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1. 发明授权

EP1988170B1 METHOD OF PRODUCING CHEMICAL PRODUCT AND CONTINUOUS FERMENTATION APPARATUS 有权
公开(公告)号：EP1988170B1
公开(公告)日：2019-05-01
申请号：EP07714383.2
申请日：2007-02-16
申请人： TORAY INDUSTRIES, INC.
发明人： SAWAI, Hideki , YAMADA, Katsushige , MIMITSUKA, Takashi , SAWAI, Kenji , YONEHARA, Tetsu , ITO, Yohito , HENMI, Masahiro
IPC分类号： C12P13/04 , C12M1/34 , C12M1/00 , C12P7/06 , C12P7/18 , C12P7/46 , C12P7/50 , C12P7/56 , C12P13/08 , C12P19/30 , C12P13/00
CPC分类号： C12P7/06 , C12M29/04 , C12M29/18 , C12M41/40 , C12M47/10 , C12P7/18 , C12P7/46 , C12P7/50 , C12P7/56 , C12P13/001 , C12P13/005 , C12P13/04 , C12P13/08 , C12P19/30 , Y02E50/17
摘要： The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 µm or more to less than 1 µm is used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost.

2. 发明公开

EP1031372A1 METHOD FOR INHIBITING GROWTH OF BACTERIA OR STERILIZING AROUND SEPARATING MEMBRANE 有权
标题翻译：细菌或灭菌方法生长抑制分离膜区
公开(公告)号：EP1031372A1
公开(公告)日：2000-08-30
申请号：EP99929884.7
申请日：1999-07-16
申请人： TORAY INDUSTRIES, INC.
发明人： KIMURA, Takuhei , NAKAOKI, Yuichiro , ITO, Yohito , FUSAOKA, Yoshinari , MIYOSHI, Toshiro
IPC分类号： B01D65/02 , C02F1/44 , C02F9/00
CPC分类号： B01D65/022 , A61L2/18 , B01D61/025 , B01D61/04 , B01D2311/04 , B01D2321/162 , B01D2311/18 , B01D2311/12
摘要： In the invention, the pipe lines around permselective membranes and the surfaces of permselective membranes are intermittently disinfected by adding an inexpensive acid such as sulfuric acid or the like to pre-treated crude water so as to make the water have a pH of 4 or lower. Accordingly, the invention provides a method of surely disinfecting the permselective membranes in membrane separation systems.
摘要翻译：在本发明中，围绕选择性渗透膜的管线和选择性渗透膜的表面通过向廉价的酸被间歇消毒：如硫酸或类似物预先处理过的粗水，以便使水的pH为4或更低的，因此，本发明提供的可靠的消毒在膜分离系统中的选择性渗透膜的方法。

3. 发明授权

EP2175029B1 LACTIC ACID PRODUCTION METHOD 有权
公开(公告)号：EP2175029B1
公开(公告)日：2020-10-07
申请号：EP08777309.9
申请日：2008-06-18
申请人： Toray Industries, Inc.
发明人： ITO, Masateru , MINEGISHI, Shin-ichi , SHIMIZU, Eri , SAWAI, Kenji , ITO, Yohito , SAWAI, Hideki , YAMADA, Katsushige
IPC分类号： C12P7/56 , B01D61/02 , B01D61/14 , B01D71/56 , C12N15/09

4. 发明公开

EP2175029A1 LACTIC ACID PRODUCTION METHOD 有权
标题翻译：乳酸生产工艺
公开(公告)号：EP2175029A1
公开(公告)日：2010-04-14
申请号：EP08777309.9
申请日：2008-06-18
申请人： Toray Industries, Inc.
发明人： ITO, Masateru , MINEGISHI, Shin-ichi , SHIMIZU, Eri , SAWAI, Kenji , ITO, Yohito , SAWAI, Hideki , YAMADA, Katsushige
IPC分类号： C12P7/56 , B01D61/02 , B01D61/14 , B01D71/56 , C12N15/09
CPC分类号： C12P7/56 , B01D61/027 , B01D71/56 , B01D2311/06 , B01D2311/18 , B01D2311/2669
摘要： Disclosed is a lactic acid production method by separating lactic acid produced in a culture solution by means of the fermentation culture of a microorganism. Specifically disclosed is a lactic acid production method, which comprises: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in the step (A) under a pressure ranging from 1 Pa to the atmospheric pressure (inclusive) at a temperature ranging from 25 to 200 DEG C (inclusive) to collect lactic acid. The method can effectively remove an inorganic salt dissolved in a fermentation culture solution or contained in the fermentation culture solution in the form of a poorly soluble solid material by a simple manipulation, enables to prevent the racemization or oligomerization of lactic acid during the process of producing lactic acid, and therefore can produce lactic acid in a high yield.

