专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP3810034B1 MATRICE DERMIQUE ACELLULAIRE, NOTAMMENT POUR PROTHESE MAMMAIRE 有权
公开(公告)号：EP3810034B1
公开(公告)日：2024-10-16
申请号：EP19737004.2
申请日：2019-06-21
IPC分类号： A61F2/12 , A61L27/36 , A61L27/50 , A61F2/00
CPC分类号： A61F2/0063 , A61F2/0077 , A61F2/12 , A61L27/362 , A61L27/50 , A61L2430/0420130101 , A61L27/3683

2. 发明公开

EP4440638A1 PRODUCTION PROCESS OF A PULVERIZED SCAFFOLD 审中-实审
公开(公告)号：EP4440638A1
公开(公告)日：2024-10-09
申请号：EP22822222.0
申请日：2022-11-29
申请人： Riccio, Michele , Bondioli, Elena
发明人： Riccio, Michele , Bondioli, Elena
IPC分类号： A61L27/36
CPC分类号： A61L27/3604 , A61L27/3691 , A61L27/3683 , A61L2400/1220130101

3. 发明公开

EP3402542A1 NOTOCHORDAL CELL MATRIX AS A STIMULANT FOR INTERVERTEBRAL DISC REGENERATION 有权
公开(公告)号：EP3402542A1
公开(公告)日：2018-11-21
申请号：EP17701425.5
申请日：2017-01-10
申请人： Technische Universiteit Eindhoven
发明人： ITO, Keita , DE VRIES, Stefan Antonius Henricus
IPC分类号： A61L27/36
CPC分类号： A61L27/3604 , A61L27/3658 , A61L27/3683 , A61L27/3691 , A61L2430/38
摘要： A solubilized notochordal cell matrix powder dissolved in a carrier solvent or formed as a gel is provided. The notochordal cell matrix powder originates from lyophilized and treated porcine nucleus pulposus tissue containing notochordal cells. The powder contains less than 20% of porcine nucleid acids, and the powder contains a substantially unchanged amount of porcine protein content compared to the originating porcine nucleus pulposus tissue.The solubilized notochordal cell matrix powder is capable of stimulating native or stem cells to proliferate and produce a significant increase inglycosaminoglycansand type-II collagen matrix. Embodiments of the invention can be used for the disc regenerative treatment of discogenic back and neck pain in an orthopaedic and/or pharmaceutical setting/approach.

4. 发明授权

EP2949349B1 CELL MATRIX MODIFIED TISSUE ENGINEERING NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREOF 有权
公开(公告)号：EP2949349B1
公开(公告)日：2018-10-31
申请号：EP13872797.9
申请日：2013-05-27
申请人： Nantong University
发明人： GU, Xiaosong , DING, Fei , GU, Yun , XUE, Chengbin , YANG, Yumin , WANG, Yongjun , GONG, Leilei
IPC分类号： A61L27/36 , A61F2/04
CPC分类号： A61L27/3675 , A61L27/18 , A61L27/20 , A61L27/227 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3683 , A61L27/3687 , A61L27/3878 , A61L27/3895 , A61L2430/32 , C12N5/0062 , C12N2513/00 , C12N2525/00 , C12N2527/00
摘要： A tissue engineered nerve graft for repairing peripheral nerve injury consists of a nerve conduit and a extracellular matrix (ECM) that is secreted by autologous or allogeneic support cells and obtained by decellularization. A preparation method of the ECM-modified tissue engineered nerve grafts containing support cells, nerve conduit and constructing a ECM-modified tissue engineered nerve graft.

