专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP3129075B1 BONE REPAIR COMPOSITIONS 有权
公开(公告)号：EP3129075B1
公开(公告)日：2024-09-18
申请号：EP15777375.5
申请日：2015-04-09
IPC分类号： A61L27/38 , A61K35/12 , A61K35/28 , A61K31/728 , C12M1/00
CPC分类号： A61K31/728 , A61K35/28 , A61K35/44 , A61L27/12 , A61L27/58 , A61L27/3608 , A61L27/3808 , A61L27/3834 , A61L27/46 , A61L2430/0220130101

3. 发明公开

EP4382111A1 EXTRACELLULAR VESICLES THAT PROMOTE ANGIOGENESIS OR NEOVASCULARISATION 审中-公开
公开(公告)号：EP4382111A1
公开(公告)日：2024-06-12
申请号：EP22386089.1
申请日：2022-12-09
申请人： The University Court Of The University of Edinburgh
发明人： Kesidou, Despoina , Beqqali, Abdelaziz , Baker, Andrew , Brittan, Mairi , Mountford, Joanne
IPC分类号： A61K35/545 , A61P9/00 , A61K35/12 , A61K35/44 , A61L27/54 , A61P9/10 , A61P9/12 , A61P11/00 , A61P17/02 , B01D15/34
CPC分类号： A61K35/12 , A61K35/44 , A61K35/545 , A61L27/54 , B01D15/34 , A61P9/00 , A61P9/10 , A61P17/02 , A61P11/00 , A61P9/12 , A61L31/16 , A61L2300/62620130101 , A61L2300/6420130101
摘要： The present disclosure relates to extracellular vesicles (EVs) (and their contents) from a pluripotent stem-cell derived endothelial cell product (ECP); as well as their isolation; uses and methods employing the EVs in therapy, such as in promoting angiogenesis and/or neovascularisation.

4. 发明授权

EP2894218B1 MEDIUM, FOR CULTURING CORNEAL ENDOTHELIAL CELLS, CONTAINING CONDITIONED MEDIUM FROM MESENCHYMAL STEM CELLS 有权
公开(公告)号：EP2894218B1
公开(公告)日：2018-09-12
申请号：EP13835476.6
申请日：2013-09-05
申请人： JCR Pharmaceuticals Co., Ltd. , The Doshisha , Kyoto Prefectural Public University Corporation
发明人： HAGIYA, Michio , IMAGAWA, Kiwamu , HOSODA, Yuuki , KOIZUMI, Noriko , OKUMURA, Naoki , NAKAHARA, Makiko , KINOSHITA, Shigeru
IPC分类号： C12N5/079 , A61K35/30 , A61P27/02
CPC分类号： C12N5/0621 , A61K35/30 , A61K35/44 , C12N5/0018 , C12N2500/84 , C12N2502/1358
摘要： [Problem]To provide, in order to manufacture cells to transplant into patients with corneal endothelial failure, a medium used to culture corneal endothelial cells obtained from human corneal tissue and grow said cells while maintaining the morphology thereof as corneal endothelial cells. [Solution] A medium containing a conditioned medium from mesenchymal stem cells; and a method in which said medium is used to culture corneal endothelial cells.

5. 发明授权

EP2826855B1 MYOCARDIAL SHEET 有权转让
公开(公告)号：EP2826855B1
公开(公告)日：2018-08-29
申请号：EP13760866.7
申请日：2013-03-15
申请人： iHeart Japan Corporation
发明人： YAMASHITA, Jun , MASUMOTO, Hidetoshi
IPC分类号： C12N5/071 , A61K35/12 , A61L27/00 , A61P9/00
CPC分类号： A61L27/3886 , A61K35/34 , A61K35/44 , A61K35/545 , A61L27/3804 , A61L27/3808 , A61L27/3826 , A61L27/3834 , A61L27/3839 , A61L27/3895 , A61L27/50 , A61L27/54 , A61L2300/608 , A61L2300/64 , A61L2430/20 , C12N5/0602 , C12N5/0657 , C12N5/069 , C12N5/0697 , C12N2500/44 , C12N2501/115 , C12N2501/16 , C12N2501/165 , C12N2501/727 , C12N2502/1329 , C12N2502/28 , C12N2506/45 , C12N2539/10 , A61K2300/00
摘要： The present invention provides: a method for producing mixed cells comprising cardiomyocytes, endothelial cells and mural cells from induced pluripotent stem cells, the method comprising (a) a step of producing cardiomyocytes from induced pluripotent stem cells and (b) a step of culturing the cardiomyocytes in the presence of VEGF; and a therapeutic agent for heart diseases, comprising the mixed cells produced by the method.

