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1. 发明公开

EP3271075A1 DISPOSITIF DE PREPARATION D'UNE COUCHE DE CELLULES BIOLOGIQUES SUR UNE LAME ET APPAREIL DE PREPARATION AUTOMATIQUE D'UNE COUCHE DE CELLULES UTILISANT LEDIT DISPOSITIF 有权
标题翻译：用于在刀片上制备一层生物细胞的装置和使用所述装置自动制备一层细胞的装置
公开(公告)号：EP3271075A1
公开(公告)日：2018-01-24
申请号：EP16721856.9
申请日：2016-03-18
申请人： R.A.L. Diagnostics
发明人： LE COMTE, Roger, Lucien, Marie
IPC分类号： B01L3/02 , B01L3/00 , G01N1/28
CPC分类号： G01N1/2813 , B01L3/0272 , B01L3/50825 , B01L3/5088 , B01L3/5635 , B01L2300/0672 , B01L2300/0822 , G01N1/286 , G01N35/00029 , G01N35/1081 , G01N2015/0065
摘要： The subject matter of the invention is a device for preparing a layer of biological cells (10) on a deposition surface (4) of a slide (1), said device comprising a body provided with a channel (14), said body comprising a first end (18) forming an inlet tip (12) intended to enter inside a container (2) containing a biological liquid (5), closed by a cap (6) and a second end (17) forming a depositing tip (15) intended to deposit a drop of said liquid on the deposition surface (4), said second end (17) comprising a spreading means (20) comprising a blade (22) arranged in a plane (28) forming an angle of inclination α with the plane (24) of the deposition surface (4) and elastic return means (21) interposed between said blade and said second end.

2. 发明授权

EP2573005B1 Tropfenspender 有权
标题翻译：滴管
公开(公告)号：EP2573005B1
公开(公告)日：2017-11-01
申请号：EP12183511.0
申请日：2012-09-07
申请人： Aptar Radolfzell GmbH
发明人： Wochele, Matthias
IPC分类号： B65D47/18 , B65D47/20 , A61F9/00 , B01L3/00
CPC分类号： B65D47/18 , A61F9/0008 , B01L3/00 , B01L3/0272 , B01L2300/161 , B65D47/2068

3. 发明授权

EP2193846B1 Container for providing reagents 有权转让
标题翻译：容器提供试剂
公开(公告)号：EP2193846B1
公开(公告)日：2016-09-21
申请号：EP09180494.8
申请日：2006-08-01
申请人： Life Technologies Corporation
发明人： Unger, Alex , Topfer, Mike , Busch, Nicole , Hynek, Tom , Aidehag, Fredrik , Pelman, Todd , Naley, Martin
IPC分类号： B01L3/00 , B65D1/02 , G09F3/00
CPC分类号： B01L3/5457 , B01L3/0272 , B01L3/523 , B01L3/545 , B01L2200/16 , B01L2300/021 , B01L2300/022 , B01L2300/028 , B01L2300/042 , B01L2300/043 , B01L2300/047 , B01L2300/0851 , B01L2300/0858 , B65D1/0223 , B65D2203/02 , B67D7/00 , C12M99/00 , G01N2035/00673 , G01N2035/00792 , G01N2035/0436 , G06Q10/087 , G06Q30/0621 , G06Q30/0633 , G06Q30/0641 , G09F3/00 , G09F23/00

4. 发明公开

EP2913401A3 Lyophilizate of substance-binding solid-phase carrier, vessel for binding substance in substance-containing liquid to substance-binding solid-phase carrier, and method of producing lyophilizate containing substance-binding solid-phase carrier 审中-公开
标题翻译：在含有物质的液体，以冻干物的固相载体接合和制造过程中的结合物质与一种物质结合固相支持stoffbindendem固相支持容器的冷冻干燥物
公开(公告)号：EP2913401A3
公开(公告)日：2015-09-09
申请号：EP15156290.7
申请日：2015-02-24
申请人： Seiko Epson Corporation
发明人： Koeda, Hiroshi , Idegami, Kotaro
IPC分类号： C12N15/10 , B01L3/00 , G01N35/00
CPC分类号： C12Q1/6806 , B01L3/0272 , B01L3/5635 , B01L2200/0668 , B01L2300/042 , B01L2300/0681 , B01L2400/043 , B01L2400/0481 , C12N15/1013
摘要： A lyophilizate containing a substance-binding solid-phase carrier, which is obtained by lyophilizing the substance-binding solid-phase carrier together with an additive, a vessel for binding a substance in a substance-containing liquid to a substance-binding solid-phase carrier, in which a lyophilizate obtained by lyophilizing the substance-binding solid-phase carrier together with an additive is provided, and a method of producing a lyophilizate containing a substance-binding solid-phase carrier, which includes lyophilizing the substance-binding solid-phase carrier together with an additive, are provided.

