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1. 发明公开

EP2925228A4 SYRINGE BASED FLUID DIVERSION MECHANISM FOR BODILY-FLUID SAMPLING 有权
标题翻译： FLÜSSIGKEITSUMLEITUNGSMECHANISMUSFÜREINE SPRITZE ZURKÖRPERFLÜSSIGKEITSPROBENAHME
公开(公告)号：EP2925228A4
公开(公告)日：2016-07-06
申请号：EP13859067
申请日：2013-12-02
申请人： MAGNOLIA MEDICAL TECHNOLOGIES INC
发明人： BULLINGTON GREGORY J , PATTON RICHARD G M D , GAW SHAN E
IPC分类号： A61B5/15 , A61B5/153 , A61B5/154 , A61B5/155 , A61B10/00
CPC分类号： A61B5/150251 , A61B5/1405 , A61B5/1416 , A61B5/1427 , A61B5/1438 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150389 , A61B5/150633 , A61B5/150732 , A61B5/153 , A61B5/154 , A61B5/155 , A61B10/0045
摘要： A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
摘要翻译：基于注射器的装置包括壳体，预样品容器和致动器。壳体限定基本上敞开的近端部分和远端部分之间的内部容积，该内部容积包括可连接到管腔限定装置的端口。预样品储存器可流体耦合到端口以接收和分离第一体积的体液。所述致动器至少部分地设置在所述内部容积中，并具有包括接合部分和包括密封构件的远端部分的近端部分。接合部分被配置为允许使用者选择性地将致动器移动到第一配置之间，使得身体流体可以从端口流到预样品容器，以及第二配置，使得体液可以从端口流到样品储存器至少部分地由密封构件和壳体限定。

2. 发明公开

EP2077115A4 PLATELET-RICH PLASMA SEPARATOR AND PLATELET-RICH PLASMA SEPARATION METHOD 有权
标题翻译：分离器，用于对于富血小板血浆分离和富血小板血浆PROCEDURE
公开(公告)号：EP2077115A4
公开(公告)日：2013-12-25
申请号：EP07830193
申请日：2007-10-19
申请人： NIPRO CORP
发明人： MORIMOTO SHINJI , SASAYAMA NORIHISA , SHIRASU AKIO
IPC分类号： A61K35/14 , A61B5/15 , A61M1/02 , G01N1/28 , G01N33/48
CPC分类号： A61M1/029 , A61B5/1416 , A61B5/15003 , A61B5/150236 , A61B5/150244 , A61B5/150335 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/1535 , A61K35/16 , A61M5/31511 , A61M2005/3104 , A61M2005/3106 , A61M2005/31598 , A61M2202/0427
摘要： This invention provides a platelet-rich plasma separator, which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments, and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe (10) and a second syringe (11). The first syringe (10) comprises a first syringe cylinder (13) provided with a first port (12) on which a blood collection needle can be mounted, a first cap (14) detachable from the first port (12), a first gasket (15) for sealing the first syringe cylinder (13) fluid-tightly, which first gasket (15) is reciprocated within the first syringe cylinder (13), and a first plunger (16) provided detachably on the first gasket (15). The second syringe (11) comprises a first hollow needle (30), which can be passed through the first gasket (15), a second syringe cylinder (32) having a second port (31) on which the first hollow needle (30) can be mounted, a second cap (33) detachable from the second port (32), a second gasket (34) for sealing the second syringe cylinder (32) liquid-tightly, which second gasket (34) is reciprocated within the second syringe cylinder (32), and a second plunger (35) provided detachably on the second gasket (34).

3. 发明授权

EP2366418B1 Medical device including an air evacuation system 有权转让
标题翻译：医疗设备，包括空气疏散系统
公开(公告)号：EP2366418B1
公开(公告)日：2017-12-27
申请号：EP11158108.8
申请日：2011-03-14
申请人： Becton, Dickinson and Company
发明人： Lum, Chee Leong , Douglas, Peter , Abid, Waheed
IPC分类号： A61M5/36 , A61M5/315 , A61B5/15 , A61M5/31 , A61M5/178 , A61M5/38 , B65B3/00 , B65B3/12 , A61B5/153 , A61M5/00 , A61B5/00
CPC分类号： A61M5/31513 , A61B5/1411 , A61B5/1416 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150251 , A61B5/150259 , A61B5/150404 , A61B5/15048 , A61B5/150519 , A61B5/150755 , A61B5/153 , A61M5/1782 , A61M5/3145 , A61M5/31511 , A61M5/36 , A61M5/38 , A61M2005/3101 , A61M2005/3112 , A61M2005/3114 , A61M2005/3123 , A61M2005/31516 , B65B3/003 , B65B3/12
摘要： Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel (310), plunger rod (340) and stopper assembly (360) having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel (310), plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere.

