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1. 发明授权

EP2910258B1 PLATELET RICH PLASMA CONCENTRATE APPARATUS 有权
公开(公告)号：EP2910258B1
公开(公告)日：2018-08-01
申请号：EP15159104.7
申请日：2006-01-30
申请人： Hanuman LLC , Biomet Biologics, LLC
发明人： Dorian, Randel , Leach Michael
IPC分类号： A61M1/02 , A61M1/34 , A61M1/36 , B01D63/02 , B04B5/04
CPC分类号： B01D63/02 , A61M1/0281 , A61M1/3482 , A61M1/3496 , A61M1/3633 , A61M1/3679 , A61M1/3693 , A61M1/3696 , A61M2202/0415 , A61M2202/0427 , B01D2313/44 , B01D2313/58 , B04B5/0442 , B04B2005/0478
摘要： The PRP separator-concentrator of this invention is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly (2), and a concentrator assembly (44). The centrifugal separator assembly comprises a centrifugal drum (5)separator that includes an erythrocyte capture module and a motor (4) having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate. The centrifugal drum separator has an erythrocyte trap. The water removal module can be a syringe (44) device with water absorbing beads.

2. 发明公开

EP3236259A1 PLASMA OR SERUM PRODUCTION AND REMOVAL OF FLUIDS UNDER REDUCED PRESSURE 审中-公开
标题翻译：等离子或血清生产和在减压下去除流体
公开(公告)号：EP3236259A1
公开(公告)日：2017-10-25
申请号：EP17163266.4
申请日：2012-04-26
申请人： Seventh Sense Biosystems, Inc.
发明人： HAGHGOOIE, Ramin , CHICKERING III, Donald E , DAVIS, Shawn , MICHELMAN, Mark , BERNSTEIN, Howard , HORTON, Kristin
IPC分类号： G01N33/49 , A61B5/145 , A61B5/151 , A61B5/154 , A61B5/15 , A61M1/36 , A61B5/1455 , A61B5/1486 , B01L3/00 , A61M1/34 , A61B10/00
CPC分类号： A61B5/150099 , A61B5/1411 , A61B5/1438 , A61B5/14514 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150419 , A61B5/150503 , A61B5/150755 , A61B5/150969 , A61B5/150984 , A61B5/151 , A61B5/15105 , A61B5/15142 , A61B5/154 , A61B10/0045 , A61B2562/0295 , A61M1/34 , A61M1/3486 , A61M1/3687 , A61M2202/0415 , A61M2205/3334 , B01L3/502753 , B01L2300/0672 , B01L2300/0681 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2400/049 , B01L2400/0655 , B01L2400/0688 , G01N33/18 , G01N33/1826
摘要： The application relates a device and a method for receiving blood from a subject and processing the blood to form plasma or serum. The device comprises: an inlet (42) for introduction of blood from the subject into the device; a separation membrane (50) in fluid communication with the inlet on a first side of the membrane, the separation membrane being capable of separating blood passing therethrough into a first portion that is enriched in plasma or serum, and a rejected portion concentrated in blood cells; and a pre-packaged vacuum chamber (35) having a pressure less than ambient pressure prior to the point at which the device is used on the subject, the vacuum chamber being in gaseous communication with a second side of the membrane; wherein the device comprises a first module and a second module removable from the first module, wherein the second module comprises a storage chamber for receiving the first portion of blood enriched in plasma or serum.
摘要翻译：本申请涉及用于从受试者接收血液并处理血液以形成血浆或血清的装置和方法。该装置包括：用于将血液从受试者引入装置中的入口（42）与膜的第一侧上的入口流体连通的分离膜（50），分离膜能够将通过其中的血液分离成富含血浆或血清的第一部分和浓缩在血细胞中的排斥部分 ; 以及预先封装的真空室（35），其在所述装置在所述对象上使用的点之前具有低于环境压力的压力，所述真空室与所述膜的第二侧气体连通; 其中所述装置包括第一模块和可从所述第一模块移除的第二模块，其中所述第二模块包括用于接收富含血浆或血清的第一部分血液的储存室。

