专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明专利

JP2003528057A 失效
公开(公告)号：JP2003528057A
公开(公告)日：2003-09-24
申请号：JP2001567726
申请日：2001-03-15
IPC分类号： A61K31/35 , A61K31/453 , A61P3/06 , A61P5/00 , A61P5/32 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P13/08 , A61P15/00 , A61P15/12 , A61P15/16 , A61P15/18 , A61P17/14 , A61P19/02 , A61P19/10 , A61P25/28 , A61P29/00 , A61P35/00 , C07D311/60

12. 发明专利

JP2003212771A ANTI-NEISSRIA BACTERIUM COMPOSITION 审中-公开
公开(公告)号：JP2003212771A
公开(公告)日：2003-07-30
申请号：JP2002014242
申请日：2002-01-23
申请人： TAIYO KAGAKU KK , NAT CANCER CT JAPAN
发明人： OKUBO TSUTOMU , MUTO MANABU , ESUMI HIROYASU , REKA RAJU JUNEJA
IPC分类号： C07D311/60 , A61K31/353 , A61K36/18 , A61P31/04 , A61P35/00 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To provide an anti-Neisseria bacterium composition which can sterilize Neisseria bacterium in oral cavities and is safe and simple. SOLUTION: Tea powder or tea extract contains one or more substances selected from the group consisting of (+)-catechin, (-)-epicatechin, (+)- gallocatechin, (-)-epigallocatechin, (-)-catechin gallate, (-)-epicatechin gallate, (-)-gallocatechin gallate, (-)-epigallocatechin gallate, free theaflavin, theaflavin monogallate A, theaflavin monogallate B and theaflavin digallate. A composition containing the substance exhibits a strong antibacterial action against Neisseria bacterium which is one of bacteria in oral cavities. COPYRIGHT: (C)2003,JPO

13. 发明专利

JP2002145773A METHOD AND KIT FOR AMELIORATING VASCULAR HEALTH CONDITION 审中-公开
公开(公告)号：JP2002145773A
公开(公告)日：2002-05-22
申请号：JP2001317833
申请日：2001-10-16
申请人： PFIZER PROD INC
发明人： DAY WESLEY WARREN , LEE ANDREW G , THOMPSON DAVID DUANE
IPC分类号： C07D295/08 , A61K31/00 , A61K31/352 , A61K31/40 , A61K31/404 , A61K31/4439 , A61K31/47 , A61K31/4709 , A61K31/506 , A61K31/517 , A61P3/06 , A61P9/00 , A61P9/10 , A61P13/12 , A61P15/00 , A61P25/04 , A61P25/08 , A61P35/00 , A61P43/00 , C07D209/12 , C07D311/60
摘要： PROBLEM TO BE SOLVED: To provide a method for preventing myocardial infarction or stroke, maintaining or ameliorating vascular reactivity, treating acute or chronic renal failure, peripheral arterial occlusive diseases, coronary artery diseases or Raynaud's phenomenon or lowering plasma levels of Lp(a). SOLUTION: The method and kit for ameliorating or maintaining vascular health conditions include preventing the myocardial infarction or stroke, maintaining or ameliorating the vascular reactivity, treating the acute or chronic renal failure, peripheral arterial occlusive diseases, coronary artery diseases or Raynaud's phenomenon or lowering plasma levels of Lp(a) and uses an estrogen/antagonist.

14. 发明专利

JP2002068939A COMPOSITION FOR COLORING SKIN INCLUDING FLAVYLIUM SALT HAVING UNSUBSTITUTED 3 POSITION AND USE OF THE SAME 审中-公开
公开(公告)号：JP2002068939A
公开(公告)日：2002-03-08
申请号：JP2001212783
申请日：2001-07-12
申请人： OREAL
发明人： CANDAU DIDIER , FORESTIER SERGE
IPC分类号： C07D311/60 , A61K8/00 , A61K8/49 , A61K8/97 , A61K31/353 , A61K36/18 , A61K36/899 , A61P17/00 , A61Q1/02 , A61Q19/04 , A61K7/021 , A61K35/78
摘要： PROBLEM TO BE SOLVED: To obtain a composition capable of imparting a color to the skin which resembles the color of natural suntanned skin by a simple, effective and rapid process free from danger. SOLUTION: This composition includes, on a cosmetically permissible carrier, at least one flavylium salt compound having at least one hydroxyl or alkoxy substituting group and no substituent at the 3 position, obtained from an extract of a plant or a concentrated plant extract thereof including the compound or by synthesis, in an effective amount capable of obtaining a dark color tone ΔL* of -0.5 to -20 in an L*a*b* coloriemetric determination method 30 min after applying to the white skin in a rate of 2 mg/cm2.