5. 发明公开

EP2067520A1 METHOD FOR OPERATING REVERSE OSMOSIS MEMBRANE FILTRATION PLANT, AND REVERSE OSMOSIS MEMBRANE FILTRATION PLANT 有权
标题翻译： VERFAHREN ZUM BETRIEB EINER UMKEHROSMOSEMBRANFILTRATIONSANLAGE UND UMKEHROSMOSEMBRANFILTRATIONSANLAGE
公开(公告)号：EP2067520A1
公开(公告)日：2009-06-10
申请号：EP07807653.6
申请日：2007-09-20
申请人： Toray Industries, Inc.
发明人： ITO, Yohito , KANTANI, Seiko , UEMURA, Tadahiro , KITADE, Tamotsu
IPC分类号： B01D61/12 , B01D65/02 , C02F1/44 , C02F1/50
CPC分类号： B01D61/025 , B01D61/12 , B01D65/08 , B01D65/10 , B01D2311/165 , B01D2321/40 , C02F1/441 , C02F1/50 , C02F2103/08 , C02F2209/36 , Y02A20/131
摘要： An object of the present invention is to provide a method for operating a reverse osmosis membrane filtration plant which enables operations including addition of bactericide, chemical cleaning, pre-treatment, and the like which are carried out for the purpose of preventing biofouling of a reverse osmosis membrane module of a reverse osmosis membrane filtration unit highly reliably, highly sensitively, rationally, rapidly and conveniently in a reverse osmosis membrane filtration plant, and the reverse osmosis membrane filtration plant. For this objection, the present invention provides a method for operating a reverse osmosis membrane filtration plant having a raw water intake unit, a pre-treatment unit, and a reverse osmosis membrane filtration unit having a reverse osmosis membrane module in this order, the method including: disposing a biofilm formation base material under conditions that reverse osmosis membrane supply water and/or reverse osmosis membrane non-permeated water in the reverse osmosis membrane filtration unit are/is flowed at a linear speed equal to a non-permeated water linear speed in the reverse osmosis membrane module of the reverse osmosis membrane filtration unit; evaluating a biofilm amount on the biofilm formation base material at a frequency of from once a day to once in six months; and controlling the method for operating a reverse osmosis membrane filtration plant based on results of the evaluation. Particularly, as the biofilm formation base material, a reverse osmosis membrane used in the reverse osmosis membrane filtration plant is used.
摘要翻译：本发明的目的是提供一种操作反渗透膜过滤装置的方法，该方法能够进行包括添加杀菌剂，化学清洁，预处理等的操作，以防止反向生物污损反渗透膜过滤装置的反渗透膜过滤装置的渗透膜组件高度可靠，高度敏感，合理，快速和方便地进行反渗透膜过滤装置。为此，本发明提供一种反渗透膜过滤装置的操作方法，所述反渗透膜过滤装置具有原水进料单元，预处理单元和具有反渗透膜组件的反渗透膜过滤单元，该方法依次为反渗透膜模块包括：在反渗透膜供给水和/或反渗透膜过滤单元中的反渗透膜不渗透水以等于非渗透水线速度的线速度流动的条件下设置生物膜形成基材在反渗透膜组件的反渗透膜过滤单元中; 以每天一次至六个月一次的频率对生物膜形成基材的生物膜量进行评估; 并根据评估结果控制反渗透膜过滤装置的运行方法。特别地，作为生物膜形成基材，使用在反渗透膜过滤装置中使用的反渗透膜。

6. 发明公开

EP1988170A1 METHOD OF PRODUCING CHEMICAL PRODUCT AND CONTINUOUS FERMENTATION APPARATUS 有权
标题翻译：工艺用于生产连续发酵的化学产品和设备
公开(公告)号：EP1988170A1
公开(公告)日：2008-11-05
申请号：EP07714383.2
申请日：2007-02-16
申请人： TORAY INDUSTRIES, INC.
发明人： SAWAI, Hideki , YAMADA, Katsushige , MIMITSUKA, Takashi , SAWAI, Kenji , YONEHARA, Tetsu , ITO, Yohito , HENMI, Masahiro
IPC分类号： C12P7/56 , C12M1/12 , C12P7/06 , C12P7/18 , C12P7/46 , C12P7/50 , C12P13/00 , C12P13/08 , C12P19/30 , C12N15/09
CPC分类号： C12P7/06 , C12M29/04 , C12M29/18 , C12M41/40 , C12M47/10 , C12P7/18 , C12P7/46 , C12P7/50 , C12P7/56 , C12P13/001 , C12P13/005 , C12P13/04 , C12P13/08 , C12P19/30 , Y02E50/17
摘要： The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 µm or more to less than 1 µm is used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost.

