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    • 26. 发明专利
    • Preparation of tertiary alcohol sulfuric ester salt
    • 碱性酒精硫酸盐盐的制备
    • JPS5759853A
    • 1982-04-10
    • JP13512780
    • 1980-09-30
    • Sogo Yatsukou Kk
    • YAMAGUCHI HACHIROU
    • C07C305/00C07C67/00C07C301/00C07C303/24C07C305/06
    • PURPOSE: To obtain the titled compound in high yield economically and advantageously without troublesome operation, by reacting a tertiary alcohol with an amine adduct with sulfur trioxide as a sulfating agent under heating, cooling the reaction mixture, and adding a slightly soluble solvent to isolate the titled compound.
      CONSTITUTION: All the tertiary alcohols not only tertiary butanol are heated with an adduct of an amine, e.g. methylamine, cyclopropylamine, aniline or pyridine, of the formula R1R2R3N(R1, R2R3 are H, 1W10C alkyl or cycloalkyl; however, except when any one of R1, R2 and R3 is H) with sulfur trioxide, in an amount of equimolar with the tertiary alcohols at 0W120°C, and cooled to 0°C or below, and then a slightly soluble solvent, e.g. methanol or petroleum ether is added to deposit and isolate the aimed substance. The tertiary alcohols may be used in a large excess.
      COPYRIGHT: (C)1982,JPO&Japio
    • 目的:经济,有利地获得高产量的标题化合物,无需麻烦的操作,通过在加热下使叔醇与作为硫酸化剂的三氧化硫的胺加合物反应,冷却反应混合物,并加入微溶的溶剂以分离 标题化合物。 构成:所有叔醇不仅是叔丁醇,与胺的加合物,例如, 甲基胺,环丙胺,苯胺或吡啶,式R1R2R3N(R1,R2R3为H,1-10C烷基或环烷基;但是,当R 1,R 2和R 3中的任何一个为H时,除三氧化硫之外),其量为等摩尔 叔醇在0-120℃下冷却至0℃或更低,然后加入微溶的溶剂, 加入甲醇或石油醚沉淀并分离目标物质。 叔醇可以大量使用。