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2. 发明公开

EP3389735A1 BIOLOGICALLY INERT COATING FOR IMPLANTABLE MEDICAL DEVICES 有权
公开(公告)号：EP3389735A1
公开(公告)日：2018-10-24
申请号：EP16826531.2
申请日：2016-12-18
申请人： Cardiac Pacemakers, Inc.
发明人： DELANEY, JR., Joseph T. , WULFMAN, David R. , GRUBA, Sarah M. , KANE, Michael J.
IPC分类号： A61L27/34
CPC分类号： A61L31/10 , A61L27/34 , A61L2420/02 , A61L2420/08 , A61L27/16 , C08L65/04 , A61L27/18 , C08L71/02
摘要： A coating for an implantable medical device includes a poly(monochloro-p-xylylene) coating formed on at least a portion of the implantable medical device, and a layer including at least one of poly(ethylene glycol) and a poly(ethylene glycol) derivative linked to the poly(monochloro-p-xylylene) coating by covalent bonds.

3. 发明公开

EP3058962A1 LUBRICIOUS COATING FOR MEDICAL DEVICE 审中-公开
标题翻译： SCHEMERENDE BESCHICHTUNGFÜRMEDISINISCHE VORRICHTUNG
公开(公告)号：EP3058962A1
公开(公告)日：2016-08-24
申请号：EP16162573.6
申请日：2002-01-24
申请人： Becton Dickinson and Company
发明人： Johnson, Steven, Wayne , Tingey, Kevin , Purdy, Robert, E , Orr, Douglas, P , Lee, Min-Shiu
IPC分类号： A61L29/08 , A61L29/14 , A61M25/06 , A61M39/04
CPC分类号： A61L29/085 , Y10T428/266 , Y10T428/3154 , C08L39/06 , C08L65/04 , C08L27/18
摘要： A lubrication system is disclosed which minimizes friction and that is useful for application on the surface of a flexible portion of a medical device. Such a lubrication system includes a lubricant that is able to move when the flexible portion of the medical device flexes and is biocompatible and is not degraded by the application of alcohol or other conventional medical sterilizing and cleaning agents. The lubrication is bonded to the surface of the flexible portion of the medical device. The lubrication system may be used on an elastomeric septum, such as a silicone rubber elastomer. The lubricant coating may be any type of coating that can be chemically bonded to the elastomer, such as di-paraxylene, poly-(p-xylene), polytetrafluoroethylene, or polyvinylpyrrolidone.
摘要翻译：公开了一种润滑系统，其最小化摩擦并且可用于在医疗装置的柔性部分的表面上的应用。这种润滑系统包括当医疗装置的柔性部分弯曲并且是生物相容性并且不会被酒精或其它常规医疗消毒和清洁剂的应用降解时能够移动的润滑剂。润滑结合到医疗装置的柔性部分的表面。润滑系统可用于弹性体隔膜，例如硅橡胶弹性体。润滑剂涂层可以是可以化学键合到弹性体的任何类型的涂层，例如二对二甲苯，聚（对二甲苯），聚四氟乙烯或聚乙烯吡咯烷酮。

4. 发明授权

EP1935355B1 Schlauch für die enterale Ernährung 有权
标题翻译：管肠内营养
公开(公告)号：EP1935355B1
公开(公告)日：2015-12-02
申请号：EP06025588.2
申请日：2006-12-11
申请人： N.V. Nutricia
发明人： Wolkenstörfer, Reinhold
IPC分类号： A61L29/06 , A61B17/00 , A61L29/08 , A61L29/16 , A61B17/34 , A61J15/00
CPC分类号： A61B17/3415 , A61B2017/00889 , A61B2017/00893 , A61J15/00 , A61J15/0026 , A61L29/06 , A61L29/085 , A61L29/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , C08L65/04

