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1. 发明公开

EP3265785A1 METHODS AND SYSTEMS FOR PERFORMING TISSUE CLASSIFICATION USING MULTI-CHANNEL TR-LIFS AND MULTIVARIATE ANALYSIS 审中-公开
标题翻译：使用多通道TR-LIFS和多变量分析进行组织分类的方法和系统
公开(公告)号：EP3265785A1
公开(公告)日：2018-01-10
申请号：EP16860766.1
申请日：2016-10-27
申请人： Cedars-Sinai Medical Center
发明人： BLACK, Keith L. , BAKER, Michael , JONES, Howland , BUTTE, Pramod
IPC分类号： G01N21/64 , A61B5/00 , G01J3/02 , G01J3/28 , G01J3/44
CPC分类号： A61B5/0071 , A61B5/00 , A61B5/0075 , A61B5/0091 , A61B5/08 , A61B5/4064 , A61B5/4255 , A61B5/441 , A61B5/7267 , A61B10/02 , A61B2017/00057 , A61B2576/026 , G01N21/6402 , G01N21/6408 , G01N2201/06113 , G01N2201/129 , G06K9/6267 , G06T7/0012 , G06T2207/10064 , G06T2207/30016 , G06T2207/30028 , G06T2207/30061 , G06T2207/30068 , G06T2207/30088
摘要： Described herein are methods and systems for analyzing a sample by applying time resolved laser induced fluorescence spectroscopy to the sample to measure lifetime time decay profile data relating to the sample, and applying multivariate analysis to process the data so as to classify a sample as, for example, normal or abnormal. The sample may be cells, fluid or tissue from any organ. The sample may be in vitro or in vivo. The data may be obtained in situ or in vitro.

2. 发明公开

EP2437483A3 Image processing apparatus, image processing method, and image processing program 审中-公开
标题翻译：图像处理装置，图像处理方法和图像处理程序
公开(公告)号：EP2437483A3
公开(公告)日：2017-12-13
申请号：EP11007890.4
申请日：2011-09-28
申请人： Olympus Corporation
发明人： Kono, Takashi , Kanda, Yamato , Kitamura, Makoto , Matsuda, Takehiro , Hirota, Masashi
IPC分类号： H04N5/14 , G06T7/00
CPC分类号： H04N5/142 , G06T7/13 , G06T7/181 , G06T2207/10068 , G06T2207/30028 , G06T2207/30092
摘要： An image processing apparatus (1c) includes a contour-candidate-edge detecting unit (16; 16a) that detects, as contour candidate edges, edges on the basis of a gradient magnitude of each pixel in a target image; a contour-edge detecting unit (17) that detect contour edges by performing thresholding on gradient magnitudes of the contour candidate edges; an interpolation-line generating unit (18; 18c) that generates a plurality of interpolation lines for connecting end points of respective end-point pairs on the basis of gradients of pixel values between the end points of the respective end-point pairs while each of the end point pairs is made up of an end point of an identical contour edge as a connection base and an end point of a different contour edge as a connection destination; and a contour-edge interpolating unit (19c) that selects one of the interpolation lines on the basis of gradients of pixel values of pixels on the interpolation lines, and interpolates a contour edge between end points, which are to be connected with the selected interpolation line, with the selected interpolation line.
摘要翻译：图像处理装置（1c）包括：轮廓候选边缘检测单元（16; 16a），其基于目标图像中的每个像素的梯度大小来检测边缘作为轮廓候选边缘; 轮廓边缘检测单元（17），通过对轮廓候选边缘的梯度强度执行阈值处理来检测轮廓边缘; 插补线生成部（18,18c），其基于各端点对的端点间的像素值的梯度，生成用于连接各端点对的端点的多个插补线; 端点对由作为连接基础的相同轮廓边缘的端点和作为连接目的地的不同轮廓边缘的端点组成; 以及轮廓边缘内插单元（19c），其基于内插线上的像素的像素值的梯度来选择内插线中的一个，并且内插要与选择的内插相连接的端点之间的轮廓边缘线，与选定的插值线。

