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    • 4. 发明公开
    • An interventional medical closure device
    • Medizinische Interventionalverschlussvorrichtung
    • EP2260770A2
    • 2010-12-15
    • EP10011576.5
    • 2006-04-28
    • Zerusa Limited
    • Brett, GerardRonan, DavidMulloy, LiamHoran, Steven
    • A61B17/00
    • A61B17/32053A61B17/0057A61B17/0401A61B17/0467A61B2017/00004A61B2017/00336A61B2017/00349A61B2017/00637A61B2017/00654A61B2017/00659A61B2017/0406A61B2017/0458A61B2017/0464A61B2017/22038A61B2017/22048
    • An interventional medical closure device (300) is suitable for assisting closure of an opening through a blood vessel wall after completion of an interventional procedure within the internal lumen of the blood vessel. The device (300) comprises a closure element, a grasping element (302) for grasping the closure element, and a delivery element (304) for delivering the closure element into the internal lumen of the blood vessel. The closure element comprises a suture, and an engagement foot at a distal end of the suture. The grasping element (302) is inter-engageable with the closure element to grasp the closure element. The delivery element (304) comprises a main body portion, and a distant nose (314). The distal nose (314) defines a reception space for carrying the engagment foot of the closure element. The delivery element (304) also comprises an engagement foot (316) which is movable relative to the main body portion between a low-profile delivery configuration and a protruding engagement configuration.
    • 介入性医疗闭合装置(300)适用于在完成血管内腔内的介入手术之后辅助通过血管壁的开口闭合。 装置(300)包括闭合元件,用于抓住闭合元件的抓握元件(302)和用于将封闭元件输送到血管的内腔中的输送元件(304)。 闭合元件包括缝合线和在缝线的远端处的接合脚。 抓握元件(302)可与闭合元件相互接合以抓握封闭元件。 输送元件(304)包括主体部分和远端鼻(314)。 远端鼻(314)限定了用于承载闭合元件的接合脚的接纳空间。 输送元件(304)还包括接合脚(316),该接合脚可在小轮廓输送构型和突出接合构型之间相对于主体部分移动。
    • 5. 发明公开
    • SYSTEM AND METHOD OF USE FOR REVASCULARIZING STENOTIC BYPASS GRAFTS AND OTHERS BLOOD VESSELS
    • 系统和使用方法来再生血管化旁路移植物和其他血管
    • EP0925035A1
    • 1999-06-30
    • EP97935128.0
    • 1997-07-25
    • KENSEY NASH CORPORATION
    • NASH, John, E.
    • A61B17A61D1A61F2A61M31A61M1A61M29
    • A61B17/320758A61B17/22A61B17/32037A61B2017/22048A61B2017/22067A61B2017/320775A61B2217/005A61B2217/007A61M1/0058A61M1/0084A61M5/14232A61M2025/1095A61M2205/05
    • A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the being's body. The introduction of the infusate liquid may also be used to establish an unbalanced flow adjacent the working head to enable the atherectomy catheter to be steered hydrodynamically. A guide wire having an inflatable balloon on its distal end may be used with the atherectomy catheter to block the flow of debris distally, while enabling distal tissues to be perfused with an oxygenating liquid.
    • 用于打开生物体的闭塞血管(例如冠状动脉旁路移植物)中的管腔的系统和方法。 该系统包括具有工作头的旋切术导管,例如旋转冲击叶轮和碎片提取子系统。 旋切术导管位于导引导管内。 工作头布置成对阻塞的血管中的闭塞性物质进行操作,例如撞击,以打开其中的内腔,从而可以产生一些碎屑。 碎片提取子系统在邻近工作头的第一流速下引入输注液体,并且通过引导导管以第二和更高的流速提取该液体和一些血液以在工作头附近形成差流,由此 碎片在输注液体和血液中被抽出以供收集到体外。 输注液体的引入也可以用于在工作头附近建立不平衡流动,以使得旋切术导管能够被流体动力学地操纵。 在远端具有可膨胀球囊的导丝可以与旋切术导管一起使用,以在远侧阻止碎屑流动,同时使得远侧组织能够用充氧液体灌注。