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1. 发明授权

EP2725017B1 CHROMENE COMPOUND 有权
标题翻译： CHROME LINK
公开(公告)号：EP2725017B1
公开(公告)日：2016-06-29
申请号：EP12803316.4
申请日：2012-06-19
申请人： Tokuyama Corporation
发明人： IZUMI, Shinobu , TERANISHI, Kazuhiro , DAIKOKU, Yusuke , SANDO, Mitsuyoshi
IPC分类号： C07D311/78 , C07C39/17 , C07C43/23 , C07C323/21 , C07D295/08 , C07D327/06 , C07D407/04 , C07D497/10 , C09K9/02 , G02B5/23 , C07C39/23 , C08L83/04
CPC分类号： C09K9/02 , C07C39/17 , C07C39/23 , C07C43/23 , C07C323/21 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2603/94 , C07D295/096 , C07D311/92 , C07D327/04 , C07D497/10 , C08L83/04 , C09K2211/1007 , C09K2211/1011 , C09K2211/1088 , G02B5/23 , Y10T428/31504

2. 发明公开

EP2516385A2 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES 审中-公开
标题翻译： 2-（BICYCLISCHE ARYLOXY）CARBOXAMIDE ALS FUNGIZIDE
公开(公告)号：EP2516385A2
公开(公告)日：2012-10-31
申请号：EP10798443.7
申请日：2010-12-22
申请人： E. I. du Pont de Nemours and Company
发明人： CREWS JR, Alvin, Donald , DING, Amy, X. , TSENG, Chi-Ping
IPC分类号： C07C235/08 , A01N37/34 , A01N39/04 , C07C255/53 , C07C215/20
CPC分类号： C07D217/24 , A01N39/04 , A01N43/42 , A01N55/00 , C07C235/08 , C07C255/29 , C07C271/20 , C07C323/21 , C07C327/30 , C07C327/42 , C07C2601/02 , C07C2601/14 , C07D215/20 , C07F9/3211 , C07F9/60 , C07F9/62
摘要： Disclosed are compounds of Formula 1,
N- oxides, and salts thereof (Formula 1) wherein Q is O or S; Z
1 and Z
2 are each independently CR
9 or N; and R
1 , R
2 ,R
3 ,R
4 ,R
5 ,R
6 ,R
7 ,R
8 and R
9 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
摘要翻译：公开了式1，N-氧化物及其盐的化合物，其中Q是O或S; Z1和Z2各自独立地为CR9或N; 并且R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9如本公开所定义。还公开了含有式1化合物和控制由真菌病原体引起的植物病害的方法的组合物，其包括施用有效量的本发明化合物或组合物。

3. 发明公开

EP1620086A1 COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS OF PREPARATION 审中-公开
标题翻译：维多利亚州自由民主主义人民共和国
公开(公告)号：EP1620086A1
公开(公告)日：2006-02-01
申请号：EP04725756.3
申请日：2004-04-05
申请人： Warner-Lambert Company LLC
发明人： BRATTON, Larry Don, Pfizer Global R & D , CHENG, Xue-Min, Pfizer Global R & D , ERASGA, Noe Ouane, Pfizer Global R & D , FILZEN, Gary Frederick, Pfizer Global R & D , GEYER, Andrew George, Pfizer Global R & D , LEE, Chitase, Pfizer Global R & D , TRIVEDI, Bharat Kalidas, Pfizer Global R & D , UNANGST, Paul Charles, Pfizer Global R & D
IPC分类号： A61K31/381 , C07D333/60 , C07C323/21 , A61K31/192 , A61P9/10 , A61P3/00 , C07D413/12 , C07D405/12 , A61K31/352 , C07D311/58 , C07C62/10 , C07D417/12 , C07D213/34 , C07C323/20 , C07D307/79
CPC分类号： C07D213/74 , C07C59/72 , C07C62/34 , C07C323/20 , C07C323/21 , C07C323/22 , C07C323/25 , C07C323/62 , C07C2601/02 , C07C2602/08 , C07C2602/10 , C07C2603/18 , C07D213/34 , C07D215/36 , C07D261/08 , C07D263/57 , C07D263/58 , C07D307/79 , C07D311/58 , C07D333/22 , C07D333/60 , C07D405/12 , C07D413/12 , C07D417/12
摘要： This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing dyslipidemia, hypercholesterolemia, obesity, hyperglycemia, atherosclerosis, hypertriglyceridemia and hyperinsulinemia in a mammal. The present invention also relates to methods for making the disclosed compounds.
摘要翻译：本发明涉及改变PPAR活性的化合物。本发明还涉及化合物的药学上可接受的盐，包含该化合物或其盐的药学上可接受的组合物，以及使用它们作为治疗或预防哺乳动物血脂异常，高胆固醇血症，肥胖症，高血糖症，动脉粥样硬化，高甘油三酯血症和高胰岛素血症的治疗剂的方法。本发明还涉及制备所公开的化合物的方法。

