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1. 发明授权

EP2604289B1 RADIAL SHAPE OF POLYMER COMPOUND CONTAINING IODINE, PREPARATION METHOD THEREOF, AND CT CONTRAST MEDIUM COMPOSITION CONTAINING SAME 失效
标题翻译：包含碘的聚合物复合物的径向形状，其制备方法以及包含该组合物的CT对比介质组合物
公开(公告)号：EP2604289B1
公开(公告)日：2017-08-16
申请号：EP11816662.8
申请日：2011-08-16
申请人： Korea Research Institute of Bioscience and Biotechnology
发明人： KIM, Yoonkyung , KIM, Dong-Eog , JUNG, Hye-Youn , CHOE, Yun Hui
IPC分类号： A61K49/12 , A61K49/14 , A61K49/10 , A61K49/04
CPC分类号： A61K51/06 , A61K49/0442

2. 发明公开

EP2600902A4 RADIOPAQUE SHAPE MEMORY POLYMERS FOR MEDICAL DEVICES 审中-公开
标题翻译： RÖNTGENDICHTEFORMSPEICHERNDE POLYMEREFÜRMEDISINISCHE VORRICHTUNGEN
公开(公告)号：EP2600902A4
公开(公告)日：2015-01-07
申请号：EP11815394
申请日：2011-08-05
申请人： ENDOSHAPE INC
发明人： GOODRICH STEPHEN DEAN , LYONS MICHAEL , CASTLEBERRY JEFFREY PAUL
IPC分类号： A61K49/04
CPC分类号： C08F222/20 , A61K49/0442 , C08F214/16 , C08F222/1006 , C08F222/12 , C08F263/02 , C08F2218/20 , C08G2280/00 , C08L2201/12
摘要： Radiopaque polymer compositions and methods for making the compositions are provided. These radiopaque polymer compositions include shape memory polymer compositions comprising a crosslinked polymer network, the network comprising a first repeating unit derived from a monofunctional iodinated monomer and a second repeating unit derived from a multifunctional non-iodinated monomer wherein neither of the two monomers is fluorinated. Devices formed from radiopaque polymer compositions are also provided.
摘要翻译：提供不透射线的聚合物组合物和制备组合物的方法。这些不透射线的聚合物组合物包括包含交联聚合物网络的形状记忆聚合物组合物，该网络包含衍生自单官能碘化单体的第一重复单元和衍生自多官能非碘化单体的第二重复单元，其中两种单体都不是氟化的。还提供了由不透射线的聚合物组合物形成的装置。

3. 发明公开

EP2512540A4 IMPLANTS AND BIODEGRADABLE FIDUCIAL MARKERS 有权转让
标题翻译：植入物和可生物降解符号说明
公开(公告)号：EP2512540A4
公开(公告)日：2013-08-14
申请号：EP10842525
申请日：2010-12-15
申请人： INCEPT LLC
发明人： CAMPBELL PATRICK , SAWHNEY AMARPREET S
IPC分类号： A61L27/50 , A61L27/14 , A61L27/54 , A61L27/58 , A61L31/12
CPC分类号： A61K49/0442 , A61K49/0419 , A61K51/1244 , A61K2123/00 , A61L27/50 , A61L27/52 , A61L27/58 , A61L31/145 , A61L31/148 , A61L31/18
摘要： A pharmaceutically acceptable implant system comprising a collection of pharmaceutically acceptable, covalently-crosslinked hydrogel particles having a radioopaque agent covalently attached to a plurality of the particles in the collection, with the radioopaque agent being present in the collection at a concentration of at least about 0.1% w/w. The implantable materials may be used, for instance, in an iatrogenic site and for fiducial marking.

