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61. 发明专利

JPS63251092A PRODUCTION OF ALUBUMIN 失效
公开(公告)号：JPS63251092A
公开(公告)日：1988-10-18
申请号：JP8527787
申请日：1987-04-07
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , INOMATA SHINJI , SETO SUSUMU , YANAGI MITSUO
IPC分类号： C12P19/02 , C12P19/44 , C12R1/91
摘要： PURPOSE:To produce albumin in high yield, by adding hydroquinone and

62. 发明专利

JPS62181795A PRODUCTION OF ALKYLHYDROQUINONE-BETA-D-GLUCOSIDE 失效
公开(公告)号：JPS62181795A
公开(公告)日：1987-08-10
申请号：JP2517786
申请日：1986-02-07
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , FUJINUMA YOSHIMORI , ASAHARA TOMOHISA
IPC分类号： C12P19/44 , C12N5/00 , C12N5/04 , C12R1/91
摘要： PURPOSE:To separate and collect an alkylhydroquinone-beta-D-glucoside useful as a beautifying and whitening agent, by adding an alkylhydroquinone to a tissual culture medium of a plant callus or tumorous tissue and carrying out cultivation. CONSTITUTION:Cell groups or pieces of tissues of seedling root, hypocotyl, cotyledon, stem, flower, leaf, etc., of a plant, e.g. Catharanthis roseus L., etc., as a starting material are sterilized and cultivated according to an ordinary method to induce a callus. The formation of the callus is carried out using a solid culture medium containing agar, e.g. Murashige-Skoog culture medium, White culture medium, etc., and the induced callus is then subcultured in a liquid culture medium without adding agar by shaking culture. The subculture is carried out and an alkylhydroquinone is added to the culture medium to continue culture. After several days, the resultant culture is recovered to obtain the aimed alkylhydroquinone-beta-D-glucoside expressed by the formula from the culture by a well-known method.

63. 发明专利

JPS61124391A Production of arbutin 失效
标题翻译：生产ARBUTIN
公开(公告)号：JPS61124391A
公开(公告)日：1986-06-12
申请号：JP24357984
申请日：1984-11-16
申请人： Shiseido Co Ltd
发明人： YOKOYAMA MINEYUKI
IPC分类号： C12P19/44 , C12R1/91
摘要： PURPOSE: To accumulate an extremely large amount of arbutin, and separate and obtain the arbutin, by adding hydroquinone to the medium for the tissue culture of callus or tumor tissue of Lochnera rosea.
CONSTITUTION: The cell or tissue of the root, hypocotyl, cotyledon, etc. of the seedlings of Lochnera rosea is used as the starting material, and is cultured in a medium added with auxin or cytokinin by conventional process to induce a callus. The medium is usually the one prepared by mixing agar to Murashige- Skoog medium. The induced callus is subcultured in the above liquid medium free from agar, and cultured under shaking. The culture is carried out at 20W27°C with or without irradiation of light. The callus is subcultured to a fresh medium once a week. In the above process, hydroquinone is added to the medium after one week from the induction of callus at a concentration of ≤10mM, especially preferably 2W5mM, and the produced arbutin is separated from the cultured product.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：积累极大量的熊果苷，并分离并获得熊果苷，将氢醌加入培养基中用于组织培养Lochnera rosea的愈伤组织或肿瘤组织。构成：将罗汉果秧苗的根，下胚轴，子叶等细胞或组织用作起始原料，并通过常规方法在通过常规方法加入生长素或细胞分裂素的培养基中培养以诱导愈伤组织。培养基通常是通过将琼脂与Murashige-Skoog培养基混合而成的。将诱导的愈伤组织在不含琼脂的上述液体培养基中传代培养，并在振荡下培养。培养在20-27摄氏度下进行或不用光照射。将愈伤组织每周一次传代培养至新鲜培养基。在上述过程中，将氢醌从诱导愈伤组织起一周后以浓度<10mM，特别优选2-5mM加入到培养基中，并将生产的熊果苷从培养产物中分离。

