It preferably also includes a magazine in a cap to store spent test strips for disposal. The device may be turned on an off simply by removal and return of the cap.

87. 发明专利

JP4290415B2 Solution stripe structure formation system 有权
公开(公告)号：JP4290415B2
公开(公告)日：2009-07-08
申请号：JP2002344353
申请日：2002-11-27
申请人：ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人：アーロン・ジェッセン , ギャリー・オタケ , ケネス・ダブリュ・ディック
IPC分类号： B05C5/02 , G01N31/22 , B05D1/26 , B05D7/00 , G01N21/77 , G01N21/78 , G01N27/30 , G01N33/487
CPC分类号： B05C5/0254 , B05C5/027

88. 发明专利

JP2009106754A Integrated conduit insertion medical device 有权
标题翻译：集成电路插入式医疗器械
公开(公告)号：JP2009106754A
公开(公告)日：2009-05-21
申请号：JP2008278919
申请日：2008-10-29
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： KRULEVITCH PETER , CICHOCKI FRANK , OLSON LORIN P
IPC分类号： A61M5/158 , A61L29/00 , A61M5/145 , A61M5/32
CPC分类号： A61M5/158 , A61M5/3286 , A61M5/3287 , A61M5/329 , A61M25/00 , A61M25/0068 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266
摘要： PROBLEM TO BE SOLVED: To provide a small medical device facilitating insertion into a user's target site so that it is easily applied to any location on the body that can be touched by the user. SOLUTION: A medical device 900 includes a medical device flexible conduit 902 that has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also has a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, with the channel and the flexible tube defining a conduit. The medical device also includes an insertion mechanism configured to insert a portion of the flexible conduit, including the sharp head, into a user's target site such that the conduit provides fluid communication to the target site. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供便于插入用户的目标站点的小型医疗设备，使得其容易地应用于身体上可被用户触摸的任何位置。解决方案：医疗装置900包括医疗装置柔性导管902，其具有细长的镍钛诺带，其具有远端，近端，从远端延伸到近端的纵向轴线，从头部远端和在其中蚀刻的通道。此外，通道沿着纵向轴线布置。医疗器械柔性导管还具有柔性管，其至少部分地将细长的镍钛诺带夹在远端和近端之间，通道和柔性管限定导管。该医疗装置还包括插入机构，该插入机构构造成将包括尖头的柔性导管的一部分插入使用者的目标部位，使得导管向目标部位提供流体连通。版权所有（C）2009，JPO＆INPIT

89. 发明专利

JP2009085950A Systems and methods of determining control solution from physiological sample 有权
标题翻译：从生理样品中确定控制解决方案的系统和方法
公开(公告)号：JP2009085950A
公开(公告)日：2009-04-23
申请号：JP2008248444
申请日：2008-09-26
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： CHATELIER RONALD C , HODGES ALASTAIR MCINDOE
IPC分类号： G01N27/416 , G01N27/26 , G01N27/327
CPC分类号： C12Q1/001 , G01N27/3274 , G01N33/5438 , G01N33/96
摘要： PROBLEM TO BE SOLVED: To provide a system and a method for determining a water soluble solution (for example, control solution) which does not contain blood in a discriminating manner from a blood sample. SOLUTION: In one embodiment, this method measures a plurality of transient currents by an instrument, electrically connected to an electrochemical test piece by using a test piece. The transient current is used to determine which of the blood sample or the water-soluble solution that does not contain the blood a sample is, based on at least two characteristics (for example, the amount of an existing interference substance and a reaction rate). The method can also include a method for calculating a determination criterion, based on at least the two characteristics. This specifications provide various aspects of the system for determining the blood sample in a discriminating manner from the water soluble solution not containing the blood. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种以与血液样品不同的方式测定不含血液的水溶性溶液（例如对照溶液）的系统和方法。解决方案：在一个实施例中，该方法通过仪器测量多个瞬态电流，通过使用测试片与电化学测试片电连接。基于至少两个特征（例如，现有干扰物质的量和反应速率），使用瞬态电流来确定哪个血液样品或不含有血液的水溶液是哪一种，。该方法还可以包括至少基于两个特征来计算确定标准的方法。该规范提供了用于以不含血液的水溶性溶液的鉴别方式测定血液样品的系统的各个方面。版权所有（C）2009，JPO＆INPIT

90. 发明专利

JP2008197102A Method of ensuring date and time on test meter are accurate 有权
标题翻译：在测试仪上确保日期和时间的方法是准确的
公开(公告)号：JP2008197102A
公开(公告)日：2008-08-28
申请号：JP2008029667
申请日：2008-02-08
申请人： Lifescan Inc , ライフスキャン・インコーポレイテッドLifescan,Inc.
发明人： RAY PINAKI , MATIAN GREG , ARNDT CARRIE , KRAFT ULRICH , BAILEY ERIC , FREELEN MURPHY , OLSON MARK H , TAYLOR DAVID
IPC分类号： G01N27/26 , A61B5/1455 , A61B5/1486 , G01N27/416
CPC分类号： A61B5/14532 , A61B5/14551 , A61B5/1477 , A61B2560/0276 , A61B2562/0295 , G01N33/48792 , G06F19/322 , G06F19/3406 , G06F19/3412 , G16H10/60 , G16H40/40 , G16H40/63
摘要： PROBLEM TO BE SOLVED: To provide a method of operating a glucose test meter. SOLUTION: This method can be achieved by storing a plurality of glucose readings to a first memory of the test meter, each of the glucose readings having a time stamp and an order index, the time stamp comprising a date and a time when the glucose reading is performed, the order index indicating an order in which the plurality of glucose readings is saved to the first memory; determining whether successively saved glucose readings have time stamps in chronological order consistent with the order index; and indicating that the date and the time setting in the test meter are incorrect if there are successively saved glucose readings having time stamps inconsistent with the order index. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种操作葡萄糖测试仪的方法。解决方案：该方法可以通过将多个葡萄糖读数存储到测试计的第一存储器来实现，每个葡萄糖读数具有时间标记和订单索引，该时间戳包括日期和时间执行葡萄糖读数，指示将多个葡萄糖读数保存到第一存储器的顺序的顺序指数; 确定连续保存的葡萄糖读数是否具有与订单指数一致的时间顺序的时间戳; 并且如果具有与订单索引不一致的时间戳的连续保存的葡萄糖读数，则表示测试计的日期和时间设置不正确。版权所有（C）2008，JPO＆INPIT

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