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    • 1. 发明公开
    • ADSORBENTS FOR ORAL ADMINISTRATION
    • ADSORBENTIEN ZUR ORALEN VERABREICHUNG
    • EP1547605A4
    • 2005-11-02
    • EP03770094
    • 2003-10-31
    • KUREHA CHEMICAL IND CO LTD
    • SONOBE NMORIMOTO SYOSHIHARA HHANATSUKA HARAKAWA M
    • A61K33/44A61P1/16A61P13/12A61P39/02
    • A61K33/44
    • An adsorbent for oral administration characterized by comprising a spherical active carbon which has a diameter of from 0.01 to 1 mm, a specific surface area determined in accordance with Langmuir's adsorption equation of 1000 m /g or more, and a diffraction intensity ratio (R) determined by the following formula (1) of 1.4 or more: R=(I15-I35)/(I24-I35) (1) wherein I15, I35 and I24 respectively represent diffraction intensities at diffraction angles (2theta) 15°, 35°and 24°determined by the X-ray diffractometry. An adsorbent for oral administration characterized by comprising a surface-modified spherical active carbon which has a diameter, a specific surface area and a diffraction intensity ratio (R) each falling within the range as specified above and carries 0.40 to 1.00 meq/g of acidic groups in total and 0.40 to 1.10 meq/g of basic groups in total. These adsorbents for oral administration scarcely adsorb useful components in vivo and have favorable performance of adsorbing toxic substances, i.e., showing advantageous selective adsorption properties.
    • 一种口服给药用吸附剂,其特征在于,含有直径为0.01〜1mm的球形活性炭,根据朗缪尔吸附方程确定的比表面积为1000m 2 / g或更高,并且衍射强度比 (1)确定的下式(R)为1.4以上:R =(I15-I35)/(I24-I35)(1)其中I15,I35和I24分别表示衍射角(2θ)15° ,35°和24°由X射线衍射测定。 一种口服给药用吸附剂,其特征在于,含有表面改性球形活性炭,其直径,比表面积和衍射强度比(R)均落入上述范围内,并含有0.40-1.00meq / g酸性 总量为0.40至1.10meq / g的基团。 这些用于口服的吸附剂在体内几乎不吸附有用组分,并且具有吸附有毒物质的良好性能,即显示出有利的选择性吸附性能。
    • 2. 发明公开
    • PROCESS FOR PRODUCTION OF POLYARYLENE SULFIDE
    • VERFAHREN ZUR HERSTELLUNG VON POLYARYLENSULFID
    • EP1440996A4
    • 2005-08-17
    • EP02768108
    • 2002-09-27
    • KUREHA CHEMICAL IND CO LTD
    • KAGOSHIMA MASARUMATSUZAKI MITSUHIRO
    • C08G75/02
    • C08G75/0254C08G75/0204
    • There is provided a method for producing a poly (arylene sulfide) in which a dihalo-aromatic compound and an alkali metal halide are polymerized by heating in an organic amide solvent, wherein the cooling time for the polymerization reaction system is significantly reduced. After the polymerization process, there is provided a cooling process for cooling the polymerization reaction system comprising a liquid phase containing the product poly (arylene sulfide) and the organic amide solvent and a vapor phase containing a gas component (A); and in the cooling process, the gas component (A) in the vapor phase is cooled while the content of a low boiling gas component (A1) , which has a lower boiling point than water and exists in the gas component (A), is reduced in the vapor phase of the polymerization system.
    • 通过在有机酰胺溶剂中加热二卤代芳族化合物和碱金属硫化物以进行聚合来制备聚芳硫醚的方法,这使得聚合体系的冷却时间显着降低。 在聚合工序之后,进行用于冷却含有形成的聚芳撑硫醚和有机酰胺溶剂的液相和含有气体成分A的气相的聚合体系的冷却工序,在冷却工序中,将含有 汽相被冷却并且汽相中气态组分A中所含的低沸点气态组分A1的含量降低,并且沸点低于水的沸点。