5. 发明公开

EP2290028A2 Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition 审中-公开
标题翻译：水性压敏胶粘剂组合物，其生产方法和使用该组合物的压敏胶粘带
公开(公告)号：EP2290028A2
公开(公告)日：2011-03-02
申请号：EP10013023.6
申请日：2002-12-02
申请人： PERMACEL , Nitto Denko Corporation
发明人： Contrada, Svetlana, I. , Nakamura, Koichi , Hamblin, David R., Jr.
IPC分类号： C09J7/04 , C09J7/02 , C09J133/08
CPC分类号： C09J133/14 , C08G2170/40 , C08L33/04 , C08L33/26 , C08L65/04 , C08L2666/04 , C09J7/385 , C09J133/10 , C09J2201/606 , C09J2400/283 , Y10T428/28 , Y10T428/2891
摘要： A pressure-sensitive adhesive composition comprising a water-soluble polymer A, a water-insoluble component B, a water-incompatible solvent C that dissolves the water-insoluble component B and is incompatible with water, a water-soluble plasticizer D, and water, wherein the pressure-sensitive adhesive composition in a dry state has water solubility according to Technical Association of The Pulp and Paper Industry Useful Method 213 (TAPPI UM 213). Also disclosed are a method for producing a pressure-sensitive adhesive composition according to the present invention, comprising the steps of: preliminarily preparing a true nonaqueous solution of a water-insoluble component B in a water-incompatible solvent C, and mixing the true nonaqueous solution with an aqueous solution of at least one member selected from the group consisting of a water-soluble polymer A and a water-soluble plasticizer D, and a pressure-sensitive adhesive and a pressure-sensitive adhesive tape that use the composition.
摘要翻译：一种压敏粘合剂组合物，其包含水溶性聚合物A，水不溶性组分B，溶解水不溶性组分B且与水不相容的水不溶性溶剂C，水溶性增塑剂D和水其中，根据纸浆和造纸工业有用方法技术协会213（TAPPI UM 213），处于干燥状态的压敏粘合剂组合物具有水溶性。还公开了制备本发明压敏粘合剂组合物的方法，该方法包括以下步骤：预先制备非水溶性组分B的真正非水溶液在水不相容性溶剂C中，并将真正的非水溶液溶液与选自由水溶性聚合物A和水溶性增塑剂D组成的组中的至少一种成分的水溶液以及使用该组合物的压敏粘合剂和压敏粘合带。

6. 发明公开

EP2147688A2 Endoprothese und Verfahren zur Herstellung derselben 有权
标题翻译：内置假体及其制造方法
公开(公告)号：EP2147688A2
公开(公告)日：2010-01-27
申请号：EP09163889.0
申请日：2009-06-26
申请人： Biotronik VI Patent AG
发明人： Klocke, Björn
IPC分类号： A61L31/02 , A61L31/10 , A61L31/14
CPC分类号： A61L31/022 , A61F2250/0036 , A61L31/10 , A61L31/148 , A61L31/16 , C08L65/04
摘要： Es wird eine Endoprothese, insbesondere intraluminale Endoprothese, z. B. ein Stent, mit einem Grundgitter bestehend aus einem zumindest weitestgehend biodegradierbaren Material und einer auf dem biodegradierbaren Material angeordneten Beschichtung (30) vorgeschlagen. Zur besseren Steuerung der Degradation ist das Grundgitter im Wesentlichen vollständig durch eine Beschichtung (30) bedeckt, die Parylene, vorzugsweise mindestens überwiegend Parylene, besonders bevorzugt Parylene C oder Parylene N, enthält, wobei die Dicke der Beschichtung (30) zwischen etwa 0,1 µm und etwa 10 µm, bevorzugt zwischen etwa 0,4 µm und etwa 7 µm, besonders bevorzugt zwischen etwa 1 µm und etwa 5 µm beträgt. Es wird ferner ein Verfahren zur Herstellung einer derartigen Endoprothese vorgeschlagen.
摘要翻译：它是内假体，特别是内假体腔内，例如，作为支架，具有由至少基本可生物降解的材料制成的提议的基本晶格和，布置在所述可生物降解的材料涂层（30）。为更好地控制降解的，基网格基本上完全由涂层（30）覆盖的被覆盖，该聚对二甲苯，优选至少主要聚对二甲苯，更优选帕利灵C或聚对二甲苯N，含有与所述涂层（30）的厚度为约0.1之间微米和大约10微米之间，优选在约0.4微米至约7微米，更优选介于约1微米到约5微米。进一步提出制造这种内假体的方法。

7. 发明授权

EP1372493B1 BIOACTIVE OCCLUSION COIL 有权
标题翻译：生物活性闭塞
公开(公告)号：EP1372493B1
公开(公告)日：2008-12-17
申请号：EP02726690.7
申请日：2002-04-03
申请人： Boston Scientific Limited
发明人： HO, Hanh , QUAN, Kenneth, W., Jr. , TEOH, Clifford , ABRAMS, Robert, M. , EDER, Joseph, C. , SLAIKEU, Paul, C. , WALLACE, Micheal P. , BARRY, James
IPC分类号： A61B17/12
CPC分类号： A61L31/044 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12172 , A61B17/12177 , A61B2017/12063 , A61F2/0077 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/412 , A61L2430/36 , C08L67/04 , C08L65/04
摘要： One aspect of the present invention pertains to an implantable medical device (205) for at least partially obstructing a neck portion (120) of a vascular aneurysm (100). The device includes an occlusion subassembly (202) comprising a base section (210) and at least one lateral protrusion (205) fixedly attached to the base section (210). A therapeutic agent (600) is disposed upon at least one portion of at least one lateral protrusion (205).