5. 发明公开

EP3383444A1 FILAMENTOUS GRAFT IMPLANTS AND METHODS OF THEIR MANUFACTURE AND USE 有权
公开(公告)号：EP3383444A1
公开(公告)日：2018-10-10
申请号：EP16820050.9
申请日：2016-12-02
申请人： Cook Biotech Incorporated
发明人： BRONIKOWSKI, Christine, M. , OBERMILLER, F., Joseph , COLBURN, Wade, L.
IPC分类号： A61L27/24 , A61L27/36 , A61L31/04
CPC分类号： A61L27/24 , A61L27/3683 , A61L31/044 , A61L2430/36
摘要： A filamentous graft has an elongate filament body including one or more intact segments of a decellularized collagenous tissue membrane. The graft can have a length of at least about 20 cm. The graft can be cut from a laminate of two or more decellularized collagenous tissue membranes. The graft can have a generally rectangular cross-section and can have substantially uniform dimensions and tensile strength along at least a substantial portion of its length. Methods for preparing and using filamentous grafts are also described.

6. 发明授权

EP2241606B1 A METHOD FOR PREPARING A BIOMATERIAL 有权
公开(公告)号：EP2241606B1
公开(公告)日：2018-08-15
申请号：EP08706682.5
申请日：2008-02-15
申请人： Body Organ Biomedical Corp.
发明人： LAI, Horng-Ji , LIN, Chien-Cheng , LIN, Shang-Ming
IPC分类号： A61L27/36
CPC分类号： A61L27/3683 , A61K8/987 , A61L27/3604 , A61L2430/40 , A61Q19/00
摘要： A biomaterial prepared from a process comprising acellularizing the fish scales, dehydrating the fish scales until the fish scales containing less than about 50% of water, and grinding the dehydrated fish scales into ground particles each having an average size of less than about 10,000 µm in diameter, wherein the ground particles contain a mixture of sponge like matrix and powder is provided. The invention also provides a biomaterial prepared from fish scales by a process comprising subjecting the fish scales to a heat treatment at a temperature of less than about 200 °C.

7. 发明公开

EP3331984A1 RAPID ALLOGRAFT TREATMENT SYSTEMS AND METHODS 有权
公开(公告)号：EP3331984A1
公开(公告)日：2018-06-13
申请号：EP16835767.1
申请日：2016-08-08
申请人： AlloSource
发明人： SOUTHARD, Matthew James , SAMANIEGO, Adrian C. , BLOOD, Kenneth , BULL, Marina Katelyn , STILWELL, Reginald , BARRETT, Carolyn , PETERSON, Matthew , ZAJDOWICZ, Jan , JOSLYN, Arthur , HANZLICEK, Kathryn
IPC分类号： C12M1/02
CPC分类号： A61L27/3691 , A61L27/3604 , A61L27/3608 , A61L27/362 , A61L27/3683 , A61L2430/02
摘要： Provided are systems and methods for treating or processing tissue, and tissue products made using such systems and methods. The methods involve combining tissue with a processing solution in a processing vessel and applying resonant acoustic energy thereto. In some instances, the tissue is processed in the absence of processing solution. The resonant acoustic energy rapidly agitates the tissue with the processing solution by vibration. The general method provided is broadly applicable to a variety of tissue processing methods, the processing solution and features of the resonant acoustic energy being selected based on the type of tissue to be processed and the nature of the processing to be performed. Exemplary methods include methods of bone demineralization, tissue decellularization, tissue cryopreservation, production of stromal vascular fraction, tissue homogenization, tissue cleansing, and tissue decontamination, and assessment of microbial load. By applying resonant acoustic energy to the tissue during processing, the rate or efficiency of processing, or both, may be improved.

8. 发明授权

EP2133725B1 Fabrication method for nanofabrication using multi-photon excitation 有权
公开(公告)号：EP2133725B1
公开(公告)日：2018-06-06
申请号：EP09010081.9
申请日：1999-04-21
申请人： University of Connecticut
发明人： Goodman, Steven L. , Campagnola, Paul
IPC分类号： G03F7/20 , G02B21/00
CPC分类号： G03G5/00 , A61K9/0097 , A61K47/6903 , A61K47/6927 , A61L27/3683 , A61L27/50 , A61L2400/12 , A61L2400/18 , B33Y10/00 , B33Y30/00 , C07K14/75 , C07K14/765 , C07K17/04 , C12N11/04 , G01Q80/00 , G02B21/32 , G03F7/0037 , G03F7/029 , G03F7/038 , G03F7/2022 , G03F7/2051 , G03F7/2053
摘要： The invention comprises of an apparatus for fabrication by multi-photon excitation, comprising a photon source in connection with 4pi optics, wherein the 4pi optics comprises a first high NA lens located above a movable stage and a second high NA lens located beneath the movable stage.