64. 发明专利

JP2007002000A SURFACE-COATED POWDER AND COSMETIC CONTAINING THE SAME 审中-公开
公开(公告)号：JP2007002000A
公开(公告)日：2007-01-11
申请号：JP2005180346
申请日：2005-06-21
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , MAEDA KAZUHISA , FUKUHARA TADAO
IPC分类号： C09C3/08 , A61K8/19 , C09C1/28
摘要： PROBLEM TO BE SOLVED: To provide a surface-coated powder composed of an inorganic powder stably surface-coated with a large amount of an antioxidant substance. SOLUTION: The surface-coated powder is composed of an amino-containing inorganic powder surface-coated with a 1,3-diketone structure compound and/or a resorcinol structure compound. Alternatively, the surface coated powder is one wherein either a 1,3-diketone compound or a resorcinol compound is an antioxidant substance. COPYRIGHT: (C)2007,JPO&INPIT

65. 发明专利

JP2003113139A METHOD FOR USING HYDROXAMIC ACID AND/OR CATECHIN 审中-公开
公开(公告)号：JP2003113139A
公开(公告)日：2003-04-18
申请号：JP2001310761
申请日：2001-10-05
申请人： SHISEIDO CO LTD
发明人： IIDA TOSHIMOCHI , YAMAGUCHI SACHIKO , YOKOYAMA MINEYUKI
IPC分类号： C07C51/50 , A01N25/22 , A01N37/28 , A01N37/42 , A01N43/16 , C07C59/90
摘要： PROBLEM TO BE SOLVED: To provide a means for stably preserving over a long period a ketol fatty acid hopeful of having various effects including plant growth regulating effect. SOLUTION: This means for improving the stability of the ketol fatty acid to facilitate its long-term preservation involves a method of using hydroxamic acids and/or catechins comprising making the ketol fatty acid coexist with the hydroxamic acid and/or catechins.

66. 发明专利

JP2001233856A METHOD FOR SYNTHESIZING INDOLE DERIVATIVE 失效
公开(公告)号：JP2001233856A
公开(公告)日：2001-08-28
申请号：JP2000047141
申请日：2000-02-24
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , YAMAGUCHI SACHIKO , IIDA TOSHIMOCHI , KOBAYASHI KOJI
IPC分类号： C07D405/04 , C07D209/18
摘要： PROBLEM TO BE SOLVED: To provide a method for synthesizing indole derivatives by which the indole derivatives (I) and/or (II) can be synthesized in high yields ant at reduced reaction steps. SOLUTION: This method for synthesizing the indole derivatives (I) and/or (II), characterized by reacting indole with an aliphatic saturated dicarboxylic acid and then reducing the obtained products. Thereby, the indole derivatives (I) and/or (I) can be synthesized in high yields (>=20%) at reduced reaction steps such as two to four steps.

67. 发明专利

JP2000129284A PREPARATION OF NATURAL PERFUME 失效
公开(公告)号：JP2000129284A
公开(公告)日：2000-05-09
申请号：JP32154498
申请日：1998-10-27
申请人： SHISEIDO CO LTD
发明人： AITSU YOKO , HAJI SHINICHIRO , YOMOGIDA KATSUYUKI , YOKOYAMA MINEYUKI
IPC分类号： A61K8/96 , A61K8/00 , A61K8/18 , A61K8/97 , A61Q13/00 , C11B9/02
摘要： PROBLEM TO BE SOLVED: To provide a means for easily preparing a natural perfume by shortening the aging period of the natural perfume. SOLUTION: In a preparation process of a natural perfume, a plant having a potential as a natural perfume material is promptly homogenized after harvest, the aging of a natural perfume in the homogenized plant is promoted, and the aged natural perfume is extracted. Otherwise, in a preparation process of a natural perfume, a plant having a potential as a natural perfume material is promptly homogenized after harvest, the homogenized plant is continuously heated, the aging of a natural perfume in the homogenized plant is promoted, and the aged natural perfume is extracted.

