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    • 10. 发明公开
    • Fungicidal pyridazines
    • 氟啶哒嗪。
    • EP0208431A1
    • 1987-01-14
    • EP86304521.7
    • 1986-06-12
    • ELI LILLY AND COMPANY
    • Dow, William ClintonJohnson, George WilliamArnold, Wendell Ray
    • A01N43/58A01N47/14A01N55/00A01N55/02C07F7/10C07D237/10C07D237/12
    • C07D405/12A01N43/56A01N55/00C07D237/08C07D237/12C07D237/24C07F7/0814
    • Plants are protected from the damaging effects of Phycomycetous fungi by a series of pyridazines having halo-branched-alkyl or halo-branched-alkyl-silyl groups. The pyridazines have the formula
      wherein

      R 3 is chloro, bromo, methyl, cyano or iodo;
      R is chloro, bromo, iodo, methyl, cyano or furan-2- rlmethoxy;
      R' is hydrogen, methyl, ethyl or n-propyl;
      R 2 is


      X is fluoro, chloro, bromo or iodo;
      X' and X 2 independently represent X or hydrogen, provided that no more than one of X 1 and X 2 is hydrogen; ,
      R 4 is hydrogen, chloro, bromo, methyl or ethyl;
      R 5 is hydrogen, chloro, methyl, ethyl, chloromethyl or dichloromethyl;

      or

      R 4 and R 5 combine with the group to which they are attached to form a C 3 -C 7 cycloalkyl group substituted with a R 1 group;
      R 6 is hydrogen, chloro, bromo, methyl or ethyl;
      R 7 is hydrogen, methyl, ethyl, chloromethyl or dichloromethyl;
      one of m and n is 0 or 1, and the other is 0;
      p is 0-4.
    • 通过一系列具有卤代支链 - 烷基或卤代支链烷基 - 甲硅烷基的哒嗪,保护植物免受植物疫霉真菌的破坏作用。 哒嗪类具有式CHEM,其中R 3为氯,溴,甲基,氰基或碘; R是氯,溴,碘,甲基,氰基或呋喃-2-基甲氧基; R 1是氢,甲基,乙基或正丙基; R 2是 X是氟,氯,溴或碘; X 1和X 2独立地表示X或氢,条件是X 1和X 2中不超过一个是氢; R 4是氢,氯,溴,甲基或乙基; R 5是氢,氯,甲基,乙基,氯甲基或二氯甲基; 或R 4和R 5与它们所连接的基团结合形成被R 1基团取代的C 3 -C 7环烷基; R 6是氢,氯,溴,甲基或乙基; R 7是氢,甲基,乙基,氯甲基或二氯甲基; 一个或m和n是0或1,另一个是0; p为0-4。 小号