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1. 发明授权

EP1322191B2 REDUCTION OF NITROSAMINES IN TOBACCO AND TOBACCO PRODUCTS 有权
公开(公告)号：EP1322191B2
公开(公告)日：2018-08-01
申请号：EP01977464.5
申请日：2001-10-03
申请人： Schweitzer-Mauduit International, Inc. , LTR Industries
发明人： BASKEVITCH, Nicolas , LE BEC, Lanig , RAVERDY-LAMBERT, Diane
IPC分类号： A24B15/24 , A24B1/02 , A24B15/28
CPC分类号： A24B15/245 , A24B15/24
摘要： A method for reducing the content of nitrosamines (e.g., N'-Nitrosonornicotine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, N'-Nitrosoanatabine, and N'-Nitrosoanabasine) in tobacco is provided. In one embodiment, the method includes combining tobacco with a solvent (e.g., water and/or other compounds) to form a soluble portion. The soluble portion contains an initial total level of tobacco-specific nitrosamines per gram of the soluble portion. The soluble portion is contacted with a nitrosamine-reducing material such that the resulting weight percentage of the tobacco-specific nitrosamines per gram of said soluble portion is at least about 20% less than the initial total level of the tobacco-specific nitrosamines per gram of the soluble portion.

2. 发明公开

EP3182844A2 METHODS FOR FORMING AEROSOL-GENERATING SUBSTRATES HAVING A REDUCED AMOUNT OF TOBACCO SPECIFIC NITROSAMINES 有权
标题翻译：形成具有减少量的烟草特异性亚硝胺的产生气溶胶的基质的方法
公开(公告)号：EP3182844A2
公开(公告)日：2017-06-28
申请号：EP15753036.1
申请日：2015-08-19
申请人： Philip Morris Products S.A.
发明人： LANG, Gerhard , HUFNAGEL, Jan Carlos
IPC分类号： A24B15/22 , A24B15/24
CPC分类号： A24B15/22 , A24B15/245
摘要： There is provided a method of forming an aerosol-generating substrate, the method including providing a liquid nicotine source containing at least one tobacco-specific nitrosamine; mixing the liquid nicotine source with a solvent and at least one aerosol former to form an aerosol-generating substrate; and irradiating the aerosol-generating substrate with ultraviolet light to reduce an amount of the at least one tobacco-specific nitrosamine. Also provided is a method of forming an aerosol-generating substrate, the method including providing a tobacco slurry containing at least one tobacco-specific nitrosamine; irradiating the tobacco slurry with ultraviolet light to reduce an amount of the at least one tobacco-specific nitrosamine; and drying the tobacco slurry to form an aerosol-generating substrate.
摘要翻译：提供了一种形成气雾产生基质的方法，所述方法包括提供含有至少一种烟草特异性亚硝胺的液体尼古丁源，将所述液体尼古丁源与溶剂和至少一种气雾形成剂混合以形成气雾产生用紫外光照射气雾生成基质以减少至少一种烟草特异性亚硝胺的量。还提供了形成气雾产生基质的方法，所述方法包括提供含有至少一种烟草特异性亚硝胺的烟草浆料，用紫外光照射所述烟草浆料以减少所述至少一种烟草特异性亚硝胺的量，并干燥烟草浆料以形成气雾产生基质。

3. 发明公开

EP3082478A1 METHODS FOR REDUCING MATRIX-BOUND NICOTINE-DERIVED NITROSAMINE KETONE IN TOBACCO PLANT MATERIAL 有权
标题翻译：程序MATRIXGEBUNDENEM NITROSAMINKETON尼古丁在烟草植物材料的减少
公开(公告)号：EP3082478A1
公开(公告)日：2016-10-26
申请号：EP14824834.7
申请日：2014-12-18
申请人： Philip Morris Products S.A.
发明人： LANG, Gerhard , SCHALLER, Jean-Pierre , VUARNOZ, Aline
IPC分类号： A24B15/24 , A24B3/12
CPC分类号： A24B5/06 , A24B3/08 , A24B3/12 , A24B3/14 , A24B7/00 , A24B15/10 , A24B15/12 , A24B15/245
摘要： A method of reducing the amount of matrix-bound NNK in cured tobacco plant material is provided comprising reducing the amount of lignin in the cured tobacco plant material. A further method of reducing the formation of matrix-bound NNK during the curing of tobacco plant material is described comprising reducing the amount of lignin therein prior to curing.