4. 发明公开

EP1191020A3 Material for organic electroluminescence device and use thereof 失效
标题翻译：材料为有机电致发光装置及其使用
公开(公告)号：EP1191020A3
公开(公告)日：2003-01-15
申请号：EP01126365.4
申请日：1997-12-09
申请人： TOYO INK MANUFACTURING CO., LTD.
发明人： Enokida, Toshio, Toyo Ink Manufacturing Co., Ltd. , Onikubo, Toshikazu, Toyo Ink Manufact. Co., Ltd. , Okutsu, Satoshi, Toyo Ink Manufacturing Co., Ltd. , Tamano, Michiko, Toyo Ink Manufacturing Co., Ltd.
IPC分类号： C07C321/22 , C07C43/20 , C07C43/257 , C07C211/49 , C07C211/54 , H05B33/14 , H01L51/20
CPC分类号： C07D213/643 , C07C43/20 , C07C43/235 , C07C43/257 , C07C211/61 , C07C217/92 , C07C321/28 , C07C321/30 , C07C323/12 , C07C323/21 , C07C2601/14 , C07C2602/10 , C07C2603/24 , C07C2603/42 , C07C2603/50 , C07D209/88 , C07D213/70 , C07D271/113 , C07D295/135 , C07D307/58 , C07D319/14 , C07D333/32 , C07D333/34 , C07D487/14 , C07D493/04 , C07D493/14 , C07D495/14 , C07D513/14 , C09K11/06 , H01L51/006 , H01L51/5048 , H05B33/14 , Y10S428/917 , Y10T428/26
摘要： A compound suitable for use in an electroluminescence device, having hole-injecting capability and durability and having the formula [I], [II] or [III] wherein R 1 to R 17 are organic residues, X 1 to X 18 are heteroatoms and A 1 and A 2 are chemically rational organic residues composed of C, H and O atoms or of C, H, O and S atoms, having molecular weight of 500 or less.

5. 发明公开

EP1191020A2 Material for organic electroluminescence device and use thereof 失效
标题翻译：材料eel organische Elektrolumineszenzvorrichtung和seine Verwendung
公开(公告)号：EP1191020A2
公开(公告)日：2002-03-27
申请号：EP01126365.4
申请日：1997-12-09
申请人： TOYO INK MANUFACTURING CO., LTD.
发明人： Enokida, Toshio, Toyo Ink Manufacturing Co., Ltd. , Onikubo, Toshikazu, Toyo Ink Manufact. Co., Ltd. , Okutsu, Satoshi, Toyo Ink Manufacturing Co., Ltd. , Tamano, Michiko, Toyo Ink Manufacturing Co., Ltd.
IPC分类号： C07C321/22 , C07C43/20 , C07C43/257 , C07C211/49 , C07C211/54 , H05B33/14 , H01L51/20
CPC分类号： C07D213/643 , C07C43/20 , C07C43/235 , C07C43/257 , C07C211/61 , C07C217/92 , C07C321/28 , C07C321/30 , C07C323/12 , C07C323/21 , C07C2601/14 , C07C2602/10 , C07C2603/24 , C07C2603/42 , C07C2603/50 , C07D209/88 , C07D213/70 , C07D271/113 , C07D295/135 , C07D307/58 , C07D319/14 , C07D333/32 , C07D333/34 , C07D487/14 , C07D493/04 , C07D493/14 , C07D495/14 , C07D513/14 , C09K11/06 , H01L51/006 , H01L51/5048 , H05B33/14 , Y10S428/917 , Y10T428/26
摘要： A compound suitable for use in an electroluminescence device, having hole-injecting capability and durability and having the formula [I], [II] or [III]
wherein R 1 to R 17 are organic residues, X 1 to X 18 are heteroatoms and A 1 and A 2 are chemically rational organic residues composed of C, H and O atoms or of C, H, O and S atoms, having molecular weight of 500 or less.
摘要翻译：适合用于具有空穴注入能力和耐久性的具有空穴注入能力和耐久性的具有下式的化合物的化合物：其中R 1至R 17均为有机残基，X 1至X 17， 18>是杂原子，A 1和A 2是由C，H和O原子或分子量为500以下的C，H，O和S原子组成的化学合理的有机残基。

