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1. 发明公开

EP3351280A1 MULTIPLE INJECTION NEEDLE ASSEMBLY 审中-公开
公开(公告)号：EP3351280A1
公开(公告)日：2018-07-25
申请号：EP17152798.9
申请日：2017-01-24
申请人： Terumo Europe NV
发明人： CASTELEYN, Pieter , DANIELS, Ludo , ROYEN, Veerle , FRIPON, Christian
IPC分类号： A61M5/32
CPC分类号： A61M5/32 , A61M5/329 , A61M5/3291 , A61M5/3295
摘要： Injection needle assembly comprising:
• at least N injection needles where N is at least four and a multiple of two,
• a first liquid port adapted to be connected to an injection device,
• N second liquid ports, each connected to one of the N injection needles,
• N 2 main liquid pathways each having an entrance connected to the first liquid port and an exit,
wherein it further comprises N 2 secondary liquid pathways comprising:
• two extremities each opening on one of the N second liquid ports, and
• a mid portion connected to the exit of one of the main liquid pathways;
and wherein the main liquid pathways and the secondary liquid pathways define N liquid flow paths between the first liquid port and the N second liquid ports and are dimensioned so that a pressure drop between the first liquid port and each of the N second liquid ports is similar.

2. 发明公开

EP2683429A2 RETRACTABLE SYRINGE WITH LOCKING PLUNGER 审中-公开
标题翻译：与制动活塞回缩式注射器
公开(公告)号：EP2683429A2
公开(公告)日：2014-01-15
申请号：EP12754794.1
申请日：2012-03-06
申请人： Midland Medical Devices Holdings, LLC
发明人： CAIZZA, Richard , BOJAN, Jay
IPC分类号： A61M5/34 , A61M5/315 , A61M5/50
CPC分类号： A61M5/3234 , A61M5/1782 , A61M5/3295 , A61M5/346 , A61M5/347 , A61M2005/3239
摘要： A retractable needle syringe having a plunger rod configured to lock in place after retraction of the needle. The plunger rod distal end has a seal configured to advance past a retaining ledge after retraction of the needle, whereby the retaining ledge restricts or inhibits the plunger from proximal movement.

3. 发明公开

EP2653184A1 Multi-needle injection system 有权
标题翻译： Intektionssystem mit mehreren Nadeln
公开(公告)号：EP2653184A1
公开(公告)日：2013-10-23
申请号：EP13164738.0
申请日：2013-04-22
申请人： Cook Medical Technologies LLC
发明人： Rodenberg, Jennifer , Bourdeau, William , Baxter, Charles , Charlebois, Steven , Wagner, Zach , Sherman, Sara
IPC分类号： A61M25/00
CPC分类号： A61M5/3295 , A61M25/0084 , A61M25/0097 , A61M2025/0008 , A61M2025/0086 , A61M2025/0087
摘要： A medical device (10) for treating stress urinary incontinence is provided. The device includes a cannula (20) with a plurality of apertures (34a, 34b, 34c). A plurality of needles (41, 42, 43) is disposed within a lumen (26) of the cannula. A handle (50) includes a housing (52) and a shifter mechanism (60) to translate the plurality of needles from a first position in which the needles are disposed within the lumen of the cannula, to a second position in which a distal portion of each needle extends out of the lumen through respective apertures. The handle also includes a slot (55) including a transversal track (55d) defining a potential range of rotational motion of the shifter mechanism with respect to the housing, and a plurality of longitudinal tracks (55a, 55b, 55c) defining a potential range of translational motion of the shifter mechanism with respect to the housing.
摘要翻译：提供了一种用于治疗压力性尿失禁的医疗装置（10）。该装置包括具有多个孔（34a，34b，34c）的套管（20）。多个针（41,42,43）设置在套管的内腔（26）内。手柄（50）包括壳体（52）和移位机构（60），用于将多个针从布置在套管内腔中的第一位置平移到第二位置，在第二位置，远端部分每个针通过相应的孔延伸出管腔。手柄还包括一个狭槽（55），它包括横向轨道（55d），该横向轨迹限定换挡机构相对于壳体的旋转运动的潜在范围，以及多个纵向轨迹（55a，55b，55c）移位机构相对于壳体的平移运动。

