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1. 发明授权

EP2615973B1 FAIL SAFE RADIATION CONCEALMENT MECHANISM 有权
标题翻译：故障安全辐射MASK机制
公开(公告)号：EP2615973B1
公开(公告)日：2016-03-30
申请号：EP11732519.1
申请日：2011-06-09
申请人： Check-Cap Ltd.
发明人： KIMCHY, Yoav , SOMMER, Rafi
IPC分类号： A61B5/07 , A61B1/04 , A61B6/00
CPC分类号： A61B6/4057 , A61B1/00027 , A61B1/041 , A61B5/6861 , A61B6/06 , A61B6/425 , A61B6/548 , A61B2562/162

2. 发明公开

EP2575620A2 METHOD AND APPARATUS FOR DUAL-MODALITY ULTRASONIC AND NUCLEAR EMISSION MAMMOGRAPHY 有权
标题翻译： VERFAHREN UND VORRICHTUNG ZUR DOPPELMODUS-ULTRASCHALL- UND KERNEMISSIONSMAMMOGRAPHIE
公开(公告)号：EP2575620A2
公开(公告)日：2013-04-10
申请号：EP11725287.4
申请日：2011-06-01
申请人： Mayo Foundation for Medical Education and Research
发明人： O'CONNOR, Michael, K.
IPC分类号： A61B6/00 , A61B6/04 , A61B8/08 , G01T1/164 , G21K1/02
CPC分类号： A61B6/502 , A61B6/037 , A61B6/0414 , A61B6/4057 , A61B6/4258 , A61B6/4291 , A61B6/4417 , A61B6/5247 , A61B8/0825 , A61B8/4416 , A61B8/485 , A61B90/11 , G21K1/025
摘要： A molecular breast imaging ("MBI"} configured for combined MBI and ultrasound imaging or MBI-guided biopsy is provided. In one configuration, the MBI portion of the system includes two opposed gamma ray detectors, while in another configuration only one gamma ray detector is provided. In two detector configurations, a compression plate is provided to make contact with and apply light compression to the subject under examination. One of the gamma ray detectors is configured to be moveable with respect to the other detector such that the gamma ray detector can be moved away from the examination region, thereby allowing access to the breast for an ultrasound imaging system or a breast biopsy device.
摘要翻译：提供了一种配置用于组合MBI和超声成像或MBI指导活检的分子乳腺成像（“MBI”）。在一种配置中，系统的MBI部分包括两个相对的γ射线检测器，而在另一个配置中，仅一个伽马射线检测器在两个检测器配置中，提供压缩板以与被检查物体接触并施加光压缩，其中一个伽马射线检测器被配置为相对于另一检测器可移动，使得伽马射线检测器可以远离检查区域移动，从而允许进入用于超声成像系统或乳房活检装置的乳房。

3. 发明公开

EP2240079A1 METHOD AND SYSTEM FOR DETECTING AND GRADING PROSTATE CANCER 审中-公开
标题翻译：方法和系统进行检测和前列腺癌的分类
公开(公告)号：EP2240079A1
公开(公告)日：2010-10-20
申请号：EP09700097.0
申请日：2009-01-01
申请人： Yeda Research And Development Company Ltd.
发明人： BRESKIN, Amos , CHECHIK, Rachel , SHILSTEIN, Sana , CORTESI, Marco
IPC分类号： A61B6/00 , G06T7/00
CPC分类号： A61B6/50 , A61B6/4057 , A61B6/4092 , A61B6/425 , A61B6/4488 , A61B6/485 , G06T7/0012 , G06T2207/10121 , G06T2207/30081
摘要： A method of estimating a grade of a prostate cancer from zinc data associated with the prostate, the zinc data being arranged gridwise in a plurality of picture-elements representing a zinc map of the prostate. The method comprises, clustering the zinc map according to zinc levels associated with the picture-elements, and estimating a cancer grade of at least one tissue region, based, at least in part, on zinc levels associated with a cluster of picture-elements representing the tissue region.

4. 发明授权

EP1017318B1 METHOD OF IMAGING CELL DEATH IN VIVO 失效
标题翻译：方法用于表示体内细胞死亡
公开(公告)号：EP1017318B1
公开(公告)日：2007-12-05
申请号：EP98920065.4
申请日：1998-04-28
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , University of Washington
发明人： BLANKENBERG, Francis, G. , STRAUSS, H., W. , TAIT, Jonathan, F. , KATSIKIS, Peter, D.
IPC分类号： A61B6/00 , A61K38/17 , A61K49/00 , A61K51/00
CPC分类号： A61K51/088 , A61B6/037 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61K51/087
摘要： A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.