6. 发明公开

EP0839807A1 Synthesis of benzo(f)quinolinones 失效
标题翻译：苯并（F）chinolinone-SYNTHESE
公开(公告)号：EP0839807A1
公开(公告)日：1998-05-06
申请号：EP97308644.0
申请日：1997-10-29
申请人： ELI LILLY AND COMPANY
发明人： Brennan, John , Doecke, Christopher William , Heath, Perry Clark , Patterson, Lawrence Edward , Udodong, Uko Effiong , Weigel, Leland Otto
IPC分类号： C07D221/10 , C07C323/22
CPC分类号： C07D417/12 , C07C319/14 , C07C319/20 , C07C323/22 , C07C2602/10 , C07D221/10 , C07C323/21 , C07C323/38 , C07C323/62
摘要： A process for preparing intermediates and benzoquinolin-3-one pharmaceuticals, of the following formula I:
wherein R 1 represents:
2-nitrophenyl, 4-nitrophenyl, 2-cyanophenyl, 4-cyanophenyl, 2-nitronaphthyl, 4-nitronaphthyl, 2-cyanonaphthyl, 4-cyanonaphthyl, 2-quinolinyl, 4-quinolinyl, 7-quinolinyl, 1-isoquinolinyl, 3-isoquinolinyl, 8-isoquinolinyl, 2-quinoxalinyl, 2-benzothiazolyl, 3-1H-indazolyl, 2-benzoxazolyl, 3-1,2-benzisothiazolyl, 2-pyridinyl, 4-pyridinyl, 2-pyrazinyl, 2-naphtho[2,3-d]thiazolyl, 2-naphto[1,2-d]thiazolyl, 9-anthryl, 2-thiazolyl, 2-benzimidazolyl, 1-benz[g]isoquinolinyl, 8-benz[g]isoquinolinyl, 5-1H-tetrazolyl, 2-quinazolinyl, 2-thiazolo[4,5-b]pyridinyl, 4-10H-pyridazino[3,2-b]-2-quinazolinyl, 2-1,4-benzodioxinyl, 2-triazine, 2-benzoxazine, 4-benzoxazine, 2-purine or 8-purine.
Such pharmaceuticals are effective in treating conditions consequent on 5α-reductase.
摘要翻译：制备下式I的中间体和苯并喹啉-3-酮药物的方法：其中R 1表示：2-硝基苯基，4-硝基苯基，2-氰基苯基，4-氰基苯基，2-硝基萘基，4 2-硝基萘基，2-氰基萘基，4-氰基萘基，2-喹啉基，4-喹啉基，7-喹啉基，1-异喹啉基，3-异喹啉基，8-异喹啉基，2-喹喔啉基，2-苯并噻唑基，3-1H-吲唑基， - 苯并恶唑基，3-1,2-苯并异噻唑基，2-吡啶基，4-吡啶基，2-吡嗪基，2-萘并[2,3]恶噻唑基，2-萘并[1,2]噻唑基，9-蒽基，2-噻唑基，2-苯并咪唑基，1-苯并异喹啉基，8-苯并异喹啉基，5-1H-四唑基，2-喹唑啉基，2-噻唑并[4,5-b]吡啶基，4-10H-哒嗪基-3,3,2-b] -2-喹唑啉基，2-1,4-苯并二恶英基，2 3-三嗪，2-苯并恶嗪，4-苯并恶嗪，2-嘌呤或8-嘌呤。这样的药物在治疗5α-还原酶的病症方面是有效的。