4. 发明公开

EP2925228A1 SYRINGE BASED FLUID DIVERSION MECHANISM FOR BODILY-FLUID SAMPLING 有权
标题翻译：液流转向机理飞溅体液采样
公开(公告)号：EP2925228A1
公开(公告)日：2015-10-07
申请号：EP13859067.4
申请日：2013-12-02
申请人： Magnolia Medical Technologies, Inc.
发明人： BULLINGTON, Gregory J. , PATTON, Richard G., M.D. , GAW, Shan E.
IPC分类号： A61B5/15
CPC分类号： A61B5/150251 , A61B5/1405 , A61B5/1416 , A61B5/1427 , A61B5/1438 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150389 , A61B5/150633 , A61B5/150732 , A61B5/153 , A61B5/154 , A61B5/155 , A61B10/0045
摘要： A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

5. 发明公开

EP2366418A2 Medical device including an air evacuation system 有权转让
标题翻译：用的排气系统的医疗装置
公开(公告)号：EP2366418A2
公开(公告)日：2011-09-21
申请号：EP11158108.8
申请日：2011-03-14
申请人： Becton, Dickinson and Company
发明人： Lum, Chee Leong , Douglas, Peter , Abid, Waheed
IPC分类号： A61M5/36 , A61M5/315 , A61M5/00
CPC分类号： A61M5/31513 , A61B5/1411 , A61B5/1416 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150251 , A61B5/150259 , A61B5/150404 , A61B5/15048 , A61B5/150519 , A61B5/150755 , A61B5/153 , A61M5/1782 , A61M5/3145 , A61M5/31511 , A61M5/36 , A61M5/38 , A61M2005/3101 , A61M2005/3112 , A61M2005/3114 , A61M2005/3123 , A61M2005/31516 , B65B3/003 , B65B3/12
摘要： Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary Medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.

6. 发明授权

EP2925228B1 SYRINGE BASED FLUID DIVERSION MECHANISM FOR BODILY-FLUID SAMPLING 有权
公开(公告)号：EP2925228B1
公开(公告)日：2018-09-26
申请号：EP13859067.4
申请日：2013-12-02
申请人： Magnolia Medical Technologies, Inc.
发明人： BULLINGTON, Gregory J. , PATTON, Richard G., M.D. , GAW, Shan E.
IPC分类号： A61B5/15 , A61B10/00 , A61B5/155 , A61B5/153 , A61B5/154
CPC分类号： A61B5/150251 , A61B5/1405 , A61B5/1416 , A61B5/1427 , A61B5/1438 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150389 , A61B5/150633 , A61B5/150732 , A61B5/153 , A61B5/154 , A61B5/155 , A61B10/0045
摘要： A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

7. 发明公开

EP3323452A1 MEDICAL DEVICE INCLUDING AN AIR EVACUATION SYSTEM 有权
公开(公告)号：EP3323452A1
公开(公告)日：2018-05-23
申请号：EP17207405.6
申请日：2011-03-14
申请人： Becton, Dickinson and Company
发明人： Lum, Chee Leong , Douglas, Peter , Abid, Waheed
IPC分类号： A61M5/36 , A61M5/315 , A61B5/15 , A61B5/153 , B65B3/00 , A61M5/31 , A61M5/178 , A61M5/38 , B65B3/12 , A61M5/00 , A61B5/00
CPC分类号： A61M5/31513 , A61B5/1411 , A61B5/1416 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150251 , A61B5/150259 , A61B5/150404 , A61B5/15048 , A61B5/150519 , A61B5/150755 , A61B5/153 , A61M5/1782 , A61M5/3145 , A61M5/31511 , A61M5/36 , A61M5/38 , A61M2005/3101 , A61M2005/3112 , A61M2005/3114 , A61M2005/3123 , A61M2005/31516 , B65B3/003 , B65B3/12
摘要： Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel (310), plunger rod (340) and stopper assembly (360) having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel (310), plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere.

8. 发明授权

EP2077115B1 PLATELET-RICH PLASMA SEPARATOR AND PLATELET-RICH PLASMA SEPARATION METHOD 有权
标题翻译：分离器，用于对于富血小板血浆分离和富血小板血浆PROCEDURE
公开(公告)号：EP2077115B1
公开(公告)日：2016-12-14
申请号：EP07830193.4
申请日：2007-10-19
申请人： NIPRO CORPORATION
发明人： MORIMOTO, Shinji , SASAYAMA, Norihisa , SHIRASU, Akio
IPC分类号： A61K35/14 , A61B5/15 , A61M1/02 , G01N1/28 , G01N33/48
CPC分类号： A61M1/029 , A61B5/1416 , A61B5/15003 , A61B5/150236 , A61B5/150244 , A61B5/150335 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/1535 , A61K35/16 , A61M5/31511 , A61M2005/3104 , A61M2005/3106 , A61M2005/31598 , A61M2202/0427

