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1. 发明授权

EP3265447B1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION 有权
公开(公告)号：EP3265447B1
公开(公告)日：2023-03-01
申请号：EP16759547.9
申请日：2016-03-04
发明人： WANG, Dong , RECHICHAR, Bradley , KINCAID, Derek S. , SMITH, Ronald C.
IPC分类号： C07D265/14 , C07D265/16 , C08G73/06 , C08G73/22

2. 发明授权

EP3323813B1 HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF 有权
公开(公告)号：EP3323813B1
公开(公告)日：2020-08-26
申请号：EP17207865.1
申请日：2011-12-22
申请人： The Trustees of Columbia University in the City of New York
发明人： Francis, Yitshak , Fa, Mauro , Arancio, Ottavio , Fiorito, Jole , Deng, Shixian , Landry, Donald W. , Luzac, Michal , Feng, Yan
IPC分类号： C07D265/14 , C07C217/22 , C07C217/58 , C07C235/60 , C07C235/64 , C07D265/36 , C07C251/24 , C07D209/48 , C07D295/088 , A61K31/167 , A61P25/28

3. 发明公开

EP3395804A1 NOVEL SPIROQUINONE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS WHICH CONTAINS SAME AS ACTIVE INGREDIENT 有权
公开(公告)号：EP3395804A1
公开(公告)日：2018-10-31
申请号：EP17849145.2
申请日：2017-09-08
申请人： Gachon University of Industry-Academic Cooperation Foundation , Gil Medical Center
发明人： KIM, Mi-hyun , KIM, Sun Yeou , LEE, Sang-Yoon , ARRAMSHETTI, Venkanna , KIM, Kang , CHO, Kyohee , LAMA, Prema Dhorma
IPC分类号： C07D265/14 , A61K31/537 , A23L33/10
摘要： The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredient, and it has been confirmed that the novel spiroquinone derivative compound according to the present invention, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof may excellently suppress 'microglial activation' and shows excellent inhibition activity against acetylcholinesterase, JNK1, JNK2 and JNK3, and in addition to this, significant enzyme inhibition activity has been confirmed in a neurological diseases-related enzyme group, RIPK5, CDK3/cyclin E, PKN2/PRK2, Haspin, STK25/YSK1, ARK5/NUAK1, PKCb2, CDK2/cyclin O, DAPK1, PKCa, CDK1/cyclin B, MST3/STK24 and TLK1 and it has been confirmed that cell death suppression effect may be exhibited, and thus the novel spiroquinone derivative compound according to the present invention, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof can be usefully used for a pharmaceutical composition for preventing or treating neurological disorders or health functional food composition for preventing or improving neurological disorders by being contained therein as an active ingredient.

4. 发明授权

EP1314755B1 Ultraviolet radiation absorbents for thermoplastic polymers and methods of producing the same 有权
标题翻译：对于它们的制备热塑性聚合物和方法紫外线吸收剂
公开(公告)号：EP1314755B1
公开(公告)日：2010-09-08
申请号：EP02258010.4
申请日：2002-11-20
申请人： Takemoto Yushi Kabushiki Kaisha , Teijin Dupont Films Japan Limited
发明人： Osaki, Tatsuhiko, c/o Takemoto Yushi , Ichihashi, Tetsuo, c/o Teijin DuPont Films
IPC分类号： C08K5/357 , C07D265/14
CPC分类号： C07D265/14 , C08K5/357

5. 发明授权

EP1366053B1 FLAME-PROOFING AGENTS 有权
标题翻译：手段的闪存保护
公开(公告)号：EP1366053B1
公开(公告)日：2005-01-05
申请号：EP01273295.4
申请日：2001-11-20
申请人： Huntsman Advanced Materials (Switzerland) GmbH
发明人： WEIDMANN, Ulrich , MAGENDIE, Franck
IPC分类号： C07F9/6571 , C07D265/14 , C07D265/20 , C08K5/00
CPC分类号： C08K5/5313 , C07F9/657172
摘要： Compounds of formula (I) or (II), wherein R1 is C1-C18alkyl; C5-C12cycloalkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; C5-C22aryl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; or C7-C30aralkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups, and the radicals R2 to R13 are each independently of the others hydrogen; -NO2; dialkylamino; alkylthio; alkylsulfonyl; halogen; C1-C18alkyl; C1-C18alkoxy; C1-C18alkoxyalkyl; C5-C12cycloalkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; C5-C22aryl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; or C7-C30aralkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups, are suitable as flame-proofing agents for thermoplastic or thermosetting polymers.

