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51. 发明专利

JP2007047025A Manufacturing method of filler for carbonyl compound collection 审中-公开
标题翻译：碳化合物收集填料的制备方法
公开(公告)号：JP2007047025A
公开(公告)日：2007-02-22
申请号：JP2005231871
申请日：2005-08-10
申请人： Showa Denko Kk , 昭和電工株式会社
发明人： YAMAGAMI ISAO
IPC分类号： G01N30/50 , B01J20/283 , G01N30/00 , G01N30/06 , G01N30/26 , G01N30/56 , G01N30/88
摘要： PROBLEM TO BE SOLVED: To provide a manufacturing method of a filler for carbonyl compound collection, simple and inexpensive, having excellent reproducibility, and capable of analyzing a trace amount of a carbonyl compound, while keeping a high recovery rate, and the filler for carbonyl compound collection, and a column for carbonyl compound collection.
SOLUTION: The manufacturing method of the filler for carbonyl compound collection has in due order a process (1) for cleaning an inorganic carrier with an organic solvent including an acid material, and a process (2) for allowing the inorganic carrier cleaned in the process (1) to adsorb a hydrazine compound.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：解决问题的方法：为了提供简单且便宜的羰基化合物收集用填料的制造方法，具有优异的再现性，能够在保持高回收率的同时分析痕量的羰基化合物，用于羰基化合物收集的填料和用于羰基化合物收集的柱。解决方案：用于羰基化合物收集的填料的制造方法有适当的顺序是用含有酸性材料的有机溶剂清洗无机载体的方法（1）和用于使无机载体清洁的方法（2）在方法（1）中吸附肼化合物。版权所有（C）2007，JPO＆INPIT

52. 发明专利

JP3866179B2 有权
公开(公告)号：JP3866179B2
公开(公告)日：2007-01-10
申请号：JP2002296533
申请日：2002-10-09
IPC分类号： B01J20/291 , B01D15/18 , B01D15/38 , B01J20/24 , B01J20/26 , B01J20/28 , B01J20/281 , B01J20/283 , B01J20/286 , B01J20/29 , B01J20/30 , B01J20/32 , G01N30/56 , G01N30/88

53. 发明专利

JP3856763B2 Method of manufacturing a microfluidic device 有权
公开(公告)号：JP3856763B2
公开(公告)日：2006-12-13
申请号：JP2003064912
申请日：2003-03-11
申请人：財団法人川村理化学研究所
发明人：敦司寺前 , 孝典穴澤 , 哲生高田
IPC分类号： G01N30/60 , G01N37/00 , B81C99/00 , G01N30/52 , G01N30/56 , G03F7/20
CPC分类号： G01N30/6052 , G01N30/6095 , G01N2030/525 , G01N2030/562 , Y10T137/2224

54. 发明专利

JP3840524B2 Hollow capillary column and a method of manufacturing the same 有权
公开(公告)号：JP3840524B2
公开(公告)日：2006-11-01
申请号：JP2000043431
申请日：2000-02-21
申请人：株式会社ケムコ , 孝雄津田
发明人：慎也北川 , 眞徳宗末 , 孝雄津田
IPC分类号： G01N30/60 , B01D15/08 , B01J20/281 , B01J20/283 , G01N30/52 , G01N30/56 , G01N30/88
CPC分类号： B01J20/286 , B01J20/28054 , B01J20/28097 , B01J20/282 , B01J2220/54 , B01J2220/84 , G01N30/52 , G01N30/6078 , G01N2030/525 , G01N2030/567
摘要： In an open capillary column, a stationary phase is formed on the inner wall of a capillary tube. This stationary phase comprises a number of pores on the surface of the capillary tube, and each of pore has an expanded hollow in the stationary phase. A manufacturing method of an open capillary column comprises the steps of giving alkaline treatment to an inner wall of an open capillary tube, applying one of oligo silica, oligo zirconia and oligo titania on the inner wall, filling the open capillary tube with alkaline solution to form one of a silica layer, a zirconia layer and titania layer, discharging the alkaline solution and heat-treating the capillary tube to form a base of a stationary phase. The open capillary column of the present invention comprises a stationary phase having a very large surface area. It is useful for a separation analysis field such as liquid chromatography and electrochromatography.

