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1. 发明授权

EP3381507B1 MULTI-ELECTRODE STIMULATION THERAPY WITH REDUCED ENERGY 有权
公开(公告)号：EP3381507B1
公开(公告)日：2024-08-14
申请号：EP18161378.7
申请日：2018-03-13
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/0551 , A61N1/36142 , A61N1/36164 , A61N1/36171 , A61N1/36062

2. 发明公开

EP3242712A4 PATIENT REMOTE AND ASSOCIATED METHODS OF USE WITH A NERVE STIMULATION SYSTEM 有权转让
公开(公告)号：EP3242712A4
公开(公告)日：2018-07-25
申请号：EP16735557
申请日：2016-01-11
申请人： AXONICS MODULATION TECH INC
发明人： SCHROEDER DENNIS , SCHMID ERIC , JIANG GUANGQIANG , WOOCK JOHN
IPC分类号： A61N1/08 , A61N1/05 , A61N1/36
CPC分类号： A61N1/37247 , A61N1/36057 , A61N1/36128 , A61N1/36132 , A61N1/36142 , A61N1/36146 , A61N1/37211 , A61N1/37235 , A61N1/37241
摘要： A neurostimulation system having an external or an implantable pulse generator programmed to innervate a specific nerve or group of nerves in a patient through an electrode as a mode of treatment, having a patient remote that wirelessly communicates with the pulse generator to increase stimulation, decrease stimulation, and provide indications to a patient regarding the status of the neurostimulation system. The patient remote can allow for adjustment of stimulation power within a clinically effective range and for turning on and turning off the pulse generator. The patient remote and neurostimulation system can also store a stimulation level when the pulse generator is turned off and automatically restore the pulse generator to the stored stimulation level when the pulse generator is turned on.

3. 发明授权

EP3113834B1 THERAPEUTIC WINDOW DETERMINATION 有权
标题翻译：治疗窗口的确定
公开(公告)号：EP3113834B1
公开(公告)日：2018-04-04
申请号：EP14816056.7
申请日：2014-12-03
申请人： Medtronic, Inc.
发明人： KAEMMERER, William F.
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/36139 , A61N1/36142 , A61N1/37247
摘要： A therapeutic window for at least one electrode of a medical system may be determined based on a volume of tissue expected to be activated (“VTA”) by electrical stimulation delivered by the at least one electrode. In some examples, a processor determines the therapeutic window for a particular electrode by at least determining an efficacy threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the efficacy threshold, and determining an adverse-effects threshold based on the VTA expected to result from the delivery of electrical stimulation according to a set of electrical stimulation parameter values including the stimulation parameter at the adverse-effects threshold.

4. 发明公开

EP3287090A1 IMPLANT MODE FOR ELECTROSURGICAL GENERATOR 有权
标题翻译：电动发电机的植入模式
公开(公告)号：EP3287090A1
公开(公告)日：2018-02-28
申请号：EP17187177.5
申请日：2017-08-22
申请人： Covidien LP
发明人： DUNNING, James E. , ANDERSON, Sara E. , BUYSSE, Steven P.
IPC分类号： A61B18/12 , A61B18/14 , A61N1/36 , A61N1/37 , A61N1/39 , A61B5/00
CPC分类号： A61B18/1233 , A61B5/0031 , A61B5/686 , A61B18/1445 , A61B18/1477 , A61B18/1482 , A61B2018/00577 , A61B2018/00601 , A61B2018/00636 , A61B2018/00642 , A61B2018/00702 , A61B2018/0072 , A61B2018/00726 , A61B2018/00732 , A61B2018/00767 , A61B2018/00988 , A61B2018/1293 , A61N1/36142 , A61N1/3718 , A61N1/3931
摘要： Disclosed are devices, systems, and methods for operating an electrosurgical generator, including a radio-frequency (RF) output stage configured to output an electrosurgical waveform, a wireless transceiver configured to communicate with an implantable device in a patient, and a controller coupled to the RF output stage and the wireless transceiver, the controller configured to control the RF output stage to generate an electrosurgical waveform based on the implantable device.
摘要翻译：公开了用于操作电外科发生器的设备，系统和方法，所述电外科发生器包括被配置为输出电外科波形的射频（RF）输出级，被配置为与患者中的可植入设备通信的无线收发器，所述RF输出级和所述无线收发器，所述控制器被配置为控制所述RF输出级以基于所述可植入装置生成电外科波形。

