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21. 发明专利

JPS61250548A COMPARING ELECTRODE 失效
公开(公告)号：JPS61250548A
公开(公告)日：1986-11-07
申请号：JP9147385
申请日：1985-04-26
申请人： HITACHI LTD
发明人： SHINDO ISAO , YOKOBAYASHI TOSHIAKI , KATO TERUO
IPC分类号： G01N27/30
摘要： PURPOSE:To enable highly accurate measurement by applying stable reference potential, by almost perfectly setting the potential between a liquid specimen and an internal liquid to earth potential. CONSTITUTION:The comparing electrode cell 1 of an apparatus for chemically measuring the electrolyte in a liquid is constituted of an insulating material and an internal electrode 2 is inserted in an internal liquid flow passage 6 communicated with an internal liquid injection port 4 and the leading end part thereof is contacted with the internal liquid. A common electrode 3 is constituted of platinum and the leading end conductor part thereof is formed into a cylindrical shape so as to cover the whole of the liquid communication part of the confluent point 7 of the internal liquid from the injection port 4 and the liquid specimen from a liquid specimen injection port 5. A common electrode lead wire 8 is arranged to said electrode 3 and an ion electrode 10 is inserted in the liquid specimen flow passage 11 of an electrode cell 9. Then, the potential between the liquid specimen and the internal liquid is perfectly brought to earth potential and the reception of the effect due to a confluent state is eliminated and stable reference potential is imparted to enable highly accurate measurement.

22. 发明专利

JPS5882151A ELECTROLYTE MEASUREMENT DEVICE 失效
公开(公告)号：JPS5882151A
公开(公告)日：1983-05-17
申请号：JP17973581
申请日：1981-11-11
申请人： HITACHI LTD
发明人： HIRAGOORI KAZUYOSHI , HASHIMOTO HIROSHI , YOKOBAYASHI TOSHIAKI
IPC分类号： G01N27/26 , G01N27/416
摘要： PURPOSE:To eliminate the effect of variation in electrode signal due to static electricity accumulated on the surface of the specimen vessel by integrating the signal from electrodes during rotation of a specimen vessel an integral number of times. CONSTITUTION:A specimen vessel 2 is rotated at a constant speed by a specimen vessel rotating mechanism 1. A voltage is developed between the electrode 3 in the specimen solution and a reference electrode 4 according to the concentration of a subject chemical substance in the specimen. This voltage is amplified by a signel amplifier 5 and sent to an integrator 6. In this integrator 6 input signals are integrated during the time in which the specimen vessel 2 rotates an integral number of times. The integration voltage is sent to a concentration conversion circuit 7. In this concentration conversion circuit 7 the output voltage of the integrator 6 is converted by reverse logarithium and converted to a voltage the corresponds to the concentration of the subject chemical substance. With this constitution error in the measurement due to static electricity that develops during the air is dry is eliminated. Accordingly always stable and highly accurate results can be obtained.

23. 发明专利

JP2004305009A Apparatus for amplifying nucleic acid and method for amplifying nucleic acid 审中-公开
标题翻译：放大核酸的装置及放大核酸的方法
公开(公告)号：JP2004305009A
公开(公告)日：2004-11-04
申请号：JP2003098744
申请日：2003-04-02
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： TAKENAKA HIROSHI , NAGAOKA YOSHIHIRO , WATABE SHIGEO , FUKUZONO SHINICHI , YOKOBAYASHI TOSHIAKI
IPC分类号： C12N15/09 , B01L3/00 , B01L7/00 , C12M1/00 , C12Q1/68 , G01N35/00
CPC分类号： B01L7/525 , B01L3/5027 , B01L2200/0605 , B01L2300/0809 , B01L2300/0861 , B01L2300/0864 , B01L2300/0867 , B01L2300/18 , G01N35/00029
摘要： PROBLEM TO BE SOLVED: To provide an apparatus for amplifying a nucleic acid with high amplification efficiency and to provide a method for amplifying the nucleic acid.
SOLUTION: There are provided a flow channel where a reaction liquid comprising a sample containing the nucleic acid and a reagent mixed with the sample flows, a flow channel branching part branching the flow channel into a plurality of branched flow channels, a joining part where the plurality of branched flow channels join and a joined flow channel where the joined reaction liquid is led. Furthermore, heating mechanisms equipped with a plurality of the set temperature zones in the branched flow channels are provided.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：提供用于扩增高扩增效率的核酸的装置，并提供扩增核酸的方法。解决方案：提供了一种流动通道，其中包含含有核酸的样品和与样品混合的试剂的反应液流动，将流路分支成多个分支流动通道的流路分支部分，多个分支流动通道连接的部分和连接的反应液体被引导的连接的流动通道。此外，提供了在分支流动通道中配备有多个设定温度区域的加热机构。版权所有（C）2005，JPO＆NCIPI