3. 发明公开

EP3207522A1 AUTOMATIC REGION-OF-INTEREST SEGMENTATION AND REGISTRATION OF DYNAMIC CONTRAST-ENHANCED IMAGES OF COLORECTAL TUMORS 审中-公开
标题翻译：动态增强对比度肿瘤图像的自动化区域分割和注册
公开(公告)号：EP3207522A1
公开(公告)日：2017-08-23
申请号：EP14904094.1
申请日：2014-10-13
申请人： Agency for Science, Technology and Research
发明人： HOU, Zujun , WANG, Yue
IPC分类号： G06T7/00 , G06K9/46 , G01R33/20
CPC分类号： G06T7/0012 , G01R33/5608 , G06K9/46 , G06T7/12 , G06T7/246 , G06T7/33 , G06T7/73 , G06T2207/10096 , G06T2207/20101 , G06T2207/30028 , G06T2207/30096
摘要： A method for dynamic contrast enhanced (DCE) image processing and kinetic modeling of an organ's region-of-interest is provided. The method includes deriving at least a contour of an exterior of the organ's region-of-interest from one or more of a plurality of images; generating a spline function in response to the derived contour of the exterior of the organ's region-of-interest from the one or more of the plurality of images; registering the plurality of images wherein the organ's region-of-interest has been segmented; deriving a tracer curve for the organ's region-of-interest in the registered images, the tracer curve indicating a change in concentration of a contrast agent flowing through the organ's region-of-interest over a time period; and kinetic modeling by fitting a kinetic model to the tracer curve to generate one or more maps of tissue physiological parameters associated with the kinetic model.
摘要翻译：提供了用于动态对比增强（DCE）图像处理和器官的感兴趣区域的动力学建模的方法。该方法包括从多个图像中的一个或多个中导出器官的感兴趣区域的外部的至少一个轮廓; 响应于来自所述多个图像中的所述一个或多个的所述器官的所述感兴趣区域的所述外部的所述导出轮廓，生成样条函数; 登记多个图像，其中器官的关注区域已被分割; 导出所登记的图像中的器官的感兴趣区域的示踪曲线，示踪曲线指示流过器官的感兴趣区域的造影剂在一段时间内的浓度变化; 以及通过将动力学模型拟合至示踪曲线以产生与动力学模型相关联的一个或多个组织生理参数图的动力学建模。

4. 发明公开

EP3085298A4 IMAGE-PROCESSING APPARATUS, IMAGE-PROCESSING METHOD, AND IMAGE-PROCESSING PROGRAM 审中-公开
标题翻译： BILDVERARBEITUNGSVORGHHTUNG，BILDVERARBEITUNGSVERFAHREN UND BILDVERARBEITUNGSPROGRAMM
公开(公告)号：EP3085298A4
公开(公告)日：2017-08-16
申请号：EP13899537
申请日：2013-12-19
申请人： OLYMPUS CORP
发明人： KONO TAKASHI , KANDA YAMATO , KITAMURA MAKOTO , KAMIYAMA TOSHIYA
IPC分类号： A61B1/04 , G06T1/00 , G06T7/00 , G06T7/11 , G06T7/64
CPC分类号： G06T7/11 , G06T7/0012 , G06T7/0081 , G06T7/64 , G06T2207/10068 , G06T2207/30028
摘要： Provided is an image processing apparatus, etc., that can accurately determine whether there are abnormal villi even if one image includes regions with different imaging distances to an object. An image processing apparatus 1 includes a region-of-interest setting unit 110 that sets a region of interest in an image; a linear convex region extracting unit 120 that extracts, from the region of interest, a linear region having a predetermined number or more of continuously-arranged pixels whose pixel values are higher than those of their neighboring pixels; an intra-region curvature feature data computing unit 130 that computes curvature feature data based on curvatures of one or more arcs along the linear region; and an abnormality determining unit 140 that determines whether there is an abnormal portion in the region of interest, based on a distribution of the curvature feature data.
摘要翻译：本发明提供一种图像处理装置等，即使一个图像包含与被摄体的成像距离不同的区域，也能够准确地判断是否存在异常绒毛。图像处理装置1包括：关注区域设定单元110，其设定图像中的关注区域; 线性凸起区域提取单元120，其从关注区域提取具有预定数量或更多的连续排列的像素的线性区域，该像素的像素值高于其相邻像素的像素值; 区域内曲率特征数据计算单元130，其基于沿线性区域的一个或多个弧的曲率来计算曲率特征数据; 以及基于曲率特征数据的分布来确定在关注区域中是否存在异常部分的异常确定单元140。