6. 发明公开

EP3345610A1 MAPC THERAPEUTICS WITHOUT ADJUNCTIVE IMMUNOSUPPRESSIVE TREATMENT 无效转让
公开(公告)号：EP3345610A1
公开(公告)日：2018-07-11
申请号：EP17200032.5
申请日：2007-01-23
申请人： Athersys, Inc.
发明人： MAYS, Robert W. , DEANS, Robert J.
IPC分类号： A61K35/50 , A61P9/10
CPC分类号： A61K35/50 , A61K31/4353 , A61K31/436 , A61K31/485 , A61K31/52 , A61K31/661 , A61K35/12 , A61K35/28 , A61K35/30 , A61K35/407 , A61K35/44 , A61K35/48 , A61K35/51 , A61K35/545 , A61K38/13 , A61K45/06 , C12N5/0607 , A61K2300/00
摘要： The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like with MAPCs, without the need for adjunctive immunosuppressive treatment.

7. 发明公开

EP3209382A4 COMBINATION IMMUNOTHERAPY APPROACH FOR TREATMENT OF CANCER 有权转让
公开(公告)号：EP3209382A4
公开(公告)日：2018-06-20
申请号：EP15852615
申请日：2015-10-23
申请人： STEMIMMUNE INCORPORATED
发明人： SZALAY ALADAR , MINEV BORIS
IPC分类号： A61P35/00 , A61K35/28 , A61K35/30 , A61K35/44 , A61K35/768 , A61K38/19 , A61K39/395
CPC分类号： A61K39/0011 , A61K9/0019 , A61K31/00 , A61K35/12 , A61K35/28 , A61K35/30 , A61K35/44 , A61K35/51 , A61K35/54 , A61K35/768 , A61K38/19 , A61K38/50 , A61K39/39558 , A61K41/0038 , A61K45/06 , A61K2039/5156 , A61K2039/572 , A61N5/062 , A61N5/10 , A61N2005/0661 , A61N2005/1098 , C07K16/2818 , C07K16/30 , C07K2317/76 , C12Y305/01001
摘要： Disclosed herein are methods and compositions related to combination therapy for cancer. More specifically, several treatment modalities are used in combination to induce an effective anti-tumor immune response. The present invention relates generally to the treatment of human cancer and, more specifically, to use of several treatment modalities in combination to induce effective anti-tumor immune responses.

