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1. 发明公开

EP3386580A1 CATHETER WITH A LUMEN SHAPED AS AN IDENTIFICATION SYMBOL 有权
公开(公告)号：EP3386580A1
公开(公告)日：2018-10-17
申请号：EP16820436.0
申请日：2016-12-08
申请人： Medtronic Vascular Inc.
发明人： TUOHY, John , WARD, Sean
IPC分类号： A61M25/01 , A61M25/00 , A61B90/96 , A61B90/00
CPC分类号： A61M25/0023 , A61B90/39 , A61B90/96 , A61B2090/3933 , A61B2090/3966 , A61M25/0009 , A61M25/0108 , A61M31/005 , A61M2205/32 , A61M2205/6072 , A61M2207/00 , B29C59/16 , B29L2031/7543
摘要： A catheter includes a catheter shaft having a shaft wall and a lumen extending longitudinally within the shaft wall. The lumen is bounded in radially outward and radially inward directions. The lumen includes a feed portion and an identification symbol fluidly connected to the feed portion. The lumen is configured to receive a contrast media. The lumen may be formed by a channel formed in an outer surface of a first shaft of the catheter shaft, and a covering disposed around the outer surface of the first shaft to cover the channel.

2. 发明公开

EP3370599A1 SYSTEM FOR FLUORESCENCE AIDED SURGERY 无效转让
公开(公告)号：EP3370599A1
公开(公告)日：2018-09-12
申请号：EP16778003.0
申请日：2016-10-06
申请人： Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts , Ruprecht-Karls-Universität Heidelberg
发明人： MAIER-Hein, Lena , STENAU, Esther , TEBER, Dogu
IPC分类号： A61B5/00 , A61B34/20 , A61B90/00 , A61K49/00 , G06T7/00
CPC分类号： A61B5/0071 , A61B5/7425 , A61B90/30 , A61B90/36 , A61B2090/365 , A61B2090/373 , A61B2090/392 , A61B2090/3933 , A61B2090/3941 , A61B2090/502 , A61B2576/00 , G06F19/00
摘要： Disclosed herein is a system for fluorescence aided surgery. The system comprises a storage medium or a data connection with a storage medium storing a 3D data set (28), in particular a medical image, of a patient (10), wherein information regarding a spatial position of one or more fluorescence markers (12) within the body of said patient (10) is included in or associated with said 3D patient data set, a visualization tool (66, 58; 72) allowing for augmenting a view or an image of said patient's body (10) with information derived from said 3D patient data set (28), and an apparatus (64, 74) for detecting fluorescence from said one or more fluorescence markers (12) provided in said patient's body (10). The system further comprises a computation device adapted to derive a spatial relationship between said visualization tool (66, 72) and the patient's body (10), based at least in part on said detected fluorescence of said one or more markers (12), said information regarding said spatial position of said one or more fluorescence markers (12) within the body (10) of said patient included in or associated with said 3D patient data set (28), and a known spatial relationship between the apparatus (64, 74) for detecting fluorescence and said visualization tool (66, 72).

3. 发明公开

EP3182919A1 TISSUE MARKER FOR MULTIMODALITY RADIOGRAPHIC IMAGING 有权
标题翻译：用于多模式射线成像的组织标记器
公开(公告)号：EP3182919A1
公开(公告)日：2017-06-28
申请号：EP15756323.0
申请日：2015-08-20
申请人： Breast-Med, Inc.
发明人： BOLAN, Patrick J. , GROSS, Mark C. , HALPERN, Daniel A. , NELSON, Michael T.
IPC分类号： A61B34/00 , A61B17/00
CPC分类号： A61B90/39 , A61B19/54 , A61B2017/00004 , A61B2019/5433 , A61B2019/5466 , A61B2019/5495 , A61B2090/3925 , A61B2090/3933 , A61B2090/3954 , A61B2090/3966 , A61B2090/3995
摘要： A radiographic marker containing a sensing medium that initially includes a gas and liquid mixture for producing increased signal intensity in a first imaging modality. The radiographic marker can have a permeable portion allowing the exchange of the gases or liquids of the sensing medium to be changed or exchanged for at least a second fluid in the surrounding tissue to reduce the bubbles or air pockets created by the gas portion of the sensing medium. The change or exchange of gas for the second liquid in the radiographic marker produces a detectable signal intensity of the radiographic marker in a second imaging modality different from the first imaging modality.
摘要翻译：包含传感介质的射线照相标记，所述传感介质最初包括用于在第一成像模式中产生增加的信号强度的气体和液体混合物。射线照相标记可具有可渗透部分，其允许感测介质的气体或液体的交换被改变或交换成周围组织中的至少第二流体，以减少由感测的气体部分产生的气泡或气穴中。用于放射线照相标记中的第二液体的气体的改变或交换以不同于第一成像模态的第二成像模式产生放射照相标记的可检测信号强度。