55. 发明专利

JP2006284440A Manufacturing method of chip for chromatography 审中-公开
标题翻译：色谱芯片的制造方法
公开(公告)号：JP2006284440A
公开(公告)日：2006-10-19
申请号：JP2005106442
申请日：2005-04-01
申请人： Fluidware Technologies Kk , Ymc Co Ltd , フルイドウェアテクノロジーズ株式会社 , 株式会社ワイエムシィ
发明人： KONDO MASARU , MAGUCHI TAKAHIDE , YOSHIDA TOSHIO
IPC分类号： G01N30/60 , G01N30/56 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a manufacturing method of a chip for chromatography formed by filling particles in a microchannel.
SOLUTION: This manufacturing method of a microchip for chromatography having a substrate wherein the microchannel having a prescribed shape is formed on the surface; a cover plate sealed on the substrate surface; trap parts formed on at least two spots in the microchannel, for restricting flow of the filler; and the filler filled between the trap parts in the microchannel, has a filling process for applying slurry formed by dispersing the filler from the surface side of the substrate, and thereby filling the filler between the trap parts in the microchannel; a removing process for removing the slurry remaining on the surface side of the substrate after the filling process; and a sealing process for sealing the cover plate on the substrate surface.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供通过在微通道中填充颗粒而形成的用于色谱的芯片的制造方法。解决方案：具有基板的用于色谱的微芯片的制造方法，其中具有规定形状的微通道形成在表面上; 密封在基板表面上的盖板; 捕获部分形成在微通道中的至少两个点上，用于限制填料的流动; 并且填充在微通道中的捕集部分之间的填料具有用于施加通过从衬底的表面侧分散填料而形成的浆料的填充工艺，从而将填料填充在微通道中的捕集部分之间; 用于去除在填充过程之后剩余在基板的表面侧上的浆料的去除工艺; 以及用于将盖板密封在基板表面上的密封工艺。版权所有（C）2007，JPO＆INPIT

56. 发明专利

JP2006250920A Chromatography column 有权
标题翻译：色谱柱
公开(公告)号：JP2006250920A
公开(公告)日：2006-09-21
申请号：JP2006015228
申请日：2006-01-24
申请人： Varian Bv , ヴァリアン,ベー.フェー.
发明人： BIERMANS FRANCISCUS , DUVEKOT JACOBUS
IPC分类号： G01N30/88 , B01J20/281 , C08G65/22 , G01N30/56 , G01N30/60
CPC分类号： B01J20/262 , B01J20/26 , B01J20/285 , B01J2220/84
摘要： PROBLEM TO BE SOLVED: To improve thermal stability of a stationary phase of a chromatography column. SOLUTION: This chromatography column includes the stationary phase comprising a deuterated poly(ethylene glycol) or another deuterated polymer. The stationary phase can be formed using the method quitely same to a method used when forming a stationary phase comprising a non-deuterated polymer equivalent thereto. The deuterated poly(ethylene glycol) or the another deuterated polymer preferably has an increased thermal stability, compared with the non-deuterated poly(ethylene glycol) or the non-deuterated polymer equivalent thereto. Bleeding of the stationary phase is thereby reduced during gas chromatography to allow an operation at a high temperature. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提高色谱柱的固定相的热稳定性。该色谱柱包括包含氘代聚（乙二醇）或另一种氘代聚合物的固定相。可以使用与形成包含与其相当的非氘代聚合物的固定相时使用的方法非常相似的方法来形成固定相。与非氘化聚（乙二醇）或与其相当的非氘代聚合物相比，氘化聚（乙二醇）或另一氘代聚合物优选具有增加的热稳定性。因此，在气相色谱法中，固定相的渗色减少，以允许在高温下进行操作。版权所有（C）2006，JPO＆NCIPI