8. 发明公开

EP3320925A1 CELL STRUCTURE AND METHOD FOR PRODUCING CELL STRUCTURE 有权转让
标题翻译：细胞结构和产生细胞结构的方法
公开(公告)号：EP3320925A1
公开(公告)日：2018-05-16
申请号：EP16824394.7
申请日：2016-07-08
申请人： Fujifilm Corporation
发明人： NAKAMURA Kentaro
IPC分类号： A61L27/00 , A61K35/28 , A61K35/33 , A61K35/34 , A61K35/407 , A61K35/44 , A61P1/16 , A61P1/18 , A61P9/04 , A61P9/10 , A61P13/12 , A61P25/02 , A61P27/02 , C12N5/071
CPC分类号： A61L27/3886 , A61K35/28 , A61K35/33 , A61K35/34 , A61K35/407 , A61K35/44 , A61L27/00 , A61L27/222
摘要： An object of the present invention is to provide a cell structure which can be produced within a short period of time and has a predetermined or larger size, and a method for producing the above-described cell structure. According to the present invention, there is provided a cell structure including: a biocompatible macromolecular block; and two or more kinds of cells, in which a plurality of the biocompatible macromolecular blocks are arranged in gaps between a plurality of the cells, and in which the two or more kinds of cells contain at least one kind of first cell selected from the group consisting of vascular endothelial cells, cardiac muscle cells, pancreatic islet cells, liver cells, epithelial cells, endothelial cells, nerve cells, embryonic stem cells, induced pluripotent stem cells, corneal epithelial cells, and retinal pigment epithelial cells, and at least one kind of second cell selected from the group consisting of mesenchymal cells, stromal cells, fibroblasts, smooth muscle cells, myoblasts, mesenchymal stem cells, adipose-derived stem cells, and umbilical cord-derived stem cells.
摘要翻译：本发明的目的在于提供一种能够在短时间内制造并且具有预定尺寸或更大尺寸的蜂窝结构以及用于制造上述蜂窝结构的方法。根据本发明，提供了一种细胞结构，其包含：生物相容性高分子块; 以及多个所述生物相容性高分子块排列在多个所述细胞间的间隙中的两种以上的细胞，所述两种以上的细胞含有选自所述组中的至少一种第一细胞由血管内皮细胞，心肌细胞，胰岛细胞，肝细胞，上皮细胞，内皮细胞，神经细胞，胚胎干细胞，诱导多能干细胞，角膜上皮细胞和视网膜色素上皮细胞组成，并且至少一种选自间充质细胞，基质细胞，成纤维细胞，平滑肌细胞，成肌细胞，间充质干细胞，脂肪来源的干细胞和来自脐带的干细胞的第二细胞。

9. 发明公开

EP3302452A1 OLIVAMINE-INDUCED IMPROVEMENT IN ENDOTHELIAL CELLS VIABILITY AND FUNCTION 无效
标题翻译： OLAMAMINE诱导的内皮细胞活性和功能改善
公开(公告)号：EP3302452A1
公开(公告)日：2018-04-11
申请号：EP16804536.7
申请日：2016-06-03
申请人： McCord, Darlene E.
发明人： McCord, Darlene E.
IPC分类号： A61K31/05 , A61K31/7048 , C07C39/10
CPC分类号： A61K31/401 , A61K31/05 , A61K31/185 , A61K31/198 , A61K31/7048 , A61K35/44 , A61L26/0057 , A61L26/0066 , A61L2300/412 , A61L2300/64 , A61K2300/00
摘要： Compositions for and methods of improving wound healing are disclosed, including compositions for and methods of treating chronic wounds, and compositions for the inhibition and treatment of necrosis and extended quiescence that result in cellular necrosis instead of normal proliferation. The compositions include hydroxytyrosol, oleuropein, or a combination of hydroxytyrosol and oleuropein with endothelial cells. The invention further encompasses methods involving administration of these compositions.

10. 发明授权

EP2554661B2 Stem cell-derived retinal pigment epithelial cells 有权
标题翻译：干细胞衍生的视网膜色素上皮细胞
公开(公告)号：EP2554661B2
公开(公告)日：2018-02-21
申请号：EP12181140.0
申请日：2008-04-27
申请人： Hadasit Medical Research Services & Development Limited
发明人： Idelson, Masha , Alper-Pinus, Ruslana , Obolensky, Alex , Banin, Eyal , Reubinoff, Benjamin , Hemo, Yitzchak
IPC分类号： C12N5/079 , A61K35/44 , A61K35/48
CPC分类号： A61K35/30 , A61K9/0051 , A61K35/44 , A61K35/48 , C12N5/0621 , C12N5/0696 , C12N2500/38 , C12N2500/90 , C12N2500/99 , C12N2501/115 , C12N2501/15 , C12N2501/155 , C12N2501/16 , C12N2501/999 , C12N2502/13 , C12N2506/02 , C12N2533/52
摘要： A method for promoting directed differentiation of human stem cells (hSCs) into retinal pigment epithelium (RPE) fate, the method comprising: a. providing a cell culture comprising hSCs; b. culturing cells in a culture system comprising a basic medium supplemented with one or more members of transforming growth factor ² (TGF ²) superfamily, whereby said hSCs are induced to differentiate into RPE fate.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式