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1. 发明授权

EP2823712B1 Bone denuder 有权
标题翻译： Knochendenuder
公开(公告)号：EP2823712B1
公开(公告)日：2017-02-15
申请号：EP14184677.4
申请日：2010-12-23
申请人： Medtronic Xomed, Inc.
发明人： Koltz, Michael L. , Shadeck, Louis M. , Oliver, Dana A. , Norman, Gerould W. , Little, David J.
IPC分类号： A22C17/04 , A61F2/46 , A22C17/06 , B02C19/00 , B02C19/11
CPC分类号： A61F2/4644 , A22C17/04 , A22C17/06 , A61F2002/4645 , A61F2002/4646 , B02C19/0056 , B02C19/11

2. 发明公开

EP3005977A1 AUTOMATIC MACHINE FOR PROCESSING TOOTH BY BONE GRAFT MATERIAL 有权
标题翻译：自动化设备ZURHNBEARBEITUNG DURCH KNOCHENTRANSPLANTATMATERIAL
公开(公告)号：EP3005977A1
公开(公告)日：2016-04-13
申请号：EP14808188.8
申请日：2014-06-09
申请人： Korea Dental Solution Co., Ltd
发明人： KIM, Sang Hun , KIM, Gyoo Cheon
IPC分类号： A61C19/00 , A61L27/38 , A61F2/28
CPC分类号： A61F2/4644 , A61C8/0012 , A61C19/00 , A61F2002/4646 , A61F2002/465 , A61F2240/002 , A61L2/0011 , A61L2/0088 , B08B3/04
摘要： An automatic machine for processing a tooth by a graft material includes: a body (10) including a power supply (60) supplying power to a controller, which controls the amount of supply solution and operation of a suction pump (40) and a vibrator (80), and having a receiving space; a receiving container (53) disposed in the receiving space, having a space for keeping a tooth bone graft material, and including a net (59) and a cover (51) having a handle (52); a cylinder (55) having a space for keeping the receiving container (53), and inlets (56) and outlets (57) for supplying and discharging the supply solution; a vibrator (80) fastened to the cylinder (55) and generating vibration of 1 to 100,000 VPM; a supplying container (20) supplying the supply solution to the cylinder (55); and a suction pump (40) discharging solution in the cylinder (55) to a discharging container (70).
摘要翻译：用于通过移植材料处理牙齿的自动机器包括：主体（10），其包括向控制器供电的电源（60），所述电源控制供给液的量和抽吸泵（40）的操作和振动器（80），并具有接收空间; 设置在容纳空间中的容纳容器（53），具有用于保持牙齿骨移植材料的空间，并且包括具有手柄（52）的网（59）和盖（51）; 具有用于保持接收容器（53）的空间的气缸（55）和用于供应和排出供给溶液的入口（56）和出口（57）紧固到所述气缸（55）并产生1至100,000VVM的振动的振动器（80）; 供应容器（20），其将供应溶液供应到气缸（55）; 以及将气缸（55）中的溶液排出到排出容器（70）的抽吸泵（40）。

3. 发明授权

EP2521457B1 SYSTEM AND METHOD OF BONE PROCESSING 有权
标题翻译：系统和方法处理骨
公开(公告)号：EP2521457B1
公开(公告)日：2015-02-25
申请号：EP10798445.2
申请日：2010-12-23
申请人： Medtronic Xomed, Inc.
发明人： KOLTZ, Michael L. , SHADECK, Louis M. , OLIVER, Dana A. , NORMAN, Gerould W. , LITTLE, David J.
IPC分类号： A22C17/06 , A22C17/04 , A61F2/46
CPC分类号： A61F2/4644 , A22C17/04 , A22C17/06 , A61F2002/4645 , A61F2002/4646 , B02C19/0056 , B02C19/11

4. 发明公开

EP2303155A2 ASEPTIC, HIGH PRESSURE WATER CLEANING CHAMBER 审中-公开
标题翻译：无菌高压水清洗室
公开(公告)号：EP2303155A2
公开(公告)日：2011-04-06
申请号：EP09798238.3
申请日：2009-06-23
申请人： Allosource
发明人： KLEIN, Raymond , PARKS, Brent , HOOKS, Alan , FOWLER, Elizabeth
IPC分类号： A61B17/3203 , A61B17/22 , A61B17/50
CPC分类号： A61F2/4644 , A61B17/3203 , A61B90/05 , A61B90/70 , A61B2017/00969 , A61F2002/4646
摘要： There are disclosed systems and methods of debriding tissue. In an embodiment, a system includes a bone tube having an opening sized to receive a bone with tissue disposed thereon, the opening of the bone tube sized to exclude entry of an operator's hand; a spray nozzle configured to emit a water jet into the bone tube; and an outlet from the bone tube. In another embodiment, a method includes assembling a sterile debridement system; placing a sterile mesh bag over a bone tube having an opening sized to receive a bone with tissue disposed thereon, the opening of the bone tube sized to exclude entry of an operator's hand; inserting one end of a bone into the bone tube; actuating a spray nozzle directed into the bone tube, and the water jet configured to debride tissue from the bone within the bone tube. Other embodiments are also disclosed.

