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1. 发明授权

EP1089782B1 SYRINGES AND INJECTORS INCORPORATING MECHANICAL FLUID AGITATION DEVICES 有权
标题翻译： SPLASH和喷油器有机械搅拌
公开(公告)号：EP1089782B1
公开(公告)日：2002-10-02
申请号：EP99944530.7
申请日：1999-08-26
申请人： Schering Aktiengesellschaft
发明人： URICH, Klaus
IPC分类号： A61M5/145 , B01F11/00
CPC分类号： B01F13/005 , A61M1/0204 , A61M5/14546 , B01F11/0002 , B01F11/0017 , B01F11/0022 , B01F13/0052 , B01F2003/0035
摘要： A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. A movement mechanism is operably associated with the injector to move the syringe in such a way that the at least one agitation element agitates a fluid contained in the syringe. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.

2. 发明公开

EP3366327A1 APPARATUS AND METHODS RELATING TO COLLECTING AND PROCESSING HUMAN BIOLOGICAL MATERIAL CONTAINING ADIPOSE 有权转让
公开(公告)号：EP3366327A1
公开(公告)日：2018-08-29
申请号：EP18161782.0
申请日：2011-07-08
申请人： The GID Group, Inc.
发明人： CIMINO, William, W. , KATZ, Adam, J. , LLULL. Ramon
IPC分类号： A61M1/00
CPC分类号： C12N5/0653 , A61M1/0001 , A61M1/0094 , A61M1/0204 , A61M2202/08 , A61M2205/103 , C12M47/04
摘要： A portable apparatus for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material or fat graft material, which access may be via a lumen through a rotatable mixer shaft. Access ports may be configured for access only from above the container. The apparatus is incorporatable into a variety of assemblies, systems, kits, methods and uses.

3. 发明公开

EP1848473A1 PLASMA CONCENTRATOR DEVICE 有权转让
标题翻译：血药浓度DEVICE
公开(公告)号：EP1848473A1
公开(公告)日：2007-10-31
申请号：EP06720110.3
申请日：2006-01-30
申请人： Hanuman LLC , Cell Factor Technologies, Inc.
发明人： DORIAN, Randel , LEACH, Michael, D. , STORRS, Richard, Wood
IPC分类号： A61M1/36 , B01D15/02
CPC分类号： A61M1/3679 , A61M1/0204 , A61M1/3693 , A61M2202/0415 , Y10T436/25375 , Y10T436/255
摘要： A plasma concentrator (2) of this invention having a concentrator chamber (20) , concentrator gel beads (26) , a filter (24) and an agitator (12) . The agitator has agitator blades (34) extending outwardly from the lower end. The agitator end is positioned in the concentrator chamber (20) and supported for rotation about its central axis and for reciprocal movement along its central axis. The method concentrates plasma by removing water without significantly denaturing the fibrinogen in the plasma. The plasma is introduced into the concentration chamber (20) containing a plurality of dehydrated concentrator gel beads (26) and the agitator (12) . Then water is removed from the plasma while stirring the beads to reduce plasma polarization and breaking up clumps of beads that form during the agitation.

4. 发明公开

EP1348456A1 Poche et procédé de défibrination utilisant un élément textile 有权
标题翻译： Beutel und Defibrinierungsverfahren unter Verwendung eines Textilelements
公开(公告)号：EP1348456A1
公开(公告)日：2003-10-01
申请号：EP03290650.5
申请日：2003-03-14
申请人： MACO PHARMA
发明人： Goudaliez, Francis , Verpoort, Thierry
IPC分类号： A61M1/02 , A61J1/14 , B01D39/16
CPC分类号： A61M1/0209 , A61J1/10 , A61J1/1468 , A61J1/1487 , A61M1/0204 , A61M1/0218 , A61M1/025 , A61M1/3636 , A61M1/3672 , A61M1/3679 , A61M2202/0449 , A61M2202/0057
摘要： L'invention a pour objet une poche (1) destinée à la défibrination d'un fluide biologique tel que le sang ou le plasma sanguin, du type comprenant une enveloppe extérieure (2) formant un volume intérieur (6) pour ledit fluide, ladite enveloppe (2) étant munie d'au moins un orifice d'entrée (7) et/ou de sortie (8) du fluide, dans laquelle au moins un élément textile (9) apte à fixer la fibrine du fluide est disposé dans le volume intérieur (6).
L'invention concerne également un système à poches comprenant une telle poche, des procédés de défibrination ainsi que l'utilisation d'un élément textile (9) pour la défibrination d'un fluide biologique.
摘要翻译：设计用于对血液或血浆等生物流体进行去纤维化的袋（1）包括形成用于流体的内部容积（6）的外部外壳（2）。信封具有用于流体的入口（7）和出口（8）。设计成将纤维固定在流体中的织物元件（9）被放置在内部体积中，而不将其细分。设计用于对血液或血浆等生物流体进行去纤维化的袋（1）包括形成用于流体的内部容积（6）的外部外壳（2）。信封具有用于流体的入口（7）和出口（8）。设计成将纤维固定在流体中的织物元件（9）被放置在内部体积中，而不将其细分。纺织元件包括至少一个针织，机织或非织造层，并且由基于聚乙烯，聚丙烯，聚酯，聚酰胺，聚氨酯及其衍生物的聚合物或共聚物制成。外部信封由两个围绕其周边组装的柔软塑料材料的两片叶子（3,3'）制成。纺织元件固定在内部容积的外围的一部分上。还包括以下独立权利要求：（1）设计用于对生物流体如血液或血浆进行取样和去纤维化的小袋系统，其包含如上所述的具有织物元件的初级流体接收袋。第二流体接收袋通过第二管连接到来自主流体接收袋的出口，该第二管包含可以保持微槽的过滤器; 和（2）使用包含如上所述的织物元件的小袋的去纤维化处理，其中袋搅动一段时间，从而有效地消除流体中的所有纤维。脱纤维的流体可以转移到通过密封和无菌手段连接到第一袋的第二袋。停止搅动，使脱纤维血液滗出以分离血清和血细胞。