5. 发明授权

EP2030558B1 THREE-DIMENSIONAL IMAGE FORMING DEVICE, THREE-DIMENSIONAL IMAGE FORMING METHOD AND PROGRAM 有权
标题翻译： VORRICHTUNG ZUR FORMUNG EINES DREIDIMENSIONALEN BILDES，VERFAHREN ZUR FORMUNG EINES DREIDIMENSIONALEN BILDES UND PROGRAMM
公开(公告)号：EP2030558B1
公开(公告)日：2017-05-03
申请号：EP07744488
申请日：2007-05-31
申请人： NAT UNIV CORP CHIBA UNIV
发明人： IGARASHI TATSUO , ZENBUTSU SATOKI
IPC分类号： A61B1/04 , A61B1/00 , A61B5/107 , G02B23/26 , G06T1/00 , G06T7/00 , G06T15/00 , G06T17/00 , H04N7/18
CPC分类号： A61B1/042 , A61B5/1076 , G06T7/507 , G06T7/55 , G06T17/00 , G06T2207/10016 , G06T2207/10068 , G06T2207/30028

6. 发明公开

EP2172147A4 MEDICAL IMAGE PROCESSING DEVICE AND MEDICAL IMAGE PROCESSING METHOD 无效转让
标题翻译：药理学家BILDVERARBEITUNGSVORRICHTUNG MEDICINISCHES BILDVERARBEITUNGSVERFAHREN
公开(公告)号：EP2172147A4
公开(公告)日：2017-01-25
申请号：EP08740050
申请日：2008-04-08
申请人： OLYMPUS CORP
发明人： YOSHIDA RYOKO
IPC分类号： G06T7/00 , A61B1/00 , A61B1/04 , G06T7/60
CPC分类号： G06T7/0012 , A61B1/05 , G06T7/64 , G06T2207/10068 , G06T2207/30028 , G06T2207/30092

7. 发明公开

EP3109826A2 USING 3D VISION FOR AUTOMATED INDUSTRIAL INSPECTION 有权
标题翻译： VERWENDUNG VON 3D-SICHTFÜRAUTOMATISIERTE INDUSTRIELLE INSPEKTION
公开(公告)号：EP3109826A2
公开(公告)日：2016-12-28
申请号：EP16176181.2
申请日：2016-06-24
申请人： Cognex Corporation
发明人： MICHAEL, David J.
IPC分类号： G06T7/00
CPC分类号： G06T7/001 , G06T2207/10028 , G06T2207/30028
摘要： A system and method for three dimensional (3D) vision inspection using a 3D vision system. The system and method comprising acquiring at least one 3D image of a 3D object using the 3D vision system, using the 3D vision system; extracting a 3D visible runtime mask of the 3D image; using the 3D vision system, comparing the 3D runtime visible mask to a 3D reference visible mask; and, using the 3D vision system, determining if a difference of pixels exists between the 3D runtime visible mask and the 3D reference visible mask.
摘要翻译：使用3D视觉系统进行三维（3D）视觉检查的系统和方法。该系统和方法包括使用3D视觉系统使用3D视觉系统获取3D对象的至少一个3D图像; 提取3D图像的3D可视运行时间掩码; 使用3D视觉系统，将3D运行时可见蒙版与3D参考可见蒙版进行比较; 并且使用3D视觉系统，确定3D运行时间可见掩模和3D参考可见掩模之间是否存在像素差异。