9. 发明公开

EP2366418A3 Medical device including an air evacuation system 有权转让
标题翻译： Medizinische Vorrichtung mit einemEntlüftungssystem
公开(公告)号：EP2366418A3
公开(公告)日：2012-10-03
申请号：EP11158108.8
申请日：2011-03-14
申请人： Becton, Dickinson and Company
发明人： Lum, Chee Leong , Douglas, Peter , Abid, Waheed
IPC分类号： A61M5/36 , A61M5/315 , A61B5/15 , A61M5/00 , A61B5/00
CPC分类号： A61M5/31513 , A61B5/1411 , A61B5/1416 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150251 , A61B5/150259 , A61B5/150404 , A61B5/15048 , A61B5/150519 , A61B5/150755 , A61B5/153 , A61M5/1782 , A61M5/3145 , A61M5/31511 , A61M5/36 , A61M5/38 , A61M2005/3101 , A61M2005/3112 , A61M2005/3114 , A61M2005/3123 , A61M2005/31516 , B65B3/003 , B65B3/12
摘要： Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary Medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.
摘要翻译：描述了能够从注射器排空空气的能够将液体吸入注射器筒或其它医疗装置的医疗装置组件。示例性医疗装置包括注射器筒，柱塞杆和止动器组件，其具有透气且液体不可渗透的多孔部分和用于在塞子或柱塞杆内形成真空的结构。描述了包括注射器筒，柱塞杆和止动器组件的医疗装置，其具有透气和液体不可渗透的多孔部分和用于在塞子和柱塞杆之间的腔室内形成真空的结构，其中柱塞杆包括密封边缘并且是可相对移动的止动器示例性医疗装置可以包括用于允许渗透通过多孔部分的空气逸出到大气的通气口。还提供了用液体吸取注射器筒的方法。

10. 发明公开

EP2077115A1 PLATELET-RICH PLASMA SEPARATOR AND PLATELET-RICH PLASMA SEPARATION METHOD 有权
标题翻译：分离器FÜRTHROMBOZYTENREICHES等离子体分离器FÜRTHROMBOZYTENREICHES PLASMA
公开(公告)号：EP2077115A1
公开(公告)日：2009-07-08
申请号：EP07830193.4
申请日：2007-10-19
申请人： Nipro Corporation
发明人： MORIMOTO, Shinji , SASAYAMA, Norihisa , SHIRASU, Akio
IPC分类号： A61K35/14 , A61B5/15 , A61M1/02 , G01N1/28 , G01N33/48
CPC分类号： A61M1/029 , A61B5/1416 , A61B5/15003 , A61B5/150236 , A61B5/150244 , A61B5/150335 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/1535 , A61K35/16 , A61M5/31511 , A61M2005/3104 , A61M2005/3106 , A61M2005/31598 , A61M2202/0427
摘要： This invention provides a platelet-rich plasma separator, which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments, and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe (10) and a second syringe (11). The first syringe (10) comprises a first syringe cylinder (13) provided with a first port (12) on which a blood collection needle can be mounted, a first cap (14) detachable from the first port (12), a first gasket (15) for sealing the first syringe cylinder (13) fluid-tightly, which first gasket (15) is reciprocated within the first syringe cylinder (13), and a first plunger (16) provided detachably on the first gasket (15). The second syringe (11) comprises a first hollow needle (30), which can be passed through the first gasket (15), a second syringe cylinder (32) having a second port (31) on which the first hollow needle (30) can be mounted, a second cap (33) detachable from the second port (32), a second gasket (34) for sealing the second syringe cylinder (32) liquid-tightly, which second gasket (34) is reciprocated within the second syringe cylinder (32), and a second plunger (35) provided detachably on the second gasket (34).
摘要翻译：本发明提供了一种富含血小板的血浆分离器，其能够利用少量γ射线灭菌器具进行富含血小板的血浆的分离，以及富含血小板的血浆分离方法。富含血小板的血浆分离器包括第一注射器（10）和第二注射器（11）。第一注射器（10）包括设置有第一端口（12）的第一注射器筒（13），可以在其上安装采血针，从第一端口（12）可拆卸的第一帽（14），第一垫圈（15），用于密封所述第一注射器筒（13），所述第一衬垫（15）在所述第一注射器筒（13）内往复运动，以及可拆卸地设置在所述第一衬垫（15）上的第一柱塞（16）。第二注射器（11）包括可以穿过第一衬垫（15）的第一中空针（30），具有第二口（31）的第二注射器筒（32），第一中空针（30）可以安装第二帽（33），其可与第二端口（32）分离;第二垫圈（34），用于液密地密封第二注射器筒（32），该第二垫圈（34）在第二注射器气缸（32）和可拆卸地设置在第二垫圈（34）上的第二柱塞（35）。

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