5. 发明公开

EP2590695A2 APPARATUS AND METHODS RELATING TO COLLECTING AND PROCESSING HUMAN BIOLOGICAL MATERIAL CONTAINING ADIPOSE 有权转让
标题翻译： DEVICE AND METHOD FOR脂肪COVER收集和处理人类的生物材料
公开(公告)号：EP2590695A2
公开(公告)日：2013-05-15
申请号：EP11804445.2
申请日：2011-07-08
申请人： The Gid Group, Inc.
发明人： CIMINO, William, W. , KATZ, Adam, J. , LLULL, Ramon
IPC分类号： A61M1/00
CPC分类号： C12N5/0653 , A61M1/0001 , A61M1/0094 , A61M1/0204 , A61M2202/08 , A61M2205/103 , C12M47/04
摘要： A portable apparatus for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material or fat graft material, which access may be via a lumen through a rotatable mixer shaft. Access ports may be configured for access only from above the container. The apparatus is incorporatable into a variety of assemblies, systems, kits, methods and uses.

6. 发明授权

EP1348456B1 Poche et procédé de défibrination utilisant un élément textile 有权
标题翻译：袋和Defibrinierungsverfahren使用织物元件
公开(公告)号：EP1348456B1
公开(公告)日：2008-10-01
申请号：EP03290650.5
申请日：2003-03-14
申请人： MACO PHARMA
发明人： Goudaliez, Francis , Verpoort, Thierry
IPC分类号： A61M1/02 , A61J1/14 , B01D39/16
CPC分类号： A61M1/0209 , A61J1/10 , A61J1/1468 , A61J1/1487 , A61M1/0204 , A61M1/0218 , A61M1/025 , A61M1/3636 , A61M1/3672 , A61M1/3679 , A61M2202/0449 , A61M2202/0057

7. 发明授权

EP1107804B1 SYRINGES AND INJECTORS INCORPORATING MAGNETIC FLUID AGITATION DEVICES 有权
标题翻译： SPLASH和喷油器，带磁力搅拌器
公开(公告)号：EP1107804B1
公开(公告)日：2002-09-25
申请号：EP99946039.7
申请日：1999-08-26
申请人： SCHERING AKTIENGESELLSCHAFT
发明人： URICH, Klaus
IPC分类号： A61M5/145 , B01F13/08
CPC分类号： A61M5/14546 , A61M1/0204 , A61M5/14566 , B01F13/08
摘要： A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. The agitation element is acted on by a magnetic field to agitate the contents of the syringe. The magnetic field is generated by a source operably associated with the syringe or the injector. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.

8. 发明公开

EP2590695A4 APPARATUS AND METHODS RELATING TO COLLECTING AND PROCESSING HUMAN BIOLOGICAL MATERIAL CONTAINING ADIPOSE 有权转让
标题翻译： VORRICHTUNG UND VERFAHREN ZUR ERHEBUNG UND VERARBEITUNG VON MENSCHLICHEM BIOLOGISCHEM材料MIT FETTGEWEBE
公开(公告)号：EP2590695A4
公开(公告)日：2017-09-06
申请号：EP11804445
申请日：2011-07-08
申请人： THE GID GROUP INC
发明人： CIMINO WILLIAM W , KATZ ADAM J , LLULL RAMON
IPC分类号： A61M1/00
CPC分类号： C12N5/0653 , A61M1/0001 , A61M1/0094 , A61M1/0204 , A61M2202/08 , A61M2205/103 , C12M47/04

9. 发明授权

EP1848473B1 PLASMA CONCENTRATOR DEVICE 有权转让
标题翻译： PLASMAKONZENTRATIONSVORRICHTUNG
公开(公告)号：EP1848473B1
公开(公告)日：2013-05-22
申请号：EP06720110.3
申请日：2006-01-30
申请人： Hanuman LLC , Biomet Biologics, LLC
发明人： DORIAN, Randel , LEACH, Michael, D. , STORRS, Richard, Wood
IPC分类号： A61M1/36 , B01D15/02
CPC分类号： A61M1/3679 , A61M1/0204 , A61M1/3693 , A61M2202/0415 , Y10T436/25375 , Y10T436/255

10. 发明公开

EP1107804A1 SYRINGES AND INJECTORS INCORPORATING MAGNETIC FLUID AGITATION DEVICES 有权
标题翻译： SPLASH和喷油器，带磁力搅拌器
公开(公告)号：EP1107804A1
公开(公告)日：2001-06-20
申请号：EP99946039.7
申请日：1999-08-26
申请人： SCHERING AKTIENGESELLSCHAFT
发明人： URICH, Klaus
IPC分类号： A61M5/145 , B01F13/08
CPC分类号： A61M5/14546 , A61M1/0204 , A61M5/14566 , B01F13/08
摘要： A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. The agitation element is acted on by a magnetic field to agitate the contents of the syringe. The magnetic field is generated by a source operably associated with the syringe or the injector. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.

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