7. 发明授权

EP1988170B8 METHOD OF PRODUCING CHEMICAL PRODUCT AND CONTINUOUS FERMENTATION APPARATUS 有权
公开(公告)号：EP1988170B8
公开(公告)日：2019-07-10
申请号：EP07714383.2
申请日：2007-02-16
申请人： Toray Industries, Inc.
发明人： SAWAI, Hideki , YAMADA, Katsushige , MIMITSUKA, Takashi , SAWAI, Kenji , YONEHARA, Tetsu , ITO, Yohito , HENMI, Masahiro
IPC分类号： C12P13/04 , C12M1/34 , C12M1/00 , C12P7/06 , C12P7/18 , C12P7/46 , C12P7/50 , C12P7/56 , C12P13/08 , C12P19/30 , C12P13/00

8. 发明授权

EP2067520B1 METHOD FOR OPERATING REVERSE OSMOSIS MEMBRANE FILTRATION PLANT, AND REVERSE OSMOSIS MEMBRANE FILTRATION PLANT 有权
标题翻译：用于操作反渗透膜过滤装置和反渗透膜过滤装置
公开(公告)号：EP2067520B1
公开(公告)日：2016-04-13
申请号：EP07807653.6
申请日：2007-09-20
申请人： Toray Industries, Inc.
发明人： ITO, Yohito , KANTANI, Seiko , UEMURA, Tadahiro , KITADE, Tamotsu
IPC分类号： B01D61/12 , B01D65/02 , C02F1/44 , C02F1/50 , B01D65/08
CPC分类号： B01D61/025 , B01D61/12 , B01D65/08 , B01D65/10 , B01D2311/165 , B01D2321/40 , C02F1/441 , C02F1/50 , C02F2103/08 , C02F2209/36 , Y02A20/131
摘要： An object of the present invention is to provide a method for operating a reverse osmosis membrane filtration plant which enables operations including addition of bactericide, chemical cleaning, pre-treatment, and the like which are carried out for the purpose of preventing biofouling of a reverse osmosis membrane module of a reverse osmosis membrane filtration unit highly reliably, highly sensitively, rationally, rapidly and conveniently in a reverse osmosis membrane filtration plant, and the reverse osmosis membrane filtration plant. For this objection, the present invention provides a method for operating a reverse osmosis membrane filtration plant having a raw water intake unit, a pre-treatment unit, and a reverse osmosis membrane filtration unit having a reverse osmosis membrane module in this order, the method including: disposing a biofilm formation base material under conditions that reverse osmosis membrane supply water and/or reverse osmosis membrane non-permeated water in the reverse osmosis membrane filtration unit are/is flowed at a linear speed equal to a non-permeated water linear speed in the reverse osmosis membrane module of the reverse osmosis membrane filtration unit; evaluating a biofilm amount on the biofilm formation base material at a frequency of from once a day to once in six months; and controlling the method for operating a reverse osmosis membrane filtration plant based on results of the evaluation. Particularly, as the biofilm formation base material, a reverse osmosis membrane used in the reverse osmosis membrane filtration plant is used.

9. 发明授权

EP1031372B1 METHOD FOR INHIBITING GROWTH OF BACTERIA OR STERILIZING AROUND SEPARATING MEMBRANE 有权
标题翻译：细菌或灭菌方法生长抑制分离膜区
公开(公告)号：EP1031372B1
公开(公告)日：2008-01-02
申请号：EP99929884.7
申请日：1999-07-16
申请人： TORAY INDUSTRIES, INC.
发明人： KIMURA, Takuhei , NAKAOKI, Yuichiro , ITO, Yohito , FUSAOKA, Yoshinari , MIYOSHI, Toshiro
IPC分类号： B01D65/02 , C02F1/44 , C02F9/00
CPC分类号： B01D65/022 , A61L2/18 , B01D61/025 , B01D61/04 , B01D2311/04 , B01D2321/162 , B01D2311/18 , B01D2311/12
摘要： A method for surely sterilizing a separating membrane in a membrane separation apparatus which comprises adding an inexpensive acid such as sulfuric acid intermittently to a liquid feed after being pretreated in such a manner that the feed has a pH of 4 or less, to thereby intermittently sterilize the membrane and the piping in the vicinity thereof.

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