68. 发明专利

JPH1129410A FLOWER BUD FORMATION-INDUCING AGENT AND FLOWER BUD FORMATION-INDUCING KIT 失效
公开(公告)号：JPH1129410A
公开(公告)日：1999-02-02
申请号：JP34867897
申请日：1997-12-02
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , YAMAGUCHI SACHIKO , SAKAMOTO OKIHIKO , KOJIMA KIYOTAKA , FUKUI HIROSHI
IPC分类号： A01N37/06 , A01N37/42
摘要： PROBLEM TO BE SOLVED: To obtain a flower bud formation-inducing agent directly acting on the flower bud formation of plants and a flower bud formation-inducting kit. SOLUTION: The flower bud formation-inducing agent and the flower bud formation-inducing kit containing this flower bud formation-inducing agent contain in principle, a ketol fatty acid in which one of the different two carbon atoms selected from the carbon atoms out from 2 to n-positions is the carbon atom constructing a carbonyl group and the other is the carbon atom linking to a hydroxy group and the number of the carbon atoms (n) of the ketol fatty acid is 424, as an active ingredient.

69. 发明专利

JPH10324602A FLOWER BUD FORMATION INDUCER AND FLOWER BUD FORMATION INDUCING KIT 失效
公开(公告)号：JPH10324602A
公开(公告)日：1998-12-08
申请号：JP14107697
申请日：1997-05-15
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , YAMAGUCHI SACHIKO , SAKAMOTO OKIHIKO , KOJIMA KIYOTAKA , TAKIMOTO ATSUSHI
IPC分类号： A01N37/42 , A01N33/10
摘要： PROBLEM TO BE SOLVED: To obtain the subject inducer widely having a desired flower bud formation inducing activity to a plant by making the inducer contain a specific α-ketole unsaturated fatty acid directly relating to blossom as an active component. SOLUTION: This inducer is obtained by solely containing an α-ketole unsaturated fatty acid of the formula general name: 9-hydroxy-10oxo-cis-12(Z),15(Z)- octadecadienoic acid} obtained by extracting from Lemna paucicostata as one kind of a family Lemnaceae plant, applying an enzyme such as lipoxygenase to α-linolenic acid (i.e., cis-9,12,15-octadecatrienoic acid) according to a fatty acid metabolizing route in a plant body or producing by a usual chemical synthesis, or combinedly containing with norepinephrine.

70. 发明专利

JPH1072312A PREPARATION FOR EXTERNAL USE FOR SKIN 失效
公开(公告)号：JPH1072312A
公开(公告)日：1998-03-17
申请号：JP25094596
申请日：1996-09-02
申请人： SHISEIDO CO LTD
发明人： YOKOYAMA MINEYUKI , YOSHIDA YUZO , KITAMURA KANEMOTO , SAKAMOTO OKIHIKO
IPC分类号： A61K8/96 , A61K8/00 , A61K8/73 , A61K8/97 , A61Q1/00 , A61Q1/12 , A61Q19/00 , A61K7/00 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To obtain a preparation for external use for skin having a preventing.improving effect not only on roughened skin of a healthy person or a person whose skin is susceptible to chapping but also on roughened skin symptom caused by various skin diseases such as cutaneous sensitization, psoriasis, etc., by formulating acid decomposition product of a specific polysaccharide. SOLUTION: An acid decomposition product of inulin is used. Chicory, sunchoke, burdock, elecampane, carduus, acetabularia, etc., are used as the raw material of inulin, especially the root of chicory is preferred. The acid decomposition product of the inulin is obtained, for example, by adding a strong acid such as hydrochloric acid, sulfuric acid, nitric acid, etc., to an inulin and allowing to acidify the inulin, etc. The preferable formulating amount of the inulin acid decomposition product is >=0.005wt.% and

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