5. 发明公开

EP1035801A4 MINIMALLY INVASIVE SURGICAL PROBE FOR TISSUE IDENTIFICATION AND RETRIEVAL AND METHOD OF USE 审中-公开
标题翻译：微创外科器械FOR -ENTFERNUNGSOWIE面料及检测方法
公开(公告)号：EP1035801A4
公开(公告)日：2005-10-26
申请号：EP98957811
申请日：1998-11-12
申请人： CARE WISE MEDICAL PRODUCTS COR
发明人： CARROLL ROBERT G
IPC分类号： A61B6/00 , A61B6/03 , A61B10/00 , A61B10/02 , A61B10/04 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/32 , A61B19/00 , G01T1/161
CPC分类号： A61B10/02 , A61B6/032 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61B6/4423 , A61B10/0266 , A61B10/04 , A61B10/06 , A61B17/22031 , A61B17/32056 , A61B2010/0225 , A61B2017/00079 , A61B2017/320044 , A61B2017/320048 , A61B2090/3908 , A61B2090/392 , G01T1/161
摘要： The present invention is a probe (20) for detecting, and removing radioactively tagged tissue (12), e.g., a sentinel lymph node, within the body of a living being. The probe is arranged to be inserted through a small percutaneous portal into the patient's body, and is movable to various positions adjacent the tagged tissue (12) to detect the presence of radiation therefrom so that the probe can be positioned immediately adjacent that tissue to ensnare or trap it. The probe can then be removed from the patient's body, carrying the tagged tissue with it. The probe may be constructed to make use of a scintillation crystal (52), a collimator, adjustable or fixed, and a back shielding light pipe (64).

6. 发明公开

EP1552789A3 Efficient single photon emission imaging 审中-公开
标题翻译：高效单光子发射成像
公开(公告)号：EP1552789A3
公开(公告)日：2005-07-20
申请号：EP05000202.1
申请日：2005-01-07
申请人： Ultra Spect Ltd.
发明人： Oaknin, Jacob H. , Shwartz, Shoulamit C. , Ohana, Israel
IPC分类号： A61B6/00 , G01T1/164
CPC分类号： G06T11/006 , A61B6/037 , A61B6/4057 , A61B6/503 , A61B6/541 , A61B6/583 , G01T1/1644 , G06T2211/424
摘要： The invention relates to efficient single photon emission imaging. A method of shortening acquisition time for obtaining a reconstructed image of a portion (4) of a body (5) of a human patient who was administered with dosage of radiopharmaceutical substance radiating gamma rays, using SPECT (single photon emission computerized tomography), for determination of functional information thereon, comprises the steps of: (a) acquiring photons (3) emitted from said portion (4) of the body (5), by means of a detector (2) capable of converting the photons (3) into electric signals, the electric signals relating to minimal information required for obtaining a meaningful image; (b) processing said electric signals by a position logic circuitry (7) and thereby deriving therefrom data indicative of positions on said photon detector crystal (6), where the photons have impinged the detector (2); and reconstructing an image of a spatial distribution of the pharmaceutical substance within the portion of the body (5) by iteratively processing said data.

7. 发明公开

EP1552789A2 Efficient single photon emission imaging 审中-公开
标题翻译： Effiziente Einzelphotonemissionsbildgebung
公开(公告)号：EP1552789A2
公开(公告)日：2005-07-13
申请号：EP05000202.1
申请日：2005-01-07
申请人： Ultra Spect Ltd.
发明人： Oaknin, Jacob H. , Shwartz, Shoulamit C. , Ohana, Israel
IPC分类号： A61B6/00 , G01T1/164
CPC分类号： G06T11/006 , A61B6/037 , A61B6/4057 , A61B6/503 , A61B6/541 , A61B6/583 , G01T1/1644 , G06T2211/424
摘要： The invention relates to efficient single photon emission imaging. A method of shortening acquisition time for obtaining a reconstructed image of a portion (4) of a body (5) of a human patient who was administered with dosage of radiopharmaceutical substance radiating gamma rays, using SPECT (single photon emission computerized tomography), for determination of functional information thereon, comprises the steps of:

(a) acquiring photons (3) emitted from said portion (4) of the body (5), by means of a detector (2) capable of converting the photons (3) into electric signals, the electric signals relating to minimal information required for obtaining a meaningful image;
(b) processing said electric signals by a position logic circuitry (7) and thereby deriving therefrom data indicative of positions on said photon detector crystal (6), where the photons have impinged the detector (2); and
reconstructing an image of a spatial distribution of the pharmaceutical substance within the portion of the body (5) by iteratively processing said data.
摘要翻译：本发明涉及有效的单光子发射成像。一种缩短采集时间的方法，用于获得使用SPECT（单光子发射计算机断层摄影）照射伽马射线的放射性药物物质的剂量的人类患者的身体（5）的部分（4）的重建图像，确定其上的功能信息包括以下步骤：（a）通过能够将光子（3）转换成光子（3）的检测器（2）获取从所述主体（5）的所述部分（4）发射的光子（3）电信号，与获得有意义的图像所需的最小信息有关的电信号; （b）通过位置逻辑电路（7）处理所述电信号，从而由其导出指示所述光子检测器晶体（6）上的位置的数据，其中光子已经撞击了检测器（2）; 以及通过迭代地处理所述数据来重建所述体内（5）部分内的所述药物物质的空间分布的图像。

8. 发明公开

EP1035801A1 MINIMALLY INVASIVE SURGICAL PROBE FOR TISSUE IDENTIFICATION AND RETRIEVAL AND METHOD OF USE 审中-公开
标题翻译：微创外科器械FOR -ENTFERNUNGSOWIE面料及检测方法
公开(公告)号：EP1035801A1
公开(公告)日：2000-09-20
申请号：EP98957811.7
申请日：1998-11-12
申请人： Care Wise Medical Products Corporation
发明人： CARROLL, Robert, G.
IPC分类号： A61B6/00
CPC分类号： A61B10/02 , A61B6/032 , A61B6/4057 , A61B6/425 , A61B6/4258 , A61B6/4423 , A61B10/0266 , A61B10/04 , A61B10/06 , A61B17/22031 , A61B17/32056 , A61B2010/0225 , A61B2017/00079 , A61B2017/320044 , A61B2017/320048 , A61B2090/3908 , A61B2090/392 , G01T1/161
摘要： The present invention is a probe (20) for detecting, and removing radioactively tagged tissue (12), e.g., a sentinel lymph node, within the body of a living being. The probe is arranged to be inserted through a small percutaneous portal into the patient's body, and is movable to various positions adjacent the tagged tissue (12) to detect the presence of radiation therefrom so that the probe can be positioned immediately adjacent that tissue to ensnare or trap it. The probe can then be removed from the patient's body, carrying the tagged tissue with it. The probe may be constructed to make use of a scintillation crystal (52), a collimator, adjustable or fixed, and a back shielding light pipe (64).

9. 发明公开

EP1007154A2 INTERVENTIONAL PHOTONIC ENERGY EMITTER SYSTEM 失效
标题翻译：医疗干预系统，用于发射光子能
公开(公告)号：EP1007154A2
公开(公告)日：2000-06-14
申请号：EP97947421.0
申请日：1997-11-07
申请人： Boston Scientific Corporation
发明人： CROWLEY, Robert, J.
IPC分类号： A61N5/06
CPC分类号： A61B5/6848 , A61B5/0059 , A61B6/4057 , A61B18/00 , A61B18/18 , A61B18/24 , A61B2017/22021 , A61B2018/1807 , A61N5/0601 , A61N5/062 , A61N2005/0661
摘要： A miniature light device delivers high energy modular photonic energy to an internal tissue region for diagnostic and/or therapeutic purposes. The miniature light device is a light source that can be placed at or near a distal end of an interventional device, providing localized application of energy in an efficient and cost effective manner.

10. 发明授权

EP3946063B1 METHOD OF USING TEMPORAL MEASUREMENTS OF LOCALIZED RADIATION TO ESTIMATE THE MAGNITUDE, LOCATION, AND VOLUME OF RADIOACTIVE MATERIAL IN THE BODY 有权
公开(公告)号：EP3946063B1
公开(公告)日：2024-10-16
申请号：EP20784501.7
申请日：2020-04-02
IPC分类号： A61B6/00 , G01T1/161 , G01T1/164 , A61B6/42 , A61B6/50 , G01T7/00 , A61B6/03
CPC分类号： A61B6/4057 , A61B6/4258 , G01T1/1641 , A61B6/486 , A61B6/504 , A61B6/037 , G01T7/005

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