4. 发明公开

EP1625870A2 Needle for intradermal delivery of substances having penetration limiting means 无效
标题翻译： Intramerdalen针用于与装置输送的物质用于限制的穿透深度
公开(公告)号：EP1625870A2
公开(公告)日：2006-02-15
申请号：EP05021412.1
申请日：2001-06-29
申请人： Becton, Dickinson and Company
发明人： Pettis, Ronald J. , Down, James A. , Harvey, Noel G.
IPC分类号： A61M37/00 , A61M5/158 , A61M5/46
CPC分类号： A61M5/46 , A61K38/28 , A61K38/29 , A61M5/158 , A61M5/32 , A61M5/3286 , A61M5/3291 , A61M5/3295 , A61M37/0015 , A61M2037/0038 , A61M2037/0061
摘要： The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage.
摘要翻译：本发明提供了用于ID递送药物和其他物质对人或动物的改进方法。该方法采用小规格针，爱尤其微针，在皮内空间放置到作为推注或通过输注递送所述物质到皮内空间。已经发现没有皮肤与针出口的暴露高度内针出口的位置是通过小规格针有效递送的活性物质，以防止该物质的泄漏出皮肤并内提高吸收临界皮内空间。雅丁输送到本发明的方法激素类药物的药代动力学已被发现是非常类似于传统的SC递送的药代动力学，这表明没有ID管理雅丁到本发明的方法很可能产生类似的临床结果（即，相似的疗效）与减少或消除疼痛对于患者的优点。哪个地方的针出口处的皮内空间的适当的深度和控制音量和流体输送的速率递送装置提供准确输送的物质的到所需的位置，而不泄漏。

5. 发明公开

EP3148619A1 DOSE SETTING MECHANISM FOR DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 无效
标题翻译：新西兰帝国主义革命者伊朗伊斯兰革命运动ARZNEIMITTELABGABEVORRICHTUNG UND ARZNEIMITTELABGABEVORRICHTUNG
公开(公告)号：EP3148619A1
公开(公告)日：2017-04-05
申请号：EP15725600.9
申请日：2015-05-27
申请人： Sanofi-Aventis Deutschland GmbH
发明人： JONES, Matthew , STEEL, Samuel , BLUNDRED, Neal Alexander , BUTLER, Joseph , VEASEY, Robert , PLUMPTRE, David Aubrey
IPC分类号： A61M5/24 , A61M5/19 , A61M5/178 , A61M5/31 , A61M5/315
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2448 , A61M5/3146 , A61M5/31528 , A61M5/31538 , A61M5/31551 , A61M5/31575 , A61M5/31591 , A61M5/31593 , A61M5/3295 , A61M2005/1787 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.
摘要翻译：本发明涉及用于药物递送装置（1）的剂量设定机构，其包括主要药物递送组件（3）和辅助药物递送组件（4），其中所述剂量设定机构包括主剂量拨打部件（21）用于设定初级药物输送组件（3）中的剂量和用于设定次级药物递送组件（4）中的剂量的次级剂量拨打组件（29），其中主剂量拨号组件（21）和次级剂量拨号组件（29）被配置为在剂量设定期间旋转。为了有效的联合治疗治疗，齿轮机构（7）构造成使得在剂量设定的第一阶段中，主剂量拨盘部件（21）的旋转被传递到次级剂量拨号部件（29），并且使得在剂量设定的第二阶段，次级剂量拨号组件（29）与主剂量拨号组件（21）分离，从而防止主剂量拨号组件（21）的转动被传送到次级剂量拨号组件（29）。本发明还涉及各自的药物递送装置。

6. 发明公开

EP3127578A1 PUNCTURE INJECTION INSTRUMENT 有权
标题翻译： PUNKTIONSINJEKTIONSVORRICHTUNG
公开(公告)号：EP3127578A1
公开(公告)日：2017-02-08
申请号：EP15774122.4
申请日：2015-03-31
申请人： Toppan Printing Co., Ltd.
发明人： KODAMA, Yoshihiro , SUMIDA, Tomoya
IPC分类号： A61M37/00
CPC分类号： A61M5/3295 , A61B5/0066 , A61B5/441 , A61B8/0858 , A61B8/4444 , A61B8/4477 , A61B8/461 , A61M5/3158 , A61M5/31581 , A61M5/46 , A61M37/0015 , A61M2005/31588
摘要： A puncture injection instrument includes: a hollow needle body (10) having one or more projections (12) on a first surface of a substrate (11), each of the projections (12) being formed a through hole (13) penetrating from a distal end side of the projection (12) to a second surface of the substrate (11) opposite to the first surface; and an ultrasound probe (22). In the instrument, the ultrasound probe (22) is arranged outside a region in which the one or more projections (12) are formed.
摘要翻译：一种穿刺注射器具包括：在基底（11）的第一表面上具有一个或多个突起（12）的中空针体（10），每个突起（12）形成有从所述突起（12）的前端侧到与所述第一表面相对的所述基板（11）的第二表面; 和超声波探头（22）。在仪器中，超声波探头（22）布置在形成有一个或多个突起（12）的区域的外侧。