5. 发明公开

EP2344216A1 DEVICE FOR TRANSFER OF BODY FLUIDS 有权
标题翻译：设备用于转移体液中
公开(公告)号：EP2344216A1
公开(公告)日：2011-07-20
申请号：EP09815479.2
申请日：2009-09-23
申请人： Noble House Group Pty. Ltd.
发明人： BURKE, Craig, Andrew
IPC分类号： A61M1/00 , A61M5/14 , A61M25/00
CPC分类号： B01L3/0255 , A61M5/162 , B01L3/0272 , B01L3/5635 , B01L2200/085 , B01L2200/087 , B01L2300/0854 , B01L2400/0457
摘要： A cannula (10) for use in removing samples of fluid from a container sealed with a pierceable membrane, the cannula including a hollow needle like portion (12) having a pointed forward end (20) shaped to allow forcible penetration through the membrane, the rear end (14) having a first bore (26) and an insert (40) located within the first bore (40) that reduces the effective size of the first bore (26) without blocking the first bore (26).

6. 发明授权

EP0981729B1 Multi-chamber dispenser comprising a deformable housing 失效
标题翻译：多腔室的分配器具有可变形壳体
公开(公告)号：EP0981729B1
公开(公告)日：2007-04-04
申请号：EP98906591.7
申请日：1998-02-19
申请人： NASON, Frederic L.
发明人： Nason, Frederic L.
IPC分类号： G01N1/02 , B01L3/02 , B65D25/08
CPC分类号： B01L3/0272 , B01L2400/0481 , B65D81/3211 , Y10T436/25 , Y10T436/2575
摘要： A reagent dispenser (10) is provided for dispensing multiple reagents particularly for use in analyzing biological specimens and the like. The dispenser (10) includes a pair of reagent chambers (46, 50) with selected reagents (44, 48) therein, and a dual nib (34) for hermetically sealing the reagent chambers (46, 50). A portion (22) of the dispenser is deformable to break or otherwise to displace the nib (34) in a manner permitting the two reagents (44, 48) to flow together and mix within one of the reagent chambers (46, 50). The deformable portion (22) or the dispenser (10) can then be squeezed to express the mixed reagents for delivery to contact a speciment to be analyzed. In a preferred form, the dispenser (10) comprises a cap assembly (21, 43) for removable mounting onto an open-ended tubular housing (14) to cooperatively define a specimen chamber (16) within the housing (14) for receiving the specimen on a swab (54) or the like.

7. 发明公开

EP0558479A4 EP0558479A4 - 失效
标题翻译： EP0558479A4 - Google专利
公开(公告)号：EP0558479A4
公开(公告)日：1994-01-05
申请号：EP91903999
申请日：1990-11-30
申请人： PALL CORPORATION , MERCK & CO. INC.
发明人： MATKOVICH, VLADO, I. , SCHLAUCHDECKER, THOMAS, E. , HENLEY, MARTIN, W. , BORMANN, THOMAS
IPC分类号： A61J1/10 , A61F9/00 , A61J1/00 , A61J1/05 , A61J1/14 , A61M3/00 , A61M35/00 , B01L3/00 , B01L3/02 , B65D47/18 , B67D7/76 , B67D5/58
CPC分类号： B01L3/0272 , A61F9/0008 , A61J1/145 , A61J1/1456 , B65D47/18
摘要： This invention relates to the field of liquid dispensing and metering devices that dispense a solution in drop form and protects the solution from contamination. In applications where contamination and proper dosage is a concern, the prior art discloses dispensers related both to the use of anti-bacterial agents added to the solution to prevent contamination and the use of a single dose device. Both present problems, as the addition of the agent causes allergic reactions in some users, while the single dose device is inconvenient to the frequent user. Prior art dispensers also do not permit control of metering for proper dosage. This invention solves these problems by providing a filter in the dropper portion of the device to prevent contamination of the solution. The device includes a dropper (2) having an outlet (3) and filter (4). The filter is a composite consisting of a liquophilic component (5) and a liquophobic component (6).
摘要翻译：液体分配和计量装置技术领域本发明涉及液体分配和计量装置的领域，其分配液滴形式的溶液并保护溶液免受污染。在涉及污染物和合适剂量的应用中，现有技术公开了与使用添加到溶液中的抗菌剂以防止污染以及使用单剂量装置有关的分配器。目前存在的两个问题，因为添加药物导致一些使用者出现过敏反应，而单剂量装置对频繁使用者不方便。现有技术的分配器也不允许控制适当剂量的计量。本发明通过在装置的滴管部分提供过滤器来解决这些问题，以防止溶液污染。该装置包括具有出口（3）和过滤器（4）的滴管（2）。过滤器是由嗜液组分（5）和疏液组分（6）组成的复合物。