4. 发明公开

EP3165153A1 SYSTEM FOR FLUORESCENCE AIDED SURGERY 无效
标题翻译：荧光辅助手术系统
公开(公告)号：EP3165153A1
公开(公告)日：2017-05-10
申请号：EP15193169.8
申请日：2015-11-05
申请人： Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts , Ruprecht-Karls-Universität Heidelberg
发明人： Maier-Hein, Lena , Wild, Esther
IPC分类号： A61B5/00 , A61B34/20 , A61B90/00 , A61K49/00 , G06T7/00
CPC分类号： A61B5/0071 , A61B5/7425 , A61B90/30 , A61B90/36 , A61B2090/365 , A61B2090/373 , A61B2090/392 , A61B2090/3933 , A61B2090/3941 , A61B2090/502 , A61B2576/00 , G06F19/00
摘要： Disclosed herein is a system for fluorescence aided surgery. The system comprises a storage medium or a data connection with a storage medium storing a 3D data set (28), in particular a medical image, of a patient (10), wherein information regarding a spatial position of one or more fluorescence markers (12) within the body of said patient (10) is included in or associated with said 3D patient data set, a visualization tool (66, 58; 72) allowing for augmenting a view or an image of said patient's body (10) with information derived from said 3D patient data set (28), and an apparatus (64, 74) for detecting fluorescence from said one or more fluorescence markers (12) provided in said patient's body (10). The system further comprises a computation device adapted to derive a spatial relationship between said visualization tool (66, 72) and the patient's body (10), based at least in part on said detected fluorescence of said one or more markers (12), said information regarding said spatial position of said one or more fluorescence markers (12) within the body (10) of said patient included in or associated with said 3D patient data set (28), and a known spatial relationship between the apparatus (64, 74) for detecting fluorescence and said visualization tool (66, 72).
摘要翻译：本文公开了用于荧光辅助手术的系统。该系统包括存储介质或与存储患者（10）的3D数据集（28），特别是医学图像的存储介质的数据连接，其中关于一个或多个荧光标记（12）的空间位置的信息）包括在所述3D患者数据集中或与所述3D患者数据集相关联;可视化工具（66,58; 72），其允许利用导出的信息来增强所述患者身体（10）的视图或图像来自所述3D患者数据集（28）的装置（64,74）以及用于检测来自所述患者身体（10）中提供的所述一个或多个荧光标记物（12）的荧光的装置（64,74）。该系统还包括计算装置，其适于至少部分地基于所述检测到的所述一个或多个标记（12）的荧光，导出所述可视化工具（66,72）与患者身体（10）之间的空间关系，所述关于被包括在所述3D患者数据集（28）中或与所述3D患者数据集（28）相关联的所述患者的身体（10）内的所述一个或多个荧光标记（12）的所述空间位置的信息以及所述设备（64,74 ）用于检测荧光和所述可视化工具（66,72）。

5. 发明公开

EP3129077A1 TAGGED SURGICAL INSTRUMENTS AND METHODS THEREFOR 审中-公开
标题翻译： MARKIERTE CHIRURGISCHE INSTRUMENTE UND VERFAHRENDAFÜR
公开(公告)号：EP3129077A1
公开(公告)日：2017-02-15
申请号：EP15776698.1
申请日：2015-04-10
申请人： Covidien LP
发明人： BLAIR, William A.
IPC分类号： A61L31/00 , A61L31/04
CPC分类号： A61B90/39 , A61B8/481 , A61B17/06004 , A61B90/90 , A61B2017/00526 , A61B2090/3929 , A61B2090/3933 , A61B2090/3983 , A61L17/04 , A61L17/14 , A61L2300/10 , A61L2300/44 , C08L25/06
摘要： Provided herein is a tag comprising an imaging sphere suspended within a matrix. In some embodiments, the matrix comprises a polymer. In some embodiments, the matrix comprises an adhesive polymer. In some embodiments, the matrix comprises a shelf-stable polymer. In some embodiments, the matrix comprises an epoxy. In some embodiments, the adhesive polymer comprises cyanoacrylate. In some embodiments, the imaging sphere comprises a cavity loaded with an imaging agent surrounded by a shell. In some embodiments, the imaging agent exhibits echogenic properties. Further provided is a method for preparing an imaging sphere comprising: depositing organic or inorganic material onto a bead surface to form a sphere with a solid core; removing the solid core by solvent extraction or calcination to form a hollow sphere; and loading the hollow sphere with an imaging agent.
摘要翻译：本文提供的是包括悬挂在矩阵内的成像球的标签。在一些实施方案中，基质包含聚合物。在一些实施方案中，基质包含粘合剂聚合物。在一些实施方案中，基质包含储存稳定的聚合物。在一些实施方案中，基质包含环氧树脂。在一些实施方案中，粘合剂聚合物包含氰基丙烯酸酯。在一些实施例中，成像球包括加载有由壳包围的成像剂的空腔。在一些实施方案中，成像剂显示回声特性。还提供了一种用于制备成像球的方法，包括：将有机或无机材料沉积到珠粒表面上以形成具有实芯的球体; 通过溶剂萃取或煅烧去除固体核心以形成中空球体; 并用成像剂装载中空球体。