3. 发明公开

EP2932990A4 DEVICE FOR SEPARATING/HOUSING BLOOD COMPONENTS AND METHOD FOR PREPARING PLATELET-RICH PLASMA 审中-公开
标题翻译： DEVICE FOR切割/取血组件和方法用于富含血小板的血浆生产
公开(公告)号：EP2932990A4
公开(公告)日：2016-10-19
申请号：EP13861967
申请日：2013-12-11
申请人： JMS CO LTD
发明人： OKAMOTO YASUNORI , TANAKA SEISHIN , OGATA KASUMI
IPC分类号： A61M1/02 , A61K35/14 , A61M1/36 , A61P17/02 , A61P17/16 , A61P19/08
CPC分类号： A61M1/36 , A61K35/14 , A61M1/02 , A61M1/3621 , A61M1/3698 , A61M2202/0413 , A61M2202/0415 , A61M2202/0427
摘要： Provided are: a device that is for separating/housing blood components and that can more easily and aseptically separate/house platelet-rich plasma; and a method for preparing platelet-rich plasma. The device (1) for separating/housing blood components is provided with: a blood storage section (2); a component housing section (3) for housing a component that is part of blood; and a linking tube (4) that joins the blood storage section (2) and the component housing section (3). The blood storage section (2) has: a tube-shaped blood storage vessel (21) that is flexible; a blood lead-in pathway (27) that leads blood into the blood storage vessel (21); and a component lead-out pathway (28) that leads out a component that is part of blood from the blood storage vessel (21). The component housing section (3) has: a component lead-in pathway (37) that leads in a component that is part of blood led out from the blood storage vessel (21); and a metal needle (371) that extends from the component lead-in pathway (37) towards the interior space of the component housing section (3) and can return the component that is part of blood housed in the component housing section (3) towards the blood storage vessel (21).

4. 发明公开

EP3034114A1 SYSTEM AND METHOD FOR THE RE-ANTICOAGULATION OF PLATELET RICH PLASMA 有权
标题翻译： VERFAHREN ZUR ERNEUTEN ANTIKOAGULATION VONBLUTPLÄTTCHEN-REICHEM PLASMA系统
公开(公告)号：EP3034114A1
公开(公告)日：2016-06-22
申请号：EP15203263.7
申请日：2010-03-04
申请人： Haemonetics Corporation
发明人： PAGES, Etienne , RAGUSA, Michael
IPC分类号： A61M1/36 , A61M1/38 , A61M1/02
CPC分类号： A61M1/3672 , A61M1/0209 , A61M1/0218 , A61M1/288 , A61M1/3603 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3693 , A61M1/38 , A61M1/382 , A61M2005/1402 , A61M2005/1403 , A61M2202/0071 , A61M2202/0413 , A61M2202/0415 , A61M2202/0427 , A61M2205/3379 , A61M2205/75 , B01D2221/10
摘要： A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.
摘要翻译：用于血液分离系统中血小板富集血浆的再抗凝的方法包括用抗凝血剂引发血液分离系统，使得一定量的抗凝血剂转移到PRP容器中。然后，该方法可以将PRP容器内的抗凝血剂转移到红细胞容器中，并在PRP容器内收集一定体积的富含血小板的血浆。可以以多个周期收集富血小板血浆。在收集周期之间，该方法可以将抗凝血剂的一部分体积从红细胞容器转移到PRP容器。

5. 发明公开

EP2910258A3 PLATELET RICH PLASMA CONCENTRATE APPARATUS 审中-公开
标题翻译： VORRICHTUNGFÜRBLUTPLÄTTCHENREICHESPLASMAKONZENTRAT
公开(公告)号：EP2910258A3
公开(公告)日：2015-11-25
申请号：EP15159104.7
申请日：2006-01-30
申请人： Hanuman LLC , Biomet Biologics, LLC
发明人： Dorian, Randel , Leach Michael
IPC分类号： A61M1/02 , A61M1/34 , A61M1/36 , B01D63/02 , B04B5/04
CPC分类号： B01D63/02 , A61M1/0281 , A61M1/3482 , A61M1/3496 , A61M1/3633 , A61M1/3679 , A61M1/3693 , A61M1/3696 , A61M2202/0415 , A61M2202/0427 , B01D2313/44 , B01D2313/58 , B04B5/0442 , B04B2005/0478
摘要： A PRP separator-concentrator comprising a housing (2), a separation assembly, and a concentration assembly. The concentration assembly has a concentration sump (162). An axially concentric rigid stationary outlet tube is secured to the housing and extends through the separation assembly to the sump. The separation assembly is attached to and positioned above the concentration assembly to form a combined separator-concentrator assemblage that is rotatable about the outlet tube. The separation assembly includes a separation chamber lined with a depth filter having pores and passageways that are sized to receive and entrap erythrocytes during centrifuging. The concentration chamber has a floor for supporting desiccated beads and a wall with at least one opening closed with a screen (188). PRP concentrate is produced by contacting PRP with desiccated beads (19) while the beads are stirred with a stationary rake, and rotating the concentration chamber at centrifugal speeds to separate PRP concentrate from the beads.
摘要翻译：本发明的PRP分离器集中器适用于创伤受害者的办公用途或紧急使用。 PRP分离器包括电动离心分离组件（2）和集中器组件（44）。离心分离器组件包括离心鼓（5）分离器，其包括红细胞捕获模块和具有连接到离心鼓分离器的驱动轴的马达（4）。浓缩器组件包括用于制备PRP浓缩物的去水模块。离心鼓分离器具有红细胞捕集器。除水模块可以是具有吸水珠的注射器（44）装置。