8. 发明授权

EP2474949B1 Image processing device, image processing method, and image processing program 有权
标题翻译：图像处理装置，图像处理方法和图像处理程序
公开(公告)号：EP2474949B1
公开(公告)日：2016-11-30
申请号：EP11010280.3
申请日：2011-12-29
申请人： Olympus Corporation
发明人： Hirota, Masashi , Kanda, Yamato , Kitamura, Makoto , Kono, Takashi
IPC分类号： G06T7/00
CPC分类号： G06T7/12 , G06T7/11 , G06T2207/10068 , G06T2207/30028 , G06T2207/30092

9. 发明公开

EP3085298A1 IMAGE-PROCESSING APPARATUS, IMAGE-PROCESSING METHOD, AND IMAGE-PROCESSING PROGRAM 审中-公开
标题翻译：图像处理装置，图像处理方法和图像处理程序
公开(公告)号：EP3085298A1
公开(公告)日：2016-10-26
申请号：EP13899537.8
申请日：2013-12-19
申请人： Olympus Corporation
发明人： KONO, Takashi , KANDA, Yamato , KITAMURA, Makoto , KAMIYAMA, Toshiya
IPC分类号： A61B1/04 , G06T1/00
CPC分类号： G06T7/11 , G06T7/0012 , G06T7/64 , G06T2207/10068 , G06T2207/30028
摘要： Provided is an image processing apparatus, etc., that can accurately determine whether there are abnormal villi even if one image includes regions with different imaging distances to an object. An image processing apparatus 1 includes a region-of-interest setting unit 110 that sets a region of interest in an image; a linear convex region extracting unit 120 that extracts, from the region of interest, a linear region having a predetermined number or more of continuously-arranged pixels whose pixel values are higher than those of their neighboring pixels; an intra-region curvature feature data computing unit 130 that computes curvature feature data based on curvatures of one or more arcs along the linear region; and an abnormality determining unit 140 that determines whether there is an abnormal portion in the region of interest, based on a distribution of the curvature feature data.
摘要翻译：本发明提供一种图像处理装置等，即使一个图像包含与被摄体的成像距离不同的区域，也能够准确地判断是否存在异常绒毛。图像处理装置1包括：关注区域设定单元110，其设定图像中的关注区域; 线性凸起区域提取单元120，其从关注区域提取具有预定数量或更多的连续排列的像素的线性区域，该像素的像素值高于其相邻像素的像素值; 区域内曲率特征数据计算单元130，其基于沿线性区域的一个或多个弧的曲率来计算曲率特征数据; 以及基于曲率特征数据的分布来确定在关注区域中是否存在异常部分的异常确定单元140。

10. 发明公开

EP2875776A4 IMAGE PROCESSING DEVICE AND ENDOSCOPIC INSTRUMENT 有权转让
标题翻译：图像处理装置和内窥镜仪器
公开(公告)号：EP2875776A4
公开(公告)日：2016-10-19
申请号：EP13819790
申请日：2013-05-14
申请人： HOYA CORP
发明人： IKEMOTO YOUSUKE
IPC分类号： A61B1/04 , G06T5/00
CPC分类号： G06T7/0014 , A61B1/00009 , A61B5/061 , G06T5/007 , G06T7/0012 , G06T2207/10024 , G06T2207/10068 , G06T2207/20172 , G06T2207/30028 , G06T2207/30096
摘要： An image processing device, comprising an obtaining means that obtains color endoscopic image data, a color space conversion means that converts a color space of the color endoscopic image data to an HSI color space based on hue, saturation and intensity or an HSV color space based hue, saturation and a value, a lesion pixel judgment means that judges, for each of pixels constituting a color endoscopic image, whether or not each pixel is a lesion portion based on the hue and the saturation, an overlay processing means that executes an overlay process which changes a color of the pixel judged to be the lesion portion by the lesion pixel judgment means, and an overlay image display means that displays an overlay image obtained by subjecting the color endoscopic image to the overlay process.

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