6. 发明授权

EP1561420B1 Lesion identification system for surgical operation 有权
标题翻译：系统在手术过程中损伤的鉴定
公开(公告)号：EP1561420B1
公开(公告)日：2017-01-25
申请号：EP05002421.5
申请日：2005-02-04
申请人： Olympus Corporation
发明人： Kaji, Kunihide , Hatta, Shinji , Suzuki, Keita , Morizane, Yuichi , Takara, Toshiyuki , Saito, Tatsuya , Takigawa, Takeshi
IPC分类号： A61B1/06 , A61B5/06 , A61B90/00
CPC分类号： A61B19/54 , A61B5/06 , A61B90/30 , A61B90/39 , A61B2090/3908 , A61B2090/3933 , A61B2090/3941 , A61B2090/3945 , A61B2090/395

7. 发明授权

EP2699183B9 ADAPTABLE DEVICE FOR ELECTRICALLY ISOLATING PULMONARY VEINS IN ATRIAL FIBRILLATION 有权
标题翻译：可调器件肺静脉房颤电隔离
公开(公告)号：EP2699183B9
公开(公告)日：2016-04-20
申请号：EP12713989.7
申请日：2012-04-12
申请人： Atricath S.r.l.
发明人： DASTOLI, Giuseppe , CHIERCHIA, Gian Battista , PERFLER, Enrico
IPC分类号： A61B18/14
CPC分类号： A61B17/3203 , A61B18/02 , A61B18/04 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B2018/00214 , A61B2018/00375 , A61B2018/0212 , A61B2018/1861 , A61B2090/3933 , A61B2090/3966 , A61N7/022

8. 发明授权

EP2275029B1 Lesion identification marker for surgical operation 有权
标题翻译：设备在手术过程中损伤的鉴定
公开(公告)号：EP2275029B1
公开(公告)日：2015-05-20
申请号：EP10013003.8
申请日：2005-02-04
申请人： OLYMPUS CORPORATION
发明人： Kaji, Kunihide , Hatta, Shinji , Suzuki, Keita , Morizane, Yuichi , Takara, Toshiyuki , Saito, Tatsuya , Takigawa, Takeshi
IPC分类号： A61B5/06 , A61B1/06 , A61B19/00
CPC分类号： A61B19/54 , A61B5/06 , A61B90/30 , A61B90/39 , A61B2090/3908 , A61B2090/3933 , A61B2090/3941 , A61B2090/3945 , A61B2090/395

9. 发明公开

EP2809256A2 MULTIMODAL FIDUCIAL MARKER AND MARKER ARRANGEMENT 有权
标题翻译： MULTIMODALER BEZUGSMARKER UND MARKERANORDNUNG
公开(公告)号：EP2809256A2
公开(公告)日：2014-12-10
申请号：EP13709543.6
申请日：2013-01-22
申请人： Koninklijke Philips N.V. , Philips Deutschland GmbH
发明人： RAHMER, Jürgen Erwin , GLEICH, Bernhard , BORGERT, Jörn , KUHN, Michael Harald
IPC分类号： A61B19/00
CPC分类号： A61B90/39 , A61B5/0071 , A61B5/0515 , A61B2090/3933 , A61B2090/3941 , A61B2090/3954 , A61B2090/3995 , A61B2576/00
摘要： A multimodal fiducial marker for registration of multimodal data, including a first portion comprising magnetic material visible in magnetic particle imaging (MPI) data obtained by a magnetic particle imaging method and a second portion comprising a second material visible in image data obtained by another imaging method, which image data is registrable with the MPI data and a corresponding marker arrangement.
摘要翻译：本发明涉及一种用于多模态数据登记的多模态基准标记（10），包括：第一部分（12），包括通过磁性粒子成像方法获得的MPI数据中可见的磁性材料和包括第二材料的第二部分（14）在通过另一成像方法获得的图像数据中可见，哪个图像数据应该与所述MPI数据一起登记。此外，本发明涉及一种标记装置（20）。

10. 发明公开

EP2575623A1 ULTRASONIC VISUALIZATION OF PERCUTANEOUS NEEDLES, INTRAVASCULAR CATHETERS AND OTHER INVASIVE DEVICES 有权转让
标题翻译：超声PICTURE经皮针，导管等侵入血管内器件
公开(公告)号：EP2575623A1
公开(公告)日：2013-04-10
申请号：EP10778725.1
申请日：2010-09-29
申请人： Koninklijke Philips Electronics N.V.
发明人： FERNANDEZ, Anna, Teresa , XIE, Hua , HALL, Christopher, Stephen , GAUTHIER, Thomas , SOKKA, Shunmugavelu
IPC分类号： A61B8/00 , A61B8/08
CPC分类号： A61B8/0833 , A61B8/0841 , A61B8/463 , A61B8/481 , A61B8/483 , A61B18/1477 , A61B2017/3413 , A61B2018/1425 , A61B2090/3925 , A61B2090/3933
摘要： An invasive medical device includes a fluid path of microbubbles which is imaged by ultrasound during use of the device. The fluid path extends through the device, preferably to the distal end of the device, so that the diffuse reflection of ultrasound from the microbubbles can be received to image the location of the device. The fluid path can be open, terminating at the tip of the device, or can be a closed path of a circulating microbubble fluid used for imaging and/or cooling.

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