8. 发明公开

EP0398739A2 Filter applicator 失效
标题翻译： Applikatorröhrchenmit einem过滤器。
公开(公告)号：EP0398739A2
公开(公告)日：1990-11-22
申请号：EP90305383.3
申请日：1990-05-18
申请人： QUIDEL CORPORATION
发明人： Rosman, Daniel B. , Rundle, Douglas D. , Ascani, Gary A. , Mortensen, Richard B. , Tom, Henry
IPC分类号： G01N33/543 , G01N33/53 , B01L3/02 , B01L3/14
CPC分类号： B01L3/0272 , B01L2400/0481 , G01N33/5302 , G01N33/54366 , G01N2035/1055
摘要： A sample applicator for use in performing immunoassays comprises a tube defining an internal lumen and having a filter matrix at one end thereof. Sample is drawn into the applicator tube, either using a vacuum bulb or an automated assay device. The sample is filtered as it enters the tube, and is again filtered as it discharged from the tube in the opposite flow direction. By removing particulates from the liquid sample, assay performance can be greatly improved. The applicator may also comprise a reagent dispersed within a permeable matrix, which is useful for introducing reagent to a sample or other liquid assay component. As a liquid assay component is drawn into the applicator tube, the reagent is reconstituted by and mixed with the liquid, thereby reducing the number of steps required for the assay.
摘要翻译：用于进行免疫测定的样品施加器包括限定内腔并在其一端具有过滤器基质的管。使用真空灯泡或自动测定装置将样品吸入涂敷管。样品在进入管时被过滤，并且在从管中以相反的流动方向排出时再次过滤。通过从液体样品中除去颗粒物，可以大大提高测定性能。施用器还可以包含分散在可渗透基质内的试剂，其可用于将试剂引入样品或其它液体测定组分。当液体测定组分被吸入施用管中时，试剂由液体重构并与其混合，从而减少测定所需的步骤数。

9. 发明公开

EP0269345A2 Method of moulding a micropipette 失效
标题翻译： Verfahren zum Formen einer Feinpipette。
公开(公告)号：EP0269345A2
公开(公告)日：1988-06-01
申请号：EP87310114.1
申请日：1987-11-16
申请人： Mochida Pharmaceutical Co., Ltd.
发明人： Masahiro, Baba
IPC分类号： B29C45/16 , B29C45/26 , B01L3/02
CPC分类号： B01L3/0272 , B01L2400/0481 , B29C45/16 , B29C45/261
摘要： Instead of being moulded by injection of the measured amount of polymer from a single rearward entrance port, which leads to mould wear and flashing of polymer at the delivery end at 15, micropipettes are moulded using an intermediate cavity entrance 14, a first measured body of molten polymer being injected through said entrance and caused or allowed to move forward towards the front end at 15 to at least start to cool and resolidify, and a second measured body of molten polymer being immediately injected through the same entrance 14 and caused or allowed to move rearwardly, and at least start to cool and resolidify, and weld together the two bodies of polymer.
摘要翻译：代替通过从单个后进入口注入测量量的聚合物来模制，这导致聚合物在输送端15处的模具磨损和闪烁，使用中间腔入口14来模制微量吸管，第一测量体熔融聚合物通过所述入口注入并在15处被引导或允许向前端向前移动，至少开始冷却和重新固化，并且第二测量的熔融聚合物体立即通过相同的入口14注入并引起或允许向后移动，并至少开始冷却和重新固化，并将两个聚合物体结合在一起。

10. 发明公开

EP4350351A3 BIOLOGICAL FLUID MICRO-SAMPLE MANAGEMENT DEVICE 审中-公开
公开(公告)号：EP4350351A3
公开(公告)日：2024-06-26
申请号：EP24159367.2
申请日：2016-03-09
申请人： Becton, Dickinson and Company
发明人： Ivosevic, Milan , Bokka Srinivasa Rao, Kishore K. , Skutnik, Peter , Torris, Anthony V.
IPC分类号： B01L3/00 , B01L3/02 , B01L3/14 , A61B5/15 , A61B5/154
CPC分类号： B01L3/0296 , A61B5/154 , B01L3/0272 , B01L2300/02120130101 , B01L2300/04820130101 , B01L2300/060920130101 , B01L2300/083820130101 , B01L2300/08720130101 , B01L2400/048120130101 , B01L2400/04920130101 , A61B5/15003 , A61B5/150755 , B01L3/502 , B01L2200/060520130101 , B01L2300/083220130101 , G01N33/49
摘要： A biological fluid collection device includes a collection module and an outer housing. The collection module includes a housing comprising a first end having a sample introduction opening, a second end having a sample dispensing opening, and a passageway extending between the sample introduction opening and the sample dispensing opening. A mixing chamber and a holding chamber are in fluid communication with the passageway such that a sample introduced into the sample introduction opening passes through the mixing chamber and subsequently into the holding chamber. The biological fluid collection device further includes a closure covering the first end, a cap covering the second end and including a vented plug, and an activation member adapted to force a sample contained in the holding chamber out of the sample dispensing opening. The collection module is positioned inside of the outer housing and the closure closes the open end of the outer housing.

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