7. 发明授权

EP2683430B1 RETRACTABLE SYRINGE WITH SEGMENTED RETAINING LEDGE 失效
标题翻译：具有分段的支持STEG回缩式注射器
公开(公告)号：EP2683430B1
公开(公告)日：2016-12-14
申请号：EP12755069.7
申请日：2012-03-06
申请人： Midland Medical Devices Holdings, LLC
发明人： CAIZZA, Richard
IPC分类号： A61M5/34 , A61M5/50
CPC分类号： A61M5/3234 , A61M5/1782 , A61M5/3295 , A61M5/346 , A61M5/347 , A61M2005/3239

8. 发明公开

EP3035858A1 FLUID DELIVERY DEVICE 审中-公开
标题翻译：流体输送装置
公开(公告)号：EP3035858A1
公开(公告)日：2016-06-29
申请号：EP13824666.5
申请日：2013-12-16
申请人： Secretary, Department Of Biotechnology
发明人： BAGWAN, Siraj , PILLAI, Jonathan , SHARMA, Hanish , GARG, Pramod , MAKHARIA, Govind
IPC分类号： A61B17/00 , A61B17/12 , A61M5/178 , A61B10/02
CPC分类号： A61B10/0233 , A61B17/00491 , A61B17/0057 , A61B2017/00495 , A61B2017/00632 , A61B2017/0065 , A61B2017/00654 , A61B2217/007 , A61M5/3295
摘要： According to an embodiment, the present subject matter describes a device for delivery of one or more fluids in to a target site. The fluid delivery device (100) includes a housing (105, 205), a shaft (110), which may be disposed inside the housing (105, 205) to form at least one fluid chamber (115, 210) therebetween. Further, the fluid chamber (115, 210) is adapted to receive the one or more fluids. The fluid delivery device (100) further includes a plunger (120, 225) provided at a first end (125) of the housing (105, 205). The plunger (120, 225) may be coupled to the shaft (110) and may be adapted to move inside the housing (105, 205) to deliver the one or more fluids to the target site (405).
摘要翻译：根据一个实施例，本主题描述了用于将一种或多种流体输送到目标部位的装置。流体输送装置（100）包括壳体（105,205），轴（110），该轴可以设置在壳体（105,205）内以在其间形成至少一个流体腔室（115,210）。此外，流体室（115,210）适于接收一种或多种流体。流体输送装置（100）还包括设置在壳体（105,205）的第一端部（125）处的柱塞（120,225）。柱塞（120,225）可联接到轴（110）并且可适于在壳体（105,205）内移动以将一种或多种流体输送到目标部位（405）。

9. 发明公开

EP2849822A1 DISPENSE INTERFACE FOR AN EJECTION DEVICE 审中-公开
标题翻译：输出接口，用于中，排放装置
公开(公告)号：EP2849822A1
公开(公告)日：2015-03-25
申请号：EP13723764.0
申请日：2013-05-16
申请人： Sanofi-Aventis Deutschland GmbH
发明人： LAUGERE, Frederic , POPA, Cristian , IMPEY, Ben , MACLEOD, Andrew
IPC分类号： A61M5/19
CPC分类号： A61M39/105 , A61M5/19 , A61M5/3294 , A61M5/3295 , A61M5/343 , A61M5/345 , A61M2207/00
摘要： The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet and a part having a body portion and a cover portion; wherein the body portion and the cover portion are connected by a living hinge such that the body portion and the cover portion are foldable towards each other; wherein the body portion and the cover portion are configured to form a fluid channel arrangement between surfaces of the body portion and the cover portion facing each other when the body portion and the cover portion are folded towards each other; wherein the living hinge is arranged next to the facing surfaces; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet.

10. 发明公开

EP2683429A4 RETRACTABLE SYRINGE WITH LOCKING PLUNGER 审中-公开
标题翻译：与制动活塞回缩式注射器
公开(公告)号：EP2683429A4
公开(公告)日：2014-08-27
申请号：EP12754794
申请日：2012-03-06
申请人： MIDLAND MEDICAL DEVICES HOLDINGS LLC
发明人： CAIZZA RICHARD , BOJAN JAY
IPC分类号： A61M5/34 , A61M5/315 , A61M5/50
CPC分类号： A61M5/3234 , A61M5/1782 , A61M5/3295 , A61M5/346 , A61M5/347 , A61M2005/3239

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