4. 发明公开

EP2935588A2 TOBACCO SPECIFIC NITROSAMINE REDUCTION IN PLANTS 审中-公开
标题翻译：氟苯胺中的氨基磺酸钠
公开(公告)号：EP2935588A2
公开(公告)日：2015-10-28
申请号：EP13817681.3
申请日：2013-12-19
申请人： Philip Morris Products S.A.
发明人： BOVET, Lucien , CAMPANONI, Prisca
IPC分类号： C12N15/29 , C12N15/82 , A01H5/12 , A24B15/10
CPC分类号： C12N15/8243 , A24B3/00 , A24B15/18 , A24B15/245 , C07K14/415 , C12N15/8218
摘要： In one aspect, there is provided a mutant, non-naturally occurring or transgenic plant cell comprising: (i) a polynucleotide comprising, consisting or consisting essentially of a sequence encoding a member of the CLC family of chloride channels and having at least 60% sequence identity to SEQ ID NO:1 or SEQ ID NO:2 or SEQ ID NO:3 or SEQ ID NO:4 or SEQ ID NO:10 or SEQ ID NO:11; (ii) a polypeptide encoded by the polynucleotide set forth in (i); (iii) a polypeptide comprising, consisting or consisting essentially of a sequence encoding a member of the CLC family of chloride channels and having at least 60% sequence identity to SEQ ID NO:5 or SEQ ID NO:6 or SEQ ID NO:7 or SEQ ID NO:12 or SEQ ID NO:13 or SEQ ID NO:14; or (iv) a construct, vector or expression vector comprising the isolated polynucleotide set forth in (i); and wherein the expression or activity of the polynucleotide or the polypeptide is modulated as compared to a control plant and wherein the nitrate levels in the mutant, non-naturally occurring or transgenic plant containing the mutant, non-naturally occurring or transgenic plant cell are modulated as compared to the control plant containing the control plant cell.
摘要翻译：一方面，提供了一种突变的非天然存在的或转基因的植物细胞，其包含：（i）多核苷酸，其包含由编码氯化物通道的CLC家族成员的序列组成或基本上由其组成，并具有至少60％与SEQ ID NO：1或SEQ ID NO：2或SEQ ID NO：3或SEQ ID NO：4或SEQ ID NO：10或SEQ ID NO：11的序列同一性; （ii）由（i）所述的多核苷酸编码的多肽; （iii）多肽，其包含，由或基本上由编码氯化物通道的CLC家族成员的序列组成，或者与SEQ ID NO：5或SEQ ID NO：6或SEQ ID NO：7具有至少60％的序列同一性或SEQ ID NO：12或SEQ ID NO：13或SEQ ID NO：14; 或（iv）包含（i）所述的分离的多核苷酸的构建体，载体或表达载体; 并且其中与对照植物相比，调节多核苷酸或多肽的表达或活性，并且其中含有突变非天然存在或转基因植物细胞的突变非天然存在或转基因植物中的硝酸盐水平被调节与含有对照植物细胞的对照植物相比。

5. 发明公开

EP2827727A1 METHOD FOR TREATING AN EXTRACTED TOBACCO PULP AND TOBACCO PRODUCTS MADE THEREFROM 有权
标题翻译： VERFAHREN ZUR BEHANDLUNG EINER EXTRAHIERTEN TABAKPULPE UND DARAUS HERGESTELLTE TABAKPRODUKTE
公开(公告)号：EP2827727A1
公开(公告)日：2015-01-28
申请号：EP13715073.6
申请日：2013-03-19
申请人： R. J. Reynolds Tobacco Company
发明人： BYRD, Crystal Dawn Hege , PU, Yan , GERARDI, Anthony Richard , RHOADES, JR., Charles Bradford
IPC分类号： A24B13/00 , A24B15/24
CPC分类号： A24B13/00 , A24B15/245 , A24B15/246
摘要： The invention provides a method of producing a tobacco composition for use in a tobacco product, the method including treating a tobacco pulp with supercritical carbon dioxide. The treated tobacco pulp may exhibit a benzo[a]pyrene concentration lower than the initial benzo[a]pyrene concentration and/or a TSNA concentration lower than the initial TSNA concentration. The treated pulp can be introduced into tobacco products including smoking articles, smokeless tobacco products, and aerosol-generating devices configured for non-combustion of plant materials.
摘要翻译：本发明提供一种生产用于烟草制品的烟草组合物的方法，该方法包括用超临界二氧化碳处理烟草纸浆。经处理的烟草纸浆可以表现出比初始苯并[a]芘浓度低和/或TSNA浓度低于初始TSNA浓度的苯并[a]芘浓度。经处理的纸浆可以被引入到烟草制品中，包括吸烟制品，无烟烟草制品和被配置用于植物材料的非燃烧的气溶胶发生装置。