6. 发明公开

EP0187329A1 Chromogene 3,1-Benzoxazine 失效
标题翻译：染色体3,1-苯并恶嗪。
公开(公告)号：EP0187329A1
公开(公告)日：1986-07-16
申请号：EP85116194.3
申请日：1985-12-18
申请人： BAYER AG
发明人： Berneth, Horst, Dr.
IPC分类号： B41M5/12 , C07D265/14 , C07D413/04 , C07D413/06 , C07D413/10 , C07D413/14 , C07C103/30
CPC分类号： C09B11/04 , B41M5/136 , B41M5/323 , C07D265/16 , C07D413/04 , C09B11/02
摘要： Als Farbbildner für druck-, wärme- und elektrosensitive Aufzeichnungsmaterialien mit saurem Entwickler eignen sich hervorragend Verbindungen der Formel
worin Z 1 Wasserstoff, Alkyl, Cycloalkyl oder
R 1 Wasserstoff, Alkyl, Cycloalkyl, Aralkyl, Aryl, Heteroalkyl oder Heteryl, X 1 , X 2 und X 3 Wasserstoff, Halogen, Alkyl, Cycloalkyl, Aryl, Alkanoylamino, Aroylamino, Heteryl und wenigstens einer dieser Reste NY 1 Y 2 , OY 3 oder SY 3 , Y', Y 2 und Y 3 Wasserstoff, Alkyl, Cycloalkyl, Aralkyl, Aryl oder Heteryl und Y 1 + Y 2 die restlichen Glieder eines gegebenenfalls weitere Heteroatome enthaltenden 5- oder 6-gliedrigen Ringes bedeuten. Man erhält farbstarke und lichtechte Kopien.
摘要翻译：正如前对压力 - ，热和电敏记录材料的彩色与下式的酸性显影剂特别适合的化合物其中Z是氢，烷基，环烷基，或 R是氢，烷基，环烷基，芳烷基。芳基，杂烷基或heteryl，X 1，X 2和X 3是氢，卤素，烷基，环烷基，芳基，烷酰基氨基，芳酰基氨基，heteryl，和这些基团NY¹Y²，OY³或SY³，Y 1，Y 2和中的至少一个Y 3是氢，烷基，环烷基，芳烷基，芳基或heteryl Y 1和Y +任选含有另外的杂原子的其余成员意味着5-或6-元环。产生强烈的光 - 快速复制。

7. 发明公开

EP3362439A1 BIOMASS-DERIVED POLYMERS AND COPOLYMERS INCORPORATING MONOLIGNOLS AND THEIR DERIVATIVES 审中-实审
公开(公告)号：EP3362439A1
公开(公告)日：2018-08-22
申请号：EP16856362.5
申请日：2016-10-14
申请人： The Regents of the University of California
发明人： UPTON, Brianna Marie , KASKO, Andrea
IPC分类号： C07D265/14 , C08G63/44 , C08G69/04 , C08G69/40 , C08G73/02
CPC分类号： C07D265/16 , C07C51/09 , C07C67/14 , C07C67/28 , C07C67/31 , C07C67/343 , C08G69/40 , C08G69/44 , C08G73/0233 , C07C69/732 , C07C69/734 , C07C69/73 , C07C69/44 , C07C59/64
摘要： The invention includes methods and materials for forming and manipulating aromatic-based polymers and copolymers using biomass compounds as starting materials. Embodiments of the invention can be used in processes designed to replace those used in the petrochemical industry. Typical embodiments of the invention include methods and materials for forming and/or modifying compounds including dicarboxylic acid ester dimers, benzoxazines and dicarboxylic acid ether dimers. Embodiments of the invention further provide methods and materials for utilizing these compounds to form commercially desirable polymers having structures and physical properties akin to those found in polymers formed from petroleum products.

8. 发明公开

EP2831052A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME 有权
标题翻译：苯并恶嗪和SO组合物
公开(公告)号：EP2831052A1
公开(公告)日：2015-02-04
申请号：EP13713697.4
申请日：2013-03-19
申请人： Cytec Technology Corp.
发明人： WARD, Steven, Richard , HARRIMAN, Mark, Edward
IPC分类号： C07D265/14 , C08K5/357 , C08J5/24 , C07D265/16
CPC分类号： C08G73/0233 , C07D265/16 , C08G14/06 , C08G59/00 , C08J5/24 , C08K5/357 , C08L61/34 , C08L79/02
摘要： Disclosed herein are monofunctional benzoxazine compounds having at least one electron-withdrawing group. The monofunctional benzoxazine compounds may be combined with one or more multifunctional benzoxazine compounds to form a unique benzoxazine blend. This benzoxazine blend may be combined with additional components such as catalysts and toughening agents to form a curable resin composition suitable for forming resinous films or composite materials. The presence of monofunctional benzoxazine improves the processability of the benzoxazine-based resin composition by reducing the viscosity of the resin composition, and results in improved tack and drape in the films and composite materials formed from the composition without the loss of modulus in the cured resin.

9. 发明授权

EP1874743B1 PURIFIED FORM OF TANAPROGET 有权
标题翻译： TANAPROGET的净化形式
公开(公告)号：EP1874743B1
公开(公告)日：2013-07-17
申请号：EP06769890.2
申请日：2006-04-26
申请人： Wyeth LLC
发明人： CHATLAPALLI, Ramarao , NAGI, Arwinder , POTOSKI, John , HELOM, Jean, Louise , WILK, Bogdan, Kazimierz , RUBEZHOV, Arkadiy, Zinoviy , DRAGAN, Vladimir
IPC分类号： C07D265/14 , C07D413/04 , A61K31/536 , A61P15/00
CPC分类号： C07D265/14 , C07D413/04

10. 发明公开

EP1948623A2 HETEROCYCLIC AMIDE DERIVATIVES AS RXR AGONISTS FOR THE TREATMENT OF DYSLIPIDEMIA, HYPERCHOLESTEROLEMIA AND DIABETES 审中-公开
标题翻译： AS RXR激动剂杂环酰胺衍生物FOR血脂异常，高胆固醇血症和糖尿病治疗
公开(公告)号：EP1948623A2
公开(公告)日：2008-07-30
申请号：EP06804129.2
申请日：2006-09-25
申请人： Janssen Pharmaceutica, N.V.
发明人： BHARAT, Lagu , LEBEDEV, Rimma , PIO, Barbara
IPC分类号： C07D241/44 , C07D265/14 , C07D265/36 , A61K31/538 , A61K31/536 , A61K31/498 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P29/00 , A61P35/00
CPC分类号： C07D265/14 , C07D241/44 , C07D265/12 , C07D265/36
摘要： The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating RXR mediated disorders. More particularly, the compounds of the present invention are RXR agonists useful for treating RXR mediated disorders.

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