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    • 7. 发明公开
    • HOLLOW FIBER MEMBRANE FOR USE IN AN ANESTHETIC CIRCUIT
    • 空心纤维膜用于麻醉电路
    • EP3235558A1
    • 2017-10-25
    • EP16166434.7
    • 2016-04-21
    • 3M Innovative Properties CompanyDMF Medical Incorporated
    • The designation of the inventor has not yet been filed
    • B01D69/08B01D53/22B01D71/26
    • B01D69/08B01D53/22B01D53/228B01D69/087B01D71/26B01D2053/224B01D2256/10B01D2257/504B01D2259/4533B01D2325/022B01D2325/20Y02C10/10
    • Hydrophobic poly(4-methyl-1-pentene) hollow fiber membrane for retention of anesthetic agents with an inner and an outer surface and between inner and outer surface an essentially isotropic support layer with a sponge-like, open-pored, microporous structure free of macrovoids and adjacent to this support layer on the outer surface a dense separation layer with a thickness between 1.0 and 3.5 µm. The membrane has a porosity in the range of greater than 35% to less than 50% by volume and a permeance for CO 2 of 20-60 mol/(h·m 2 ·bar), a gas separation factor α(CO 2 /N 2 ) of at least 5 and a selectivity CO 2 / anesthetic agents of at least 150.
      The process for producing this membrane is based on a thermally induced phase separation process in which process a homogeneous solution of a poly(4-methyl-1-pentene) in a solvent system containing compounds A and B is formed, wherein compound A is a strong solvent and compound B a weak non-solvent for the polymer component. After formation of a hollow fiber the hollow fiber is cooled in a liquid cooling medium to form a hollow fiber membrane. The concentration of the polymer component in the solution may be between 42.5- and 45.8 wt.-% and the hollow fiber leaving the die runs through a gap between die and cooling medium with a gap length in the range of 5-30 mm.
    • 疏水性聚(4-甲基-1-戊烯)中空纤维膜,用于保持具有内表面和外表面以及内外表面之间的麻醉剂,基本上是各向同性的支持层,其具有类似海绵状的开孔微孔结构 的大孔并且在该外表面上与该支撑层相邻处具有厚度在1.0和3.5μm之间的致密隔离层。 膜的孔隙率在35体积%以上且小于50体积%的范围内,CO 2的渗透性为20〜60摩尔/(h·m 2·巴),气体分离系数α(CO 2 / N 2)为 至少为5,选择性CO 2 /麻醉剂的选择性至少为150.生产该膜的方法基于热诱导相分离过程,在该过程中,聚(4-甲基-1-戊烯)在 形成含有化合物A和B的溶剂体系,其中化合物A是强溶剂,化合物B是聚合物组分弱的非溶剂。 在形成中空纤维之后,中空纤维在液体冷却介质中冷却以形成中空纤维膜。 溶液中聚合物组分的浓度可以在42.5重量%和45.8重量%之间,离开模头的中空纤维通过模头和冷却介质之间的间隙,间隙长度在5-30mm范围内。