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4. 发明公开

EP3073912A1 VERFAHREN ZUM MAGNETIC PARTICLE IMAGING MIT UNBESCHRÄNKTEM AXIALEN FIELD OF VIEW 有权
标题翻译： VERFAHREN ZUM磁性颗粒成像麻醉剂UNBESCHRÄNKTEMAXIALEN视野
公开(公告)号：EP3073912A1
公开(公告)日：2016-10-05
申请号：EP13802304.9
申请日：2013-11-29
申请人： Universität zu Lübeck
发明人： BUZUG, Thorsten , KAETHNER, Christian , GRÜTTNER, Mandy , BRINGOUT, Gael , WEBER, Matthias
IPC分类号： A61B5/05
CPC分类号： G01R33/1276 , A61B5/0515 , G01R33/307 , G01R33/38
摘要： The invention relates to a method and an MPIS scanner for tomographic imaging of an object with magnetic particles distributed in the interior of the object, comprising the steps of generating a selection magnetic field with a predetermined magnetic field gradient in at least one field-free point (FFP) in a predetermined scanning plane, generating a time-dependent, periodic excitation magnetic field with a predetermined maximum frequency, repeatedly displacing the at least one FFP along a predetermined closed trajectory with a predetermined repetition time in the scanning plane, moving the object through the scanning plane along a predetermined advance direction with a predetermined advance speed, detecting the change in the magnetization state of the magnetic particles at the points in the object interior through which the at least one FFP passes, reconstructing the local particle concentrations at the points through which the at least one FFP passes in respect of an object coordinate system, interpolating the reconstructed particle concentration to the points in the object interior not passed through by at least one FFP, generating a display of the particle concentration distribution in the object interior, characterized by interpolating the particle concentrations reconstructed at path section end points of path sections along the advance direction to path section intermediate points taking into account the advance speed.
摘要翻译：本发明涉及一种用于对物体进行断层成像的方法和MPIS扫描仪，所述物体具有分布在物体内部的磁性粒子，包括以下步骤：在至少一个无场点中产生具有预定磁场梯度的选择磁场（FFP）在预定扫描平面中，产生具有预定最大频率的时间相关的周期性激励磁场，沿着预定的闭合轨迹重复地移动至少一个FFP，并以扫描平面中的预定重复时间移动物体以预定的提前速度沿着预定的前进方向通过扫描平面，检测在至少一个FFP通过的物体内部的点处磁性颗粒的磁化状态的变化，重建在点处的局部颗粒浓度所述至少一个FFP通过其相对于对象坐标通过将重构的粒子浓度内插到未被至少一个FFP通过的物体内部的点，产生物体内部的粒子浓度分布的显示，其特征在于内插在路径路段部分终点处重建的粒子浓度考虑到提前速度，沿前进方向的路段部分中间点。

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