57. 发明专利

JP2006095516A Surface-modified filler for liquid chromatography and manufacturing method for the same 审中-公开
标题翻译：用于液相色谱的表面改性填料及其制造方法
公开(公告)号：JP2006095516A
公开(公告)日：2006-04-13
申请号：JP2005248583
申请日：2005-08-30
申请人： Showa Denko Kk , 昭和電工株式会社
发明人： SHINPO KUNIAKI , OKADA YOSHIHARU , TAKAHASHI RYUJI
IPC分类号： B01J20/285 , B01J20/281 , G01N30/26 , G01N30/32 , G01N30/56 , G01N30/74 , G01N30/86 , G01N30/88
摘要： PROBLEM TO BE SOLVED: To provide a filler for liquid chromatography restrained from adsorbing proteins such as albumin by modifying the surface of a carrier by a relatively easy method without substantially exerting influence on micro pores of the carrier having huge micro pores of 100 to 5,000 nm.
SOLUTION: The surface-modified filler for liquid chromatography is obtained by suspending the carrier having a polar group in a water soluble polymer solution, removing the water under reduced pressure to coat the surface of the carrier with the water soluble polymer and suspending the carrier with the surface of the carrier coated with the water soluble polymer in a solvent in which the water soluble polymer is insoluble to crosslink the water soluble polymer on the surface of the carrier. A manufacturing method for the same and a liquid chromatographic column using the filler are also disclosed.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供通过相对容易的方法改变载体表面而不是基本上对具有巨大微孔的载体微孔的影响而限制的蛋白质如白蛋白的液相色谱填充剂到5000nm。解决方案：用于液相色谱的表面改性填料是通过将具有极性基团的载体悬浮在水溶性聚合物溶液中，在减压下除去水而用水溶性聚合物涂覆载体的表面并悬浮载体，其载体的表面在水溶性聚合物不溶于水溶性聚合物的载体的表面上交联水溶性聚合物的溶剂中。还公开了使用该填料的制造方法和使用该填料的液相色谱柱。版权所有（C）2006，JPO＆NCIPI

58. 发明专利

JP2005533261A Method and apparatus for manufacturing a mass transfer device 审中-公开
公开(公告)号：JP2005533261A
公开(公告)日：2005-11-04
申请号：JP2004522736
申请日：2003-07-16
申请人：キヤノン株式会社
发明人：剛士今村 , 聡子大水 , 剛生山崎 , 直人御橋
IPC分类号： B01D15/20 , B01J19/00 , B01J20/281 , B01J20/283 , B01J20/287 , B01J23/72 , B01J35/04 , B01L3/00 , G01N30/46 , G01N30/56 , G01N30/60 , G01N30/88 , G01N30/48
CPC分类号： G01N30/466 , B01D15/206 , B01J19/0093 , B01J20/283 , B01J20/287 , B01J23/72 , B01J35/04 , B01J2219/00783 , B01J2219/00835 , B01J2219/00916 , B01L3/5027 , B01L3/502707 , B01L3/502753 , B01L2200/12 , G01N30/56 , G01N30/6043 , G01N30/6086 , G01N30/6095 , G01N2030/565
摘要：流路内に均一に充填剤を充填可能なそして基体上の流路に特定物質を含む流体を流すことで特定物質を移動させる物質移動装置の製造方法及びその製造装置を提供する。物質移動装置の製造方法は、基体を用意する工程と、基体の表面に流路を形成する工程と、流路内に、充填剤と液状媒体からなる液滴を付与する工程と、液状媒体を除去することにより、流路を充填剤で充填する工程とを有する。

59. 发明专利

JP3709554B2 Liquid introduction device of liquid chromatographic column 有权
公开(公告)号：JP3709554B2
公开(公告)日：2005-10-26
申请号：JP2000393785
申请日：2000-11-20
申请人：時男桐山
发明人：時男桐山
IPC分类号： G01N30/16 , G01N30/18 , G01N30/56 , G01N30/60
CPC分类号： G01N30/6026

60. 发明专利

JP2005531011A Separation system, the separation system components and methods for their preparation 有权
公开(公告)号：JP2005531011A
公开(公告)日：2005-10-13
申请号：JP2004518030
申请日：2003-06-26
申请人：テレダイン・イスコ・インコーポレーテッド
发明人：アリントン，ロバート・ダブリュー , シー，シャオフェン , ジャン，タオ , フー，ミンチェン
IPC分类号： B01J20/281 , B01D15/20 , B01J8/00 , B01J19/00 , B01J19/18 , B01J20/283 , B01J20/285 , C08F2/00 , G01N30/16 , G01N30/46 , G01N30/52 , G01N30/56 , G01N30/80 , G01N30/88 , G01N30/48 , G01N30/60
CPC分类号： B01J20/3064 , B01D15/206 , B01J8/0005 , B01J19/0013 , B01J19/18 , B01J20/283 , B01J20/285 , B01J2219/00162 , B01J2220/54 , B01J2220/82 , G01N30/56 , G01N2030/522 , G01N2030/528 , G01N2030/567 , G01N30/30
摘要： Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated.

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