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1. 发明公开

EP3378514A1 SYRINGE BARREL, PREFILLED SYRINGE, AND MANUFACTURING METHODS FOR SAME 审中-公开
公开(公告)号：EP3378514A1
公开(公告)日：2018-09-26
申请号：EP16866367.2
申请日：2016-11-17
申请人： Terumo Kabushiki Kaisha
发明人： OKIHARA, Hitoshi
IPC分类号： A61M5/31 , A61M5/28
CPC分类号： A61M5/3134 , A61M5/002 , A61M5/28 , A61M5/31 , A61M2005/3131 , A61M2202/07 , A61M2205/0222 , A61M2207/00
摘要： This manufacturing method for a syringe barrel (12) includes an application step for applying a non-reactive silicone oil (27) to the barrel inner surface (18a) by spraying the silicone oil (27) thereto, and a heating step for heating the applied silicone oil (27) to lower the viscosity thereof. The barrel inner surface (18a) of the syringe barrel (12) is coated with the non-reactive silicone oil (27), which has a viscosity of 3000-30000 cps. The coating ratio of the silicone oil (27) is no higher than 20%.

2. 发明公开

EP3351288A1 NEEDLELESS ACCESS PORT VALVES 审中-公开
公开(公告)号：EP3351288A1
公开(公告)日：2018-07-25
申请号：EP18161804.2
申请日：2010-06-24
申请人： B. Braun Medical Inc.
发明人： BURNARD, Edwin L. , NELSON, David M.
IPC分类号： A61M39/26 , F16K15/14 , F16K51/00 , F16L29/00 , F16L37/28
CPC分类号： F16K15/147 , A61M39/02 , A61M39/26 , A61M2205/0222
摘要： Needleless access port valves are generally discussed herein with particular discussions extended to needleless access port valves incorporating a piston comprising slit along an upper piston section for accommodating fluid flow. The slit opens when the piston is compressed by a medical implement, such as a syringe tip, to permit fluid communication between the inlet and the outlet of the vale housing. The slit may be cut using high frequency cutting machine or a multi-axis robot arm and a cutting blade.

3. 发明公开

EP3323453A1 INTRADERMAL INJECTION NEEDLE FOR IMMUNOTHERAPY 审中-公开
公开(公告)号：EP3323453A1
公开(公告)日：2018-05-23
申请号：EP16824544.7
申请日：2016-07-15
申请人： Terumo Kabushiki Kaisha
发明人： URA Takehiro , SAKATA Kiyoshi , TSUNEDA Sakiko , KOIWAI Kazunori
IPC分类号： A61M5/46 , A61M5/32 , A61M5/34
CPC分类号： A61M5/3291 , A61M5/32 , A61M5/3286 , A61M5/3293 , A61M5/34 , A61M5/46 , A61M2205/0222
摘要： An intradermal injection needle (1) is an intradermal injection needle assembly to be used by piercing the intradermal injection needle into the skin of a living body. The intradermal injection needle (1) has a hollow needle (4) having a blade edge pierceable into the skin and a discharge port (41) of an administration product; and a hub (2) holding the hollow needle. The hollow needle (4) has an outer diameter of 0.15 to 0.20mm. The discharge port (41) has a length of 0.10 to 0.80mm in an axial direction of the hollow needle. When the intradermal injection needle (1) is pierced into the skin of the living body, the discharge port (41) thereof is entirely subcutaneously pierceable within a range of 0.20 to 1.00mm.

4. 发明公开

EP2673025A4 IMPROVEMENTS IN INFUSION SYSTEMS 审中-公开
公开(公告)号：EP2673025A4
公开(公告)日：2018-02-28
申请号：EP12744913
申请日：2012-02-08
申请人： BECTON DICKINSON CO
发明人： SEARLE GARY , HWANG CHARLES
IPC分类号： A61M5/142
CPC分类号： A61M5/162 , A61M5/14216 , A61M5/14228 , A61M5/14244 , A61M5/14248 , A61M5/152 , A61M5/44 , A61M25/0023 , A61M25/02 , A61M37/0092 , A61M39/08 , A61M2205/0222
摘要： An infusion system comprises an infusion set (30) with one or more advanced features including tube set strain relief (10), infusion pumps having heat exchange abilities and two-direction pumping abilities (100), Piezo pump devices (200), reservoirs (220, 240) made from expanded tubing, and oil impregnated pump plungers (302). An exemplary strain relief (10) includes an adhesive layer (12) such as pressure sensitive adhesive (PSA) secured to a base (14). The base (14) rotatably receives a pin (18) of a tube holder (16). The pin (18) is captured within an opening (22) of the base (14) to allow 360 degree rotation of the tube holder (16).