6. 发明公开

EP2932990A1 DEVICE FOR SEPARATING/HOUSING BLOOD COMPONENTS AND METHOD FOR PREPARING PLATELET-RICH PLASMA 审中-公开
标题翻译： DEVICE FOR切割/取血组件和方法用于富含血小板的血浆生产
公开(公告)号：EP2932990A1
公开(公告)日：2015-10-21
申请号：EP13861967.1
申请日：2013-12-11
申请人： JMS Co., Ltd.
发明人： OKAMOTO, Yasunori , TANAKA, Seishin , OGATA, Kasumi
IPC分类号： A61M1/02 , A61K35/14 , A61P17/02 , A61P17/16 , A61P19/08
CPC分类号： A61M1/36 , A61K35/14 , A61M1/02 , A61M1/3621 , A61M1/3698 , A61M2202/0413 , A61M2202/0415 , A61M2202/0427
摘要： Provided are: a device that is for separating/housing blood components and that can more easily and aseptically separate/house platelet-rich plasma; and a method for preparing platelet-rich plasma. The device (1) for separating/housing blood components is provided with: a blood storage section (2); a component housing section (3) for housing a component that is part of blood; and a linking tube (4) that joins the blood storage section (2) and the component housing section (3). The blood storage section (2) has: a tube-shaped blood storage vessel (21) that is flexible; a blood lead-in pathway (27) that leads blood into the blood storage vessel (21); and a component lead-out pathway (28) that leads out a component that is part of blood from the blood storage vessel (21). The component housing section (3) has: a component lead-in pathway (37) that leads in a component that is part of blood led out from the blood storage vessel (21); and a metal needle (371) that extends from the component lead-in pathway (37) towards the interior space of the component housing section (3) and can return the component that is part of blood housed in the component housing section (3) towards the blood storage vessel (21).
摘要翻译：本发明提供：装置所做的是，用于分离/壳体的血液成分和做了更多能够容易且无菌地分离/房子富含血小板的血浆; 和用于制备富含血小板的血浆的方法。用于分离/壳体血液成分的装置（1）设置有：血液储存部（2）; 用于容纳一个组件做了元件容纳部（3）是血液的一部分; 和一个连接管（4）没有加入血液存储部（2）和所述部件壳体部（3）。血液存储部（2）具有：筒状的血液贮存容器（21）是柔性的; 血液导入通路（27）确实导致血液进入血液贮存容器（21）; 并且组件引出通路（28）做了引出的成分所做的是从血液贮存容器（21）的血液部分。在元件容纳部（3）具有：一个部件导入通路（37）做在一个部件引线确实是血液从血液贮存容器（21）中引出部分; 和金属针（371）确实从朝向所述元件容纳部（3）的内部空间中的部件导入通路（37）延伸，并且可以返回部件所做的是在元件容纳部坐落的血液部分（3）朝向血液贮存容器（21）。