5. 发明授权

EP3102284B1 IMPLANTABLE MEDICAL DEVICES, AND SYSTEMS TO CONTINUE IMPLEMENTING A SPECIAL MODE OF OPERATION AFTER EXPERIENCING A DEVICE RESET 有权
公开(公告)号：EP3102284B1
公开(公告)日：2018-01-10
申请号：EP15702344
申请日：2015-01-21
申请人： MEDTRONIC INC
发明人： JENISON TROY A , LEVY MICHAEL D , RHODES BENJAMIN P , STANCER CHRISTOPHER C
IPC分类号： A61N1/37 , A61N1/08 , A61N1/36 , A61N1/39
CPC分类号： A61N1/3718 , A61M5/14276 , A61M2205/50 , A61M2210/0693 , A61M2210/1003 , A61N1/08 , A61N1/36142 , A61N1/37235 , A61N1/3925
摘要： An implantable medical device implements a special mode of operation, such as a mode of electrical stimulation therapy, during conditions where there may be an increased likelihood that a device reset will occur. The implantable medical device recovers from the device reset by copying values that specify the special mode and that are stored in a non-volatile memory to an operating memory. The special mode is implemented after the device reset has occurred by using the values copied to the operating memory. One version of the special mode is an MRI mode that allows the implantable medical device to safely operate during an MRI scan. The fields of the MRI scan may trigger a device reset, but the MRI mode values are copied from the non-volatile memory to the operating memory, and the MRI mode is implemented after the reset by using the values copied to the operating memory.

6. 发明授权

EP2015833B1 APPARATUS TO PROVIDE IMPEDANCE SAFETY CHECKS FOR NEURAL STIMULATION 有权
标题翻译： VORRICHTUNG ZUR BEREITSTELLUNG VONIMPEDANZSICHERHEITSPRÜFUNGENFÜRNERVENSTIMULATION
公开(公告)号：EP2015833B1
公开(公告)日：2017-06-07
申请号：EP07776437
申请日：2007-04-27
申请人： SECOND SIGHT MEDICAL PRODUCTS INC
发明人： GREENBERG ROBERT JAY , MCCLURE KELLY HOBART , LITTLE JAMES SINGLETON , DAI RONGQING , ROY ARUP , CASTRO RICHARD AGUSTIN , REINHOLD JOHN , TANG KEA-TIONG , YADAV SUMIT , ZHOU CHUNHONG , ZHOU DAO MIN , MAKSY PISHOY
IPC分类号： A61N1/05 , A61N1/08 , A61N1/36
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/0551 , A61N1/08 , A61N1/36142 , A61N1/36185
摘要： The present invention provides a neural stimulator. The neural stimulator comprises a plurality of electrodes suitable to stimulate neural tissue. A maximum charge is predetermined. The neural stimulator also comprises a device for input of data for neural stimulation and a calculating device for calculating stimulation. The calculation of stimulation levels is based upon the data and the predetermined maximum charge. Levels are reduced if the data indicates stimulation levels exceeding the predetermined maximum charge, and produces reduced stimulation levels. The neural stimulator also comprises a current pulse generator for stimulating said neural tissue according to the reduced stimulation level.
摘要翻译：本发明提供了一种神经刺激器。神经刺激器包括适于刺激神经组织的多个电极。最大费用是预先确定的。神经刺激器还包括用于输入用于神经刺激的数据的装置和用于计算刺激的计算装置。刺激水平的计算基于数据和预定的最大电荷。如果数据指示刺激水平超过预定的最大充电量并且产生降低的刺激水平，则水平降低。神经刺激器还包括电流脉冲发生器，用于根据降低的刺激水平来刺激所述神经组织。

7. 发明授权

EP2374502B1 Apparatus to provide safety checks for neural stimulation 有权
标题翻译：提供神经刺激安全检查的仪器
公开(公告)号：EP2374502B1
公开(公告)日：2016-08-24
申请号：EP11172764.0
申请日：2007-04-27
申请人： Second Sight Medical Products, Inc.
发明人： Greenberg, Robert , McClure, Kelly , Little, James , Dai, Rongqing , Roy, Arup , Castro, Richard , Reinhold, John , Tang, Kea-Tiong , Yadav, Sumit , Zhou, Chunhong , Zhou, Dao , Maksy, Pishoy
IPC分类号： A61N1/05 , A61N1/08 , A61N1/36
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/0551 , A61N1/08 , A61N1/36142 , A61N1/36185
摘要： The present invention provides a neural stimulator. The neural stimulator comprises a plurality of electrodes suitable to stimulate neural tissue. A maximum charge is predetermined. The neural stimulator also comprises a device for input of data for neural stimulation and a calculating device for calculating stimulation. The calculation of stimulation levels is based upon the data and the predetermined maximum charge. Levels are reduced if the data indicates stimulation levels exceeding the predetermined maximum charge, and produces reduced stimulation levels. The neural stimulator also comprises a current pulse generator for stimulating said neural tissue according to the reduced stimulation level.