8. 发明公开

EP1862506A1 ANTISTATIC COMPOSITION 有权
标题翻译：抗生素ZUSAMMENSETZUNG
公开(公告)号：EP1862506A1
公开(公告)日：2007-12-05
申请号：EP06715464.1
申请日：2006-03-09
申请人： Adeka Corporation
发明人： ABE, Tetsuji , SHIRAI, Hiroaki , TSUDA, Takayuki
IPC分类号： C08L61/14 , C08K5/00 , C09K3/16 , C08L69/00 , C08L101/00
CPC分类号： C08K5/41 , C08K5/0075 , C08K5/09 , C08K5/42 , C08K5/523 , C08L61/14 , C08L65/04 , C08L69/00 , C08L2201/04 , C09K3/16 , Y10S524/91 , C08L2666/16
摘要： The present invention provides an antistatic composition including: a polymer (A) containing a monomer unit represented by the following general formula (1):

where R 1 represents a hydrocarbon group having a benzene ring, A represents a methyl group or an ethyl group, and a plurality of A's may be the same or different from each other, m and n, each of which is an average polymerization degree of an oxyalkylene group, each represent a numeral of 1 or more, and p represents a numeral of 2 or more; and a low-molecular-weight anionic compound (B).
摘要翻译：本发明提供一种抗静电组合物，其包含：含有由以下通式（1）表示的单体单元的聚合物（A）：其中R 1表示具有苯环的烃基，A表示甲基或乙基，并且多个A可以彼此相同或不同，m和n各自为氧化烯基的平均聚合度，各自表示1以上的数，p表示2以上的数 ; 和低分子量阴离子化合物（B）。

9. 发明公开

EP1804880A1 MEDICAL DEVICES AND METHODS OF PREPARATION AND USE 审中-公开
标题翻译：医疗设备和制造方法及其应用
公开(公告)号：EP1804880A1
公开(公告)日：2007-07-11
申请号：EP05801018.2
申请日：2005-09-14
申请人： Specialty Coating Systems, Inc.
发明人： GREINER, Andreas , HANEFELD, Phillip , KUMAR, Rakesh
IPC分类号： A61M25/00 , A61L29/04 , A61K47/32 , A61K6/083 , A61F2/00 , B05D3/00
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/606 , A61L2420/02 , C08L65/04
摘要： An implantable device having a coating with an eluting membrane and a permeable membrane disposed on a surface of the device is provided. The eluting membrane is typically a polymeric material capable of being infused with a biologically active, therapeutic substance. The permeable membrane is typically a polymeric material having a thickness that controls the rate of transport of the biologically active material to a target tissue. The polymeric materials are typically parylene or derivatives thereof.

10. 发明公开

EP1588722A1 HEMOSTATIC MATERIALS 审中-公开
标题翻译： ÄMOSTATISCHEMATERIALIEN
公开(公告)号：EP1588722A1
公开(公告)日：2005-10-26
申请号：EP04702784.2
申请日：2004-01-16
申请人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
发明人： UCHIDA, Takanori , SHINYA, Noriko , KAETSU, Hiroshi
IPC分类号： A61L15/00 , A61F13/00
CPC分类号： A61L15/32 , A61F13/36 , A61F2013/00472 , A61L15/26 , A61L2400/04 , Y10T442/2508 , Y10T442/2525 , Y10T442/2861 , Y10T442/696 , C08L65/04
摘要： A safe and effective hemostatic material is provided. A hemostatic material comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material. The use of the hemostatic material of the present invention allows for quick and thorough hemostasis for both projectile bleeding and exudative bleeding.
摘要翻译：提供安全有效的止血材料。一种止血材料，其包含作为有效成分的凝血酶和纤维蛋白原，其特征在于使用生物可吸收的合成非织造织物作为支持材料。使用本发明的止血材料可以快速和彻底地止血用于射弹出血和渗出性出血。

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