5. 发明授权

EP2527042B1 Device and method for coating elongate objects 有权
标题翻译：用于涂覆细长物体的装置和方法
公开(公告)号：EP2527042B1
公开(公告)日：2018-01-17
申请号：EP12169382.4
申请日：2012-05-24
申请人： Nordson Corporation
发明人： Döker, Andreas , Wanka, Thomas , Wilczek, Michael
IPC分类号： B05B7/04 , B05B7/00 , B05B7/12 , B05B13/02 , A61L31/08 , A61M5/32 , B05D5/08 , B05D1/02 , B05B1/30 , B05B7/10
CPC分类号： A61M5/32 , A61M5/329 , A61M2205/0222 , A61M2205/0238 , A61M2207/10 , B05B7/0012 , B05B7/045 , B05B7/10 , B05B7/12 , B05B13/0207 , B05B13/0214 , B05D1/02 , B05D5/08
摘要： A device (10) for coating an exterior of an elongate object (36) includes a housing structure (22) with an elongate chamber (30) having first and second opposite ends (33, 34). A port (35) communicates with the first end for receiving the elongate object and an outlet is located at the second end. An air supply passage (56) and a coating material supply passage (74) communicate with the elongate chamber. Pressurized air and coating material are adapted to enter the elongate chamber through the air supply passage and the coating material supply passage, respectively, to form a mist in the elongate chamber moving toward the outlet while coating the exterior of the object. A method of coating an exterior surface of the elongate object with the coating material includes holding the elongate object lengthwise in the elongate chamber, mixing the pressurized air and the coating material to form a mist, and coating the exterior surface while directing the mist around the exterior surface and toward the outlet of the elongate chamber.

6. 发明授权

EP2722069B1 SHEATH FOR INTRODUCER AND INTRODUCER ASSEMBLY 有权
标题翻译：介绍人和介绍人汇编
公开(公告)号：EP2722069B1
公开(公告)日：2018-01-03
申请号：EP12801433.9
申请日：2012-04-11
申请人： Terumo Kabushiki Kaisha
发明人： OKAMURA, Ryo
IPC分类号： A61M25/00 , B05D3/00 , B05D5/00 , A61L29/00 , A61L29/14 , A61L29/08 , A61M25/06
CPC分类号： A61M25/0662 , A61L29/041 , A61L29/085 , A61L2400/10 , A61M25/0045 , A61M2025/0046 , A61M2025/0047 , A61M2025/0687 , A61M2205/0222 , C08L33/10 , C08L27/18
摘要： [Problem] To improve the sliding movement of a long body such as a catheter even when the inner diameter of the distal portion of a sheath becomes gradually smaller toward the distal side. [Solution] A sheath (20) for an introducer, which is formed of a sheath tube (21) comprising a hollow portion (21a) through which a elongated body is freely insertable, and which comprises a sheath distal portion (50) and a sheath main body portion (60). The internal diameter (¦a) of the sheath distal portion of the sheath for the introducer becomes gradually smaller toward the distal side. At an inner surface (50a) of the sheath distal portion, the sheath for the introducer comprises a hydrophobic coating (71) which has a friction coefficient lower the a friction coefficient of the sheath tube.

7. 发明公开

EP3061477A1 GASKET USING SLIDABLE MEDICAL SILICONE RUBBER, AND SYRINGE USING SAID GASKET 有权
标题翻译：使用可滑动的医用硅橡胶的垫片和使用所述垫片的注射器
公开(公告)号：EP3061477A1
公开(公告)日：2016-08-31
申请号：EP15848456.8
申请日：2015-04-24
申请人： Coki Engineering Inc.
发明人： YOTSUTSUJI, Akira
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61L31/028 , A61L31/041 , A61L31/048 , A61L31/14 , A61M5/28 , A61M5/315 , A61M2205/0222 , A61M2205/0238 , A61M2205/025 , C08L23/06 , C08L83/04 , C08L2203/02 , C08L2205/14 , C08L2207/068
摘要： A syringe is to be obtained by using PTFE for a gasket main body that makes a direct contact with an injection solution and using a slidable silicone rubber at a portion that does not make contact with the injection solution.
A syringe A includes a syringe barrel 1, a gasket 10 press-fitted within the syringe barrel 1, and a plunger rod 5 mounted in the gasket 10. In the gasket 10, a concaved groove 18 is formed over the whole circumference of a slide-contact surface 11 of a main body portion 26 that is formed of a rigid plastic having a drug solution-resistant property against a drug solution 30 to be loaded in the syringe barrel 1 and that is configured to slidingly contact an inner circumferential surface 2 of the syringe barrel 1. In a slide-contact ring 19 that is to be fitted in the concaved groove 18 and that is configured to slidingly contact the syringe barrel inner circumference surface 2, a silicone oil and a spherical ultrahigh molecular weight fine powder are added to a silicone rubber base material 19c.
摘要翻译：使用PTFE作为与注射液直接接触的垫片主体，在不与注射液接触的部分使用可滑动的硅橡胶，得到注射器。注射器A包括注射器筒1，压配在注射器筒1内的垫圈10以及安装在垫圈10中的柱塞杆5.在垫圈10中，在滑块的整个圆周上形成凹槽18 由具有耐药液性的硬质塑料形成的主体部26的内周面2相对于要装填在注射器用外筒1内的药液30而滑动接触的主体部26的内周面2 注射器筒1中。在要装配在凹槽18中并被配置为滑动地接触注射器筒内周表面2的滑动接触环19中，添加硅油和球形超高分子量细粉末连接到硅橡胶基材19c。