15. 发明专利

JP2000186083A PRODUCTION OF SIDEROXYLONALS 失效
公开(公告)号：JP2000186083A
公开(公告)日：2000-07-04
申请号：JP4422099
申请日：1999-02-23
申请人： NISSAN CHEMICAL IND LTD
发明人： TATSUTA KUNIAKI
IPC分类号： C07D311/60 , A01N43/16 , A61K31/00 , A61K31/35 , A61K31/352 , A61K31/353 , A61P3/00 , A61P3/10 , A61P31/00 , A61P31/04 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To synthesize the subject compounds having useful activities such as an inhibiting activity against aldose reductases, an antimicrobial activity or a preventing activity against the attachment of underwater organisms by eliminating substituent groups of a dihydrobenzopyran derivative. SOLUTION: Substituent groups R of a dihydrobenzopyran derivative represented by formula I (Rs are each a protecting group of hydroxy group and preferably methyl group) are eliminated to thereby produce the objective compounds represented by formula II. For example, when Rs are each methyl group, a method for reacting Me3SiI in chloroform solvent at 25-50 deg.C for 12-140 h is cited as the method for eliminating the substituent groups R. The compound represented by formula I is prepared by heating, e.g. a phenol represented by formula III in the presence of a Grignard reagent, providing a compound represented by formula IV, introducing the protecting groups R, then reacting the resultant compound with a brominating agent, lithiating the resultant compound with t-BuLi, subsequently introducing carboxyl groups with CO2, methyl etherifying the prepared compound with TMSCHN2, reducing the obtained compound and then oxidizing the reduction product.

16. 发明专利

JP2000109473A NEW FLAVAN DERIVATIVE, ITS PRODUCTION AND COSMETIC CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT 失效
公开(公告)号：JP2000109473A
公开(公告)日：2000-04-18
申请号：JP28306698
申请日：1998-10-05
申请人： MITSUI CHEMICALS INC
发明人： NAGATOMO AKINORI , WADA MASARU
IPC分类号： C07D311/60 , A61K8/00 , A61K8/33 , A61K8/49 , A61Q17/04 , A61Q19/00 , A61Q19/02 , C07C43/23 , A61K7/00 , A61K7/42 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To obtain a new flavan derivative having excellent pigmentation- inhibiting effect, excellent beautifully whitening effect, high skin safety and storage stability and useful as an active ingredient for cosmetics. SOLUTION: A compound of formula I (R1 to R3 are each H, a 1-20C alkyl, an alkenyl or the like), preferably 2-(2,4-dihydroxyphenyl)-7-hydroxychroman. The compound of formula I is obtained by catalytically hydrogenating a hydrochalcone derivative of formula II (R4 to R7 are each H, a 1-20C alkyl, an alkenyl or the like) [for example, 1,3-bis(2,4-dibenzyloxyphenyl)-3-hydroxy-1- propene] in a solvent such as methanol usually at 0-100 deg.C under the atmospheric pressure to 1 MPa.G, for example, by a method for bringing the compound of formula II into contact with hydrogen in the presence of a catalyst such as Pd/C, and subsequently removing protecting groups.

17. 发明专利

JP2657518B2 失效
公开(公告)号：JP2657518B2
公开(公告)日：1997-09-24
申请号：JP13725888
申请日：1988-06-06
申请人： KONIKA KK
发明人： SUGITA SHUICHI , KANEKO YUTAKA , MIZUKURA NOBORU , KITA HIROSHI , IKESU SATORU
IPC分类号： G03C7/26 , C07D307/83 , C07D311/58 , C07D311/60 , C07D319/08 , C07D493/04 , C08K5/1575 , C09K15/06 , G03C7/392 , C08K5/15

18. 发明专利

JP2609122B2 失效
公开(公告)号：JP2609122B2
公开(公告)日：1997-05-14
申请号：JP32077187
申请日：1987-12-18
IPC分类号： C07D231/46 , C07D239/54 , C07D261/12 , C07D261/20 , C07D265/06 , C07D291/04 , C07D307/58 , C07D311/60 , C07D327/04 , C07D403/12 , C07D405/12 , C07D413/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D419/12 , C07D487/04 , C07D521/00 , G03C7/26 , G03C7/305

20. 发明专利

JPH08500127A 失效
公开(公告)号：JPH08500127A
公开(公告)日：1996-01-09
申请号：JP50142295
申请日：1994-06-10
IPC分类号： A61K8/00 , A61K8/25 , A61K8/44 , A61K8/49 , A61K8/67 , A61K8/73 , A61K8/92 , A61K8/97 , A61Q1/00 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/12 , A61Q3/02 , A61Q5/10 , A61Q7/00 , A61Q19/04 , C07D311/60 , C09B57/00 , C09B61/00 , C12P17/06 , C12R1/91 , A61K7/00

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式