9. 发明公开

EP3207948A1 BONE MATRIX COMPOSITIONS AND METHODS 有权
标题翻译：骨基质组合物和方法
公开(公告)号：EP3207948A1
公开(公告)日：2017-08-23
申请号：EP17163186.4
申请日：2008-06-16
申请人： Warsaw Orthopedic, Inc.
发明人： BEHNAM, Keyvan , WEI, Guobao , FORSYTH, Nanette , BOYCE, Todd M. , SHIMP, Lawrence A.
IPC分类号： A61L27/36 , A61L27/38 , A61L27/54
CPC分类号： A61K35/12 , A61F2/28 , A61F2002/30059 , A61F2310/00359 , A61K35/00 , A61K35/32 , A61L27/3604 , A61L27/3608 , A61L27/3683 , A61L27/3695 , A61L27/3834 , A61L27/54 , A61L2430/02 , A61L2430/40
摘要： Osteoinductive compositions and implants having increased biological activities, and methods for their production, are provided. The biological activities that may be increased include, but are not limited to, bone forming; bone healing; osteoinductive activity, osteogenic activity, chondrogenic activity, wound healing activity, neurogenic activity, contraction-inducing activity, mitosisinducing activity, differentiation-inducing activity, chemotactic activity, angiogenic or vasculogenic activity, and exocytosis or endocytosis-inducing activity. In one embodiment, a method for producing an osteoinductive composition comprises providing partially demineralized bone, treating the partially demineralized bone to disrupt the collagen structure of the bone, and optionally providing a tissue-derived extract and adding the tissue-derived extract to the partially demineralized bone. In another embodiment, an implantable osteoinductive and osteoconductive composition comprises partially demineralized bone, wherein the collagen structure of the bone has been disrupted, and, optionally, a tissue-derived extract.
摘要翻译：提供了具有增加的生物活性的骨诱导组合物和植入物及其制备方法。可能增加的生物活性包括但不限于骨形成; 骨愈合; 成骨活性，软骨形成活性，伤口愈合活性，神经原性活性，收缩诱导活性，有丝分裂诱导活性，分化诱导活性，趋化活性，血管生成或血管发生活性以及胞吐或内吞诱导活性。在一个实施方案中，生产骨诱导组合物的方法包括提供部分去矿质骨，处理部分去矿质骨以破坏骨的胶原结构，并任选提供组织来源的提取物并将来自组织的提取物加入部分去矿化的骨。在另一个实施方案中，可植入的骨诱导性和骨传导性组合物包含部分去矿质的骨，其中骨的胶原结构已被破坏，并且任选地包含来自组织的提取物。

10. 发明公开

EP3202429A1 TISSUE SCAFFOLDS 审中-公开
标题翻译：组织支架
公开(公告)号：EP3202429A1
公开(公告)日：2017-08-09
申请号：EP16201265.2
申请日：2009-08-13
申请人： Kci Licensing, Inc.
发明人： Pedrozo, Hugo , Griffey, Edward, S. , Kaufmann, Christopher
IPC分类号： A61L27/36
CPC分类号： A61L27/3683 , A61L27/362 , A61L27/3633 , A61L2430/40
摘要： Tissue scaffolds are described herein. Also described are devices for treating wounds and methods of treating wounds using tissue scaffolds.
摘要翻译：本文描述了组织支架。还描述了用于治疗伤口的装置和使用组织支架治疗伤口的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式