4. 发明公开

EP2451488A2 MULTIMODAL VISIBLE POLYMER EMBOLIZATION MATERIAL 审中-公开
标题翻译：多式联运可见栓塞聚合物
公开(公告)号：EP2451488A2
公开(公告)日：2012-05-16
申请号：EP10740173.9
申请日：2010-07-06
申请人： Bartling, Sönke
发明人： MARGEL, Shlomo , AVIV, Hagit
IPC分类号： A61K49/00 , A61K49/04 , A61K49/18 , A61K49/22 , A61K51/12
CPC分类号： A61K49/0002 , A61B5/0035 , A61B5/0515 , A61B5/416 , A61B6/5235 , A61B6/5247 , A61B8/4281 , A61B8/4416 , A61K49/0419 , A61K49/0438 , A61K49/0442 , A61K49/048 , A61K49/1821 , A61K49/225 , A61K51/1244 , B82Y5/00
摘要： The present invention relates to embolization material for therapeutic use, wherein said material is visible via more than one imaging technique.

5. 发明公开

EP1989178A1 CONTRAST AGENTS 有权
标题翻译：对比剂
公开(公告)号：EP1989178A1
公开(公告)日：2008-11-12
申请号：EP07709227.8
申请日：2007-02-13
申请人： GE Healthcare AS
发明人： PRIEBE, Hanno
IPC分类号： C07C237/32 , A61K49/04
CPC分类号： C07C237/46 , A61K49/0442
摘要： The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a hydrophilic aliphatic central moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.
摘要翻译：本发明涉及一类化合物和含有这些化合物的诊断组合物，其中化合物是含碘化合物。更具体地说，含碘化合物是含有亲水脂肪族中心部分的化合物，允许三个碘代苯基键合到其上。本发明还涉及这种诊断组合物作为造影剂在诊断成像中，特别是在X射线成像中的用途以及含有这些化合物的造影剂的用途。

6. 发明公开

EP1815871A3 Radiographic contrasting agents and radio-opaque polymeric materials for medical devices 有权
标题翻译： X射线造影剂和用于医疗装置的不透射线的聚合物材料
公开(公告)号：EP1815871A3
公开(公告)日：2007-12-26
申请号：EP06256292.1
申请日：2006-12-11
申请人： Cordis Corporation
发明人： Zhao, Jonathon Z.
IPC分类号： A61K49/00 , A61L31/18 , A61K49/04
CPC分类号： A61K49/0438 , A61K49/0442 , A61L17/06 , A61L17/145 , A61L27/34 , A61L27/58 , A61L31/10 , A61L31/148 , A61L31/18 , C07H13/08 , C07H17/02
摘要： The present invention discloses a radiographic contrasting agent containing multiple aromatic groups, each of which is substituted with at least three halogen atoms. The radiographic contrasting agent can initiate a polymerization process. The present invention also discloses a radio-opaque polymeric material that comprises a biodegradable polymer having at least one radiographic contrasting moiety covalently attached thereto. The radio-opaque polymeric material provides enhanced contrasting intensity in radiographic imaging. The radio-opaque polymeric material can be applied on at least a portion of one surface of a medical device. The radio-opaque polymeric material can also be used to construct a medical device, a component thereof, or a portion of a component thereof.

7. 发明授权

EP1036057B1 RADIO-OPAQUE POLYMER BIOMATERIALS 有权
标题翻译：辐射半透明的聚合物生物材料
公开(公告)号：EP1036057B1
公开(公告)日：2005-10-19
申请号：EP98959390.0
申请日：1998-11-06
申请人： Rutgers, The State University
发明人： KOHN, Joachim, B. , BOLIKAL, Durgadas , PENDHARKAR, Sanyog, M.
IPC分类号： C07C229/00 , C08G63/00 , C08G63/06 , C08L69/00 , C08L77/04 , C07K14/00 , C08G63/685 , C08G64/12 , C08G64/16 , C08G69/44
CPC分类号： C08G64/12 , A61K9/204 , A61K38/00 , A61K49/0438 , A61K49/0442 , A61K49/0447 , A61L31/10 , A61L31/16 , A61L31/18 , A61L2300/00 , C08G63/672 , C08G63/6826 , C08G63/6856 , C08G64/10 , C08G64/1633 , C08G64/1641 , C08G64/183 , C08G65/3317 , C08G69/44 , C08K5/13 , C08K5/20

