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1. 发明授权

EP3391828B1 GRAPHICAL USER INTERFACE FOR TISSUE BIOPSY SYSTEM 有权转让
公开(公告)号：EP3391828B1
公开(公告)日：2020-01-08
申请号：EP18176960.5
申请日：2005-11-28
申请人： Senorx, Inc.
发明人： Daw, Derek , Louw, Frank R. , Lubock, Paul , Quick, Richard L. , Shabaz, Martin V.
IPC分类号： A61B10/02 , A61B90/10 , A61B90/00 , A61B34/00 , A61B5/00 , A61B5/06

2. 发明公开

EP3391828A1 GRAPHICAL USER INTERFACE FOR TISSUE BIOPSY SYSTEM 有权转让
公开(公告)号：EP3391828A1
公开(公告)日：2018-10-24
申请号：EP18176960.5
申请日：2005-11-28
申请人： Senorx, Inc.
发明人： Daw, Derek , Louw, Frank R. , Lubock, Paul , Quick, Richard L. , Shabaz, Martin V.
IPC分类号： A61B10/02 , A61B90/10 , A61B90/00 , A61B34/00
摘要： A graphical user interface is disclosed for a tissue biopsy system having a tissue cutting member adapted for cutting one or more tissue specimens from tissue at a target site within a patient. The graphical user interface includes a first GUI area representing a first region of the target site from which the tissue cutting member has separated one or more tissue specimens. The graphical user interface further includes a second GUI area, visually distinguishable from the first GUI area, representing a second region from which the tissue cutting member may separate one or more additional tissue specimens from tissue at the target site.

3. 发明授权

EP2263547B1 Graphical user interface for tissue biopsy system 有权转让
公开(公告)号：EP2263547B1
公开(公告)日：2018-06-13
申请号：EP10182084.3
申请日：2005-11-28
申请人： Senorx, Inc.
发明人： Daw, Derek , Louw, Frank R. , Lubock, Paul , Quick, Richard L. , Shabaz, Martin V.
IPC分类号： A61B10/02 , A61B90/00 , A61B34/00
CPC分类号： A61B5/061 , A61B5/742 , A61B10/0266 , A61B10/0275 , A61B90/10 , A61B90/37 , A61B2034/254
摘要： A graphical user interface is disclosed for a tissue biopsy system having a tissue cutting member adapted for cutting one or more tissue specimens from tissue at a target site within a patient. The graphical user interface includes a first GUI area representing a first region of the target site from which the tissue cutting member has separated one or more tissue specimens. The graphical user interface further includes a second GUI area, visually distinguishable from the first GUI area, representing a second region from which the tissue cutting member may separate one or more additional tissue specimens from tissue at the target site.

4. 发明授权

EP2389868B1 Drive component with illuminating element in distal portion thereof 有权
标题翻译： Antriebsvorrichtung mit Beleuchtungseinrichtung an ihrem faren Ende
公开(公告)号：EP2389868B1
公开(公告)日：2015-10-28
申请号：EP11175597.1
申请日：2004-12-20
申请人： Senorx, Inc.
发明人： Shabaz, Martin V. , Quick, Richard L. , Louw, Frank R. , Lubock, Paul , Safabash, Jason H.
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B19/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/32053 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00207 , A61B2017/00473 , A61B2017/2911 , A61B2017/2925 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987

5. 发明公开

EP2886135A1 POROUS BIOABSORBABLE IMPLANT 有权转让
标题翻译： Porösesbioabsorbierbares Implantat
公开(公告)号：EP2886135A1
公开(公告)日：2015-06-24
申请号：EP15150927.0
申请日：2009-09-22
申请人： Senorx, Inc.
发明人： Govil, Amit , Jones, Michael L. , Lubock, Paul
IPC分类号： A61L27/20 , A61L27/50 , A61L27/56 , A61L27/58
摘要： The bioabsorbable implant described has a porous body formed of bioabsorbable materials that have an in vivo life span of at least 2 weeks, preferably at least three weeks and not greater than 20 weeks, preferably no greater than ten weeks. The implant has a scaffolding structure which facilitates tissue in-growth and ultimately tissue replacement of the scaffolding structure. The implant has a radiopaque imaging agent at least at the exterior margins and an orientation plurality of radiopaque elements in the interior of implant. The implant preferably has three radiopaque elements within the interior that form a plane within the implant interior.
摘要翻译：所描述的生物可吸收植入物具有由生物可吸收材料形成的多孔体，其具有至少2周，优选至少3周且不超过20周，优选不超过10周的体内寿命。植入物具有促进组织生长并最终组织替代脚手架结构的脚手架结构。植入物至少在外部边缘处具有不透射线的成像剂，并且在植入物内部具有多个不透射线的元件。植入物优选地在内部内具有三个不透射线的元件，其在植入物内部形成平面。

6. 发明授权

EP1919388B1 TISSUE SITE MARKERS FOR IN VIVO IMAGING 有权
标题翻译：布点标记在体内图像表示
公开(公告)号：EP1919388B1
公开(公告)日：2012-12-26
申请号：EP01987032.8
申请日：2001-11-16
申请人： Senorx, Inc.
发明人： BURBANK, Fred, H. , LUBOCK, Paul , QUICK, Richard, L. , LOUW, Frank , DE SANTIS, Stephen, A.
IPC分类号： A61M37/00 , A61B19/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069

