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1. 发明专利

JP2004026677A Skin care preparation for applying to skin 审中-公开
公开(公告)号：JP2004026677A
公开(公告)日：2004-01-29
申请号：JP2002182217
申请日：2002-06-21
申请人： Lion Corp , ライオン株式会社
发明人： HAYASHI HIROYUKI , ITO SEIJI
IPC分类号： A61K9/10 , A61K8/00 , A61K8/02 , A61K8/92 , A61M35/00 , A61Q19/00 , A61K7/48 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To provide a skin care preparation readily extending on an affected part with a suitable amount of discharge and having a good feeling of use with an excellent dry feeling and lubricity without greasiness irrespective of an oily preparation, in the oily skin care preparation for applying to the skin having excellent percutaneous absorption. SOLUTION: This preparation is obtained by storing an oily external preparation composition prepared by formulating an oil having ≤100 cSt viscosity at 40°C and powder particles in the following application container (A) or (B).(A) an application container having a rotatable spherical or a rotatable roller-shaped application part or (B) an application container having an application part which is a soft porous material. COPYRIGHT: (C)2004,JPO

2. 发明专利

JP2008154810A Ophthalmic agent 审中-公开
标题翻译： OPHTHALMIC代理
公开(公告)号：JP2008154810A
公开(公告)日：2008-07-10
申请号：JP2006347299
申请日：2006-12-25
申请人： Lion Corp , ライオン株式会社
发明人： ITO SEIJI , SHIMOGAKI HISAO
IPC分类号： A61J1/00 , A61K9/08 , A61K31/4375 , A61P27/02
摘要： PROBLEM TO BE SOLVED: To provide an ophthalmic agent containing a medicine unstable under light, especially berberine, and exerting favorable stability of the medicine.
SOLUTION: This ophthalmic agent is formed by filling a resin container with absorbance of 0.5 or more at wavelength 400 nm or less with ophthalmic components containing the medicine unstable under the light. It is preferable to use a resin container with the absorbance of 1.0 or less at the wavelength of 600 nm.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供含有在光下特别是小檗碱不稳定的药物的眼药，并赋予药物良好的稳定性。解决方案：该眼用试剂通过在波长400nm以下的吸收度为0.5以上的树脂容器填充含有药剂在光下不稳定的眼部成分而形成。优选使用波长600nm的吸光度为1.0以下的树脂容器。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2008009145A Contact lens cleaning composition, and contact lens cleaning method 审中-公开
标题翻译：接触透镜清洁组合物和接触透镜清洗方法
公开(公告)号：JP2008009145A
公开(公告)日：2008-01-17
申请号：JP2006179781
申请日：2006-06-29
申请人： Lion Corp , ライオン株式会社
发明人： HATTORI MANABU , ITO SEIJI
IPC分类号： G02C13/00 , C11D3/06 , C11D3/22 , C11D3/37 , C11D3/48 , C11D17/00
摘要： PROBLEM TO BE SOLVED: To provide a contact lens cleaning composition by which a contact lens is easily scrubbed with less friction at scrubbing, and to prevent the breakage of a soft contact lens due to scrubbing, and to surely scrub all kinds of contact lenses.
SOLUTION: The contact lens cleaning composition contains (A) a polyvinyl-based water-soluble high polymer compound and (B) a compound selected out of mucopolysaccharides, mucopolysaccharide salt, polyphosphoric acid and polyphosphate.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种隐形眼镜清洁组合物，通过该隐形眼镜清洁组合物，可以在擦洗时以较少的摩擦容易地擦洗隐形眼镜，并且防止由于擦洗而导致的软性隐形眼镜的破裂，并且可靠地擦洗各种隐形眼镜。解决方案：隐形眼镜清洁组合物含有（A）聚乙烯基水溶性高分子化合物和（B）选自粘多糖，粘多糖盐，多磷酸和多磷酸盐的化合物。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2007039661A Polymer compound and composition for contact lens 有权
标题翻译：聚合物化合物和接触镜片的组合物
公开(公告)号：JP2007039661A
公开(公告)日：2007-02-15
申请号：JP2006172184
申请日：2006-06-22
申请人： Lion Corp , ライオン株式会社
发明人： SHIMIZU YOSHIO , HARA YUSUKE , TOKI IKUKO , KOMATSU MASANORI , HATTORI MANABU , ITO SEIJI
IPC分类号： C08F226/10 , C08F220/34 , G02C7/04
摘要： PROBLEM TO BE SOLVED: To provide a polymer compound and a composition for contact lenses, holding lens shape, easy for wearing and maintaining comfortable wear feeling. SOLUTION: This polymer compound is obtained by copolymerizing a monomer mixture containing each specific amounts of (A) monomer, (B) monomer, (C) monomer and (D) monomer. (A) A monomer having a tertiary amino group and expressed by general formula (1) [wherein, R 1 is H or methyl; A is O or NH; R 2 , R 3 are each H or an alkyl; R 4 , R 5 are each an alkyl; and (m) is 0, 1 or 2], (B) N-vinyl-2-pyrrolidone, (C) (meth)acrylic acid ester monomer, and (D) a nonionic water-soluble monomer other than the (A) to (C). COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种高分子化合物和隐形眼镜用组合物，保持透镜形状，容易佩戴并保持舒适的穿着感。（A）单体，（B）单体，（C）单体和（D）单体的单体混合物共聚得到该高分子化合物。（A）具有叔氨基并由通式（1）表示的单体[其中，R 1 = H或甲基; A是O或NH; R 2 SP 3，R 3 SP 3各自为H或烷基; R SP 3，R 6，R 6，R 5，和（m）为0,1或2]，（B）N-乙烯基-2-吡咯烷酮，（C）（甲基）丙烯酸酯单体和（D）非（A）至（C）。版权所有（C）2007，JPO＆INPIT

