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1. 发明授权

EP2696787B1 DEVICES FOR HEATING FLUID IN FLUID ENHANCED ABLATION THERAPY 有权
公开(公告)号：EP2696787B1
公开(公告)日：2019-01-16
申请号：EP12771331.1
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G. , KIM, Fredrick, J.
IPC分类号： A61B18/04 , A61B18/14 , A61B18/08 , A61B18/16 , A61B18/00 , A61B17/00

2. 发明公开

EP2696787A1 METHODS AND DEVICES FOR HEATING FLUID IN FLUID ENHANCED ABLATION THERAPY 有权
标题翻译：方法和装置用于加热流体在流体辅助消融治疗
公开(公告)号：EP2696787A1
公开(公告)日：2014-02-19
申请号：EP12771331.1
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G. , KIM, Fredrick, J.
IPC分类号： A61B18/04 , A61B18/08 , A61M37/00 , A61M25/01
CPC分类号： A61B18/04 , A61B18/082 , A61B18/1477 , A61B18/16 , A61B2017/00526 , A61B2018/00029 , A61B2018/00041 , A61B2018/00577 , A61B2018/00642 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/00821 , A61B2018/046 , A61B2018/1425 , A61B2018/162 , F04B17/03 , F04B19/22 , F04B43/04 , F04B49/06 , F04C2270/041 , Y10T29/49016 , Y10T29/49085
摘要： Devices and methods for monitoring the temperature of tissue at various locations in a treatment volume during fluid enhanced ablation therapy are provided. In one embodiment, an ablation device is provided having an elongate body, at least one ablation element, and at least one temperature sensor. The elongate body includes a proximal and distal end, an inner lumen, and at least one outlet port to allow fluid to be delivered to tissue surrounding the elongate body. The at least one ablation element is configured to heat tissue surrounding the at least one ablation element. The at least one temperature sensor can be positioned a distance away from the at least one ablation element and can be effective to output a measured temperature of tissue spaced a distance apart from the at least one ablation element such that the measured temperature indicates whether tissue is being heating to a therapeutic level.

3. 发明公开

EP3932347A1 DEVICES FOR USE OF DEGASSED FLUIDS WITH FLUID ENHANCED ABLATION DEVICES 审中-公开
公开(公告)号：EP3932347A1
公开(公告)日：2022-01-05
申请号：EP21191571.5
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B18/04 , A61B18/08 , A61B18/14 , F04B17/03 , F04B41/02 , F04B43/04 , A61B18/00
摘要： Devices, systems, and methods for degassing fluid prior to applying fluid to a treatment site during ablation therapy are provided. In one embodiment, an ablation system can include an elongate body, an ablation element, a heating assembly, and a fluid source. Fluid in the fluid source can be at least partially degassed prior to being provided as part of the system, or, in some embodiments, a degassing apparatus can be provided that can be configured to degas fluid within the system prior to applying the fluid to the treatment site. The degassing apparatus can include one or more gas- permeable and fluid-impermeable tubes disposed therein, which can allow gas to be removed from fluid passing through the apparatus. Other exemplary devices, systems, and methods are also provided.

4. 发明公开

EP3787716A1 DEVICES AND METHODS FOR SELECTIVELY DEPLOYING CATHETER INSTRUMENTS 审中-公开
公开(公告)号：EP3787716A1
公开(公告)日：2021-03-10
申请号：EP19796516.3
申请日：2019-05-03
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G. , KIM, Fredrick, J. , HOWARD, Michael, T. , DELLY, Erik , EBERL, Gregory, R. , LESICA, Jeffrey, J.
IPC分类号： A61M5/178 , A61M5/32 , A61M25/01

5. 发明授权

EP2884928B1 ABLATION DEVICE WITH MEANS FOR HEATING A FLUID, WITH AN ELECTRODE AND WITH A HANDLE PROVIDED AT AN ANGLE 失效
标题翻译：具有用于加热流体的手段的消融装置，具有电极并且具有在角度上提供的手柄
公开(公告)号：EP2884928B1
公开(公告)日：2017-12-20
申请号：EP13829821.1
申请日：2013-08-07
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B17/3203 , A61B18/00 , A61B18/04 , A61B18/14
CPC分类号： A61B18/04 , A61B90/37 , A61B2018/00577 , A61B2018/00815 , A61B2018/00821 , A61B2018/046
摘要： Low profile devices and methods for delivering fluid enhanced ablation therapy are provided herein. In one embodiment, an ablation device is provided that includes an elongate body having proximal and distal ends, an inner lumen extending therethrough and at least one outlet port formed therein and configured to deliver fluid to surrounding tissue. The device can also include at least one ablation element disposed along a length of the body adjacent to the at least one outlet port and configured to deliver energy to surrounding tissue, as well as at least one heating element disposed within the inner lumen of the elongate body. The device further includes a handle having proximal and distal ends, the distal end of the handle being coupled to the proximal end of the elongate body. Further, a longitudinal axis of the elongate body extends at an angle to a longitudinal axis of the handle.