5. 发明公开

EP2265220A1 CANCELLOUS CONSTRUCTS, CARTILAGE PARTICLES AND COMBINATIONS OF CANCELLOUS CONSTRUCTS AND CARTILAGE PARTICLES 审中-公开
标题翻译：松构造，软骨颗粒和松构建体和软骨颗粒组合
公开(公告)号：EP2265220A1
公开(公告)日：2010-12-29
申请号：EP09717359.5
申请日：2009-03-05
申请人： Musculoskeletal Transplant Foundation
发明人： TRUNCALE, Katherine, G. , SEMLER, Eric, J. , GERTZMAN, Arthur, A. , SUNWOO, Moon, Hae , TOMFORD, William, W. , SHIKHANOVICH, Roman , CALLAHAN, Alex, B. , YANNARIELLO-BROWN, Judith, I. , HUANG, Yen-chen , JACOBS, Morris, L. , MUNSON, John, C.
IPC分类号： A61F2/28 , A61F2/30
CPC分类号： A61F2/30756 , A61B17/00491 , A61F2/28 , A61F2/3094 , A61F2/3859 , A61F2/3872 , A61F2002/2817 , A61F2002/2839 , A61F2002/2842 , A61F2002/30057 , A61F2002/30059 , A61F2002/30062 , A61F2002/30224 , A61F2002/30225 , A61F2002/30227 , A61F2002/30233 , A61F2002/30235 , A61F2002/30327 , A61F2002/30331 , A61F2002/30354 , A61F2002/30387 , A61F2002/30448 , A61F2002/30459 , A61F2002/30461 , A61F2002/30492 , A61F2002/30604 , A61F2002/30759 , A61F2002/30762 , A61F2002/30764 , A61F2002/30772 , A61F2002/30785 , A61F2002/30789 , A61F2002/30795 , A61F2002/3085 , A61F2002/30932 , A61F2002/3096 , A61F2002/4635 , A61F2002/4646 , A61F2002/4649 , A61F2210/0004 , A61F2220/0025 , A61F2220/0033 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0069 , A61F2250/0039 , A61F2310/00365 , A61L27/3608 , A61L27/3612 , A61L27/3654 , A61L27/48 , A61L27/54 , A61L2300/414 , A61L2300/43 , A61L2430/06 , C08L89/00
摘要： Constructs that are at least partially constructed of allograft cancellous bone are disclosed, along with cartilage particles that may be used with the constructs for repairing articular cartilage defects. A multi-piece construct (20) includes a base member (22), a cap member (30) and at least one pin (40) that secures the cap member (30) to the base member (20). The base member (22) may be constructed of mineralized cancellous bone, and is used to replace the subchondral bone removed when a surgeon cuts a bore in the area of an adjacent cartilage defect. The base member (22) includes a blind bore (23) and first and second through-going transverse bores (28, 29) in opposite sides of a wall of the base member (22). The cap member (30) includes an upper section (32) that has a thickness that is similar to that of a patient's surrounding articular cartilage layer and a stem (36) depending from the upper section (32) that is dimensioned to be received in and by the blind bore (23) of the base member (22). The stem (36) includes a transverse through-going bore (37), which may be aligned with the transverse through-going bores (28, 29) of the base member (22) to receive the pin (40) therein when the construct (20) has been assembled. The cap member (30) is at least partially formed of demineralized allograft cancellous bone, into which a mixture containing lyophilized, freeze-milled allograft cartilage particles may be infused for the repair of articular cartilage defects. The cartilage particles have a size within a range of from about 10 microns to about 210 microns.