5. 发明专利

JP2005208628A Precare agent for contact lens and precare method of contact lens 审中-公开
标题翻译：接触透镜的预备剂和接触镜的预处理方法
公开(公告)号：JP2005208628A
公开(公告)日：2005-08-04
申请号：JP2004375457
申请日：2004-12-27
申请人： Lion Corp , ライオン株式会社
发明人： ITO SEIJI , HATTORI MANABU , SHIMOGAKI HISAO , SHIMIZU YOSHIO , HARA YUSUKE
IPC分类号： G02C13/00
摘要： PROBLEM TO BE SOLVED: To provide a precare agent composition for contact lenses which prevents the adhesion of smudge, such as protein, to the lenses arising during wearing of the contact lenses, imparts the feel of dampness to the lenses, and suppresses the degradation in the feel of wearing, such as the dryness of the eyes, and a precare method.
SOLUTION: The precare agent for contact lenses contains (A) a monomer having an amino group and/or a monomer having a quaternary ammonium group, (B) (meth)acrylate monomer, (C) a vinyl lactam monomer, and (D) a polymer compound prepared by copolymerizing one or two or more nonionic hydrophilic monomers exclusive of the aforementioned (A), (B) and (C) at specific ratios.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了提供一种防止隐形眼镜佩戴期间产生的诸如蛋白质等污迹的隐形眼镜预防剂组合物，赋予镜片湿润感，并抑制穿着感的降低，如眼睛的干燥，以及预防方法。解决方案：隐形眼镜预处理剂含有（A）具有氨基的单体和/或具有季铵基团的单体，（B）（甲基）丙烯酸酯单体，（C）乙烯基内酰胺单体和（D）以特定比例将不同于上述（A），（B）和（C）的一种或两种以上非离子亲水性单体进行共聚制备的高分子化合物。版权所有（C）2005，JPO＆NCIPI

6. 发明专利

JP2011037840A Orodispersible tablet and process for manufacturing the same 有权
标题翻译： ORPDISPERSIBLE TABLET AND PROCESS FOR MANUFACTURING THE SAME
公开(公告)号：JP2011037840A
公开(公告)日：2011-02-24
申请号：JP2010159874
申请日：2010-07-14
申请人： Lion Corp , ライオン株式会社
发明人： MATSUMOTO NAOKO , NAGASHIMA SHINICHI , ITO SEIJI
IPC分类号： A61K9/20 , A61K47/26 , A61K47/38
摘要： PROBLEM TO BE SOLVED: To provide an orodispersible tablet excellent in formability and disintegration ability as an orodispersible tablet and a process for manufacturing the same.
SOLUTION: The orodispersible tablet include granulated drug particles. The granulated drug particle is obtained by adding an aqueous solution containing a monosaccharide to the powder containing a drug and wet-granulating the powder.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供作为可分散片剂的成形性和崩解性优异的可分散片剂及其制造方法。解决方案：可分散片剂包括颗粒状药物颗粒。通过向含有药物的粉末中加入含有单糖的水溶液，对该粉末进行湿式造粒，得到粒状药物粒子。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2006003827A Water film forming agent for contact lens and composition containing same 有权
标题翻译：用于接触镜片的水膜成型剂及其组合物
公开(公告)号：JP2006003827A
公开(公告)日：2006-01-05
申请号：JP2004182782
申请日：2004-06-21
申请人： Lion Corp , ライオン株式会社
发明人： HATTORI MANABU , ITO SEIJI , SHIMIZU YOSHIO , HARA YUSUKE
IPC分类号： G02C13/00 , A01N61/00 , C09K3/00
摘要： PROBLEM TO BE SOLVED: To provide a water film forming agent for a contact lens, an ophthalmologic composition which contains the same and by which a good field of view and wearing feel can be obtained, and a composition for the contact lens.
SOLUTION: The water film forming agent for the contact lens is composed of a copolymer containing the following (A) and (B): (A) the hydrophobic monomer having a polymerizable unsaturated double bond; (B) the hydrophilic monomer having the polymerizable unsaturated double bond. The water film forming agent for the contact lens, the ophthalmologic composition which is compounded therewith and by which the good field of view and wearing feel can be obtained, and the composition for the contact lens can thus be obtained.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供一种用于隐形眼镜的水膜形成剂，可以获得含有该成膜剂并且具有良好的视野和佩戴感觉的眼科组合物和用于隐形眼镜的组合物。解决方案：隐形眼镜用水成膜剂由含有下述（A）和（B）的共聚物构成：（A）具有聚合性不饱和双键的疏水性单体; （B）具有聚合性不饱和双键的亲水性单体。用于隐形眼镜的水膜形成剂，与其混合并可以获得良好的视野和佩戴感觉的眼科组合物，从而可以获得隐形眼镜的组合物。版权所有（C）2006，JPO＆NCIPI