7. 发明公开

EP2910258A2 PLATELET RICH PLASMA CONCENTRATE APPARATUS 审中-公开
标题翻译：富含血小板的等离子体浓缩设备
公开(公告)号：EP2910258A2
公开(公告)日：2015-08-26
申请号：EP15159104.7
申请日：2006-01-30
申请人： Hanuman LLC , Biomet Biologics, LLC
发明人： Dorian, Randel , Leach Michael
IPC分类号： A61M1/02 , A61M1/34 , A61M1/36 , B01D63/02 , B04B5/04
CPC分类号： B01D63/02 , A61M1/0281 , A61M1/3482 , A61M1/3496 , A61M1/3633 , A61M1/3679 , A61M1/3693 , A61M1/3696 , A61M2202/0415 , A61M2202/0427 , B01D2313/44 , B01D2313/58 , B04B5/0442 , B04B2005/0478
摘要： A PRP separator-concentrator comprising a housing (2), a separation assembly, and a concentration assembly. The concentration assembly has a concentration sump (162). An axially concentric rigid stationary outlet tube is secured to the housing and extends through the separation assembly to the sump. The separation assembly is attached to and positioned above the concentration assembly to form a combined separator-concentrator assemblage that is rotatable about the outlet tube. The separation assembly includes a separation chamber lined with a depth filter having pores and passageways that are sized to receive and entrap erythrocytes during centrifuging. The concentration chamber has a floor for supporting desiccated beads and a wall with at least one opening closed with a screen (188). PRP concentrate is produced by contacting PRP with desiccated beads (19) while the beads are stirred with a stationary rake, and rotating the concentration chamber at centrifugal speeds to separate PRP concentrate from the beads.
摘要翻译：一种PRP分离浓缩器，包括壳体（2），分离组件和浓缩组件。浓度组件具有浓缩池（162）。轴向同心的刚性静止出口管固定在壳体上并通过分离组件延伸到贮槽。分离组件连接并定位在浓缩组件上方以形成可围绕出口管旋转的组合的分离器 - 浓缩器组件。分离组件包括衬有深度过滤器的分离室，所述深度过滤器具有孔和通道，所述孔和通道的尺寸设定为在离心期间接收和截留红细胞。浓缩室具有用于支撑干燥小珠的底板和具有至少一个用筛网封闭的开口的壁（188）。通过使PRP与干燥珠粒（19）接触来生产PRP浓缩物，同时用固定耙子搅拌珠粒，并且以离心速度旋转浓缩室以从珠粒中分离PRP浓缩物。

8. 发明授权

EP1129291B1 PROGRAMMABLE, FLUID PRESSURE ACTUATED BLOOD PROCESSING SYSTEMS 有权
标题翻译：可编程借助液压CONFIRMED血液处理系统的
公开(公告)号：EP1129291B1
公开(公告)日：2014-12-17
申请号：EP00964955.9
申请日：2000-08-29
申请人： Fenwal, Inc.
发明人： WESTBERG, Tom , VISHNOI, Rohit , VANDLIK, Mark, R.
IPC分类号： F04B49/00
CPC分类号： F04B43/026 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3696 , A61M2202/0415 , A61M2202/0429 , A61M2205/128 , A61M2205/331 , A61M2205/3393 , F04B13/02 , F04B49/065 , F04B2205/09

9. 发明公开

EP2763718A1 DIALYSEVORRICHTUNG SOWIE VERFAHREN ZUM BETREIBEN DERSELBEN 审中-公开
公开(公告)号：EP2763718A1
公开(公告)日：2014-08-13
申请号：EP12741329.2
申请日：2012-07-30
申请人： Kleophas, Werner
发明人： Kleophas, Werner
IPC分类号： A61M1/16 , A61M1/34
CPC分类号： A61M1/3639 , A61M1/14 , A61M1/16 , A61M1/342 , A61M1/3437 , A61M1/3441 , A61M1/3468 , A61M1/3482 , A61M2202/0415 , A61M2205/3331 , A61M2205/50
摘要： The invention relates to a dialysis device and to a method for operating a dialysis device. A dialysis device according to the invention has a hemodialyzer (10) that can be connected to the blood circuit of a patient, a plasma storage unit (40) for temporarily storing blood plasma of the patient, and a feeding unit (31, 32, 35, 50) for feeding blood plasma stored in the plasma storage unit (40) into the blood circuit of the patient.
摘要翻译：根据本发明的透析装置包括可连接到患者的血液循环的血液透析器，用于临时存储患者血浆的等离子体存储装置和用于将存储在等离子体存储装置中的血浆供应到供给装置的供给装置患者血液循环

10. 发明授权

EP2168605B1 Device for pathogen inactivation of therapeutic fluids with sterilizing radiation 有权
标题翻译：一种用于灭活存在于治疗性流体病原体用杀菌辐射装置
公开(公告)号：EP2168605B1
公开(公告)日：2014-04-16
申请号：EP09075485.4
申请日：2001-01-26
申请人： Baxter International Inc.
发明人： Breillatt, Julian , Woo, Lecon , Sandford, Craig , Boggs, Daniel R. , Khare, Atul , Sternberg, Shmuel
IPC分类号： A61L2/02 , A61M1/36 , A61L2/10 , A61L2/00 , A61M1/02
CPC分类号： A61L2/10 , A61L2/0011 , A61M1/0281 , A61M1/3681 , A61M2202/0415 , A61M2205/053

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