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    • 59. 发明专利
    • Tandem quadrupole mass spectroscope
    • TANDEM QUADRUPOLE MASS SPECTROSCOPE
    • JP2013145637A
    • 2013-07-25
    • JP2012004689
    • 2012-01-13
    • Shimadzu Corp株式会社島津製作所
    • HARADA SHIGETOSHI
    • H01J49/42G01N27/62
    • H01J49/26G06K9/0051H01J49/0036H01J49/004H01J49/4215
    • PROBLEM TO BE SOLVED: To reduce spike noise which is significant when the sensitivity of a detector is increased in MS/MS analysis.SOLUTION: For all data obtained from an A/D converter during an integration period (dwell time), the data having a value exceeding a predetermined threshold is excluded from integration object up to a predetermined maximum delete number, and the values of remaining data are integrated thus obtaining one measurement data corresponding to the integration period thereof. Since the number of noise data reflecting jump-in of particle, causing spike noise, is negligible, the noise data is removed in a no-signal state where a target ion does not exist. When a target ion exists, not the noise data but the normal data may be possibly removed, but since the number of which is negligible when compared with the total number of data, the effect of removing normal data does not substantially appear in the integration result. Consequently, spike noise can be reduced effectively.
    • 要解决的问题:减少在MS / MS分析中检测器的灵敏度增加时显着的尖峰噪声。解决方案:对于在积分期间(停留时间)期间从A / D转换器获得的所有数据,数据具有 将超过预定阈值的值从积分对象中排除直到预定的最大删除号,并且剩余数据的值被积分,从而获得对应于其积分周期的一个测量数据。 由于反映微粒的跳入的噪声数据的数量,导致尖峰噪声是可以忽略的,因此在不存在目标离子的无信号状态下去除噪声数据。 当存在目标离子时,不是噪声数据而是正常数据可能被去除,而是由于与数据总数相比数量可忽略不计,所以在积分结果中基本上不会出现删除正常数据的效果 。 因此,可以有效地降低尖峰噪声。