24. 发明专利

JPH102903A CALIBRATION METHOD FOR PHOTOMETRIC SYSTEM IN AUTOMATIC ANALYZER 失效
公开(公告)号：JPH102903A
公开(公告)日：1998-01-06
申请号：JP15814196
申请日：1996-06-19
申请人： HITACHI LTD
发明人： NAKADA RYOICHI , ISHIZAWA HIROAKI , YOKOBAYASHI TOSHIAKI
IPC分类号： G01N35/00 , G01N21/01
摘要： PROBLEM TO BE SOLVED: To provide the method for automating the calibration of the photometric system (logarithm converter) of an automatic analyzer. SOLUTION: In the photometric system of an automatic analyzer, the reference current Iref of a logarithm converter 18a is adjusted by a microprocessor 19, thereby the offset of an optical system is cancelled. This photometric system comprises the microprocessor 19, the logarithm converter 18a, an A/D converter 18b, a D/A converter 30 and a photodetector 33. In this case, the input current from the photodetector 33 at the time of the analysis of water undergoes the logarithm conversion and current/voltage conversion in the logarithm converter 18a and is converted to the digital quantity in the A/D converter 18b. The microprocessor 19 monitors the value, controls the data, which are imparted into the D/A converter 30, and adjusts the reference current Iref so that the output of the logarithm converter 18a is contained in the specified range.

25. 发明专利

JPH07163195A STEP MOTOR CONTROLLER 失效
公开(公告)号：JPH07163195A
公开(公告)日：1995-06-23
申请号：JP30252193
申请日：1993-12-02
申请人： HITACHI LTD
发明人： YOKOBAYASHI TOSHIAKI , NAKAGAWA MASAHITO , YAMAZAWA KAZUMASA
IPC分类号： H02P8/00 , H02P8/14
摘要： PURPOSE:To lift restrictions on the number of total pulses and to decrease the required number of RAMs per motor by calculating the pulse rates during acceleration and deceleration according to successive approximation equations. CONSTITUTION:Pulse rates are calculated during trapezoidal driving acceleration and deceleration according to equations. In the equations, alphau and alphad represent acceleration and deceleration, Rs represents an initial speed, Rc represents a maximum speed, Re represents a final speed, Pu represents the number of acceleration pulses and Pd represents the number of deceleration pulses. A step motor controller 1 is provided from a host CPU 5 with six driving parameters, i.e., an initial speed, a maximum speed, the number of maximum speed pulses and the number of deceleration pulses, which are stored a RAM 7. An acceleration is then calculated and stored in the RAM 7 and sequential pulses are generated at a rate according to the equations thus driving a step motor 3. This constitution allows generation of trapezoidal driving pulse using minimum number of RAMs per motor and the number is constant irrespective of the driving parameters.

26. 发明专利

JPH05142014A STABILIZING METHOD OF OPERATION OF CAPACITANCE TYPE LEVEL SENSOR 失效
公开(公告)号：JPH05142014A
公开(公告)日：1993-06-08
申请号：JP30153891
申请日：1991-11-18
申请人： HITACHI LTD
发明人： ISHIZAWA MASAHITO , YOKOBAYASHI TOSHIAKI
IPC分类号： G01F23/26
摘要： PURPOSE:To make it possible to detect reliably only the capacitance of a liquid in a liquid holding vessel and to detect reliably the level of the liquid in the vessel, without being affected by the noise propagated through a tube connected to a probe, by the floating capacity of the liquid in the tube, etc. CONSTITUTION:By providing an air gap 12 in a tube 6 inside a sampling arm, the value of the capacitance of a liquid in the tube 6 applied to a probe 2 is stabilized. In addition, the noise propagated through the liquid in the tube 6 is suppressed.

27. 发明专利

JPH04323564A SENSOR-INTEGRATED PROBE 失效
公开(公告)号：JPH04323564A
公开(公告)日：1992-11-12
申请号：JP9192891
申请日：1991-04-23
申请人： HITACHI LTD
发明人： ISHIZAWA MASAHITO , YOKOBAYASHI TOSHIAKI
IPC分类号： G01F23/26 , G01N35/10
摘要： PURPOSE:To surely detect only the electrostatic capacity of a liquid storage in a container so as to surely detect the level of the liquid inside the container. CONSTITUTION:A metallic tube 12 is mounted to a tube 6 located inside a sampling arm 1 and is connected to the ground so as to stabilize the value of the electrostatic capacity of a liquid inside the tube 6 and further to reduce noise transmitted through the liquid inside the tube 6, the electrostatic capacity being applied to a probe 2.

