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    • 5. 发明公开
    • APPARATUS AND METHOD FOR FORMULATING AND ASEPTICALLY FILLING LIQUID PRODUCTS
    • 设备和表达和液体产品无菌灌装方法
    • EP2207427A1
    • 2010-07-21
    • EP08834803.2
    • 2008-10-03
    • Medical Instill Technologies, Inc.
    • PY, Daniel
    • A23B5/005B65B55/00
    • A23L3/04A23L2/46A23L3/22B65B3/04B65B55/025B65B55/10B65B55/12
    • An apparatus and method are provided for formulating and aseptically filling liquid products. A first liquid source includes at least one first liquid component; a second liquid source includes at least one second liquid component; and a container includes a body defining an empty, sterile storage chamber therein that is sealed with respect to ambient atmosphere. The container is introduced into a sterile filling chamber. A first filling member coupled in fluid communication with the first liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the first liquid component is aseptically introduced through the first filling member and into the storage chamber. A second filling member coupled in fluid communication with the second liquid source is placed in fluid communication with the storage chamber of the container located in the sterile filling chamber, and the second liquid component is aseptically introduced through the second filling member and into the storage chamber and, in turn, the first and second liquid components are combined into a liquid product formulation within the sterile chamber of the container. The first and second filling members are withdrawn from fluid communication with the storage chamber of the container located within the sterile filling chamber, and the filled storage chamber is sealed with respect to ambient atmosphere to hermetically seal the liquid product formulation within the storage chamber of the container.