6. 发明公开

EP2167148A2 METHOD OF TREATING TISSUE 有权转让
标题翻译： VERFAHREN ZUR BEHANDLUNG VON GEWEBE
公开(公告)号：EP2167148A2
公开(公告)日：2010-03-31
申请号：EP08771193.3
申请日：2008-06-16
申请人： Osteotech, Inc.,
发明人： SHIMP, Lawrence, A. , WEI, Guobao
IPC分类号： A61L27/36 , A61F2/28
CPC分类号： A61L27/3691 , A61F2/4644 , A61F2002/4646 , A61L27/30 , A61L27/34 , A61L27/3604 , A61L27/3847 , A61L27/48 , A61L27/50 , A61L2430/40 , C08L67/04
摘要： In one embodiment, the method comprises providing tissue, preparing the tissue, and treating the tissue to improve remodeling characteristics of the tissue. The tissue may be, for example, cortical bone. Treating the tissue to improve remodeling characteristics may comprise heating the tissue, treating the tissue with a chemical, or other. Heating the tissue may be done in the absence of oxygen and may comprise heating the tissue in a vacuum, heating the tissue in an inert atmosphere, heating the tissue in a reducing atmosphere, coating the tissue with a protective coating and heating the tissue, or other. Further embodiments comprise treating the tissue in supercritical fluids, for example, to dry or virally inactivate the tissue.
摘要翻译：在一个实施方案中，该方法包括提供组织，制备组织和处理组织以改善组织的重塑特征。组织可以是例如皮质骨。处理组织以改善重塑特征可包括加热组织，用化学品或其它物质处理组织。加热组织可以在没有氧的情况下进行，并且可以包括在真空中加热组织，在惰性气氛中加热组织，在还原气氛中加热组织，用保护涂层涂覆组织并加热组织，或其他。另外的实施方案包括处理超临界流体中的组织，例如干燥或病毒灭活组织。

7. 发明公开

EP1700582A2 Osteochondral core centrifugation system 审中-公开
标题翻译：系统zum Zentrifugieren eines osteochondralen Kerns
公开(公告)号：EP1700582A2
公开(公告)日：2006-09-13
申请号：EP06445007.5
申请日：2006-03-08
申请人： Allograft Tissue Systems, Inc.
发明人： Shepard, David O.
IPC分类号： A61F2/46 , A61F2/28 , A61F2/30 , A61F2/38 , A61L27/38
CPC分类号： A61F2/30756 , A61F2/28 , A61F2/3094 , A61F2/3859 , A61F2/4644 , A61F2002/2817 , A61F2002/2839 , A61F2002/30004 , A61F2002/30062 , A61F2002/30224 , A61F2002/30677 , A61F2002/4646 , A61F2002/4649 , A61F2210/0004 , A61F2230/0069 , A61F2250/0014 , A61K35/32 , A61K38/00 , A61L27/3608 , A61L27/3612 , A61L27/3654 , A61L27/3683 , A61L2430/06
摘要： An osteochondral centrifugation system for providing an osteochondral centrifuged core from a graft such as femoral condyle, for example. The centrifugation system may be used either in the operating room or, alternatively, at a tissue banking facility at the time of processing. The osteochondral centrifuged core is formed by (i) removing an osteochondral core from a graft; (ii) placing the osteochondral core in a centrifugation system to remove blood, lipids, or other potentially antigenic or contaminating materials, and to obtain a centrifuged core; and (iii) optionally, subjecting the centrifuged core to a material that reduces the chance of disease transmission and aids in the healing of the recipient site to which the centrifuged core is to be transferred.
摘要翻译：一种用于从例如股骨髁（54）的移植物提供骨软骨离心芯（100）的软骨软骨离心系统（10）。离心系统（10）可以在加工时在手术室中使用，或者在组织银行设备中使用。骨软骨离心芯（100）通过以下步骤形成：（i）从移植物中去除骨软骨; （ii）将骨软骨芯放置在离心系统（10）中以去除血液，脂质或其他潜在的抗原性或污染性材料，并获得离心芯（100）; 和（iii）任选地，将离心的芯（100）经受减少疾病传播机会的材料，并有助于转运离心的芯（100）的受体部位的愈合。