28. 发明专利

JPH02181652A IMAGE DISPLAY DEVICE OF AUTOMATIC BLOOD IMAGE CLASSIFYING DEVICE 失效
公开(公告)号：JPH02181652A
公开(公告)日：1990-07-16
申请号：JP31789
申请日：1989-01-06
申请人： HITACHI LTD
发明人： OWADA HAKUO , YOKOBAYASHI TOSHIAKI
IPC分类号： G01N33/48 , A61B5/00 , G01N21/27 , H04N7/18
摘要： PURPOSE:To inexpensively improve color reproducibility of images without having the need for separately setting the camera to be exclusively used for CRT display by subjecting the image signals obtd. by a TV camera for image processing to arithme tic processing in such a manner that the colors equal to real image colors are repro duced on the CRT. CONSTITUTION:The image information of a sample 1 magnified by a microscope 2 is passed through narrow-band filters FR, FG, FB 6 and is converted to electric signals R, G, B by a TV camera image pickup tube, by which the classification of blood cells is executed. These signals are passed through a mixing circuit 8 and a gammacorrecting circuit 8 and are thereby subjected to the correction of the color reproduc tion at the time of inputting the signals to the CRT. The mixing coefft. of the circuit 8 is so determined that the respective blood cell colors approximate uniformly to the real image colors. The magnitude of the gamma correction of the circuit 9 is so regulated with the circuit 8 that the contrast of the blood cell images is improved and the deterio ration of the color reproduction is obviated. The blood cell colors reproduced on the CRT are equaled to the color tones of the visual images by the microscope and the sense of incompatibility is eliminated by adding the circuits 8 and 9.

29. 发明专利

JPS6425691A COLOR SLIPPAGE CORRECTION CIRCUIT FOR COLOR TELEVISION CAMERA 失效
公开(公告)号：JPS6425691A
公开(公告)日：1989-01-27
申请号：JP18106387
申请日：1987-07-22
申请人： HITACHI LTD
发明人： YOKOBAYASHI TOSHIAKI , ABE TADASHI
IPC分类号： H04N9/093 , H04N9/64
摘要： PURPOSE:To correct color slippage by providing a time difference to the scanning start time of each image pickup element in response to the position deviation of images on R, G, B image pickup elements. CONSTITUTION:A scanning start signal from a synchronizing signal generating circuit 9 is fed to R, G, B solid-state image pickup elements 1, 2, 3 via R, G, B delay circuits 6, 7, 8. Then the deviation of image forming position among the solid-state image pickup elements l-3 is corrected and the color slippage is eliminated(however, an effective display region is reduced in overlapping images R, G, B). Then it is not required to align each image pickup element with high accuracy and the adjustment is facilitated. Outputs of the elements 1-3 are taken out as a color signal by a video processing circuit 11 and stored in a frame memory 13 via an AD conversion circuit 12. The picture data stored in the memory 13 is displayed on a display device 15 via a DA conversion circuit 14. A caption 10 is an address controller.

30. 发明专利

JPS6068725A ANALOG-DIGITAL CONVERTER 失效
公开(公告)号：JPS6068725A
公开(公告)日：1985-04-19
申请号：JP17621983
申请日：1983-09-26
申请人： HITACHI LTD
发明人： YOKOBAYASHI TOSHIAKI
IPC分类号： H03M1/10 , H03M1/12
摘要： PURPOSE:To improve the accuracy of A/D conversion by A/D-converting a reference signal from a reference signal generator, using the result, applying correcting operation to other A/D conversion output and using a conventional A/D converter. CONSTITUTION:An analog signal from sensors 11-1n is amplified respectively by signal amplifiers 21-2n and inputted to an analog switch section 3, and reference potentials E1, E2 from reference potential generators 4, 5 are also inputted to the analog switch section 3. The analog switch section 3 switches sequentially each input, the input is A/D-converted at an A/D converter 6 and the result is given to a data processing section 7. The data processing section 7 uses the result of A/D conversion of the reference potentials E1, E2, a gain correcting value and an offset correcting value of the A/D converter 6 are operated, this operation value is used, the result of A/D conversion from the sensor 11-1n is corrected and an output with high accuracy is obtained.

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