7. 发明授权

EP0419676B1 THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME 失效
标题翻译： THIONAPHTHALEN衍生物，方法生产及其抗过敏剂。
公开(公告)号：EP0419676B1
公开(公告)日：1994-12-07
申请号：EP90905649.1
申请日：1990-03-30
申请人： TEIJIN LIMITED
发明人： HAZATO, Atsuo , KATO, Yoshinori , KUROZUMI, Seizi , OHMORI, Hitoshi , MINOSHIMA, Toru , OSADA, Yoshio , NAGATA, Ikuo , KOMORIYA, Keiji
IPC分类号： C07C317/22 , C07C317/44 , C07C323/21 , C07C323/22 , C07C323/52 , C07C323/56 , C07C323/60 , C07D207/333 , C07D213/32 , C07D213/50
CPC分类号： C07D207/333 , C07C317/22 , C07C317/44 , C07C323/21 , C07C323/22 , C07C323/52 , C07C323/60 , C07D213/32 , C07D213/50 , C07D241/12 , C07D257/04 , C07D277/26 , C07D333/22
摘要： Thionaphthalene derivatives represented by formula (I) and nontoxic salts thereof, wherein R represents hydrogen, (un)substituted C1 to C5 alkyl, (un)substituted aryl, heterocyclic group, R4CO- (wherein R4 represents (un)substituted C¿1? to C5 alkyl, (un)substituted aryl, or heterocyclic group), R?5¿OCO- (wherein R5 represents hydrogen, (un)substituted C¿1? to C10 alkyl, (un)substituted C3 to C10 alkenyl, or (un)substituted C5 to C7 cycloalkyl), R?6¿NHCO- (wherein R6 represents (un)substituted C¿1? to C5 alkyl, (un)substituted aryl, or heterocyclic group), or cyano; R?1 and R2¿ represent each independently hydrogen, C¿1? to C5 alkyl, or phenyl; R?3¿ represents hydrogen, C¿1? to C5 alkyl, or R?7¿CO- (wherein R7 represents -OR?81, -R82¿, or -NR¿2??83, and R81, R82 and R83¿ represent each C¿1? to C4 alkyl); and n represents an integer of 0 to 2.

8. 发明授权

EP0344112B1 Substituierte Bisacyloxynaphtacene und Verfahren zur Herstellung von Tetrathiotetracenen 失效
标题翻译：取代的二异氰酸酯和制备四氯乙烯的方法
公开(公告)号：EP0344112B1
公开(公告)日：1993-01-20
申请号：EP89810366.8
申请日：1989-05-18
申请人： CIBA-GEIGY AG
发明人： Baumann, Marcus, Dr. , Mayer, Carl, W., Dr. , Wernet, Wolfgang, Dr. , Fischer, Walter, Dr.
IPC分类号： C07C69/017 , C07C69/18 , C07C317/22 , C07C323/21 , C07F7/08 , C07D495/06
CPC分类号： C07D495/06 , B05D1/202 , B82Y30/00 , B82Y40/00 , C07C69/00 , C07C317/22 , C07C323/21 , C07C2603/00 , C07C2603/44 , C07F7/0818 , C08G61/123 , H01B1/121

9. 发明公开

EP2669278A4 CHROMENE COMPOUND 有权
公开(公告)号：EP2669278A4
公开(公告)日：2014-06-25
申请号：EP12739535
申请日：2012-01-25
申请人： TOKUYAMA CORP
发明人： TAKAHASHI TOSHIAKI , TAKENAKA JUNJI , MOMODA JUNJI , TERANISHI KAZUHIRO , IZUMI SHINOBU
IPC分类号： C07D311/78 , C07C323/21 , C07C323/38 , C09K9/02 , G02B5/23 , G02C7/10
CPC分类号： G02B1/041 , C07C215/74 , C07C321/28 , C07C323/21 , C07C323/38 , C07C2603/94 , C07D295/096 , C07D307/42 , C07D311/60 , C07D311/78 , C07D333/18 , C07D407/04 , C07D409/04 , C08L2666/70 , C09K9/02 , C09K2211/1007 , C09K2211/1033 , C09K2211/1088 , C09K2211/1092 , G02B1/04 , G02B5/23 , G02C7/102 , Y10T428/31533

10. 发明公开

EP2669277A4 CHROMENE COMPOUND 有权
公开(公告)号：EP2669277A4
公开(公告)日：2014-06-25
申请号：EP12739310
申请日：2012-01-26
申请人： TOKUYAMA CORP
发明人： TAKAHASHI TOSHIAKI , TAKENAKA JUNJI , MOMODA JUNJI , TERANISHI KAZUHIRO , SANDO MITSUYOSHI , IZUMI SHINOBU
IPC分类号： C07D311/78 , C07C323/21 , C09K9/02 , G02B5/23 , G02C7/10
CPC分类号： G02B1/041 , C07C323/21 , C07C2603/94 , C07D311/78 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1088 , C09K2211/1092 , G02B5/23 , G02C7/102

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