7. 发明公开

EP2486957A2 Tissue irradiation with shielding 审中-公开
标题翻译： Gewebebestrahlung mit Abschirmung
公开(公告)号：EP2486957A2
公开(公告)日：2012-08-15
申请号：EP12166143.3
申请日：2006-11-13
申请人： Senorx, Inc.
发明人： Lubock, Paul , Jones, Michael L. , Louw, Frank R.
IPC分类号： A61N5/10 , A61M36/04
CPC分类号： A61N5/1015 , A61B2017/3419 , A61N2005/1005
摘要： Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.
摘要翻译：公开了用于治疗围绕体腔或其他体内部位的组织的装置和方法，例如在去除组织后，例如，癌症。这种装置包括在装置的远端部分上的处理位置，其中一个或多个辐射屏蔽部件在治疗位置部分地环绕辐射源以控制来自辐射源的辐射。该装置最小化对体腔或其他部位周围的健康组织的辐射损伤，同时照射不被辐射屏蔽部件屏蔽的组织。体现本发明特征的装置可包括密封构件，该密封构件位于靠近治疗位置的装置的轴的位置处，以密封通向体腔的通道。

8. 发明公开

EP2407111A1 Biopsy device with selectable tissue receiving aperture orientation and site illumination 有权
标题翻译： Biopsievorrichtung mitwählbarerAusrichtung derGewebeempfangsöffnungund Beleuchtung
公开(公告)号：EP2407111A1
公开(公告)日：2012-01-18
申请号：EP11184498.1
申请日：2005-07-29
申请人： Senorx, Inc.
发明人： Shabaz, Martin V. , Quick, Richard L. , Louw, Frank R. , Lubock, Paul , Safabash, Jason H.
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured.; The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割通过对组织切割构件的内腔施加真空而通过所述孔被拉入所述装置的内部的组织样本。该装置还具有驱动器部件，探头部件可释放地固定到驱动器部件上; 驱动器具有驱动构件，用于调节管状部分的方位，并因此调节其中的孔，以及一个或多个驱动构件，用于移动管状部分内的组织切割构件，以将组织样本从延伸到管状部分内部的组织切断通过光圈。施加到组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

9. 发明授权

EP1558324B1 VACCUM DEVICE FOR TREATING TISSUS ADJACENT A BODY CAVITY 有权
标题翻译：真空装置用于治疗体腔的布边
公开(公告)号：EP1558324B1
公开(公告)日：2011-06-08
申请号：EP03774946.2
申请日：2003-10-28
申请人： Senorx, Inc.
发明人： LUBOCK, Paul
IPC分类号： A61M25/10 , A61B17/00
CPC分类号： A61N5/1015 , A61B2017/22048 , A61B2017/22051
摘要： Devices and methods are provided for applying vacuum near to devices for delivering treatments to tissue adjacent a body cavity, effective to draw adjacent tissue near to such devices and to enhance treatment of the tissue. Body cavities include natural body cavities and cavities remaining after removal of tissue such as cancerous tissue. A device may include an inner balloon assembly with an inflation conduit. A sheath assembly having a fluid-permeable sheath wall may enclose the inner balloon assembly. Vacuum applied to the space between the sheath and the inner balloon is useful to draw tissue into contact with the device, improving treatment effectiveness. Methods for treating tissue with such devices and systems are also provided. Treatment may include providing radioactive material for radiation treatment, providing chemotherapeutic material for chemotherapy, providing thermal treatment, and combinations thereof. Systems may include devices of the invention and a vacuum source.

10. 发明公开

EP2319449A1 Tissue site markers for in vivo imaging 有权
标题翻译： Gewebestellemarkerfürin vivo Bilddarstellungen
公开(公告)号：EP2319449A1
公开(公告)日：2011-05-11
申请号：EP10182074.4
申请日：2001-11-16
申请人： Senorx, Inc.
发明人： Burbank, Fred H. , Lubock, Paul , Quick, Richard L.
IPC分类号： A61B19/00 , A61M37/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores.; The markers may have a nonuniform surface contour, such as a porous, irregular, frosted, faceted, multi-planar or lobulate surface, to enhance the acoustic signature. The markers have a characteristic form which is recognizable artificial during medical imaging. Typically the markers are deposited through an opening in the tissue created by the use of known surgical techniques or more preferably by a disclosed marker applicator device. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.
摘要翻译：本发明是针对活检部位标记和标记活检部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。本发明的活检部位标记物具有高超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。本发明的活检部位标记物的几个公开实施例具有放置在组织部位中的高的声阻抗对比度，以有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。标记可能具有不均匀的表面轮廓，例如多孔，不规则，磨砂，刻面，多平面或细小的表面，以增强声学特征。标记具有在医学成像期间可识别人造的特征形式。通常，通过使用已知的手术技术产生的组织中的开口沉积标记物，或者更优选通过公开的标记施用装置沉积标记物。可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活检腔的迁移。

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