8. 发明公开

EP3417889A1 BIOACTIVE GRAFTS AND COMPOSITES 审中-公开
公开(公告)号：EP3417889A1
公开(公告)日：2018-12-26
申请号：EP18186867.0
申请日：2010-12-03
申请人： Govil, Amit Prakash
发明人： GAMBOA, Christian , GOVIL, Amit Prakash
IPC分类号： A61L27/56 , A61L27/20 , A61L27/12 , A61L27/38 , A61F2/28 , A61L27/46
CPC分类号： A61L27/227 , A61F2/28 , A61F2/4644 , A61F2002/2817 , A61F2002/4646 , A61K35/32 , A61L27/20 , A61L27/3608 , A61L27/365 , A61L27/3687 , A61L27/3691 , A61L27/46 , A61L27/54 , A61L27/56 , A61L2300/414 , A61L2300/64 , A61L2400/16 , A61L2430/02 , A61L2430/40 , C08L5/08
摘要： Disclosed are various bioactive grafts and/or biocompatible materials and methods of making the same. In one embodiment, bone material is harvested from a donor. The harvested bone material is exposed to a lysing agent, the lysing agent configured to release growth factors and bioactive materials from cellular material of the harvested bone material. The harvested bone material is then rinsed with a rinsing agent. The pH of the harvested bone material is substantially neutralized. In another embodiment, an orthopaedic implant includes an antibacterial polysaccharide. The implant may also include an osteostimulative agent.

9. 发明授权

EP2797559B1 BONE CLEANING ASSEMBLY INCLUDING CUTTER 有权
标题翻译：骨清洁组件，包括切刀
公开(公告)号：EP2797559B1
公开(公告)日：2017-07-05
申请号：EP12821004.4
申请日：2012-12-28
申请人： Stryker Corporation
发明人： DIEHL, Eric, K. , LYNCH, Robert, E. , HORTON IV, John Coleman , KEILERS, Cyril, A. , BERNERO, John, P.
IPC分类号： A61F2/46
CPC分类号： A61B17/1635 , A61F2/4644 , A61F2002/4646
摘要： A bone stock cleaning assembly includes a shell having a base and a top located above said base so as to have between said base and said top a void space, a cutter formed with a plurality of cutting edges that is rotatably mounted to in the shell void space, a shaving tube disposed around the cutter, the shaving tube being formed to have at least one shaver edge that is located adjacent said cutting edges of the cutter, and a guide disposed in the shell void space, the guide moveable between a disengaged position and an engaged positon and said guide configured to, when moving from the disengaged position to the engaged position, move bone stock received in the void space towards the cutter. The guide is an arm disposed over the shell base that is mounted to the shell to reciprocate over the base between the disengaged and engaged positions so as to, when moving from the engaged position to the disengaged position, allow reorientation of bone stock located between the cutter and said arm and that has a containment wall that is shaped to, when said arm moves from the disengaged position to the engaged position, direct the bone stock towards the cutter and the at least one shaving edge of the shaving tube and that has a face that, when said arm is in the engaged position, presses the bone stock against the cutting edges of the cutter.
摘要翻译：用于清洁手术过程中使用的骨头的清洁模块。清洁模块包括外壳。外壳定义了一个空间来接收骨头。切割器位于空隙空间内。剃刀管围绕刀具同轴布置以相对于刀具以不同的速度和/或方向移动。当启动时，切割器旋转以通过从骨头骨头切割软组织来清洁骨头。滚筒板重新调整骨头的方向，而手臂穿过滚筒板从脱离位置移动到啮合位置，以通过剃须管中的窗口将骨头压入切割器中。驱动组件驱动切割器，剃须管，臂和翻转板。

10. 发明公开

EP3005977A4 AUTOMATIC MACHINE FOR PROCESSING TOOTH BY BONE GRAFT MATERIAL 有权
标题翻译：自动化机器牙科治疗骨移植材料
公开(公告)号：EP3005977A4
公开(公告)日：2017-03-15
申请号：EP14808188
申请日：2014-06-09
申请人： KOREA DENTAL SOLUTION CO LTD
发明人： KIM SANG HUN , KIM GYOO CHEON
IPC分类号： A61C19/00 , A61F2/28 , A61F2/46 , A61L27/36 , A61L27/38
CPC分类号： A61F2/4644 , A61C8/0012 , A61C19/00 , A61F2002/4646 , A61F2002/465 , A61F2240/002 , A61L2/0011 , A61L2/0088 , B08B3/04
摘要： An automatic machine for processing a tooth by a graft material includes: a body (10) including a power supply (60) supplying power to a controller, which controls the amount of supply solution and operation of a suction pump (40) and a vibrator (80), and having a receiving space; a receiving container (53) disposed in the receiving space, having a space for keeping a tooth bone graft material, and including a net (59) and a cover (51) having a handle (52); a cylinder (55) having a space for keeping the receiving container (53), and inlets (56) and outlets (57) for supplying and discharging the supply solution; a vibrator (80) fastened to the cylinder (55) and generating vibration of 1 to 100,000 VPM; a supplying container (20) supplying the supply solution to the cylinder (55); and a suction pump (40) discharging solution in the cylinder (55) to a discharging container (70).

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