8. 发明公开

EP3025757A1 MRT-TAUGLICHES AKTIVES IMPLANTIERBARES GERÄT UND MRT-SENSOR 有权
标题翻译： MRT-TAUGLICHES AKTIVES IMPLANTIBBESGERÄT
公开(公告)号：EP3025757A1
公开(公告)日：2016-06-01
申请号：EP15190504.9
申请日：2015-10-20
申请人： BIOTRONIK SE & Co. KG
发明人： Dörr, Thomas
IPC分类号： A61N1/37 , A61N1/08 , A61N1/39
CPC分类号： A61N1/08 , A61N1/36142 , A61N1/3718 , A61N1/3925 , A61N1/3931
摘要： Die Erfindung betrifft ein implantierbares elektronisches Gerät, das mindestens eine elektromagnetische Felderkennungseinheit aufweist, die mit wenigstens einer Antenne verbunden ist. Außerdem ist die Felderkennungseinheit ausgebildet, auf elektromagnetische Felder anzusprechen, die typischerweise in der Umgebung eines Patienten außerhalb der Umgebung eines MRT-Gerätes auftreten und in der Umgebung eines MRT-Gerätes abgeschirmt sind. Darüberhinaus ist die Felderkennungseinheit ausgebildet, die Abwesenheit solcher elektromagnetischer Felder anzuzeigen, die typischerweise in der Umgebung eines Patienten außerhalb der Umgebung eines MRT-Gerätes auftreten und in der Umgebung eines MRT-Gerätes abgeschirmt sind.
摘要翻译：实施例包括具有至少一个电磁场检测单元和至少一个天线的可植入电子设备，其中所述至少一个电磁场检测单元连接到所述至少一个天线。所述至少一个电磁场检测单元响应在MRI装置的环境外围的患者环境中出现或存在的电磁场，以及在MRI装置的环境中屏蔽的电磁场。所述至少一个电磁场检测单元指示不存在通常在MRI装置外部的患者周围的环境中发生并且在MRI装置的环境中被屏蔽的电磁场。

9. 发明公开

EP2961477A1 ELECTRICAL CHARGE BALANCING METHOD FOR FUNCTIONAL STIMULATION USING PRECISION PULSE WIDTH COMPENSATION 审中-公开
标题翻译：方法克服的电荷;功能性刺激用一个精确的脉冲宽度补偿
公开(公告)号：EP2961477A1
公开(公告)日：2016-01-06
申请号：EP14756729.1
申请日：2014-02-25
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： LIU, Wentai , HILL, Richard , LO, Yi-Kai , CHEN, Kuanfu
IPC分类号： A61N1/36 , A61N1/378 , A61N1/08
CPC分类号： A61N1/36157 , A61N1/36046 , A61N1/36125 , A61N1/36142 , A61N1/36146 , A61N1/3615
摘要： An apparatus and method for electrical charge balancing when generating a stimulus during functional neural stimulation is presented. A stimulus pulse is generated (cathodic or anodic), and after a selected delay a charge compensating pulse is generated of an opposite polarity. The electrode circuit discontinuously examines electrode voltage after termination of the stimulus pulse, and utilizes this voltage to determine how long to extend the width of the charge compensating pulse. The electrode circuit thus performs accurate electrical charge cancellation to remove residual charges from the electrode by precisely controlling pulse width for an opposing polarity compensating pulse that need not have the same current level as the stimulus pulse.
摘要翻译：为电荷平衡当生成功能神经刺激期间刺激的装置和方法。刺激脉冲产生（阴极或阳极），和一个相反极性的被产生的电荷补偿脉冲的选定延迟之后。电极电路断续检查电极电压刺激脉冲终止之后，并利用该电压来确定矿多久延长电荷补偿脉冲的宽度。电极电路因此执行准确的电荷消除从电极通过精确控制脉冲宽度在相反极性补偿脉冲并不需要具有相同的电流电平作为刺激脉冲除去残留的电荷。

10. 发明公开

EP2825252A1 NEUROSTIMULATION SYSTEM FOR PREVENTING MAGNETICALLY INDUCED CURRENTS IN ELECTRONIC CIRCUITRY 有权
标题翻译： NEURO刺激系统，防止磁感应电流的电子电路
公开(公告)号：EP2825252A1
公开(公告)日：2015-01-21
申请号：EP13713290.8
申请日：2013-03-13
申请人： Boston Scientific Neuromodulation Corporation
发明人： GURURAJ, Kiran , WEERAKOON, Pujitha , MARNFELDT, Goran N. , PARRAMON, Jordi , MURTONEN, Salomo , FELDMAN, Emanuel
IPC分类号： A61N1/08
CPC分类号： A61N1/36142 , A61N1/08 , A61N1/086 , A61N1/36 , A61N1/3605
摘要： A neurostimulation device capable of being placed between an active stimulation state and an inactive stimulation state and method of using same. The neurostimulation device comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of stimulation electrodes, a first solid-state switching device coupled to a first one of the electrical terminals, a variable power source coupled to the first switching device, and a controller configured for, when the neurostimulation device is in the inactive stimulation state, prompting the variable power source to selectively output a relatively low voltage to place the first switching device into a first open state and a relatively high voltage to place the first switching device into a second open state.

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