8. 发明授权

EP2910265B1 Gasket for prefilled syringe and prefilled syringe 有权
标题翻译：密封件预充式注射器和预充式注射器
公开(公告)号：EP2910265B1
公开(公告)日：2016-08-31
申请号：EP15151842.0
申请日：2015-01-20
申请人： Sumitomo Rubber Industries, Ltd.
发明人： Hara, Seiji , Nakano, Hiroaki , Kaneko, Hiroyuki , Kondo, Yasuhiko
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61L31/10 , A61L31/14 , A61M5/31515 , A61M2205/0222 , A61M2205/0238

9. 发明授权

EP2460554B1 Nasal delivery device 有权
标题翻译： Nasale Abgabevorrichtungen
公开(公告)号：EP2460554B1
公开(公告)日：2016-06-29
申请号：EP12001127.5
申请日：2007-11-28
申请人： Optinose AS
发明人： Djupesland, Per, Gisle, Dr. , Sheldrake, Colin, David, Dr. , Smith, Simon , Striebig, Rachel , Pidgeon, Andy , St. Quintin, Tom
IPC分类号： A61M16/10 , A61M15/08 , A61M15/00
CPC分类号： A61M15/08 , A61M15/0018 , A61M15/0021 , A61M15/0026 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0043 , A61M15/0081 , A61M15/0098 , A61M16/1045 , A61M2202/064 , A61M2205/0222 , A61M2210/0618 , A61M2210/0625

10. 发明公开

EP3006069A1 GASKET FOR PREFILLED SYRINGE 审中-公开
标题翻译： DICHTUNGFÜRVORGEFÜLLTESPRITZE
公开(公告)号：EP3006069A1
公开(公告)日：2016-04-13
申请号：EP15188759.3
申请日：2015-10-07
申请人： Sumitomo Rubber Industries, Ltd.
发明人： ISHIDA, Naoyuki , NAKANO, Hiroaki , MATSUTANI, Yuichiro , KANEKO, Hiroyuki
IPC分类号： A61M5/315 , B29C33/42 , B29C43/18
CPC分类号： A61M5/31513 , A61M5/31515 , A61M2205/0222 , A61M2205/0238 , A61M2205/19 , B29C43/021 , B29C43/184
摘要： A gasket (10) for a prefilled syringe is provided, which has a generally cylindrical outer shape, and includes a liquid contact portion (13) provided on one of opposite end faces, a thread hole (15) provided in the other end face for attachment of a plunger, and at least two annular projections (17A,17B) provided on a peripheral surface (16) and spaced from each other by an annular trough (18) in a gasket height direction (gasket axial direction) extending from the one end face to the other end face, wherein a diameter difference (A) (= a1 - a2) between a diameter (a1) of the annular projections (17A, 17B) and a diameter (a2) of the annular trough and a diameter difference (B) (= b1 - b2) between a thread root diameter (b1) and a thread ridge diameter (b2) of an internal thread portion of the thread hole satisfy a ratio relationship of A : B = 1 : (2 to 4).
摘要翻译：提供了一种用于预充式注射器的垫圈（10），其具有大致圆柱形的外形，并且包括设置在一个相对端面上的液体接触部分（13），设置在另一端面中的螺纹孔（15）柱塞的安装，以及设置在周面（16）上并且由垫片高度方向（垫片轴向）延伸的环形槽（18）彼此隔开的至少两个环形突起（17A，17B）其特征在于，所述环状凸部（17A，17B）的直径（a1）与所述环状槽的直径（a2）之间的直径差（a）（= a1-a2）螺纹孔的内螺纹部分的螺纹根直径（b1）和螺纹螺纹部分（b2）之间的距离（B）（= b1-b2）满足A:B = 1：（2〜4）。

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