8. 发明授权

EP1059943B1 IMPLANTABLE PARTICLES FOR TISSUE BULKING AND THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE, URINARY INCONTINENCE, AND SKIN WRINKLES 有权
标题翻译：植入粒子增大音量，组织进行治疗GASTROÖSOPHAGALREFLUX，尿失禁和皮褶
公开(公告)号：EP1059943B1
公开(公告)日：2004-12-01
申请号：EP99909789.2
申请日：1999-03-04
申请人： Biosepra Medical Inc.
发明人： VOGEL, Jean, Marie , THOMAS, Richard , BOSCHETTI, Egisto
IPC分类号： A61K47/48 , A61K9/16 , A61P3/04 , A61P13/00 , A61P17/00
CPC分类号： A61K9/0034 , A61K9/1635 , A61K9/1641 , A61K47/62 , A61K47/6927 , A61K49/0442 , A61K49/048
摘要： The invention encompasses the treatment of urinary incontinence, gastroesophageal reflux disease and the amelioration of skin wrinkles using biocompatible hydrophilic cationic microparticles and a cell adhesion promoter.

9. 发明公开

EP1059943A1 IMPLANTABLE PARTICLES FOR TISSUE BULKING AND THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE, URINARY INCONTINENCE, AND SKIN WRINKLES 有权
标题翻译：植入粒子增大音量，组织进行治疗GASTROÖSOPHAGALREFLUX，尿失禁和皮褶
公开(公告)号：EP1059943A1
公开(公告)日：2000-12-20
申请号：EP99909789.2
申请日：1999-03-04
申请人： Biosepra Medical Inc.
发明人： VOGEL, Jean, Marie , THOMAS, Richard , BOSCHETTI, Egisto
IPC分类号： A61K47/48 , A61K9/16
CPC分类号： A61K9/0034 , A61K9/1635 , A61K9/1641 , A61K47/62 , A61K47/6927 , A61K49/0442 , A61K49/048
摘要： The invention encompasses the treatment of urinary incontinence, gastroesophageal reflux disease and the amelioration of skin wrinkles using biocompatible hydrophilic cationic microparticles and a cell adhesion promoter.

10. 发明授权

EP0782563B1 COMPOSES POLYIODES, LEUR PREPARATION ET LEUR APPLICATION EN RADIOLOGIE X 失效
标题翻译： IODO化合物，其生产和使用造影剂进行X光放射学
公开(公告)号：EP0782563B1
公开(公告)日：1999-06-23
申请号：EP95932034.2
申请日：1995-09-20
申请人： GUERBET
发明人： LE LEM, Gael , MEYER, Dominique
IPC分类号： C07C237/46 , A61K49/04
CPC分类号： A61K49/0442 , C07C237/46
摘要： Contrast agents for X-ray radiology having formula (I), wherein Ti, Vi, T'i, V'i, where i = 0, 1 or 2, are O, COND or NDCO where D is H, alkyl or hydroxyalkyl; Qi and Q'i, where i = 0, 1 or 2, are alkylene or hydroxyalkylene; Ari and Ar'i, where i = 1 or 2, are (II) or (III), wherein R, R3 and R4 are COOH, and R', R'3 and R'4 are CONR'1R'2 or N(R'1)COR'2 where R'1 and R'2 are H, C1-4 alkyl or hydroxyalkyl together comprising more than 4 OH, or R1 and R'i, where i = 0, 3 or 4, are CONR'1R'2 and N(R'1)COR'2, R'1 and R'2 together comprising at least 6 OH; or else are T-Q-V-Ar where T, Q and V may have the previous meanings and Ar has formula (II); and A is the residue of a molecule having a molar mass of less than 1200 and comprising two bonds capable of forming an amide or etheroxide group with T0 and T'0.

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