8. 发明专利

JP2004359947A Polymer compound for preventing adhesion of protein and composition containing the same 有权
公开(公告)号：JP2004359947A
公开(公告)日：2004-12-24
申请号：JP2004143177
申请日：2004-05-13
申请人： Lion Corp , ライオン株式会社
发明人： HARA YUSUKE , SHIMIZU YOSHIO , KOMATSU MASANORI , ITO SEIJI , HATTORI MANABU
IPC分类号： G02C13/00 , A61K8/00 , A61Q5/02 , C08F220/18 , A61K7/075
摘要： PROBLEM TO BE SOLVED: To provide a polymer compound for preventing adhesion of a protein, having excellent ability of preventing the adhesion of the protein to a rigid surface of glass, ceramic, stainless steel, plastic, etc., a soft surface of the hair, a fiber, etc., a gel surface, a surface of a contact lens, etc., which is used as a material for a medical device, etc., and feared that biocompatibility of the material may be deteriorated by the adhesion of a substance derived from an organism, even when the surface is treated with the compound of a low concentration in a short time, and excellent in durability of the ability.
SOLUTION: This polymer compound for preventing the adhesion of the protein is given by copolymerizing (A) a monomer expressed by formula (1) (R
1 is H or methyl; A is O or NH; R
2 and R
3 are each H or an alkyl; R
4 and R
5 are each an alkyl; and m is 0, 1 or 2) and/or a monomer expressed by formula (2) (R
6 is H or methyl; A is O or NH; R
7 and R
8 are each H or an alkyl; R
9 , R
10 and R
11 are each an alkyl; X is a halogen; and n is 0, 1 or 2), (B) a monomer expressed by formula (3): CH
2 =C(R
12 )COOR
13 (R
12 is H or methyl; and R
13 is an alkyl), and (C) a nonionic water-soluble monomer.
COPYRIGHT: (C)2005,JPO&NCIPI

9. 发明专利

JP2004210727A Oily gel composition and oily pharmaceutical preparation composition for external use 审中-公开
标题翻译：油性组合物和油用于外用的药物制剂组合物
公开(公告)号：JP2004210727A
公开(公告)日：2004-07-29
申请号：JP2002383841
申请日：2002-12-28
申请人： Lion Corp , ライオン株式会社
发明人： ITO SEIJI , HAYASHI HIROYUKI
IPC分类号： A61K47/06 , A61K9/06 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/34
摘要： PROBLEM TO BE SOLVED: To obtain an oily gel composition satisfying good feelings upon use, adequate viscosity, long-term stability and transparency and an oily pharmaceutical preparation composition for external use having high effectiveness and excellent in feelings upon use and stability.
SOLUTION: The oily gel composition comprises (a) a liquid hydrocarbon oil having ≤40°C coagulation point, (b) a metallic soap and (c) a lipophilic surfactant having an unsaturated and/or branched alkyl chain and having 1-8 HLB.
COPYRIGHT: (C)2004,JPO&NCIPI

10. 发明专利

JP2001122769A SOLID PREPARATION AND METHOD FOR IMPROVING DISINTEGRATION/DISSOLUTION OF SOLID PREPARATION 失效
公开(公告)号：JP2001122769A
公开(公告)日：2001-05-08
申请号：JP30167899
申请日：1999-10-22
申请人： LION CORP
发明人： YANASE TOMIYUKI , OBAYASHI YOSHIYUKI , ITO SEIJI , UEDA SHUICHI
IPC分类号： A61K9/20 , A61K47/00
摘要： PROBLEM TO BE SOLVED: To improve disintegration of a solid preparation and dissolution of a medicine having

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