6. 发明公开

EP2818059A1 MANUFACTURING METHOD FOR CHEWING TOBACCO MATERIAL, AND CHEWING TOBACCO MATERIAL 有权
标题翻译：咀嚼烟草材料的制造方法和咀嚼烟草材料
公开(公告)号：EP2818059A1
公开(公告)日：2014-12-31
申请号：EP13752001.1
申请日：2013-02-20
申请人： JAPAN TOBACCO INC.
发明人： YOKOI, Michinori , FURUKOSHI, Masashi
IPC分类号： A24B13/00 , A24B15/32
CPC分类号： A24B15/183 , A24B13/00 , A24B15/245 , A24B15/302
摘要： A method for producing an oral tobacco material, characterized by comprising the steps of: adding an antioxidant to a tobacco raw material consisting of a dry oral tobacco material having a pH of 8 or less; and heating the antioxidant-added tobacco raw material at a temperature of 80°C or higher.
摘要翻译：一种生产口用烟草材料的方法，其特征在于包括以下步骤：向由pH等于或低于8的干口味烟草材料组成的烟草原料中加入抗氧化剂; 并且在80℃或更高的温度下加热添加了抗氧化剂的烟草原料。

7. 发明公开

EP2804683A1 SELECTIVE SEPARATION OF NITROSO-CONTAINING COMPOUNDS 审中-公开
标题翻译：亚硝基化合物选择性分离
公开(公告)号：EP2804683A1
公开(公告)日：2014-11-26
申请号：EP12813082.0
申请日：2012-12-21
申请人： British American Tobacco (Investments) Ltd
发明人： BILLING, Johan Fredrik , SVENSSON STARK, Jan Robert Christian , YILMAZ, Ecevit , KARLSSON, Ola John Ivar
IPC分类号： B01D15/26 , A24B15/24 , B01J20/26
CPC分类号： B01D15/265 , A24B15/245 , B01J20/26 , B01J20/261 , B01J20/265 , B01J20/267 , B01J20/268 , B01J20/28004 , B01J20/28059 , B01J20/28061 , B01J20/28069 , B01J20/28083 , B01J20/3057 , B01J20/3064
摘要： Anon-molecularly imprinted polymer is provided that is capable of adsorbing tobacco-specific nitrosamines, said polymer being of a monomer that has polar functionality and cross-linker which is non-acidic, one of said monomers being hydrophilic, the other being hydrophobic. Beads may be made by suspension polymerizing the monomer and cross-linker in an aqueous medium in the presence of a steric stabilizer and a porogen and separating the polymerized material from the reaction mixture. The beads may be useful, for example, in analysis and separation of nitrosamines from biological fluids and in the treatment and manufacture of tobacco products and tobacco materials.

8. 发明授权

EP2011408B1 TOBACCO SHREDS AND METHOD FOR TREATMENT OF TOBACCO 有权
标题翻译：烟草浆和方法烟草治疗
公开(公告)号：EP2011408B1
公开(公告)日：2013-08-07
申请号：EP07742070.1
申请日：2007-04-20
申请人： Japan Tobacco, Inc.
发明人： YOSHIDA, Shinya c/o JAPAN TOBACCO INC., , UWANO, Yoji c/o JAPAN TOBACCO INC., , MORIYAMA, Takako c/o JAPAN TOBACCO INC.,
IPC分类号： A24B15/28 , A24B15/24
CPC分类号： A24B15/28 , A24B15/245 , A24B15/287

9. 发明授权

EP1504679B1 MICROORGANISM REDUCING THE AMOUNT OF NITROSAMINE AND METHOD OF REDUCING THE AMOUNT OF NITROSAMINE USING THE MICROORGANISM 有权
标题翻译：硝基SAMI QUANTITY异径微生物和方法还原硝基SAMI QUANTITY微生物法
公开(公告)号：EP1504679B1
公开(公告)日：2013-01-23
申请号：EP03723306.1
申请日：2003-05-09
申请人： Japan Tobacco Inc.
发明人： KOGA, Kazuharu, c/o Japan Tobacco Inc. , KATSUYA, Satoshi, c/o Japan Tobacco Inc.
IPC分类号： A24B15/20
CPC分类号： A24B15/245 , A24B15/20 , C12R1/01 , C12R1/39

10. 发明公开

EP2448434A1 SMOKELESS TOBACCO PRODUCT 有权
标题翻译：无烟烟草产品
公开(公告)号：EP2448434A1
公开(公告)日：2012-05-09
申请号：EP10802629.5
申请日：2010-06-29
申请人： Philip Morris Products S.A.
发明人： FUISZ, Richard, C.
IPC分类号： A24B13/00
CPC分类号： A24B15/14 , A24B13/00 , A24B15/245 , A24B15/30
摘要： A melt spun tobacco composition, e.g., in flake or particle form, for oral use in a mammal made by melt spinning comprising tobacco and/or a tobacco extract and at least one material which is solid at room temperature, which melts at or below 500° F., and carries from 1% to 70% of tobacco when processed through melt spinning, and solidifies again in less than 5 seconds after melt spinning.

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