6. 发明公开

EP2884928A1 LOW PROFILE FLUID ENHANCED ABLATION THERAPY DEVICES AND METHODS 失效
标题翻译：消融用于加热液体，用铅和一个倾斜的配置手柄
公开(公告)号：EP2884928A1
公开(公告)日：2015-06-24
申请号：EP13829821.1
申请日：2013-08-07
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B18/12 , A61B18/14 , A61B17/3203 , A61B6/00 , A61B5/055
CPC分类号： A61B18/04 , A61B90/37 , A61B2018/00577 , A61B2018/00815 , A61B2018/00821 , A61B2018/046
摘要： Low profile devices and methods for delivering fluid enhanced ablation therapy are provided herein. In one embodiment, an ablation device is provided that includes an elongate body having proximal and distal ends, an inner lumen extending therethrough and at least one outlet port formed therein and configured to deliver fluid to surrounding tissue. The device can also include at least one ablation element disposed along a length of the body adjacent to the at least one outlet port and configured to deliver energy to surrounding tissue, as well as at least one heating element disposed within the inner lumen of the elongate body. The device further includes a handle having proximal and distal ends, the distal end of the handle being coupled to the proximal end of the elongate body. Further, a longitudinal axis of the elongate body extends at an angle to a longitudinal axis of the handle.
摘要翻译：中提供了低轮廓的装置和用于将流体输送增强消融治疗的方法。在一个，消融装置的实施方式被提供到细长体确实包括具有近端和远端，在内腔延伸穿过那里和至少一个出口端口形成于其中并且被构造成将流体输送到周围的组织。该装置可因此包括至少一个消融元件沿所述主体的邻近所述至少一个出口端口的长度设置及构造成将能量递送到周围组织中，细长的内腔中设置的至少一个以及加热元件体。该装置包括还具有近端和远端手柄，所述手柄的所述远端联接到所述细长本体的近端。此外，细长体的纵向轴线在角度在手柄延伸到的纵向轴线。

7. 发明公开

EP2696790A1 METHODS AND DEVICES FOR CONTROLLING ABLATION THERAPY 有权
标题翻译：方法和设备控制一消融治疗
公开(公告)号：EP2696790A1
公开(公告)日：2014-02-19
申请号：EP12771876.5
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B18/12 , A61B18/18 , A61M37/00 , A61M25/01
CPC分类号： A61B18/04 , A61B18/082 , A61B18/1477 , A61B18/16 , A61B2017/00526 , A61B2018/00029 , A61B2018/00041 , A61B2018/00577 , A61B2018/00642 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/00821 , A61B2018/046 , A61B2018/1425 , A61B2018/162 , F04B17/03 , F04B19/22 , F04B43/04 , F04B49/06 , F04C2270/041 , Y10T29/49016 , Y10T29/49085
摘要： Devices and methods for monitoring the temperature of tissue at various locations in a treatment volume during fluid enhanced ablation therapy are provided. In one embodiment, an ablation device is provided having an elongate body, at least one ablation element, and at least one temperature sensor. The elongate body includes a proximal and distal end, an inner lumen, and at least one outlet port to allow fluid to be delivered to tissue surrounding the elongate body. The at least one ablation element is configured to heat tissue surrounding the at least one ablation element. The at least one temperature sensor can be positioned a distance away from the at least one ablation element and can be effective to output a measured temperature of tissue spaced a distance apart from the at least one ablation element such that the measured temperature indicates whether tissue is being heating to a therapeutic level.

8. 发明公开

EP2696788A1 METHODS AND DEVICES FOR USE OF DEGASSED FLUIDS WITH FLUID ENHANCED ABLATION DEVICES 有权
标题翻译：方法和使用的设备具有流体脱气液体的增强消融设备
公开(公告)号：EP2696788A1
公开(公告)日：2014-02-19
申请号：EP12771601.7
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B18/04 , A61B18/08 , A61M37/00 , A61M25/01
CPC分类号： A61B18/04 , A61B18/082 , A61B18/1477 , A61B18/16 , A61B2017/00526 , A61B2018/00029 , A61B2018/00041 , A61B2018/00577 , A61B2018/00642 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/00821 , A61B2018/046 , A61B2018/1425 , A61B2018/162 , F04B17/03 , F04B19/22 , F04B43/04 , F04B49/06 , F04C2270/041 , Y10T29/49016 , Y10T29/49085
摘要： Devices and methods for monitoring the temperature of tissue at various locations in a treatment volume during fluid enhanced ablation therapy are provided. In one embodiment, an ablation device is provided having an elongate body, at least one ablation element, and at least one temperature sensor. The elongate body includes a proximal and distal end, an inner lumen, and at least one outlet port to allow fluid to be delivered to tissue surrounding the elongate body. The at least one ablation element is configured to heat tissue surrounding the at least one ablation element. The at least one temperature sensor can be positioned a distance away from the at least one ablation element and can be effective to output a measured temperature of tissue spaced a distance apart from the at least one ablation element such that the measured temperature indicates whether tissue is being heating to a therapeutic level.
摘要翻译：提供用于监测组织的温度保持在流体增强消融治疗过程中以治疗量的各个位置的装置和方法。在一个，消融装置的实施例，提供在细长体，至少一个消融元件，和至少一个温度传感器具有。该细长主体包括近端和远端的内腔和至少一个出口端口，以允许流体被输送到围绕细长主体的组织。所述至少一个消融元件被配置以加热组织围绕所述至少一个消融元件。所述至少一个温度传感器可以是距离该至少一个消融元件定位并且能够有效地输出组织的测量温度从检查所述至少一个消融元件隔开的距离做的测量的温度指示是否组织是被加热到治疗水平。

9. 发明公开

EP2696789A1 DEVICES AND METHODS FOR SHAPING THERAPY IN FLUID ENHANCED ABLATION 有权
标题翻译：用于流体增强消融成形治疗的装置和方法
公开(公告)号：EP2696789A1
公开(公告)日：2014-02-19
申请号：EP12770537.4
申请日：2012-04-12
申请人： Thermedical, Inc.
发明人： CURLEY, Michael, G.
IPC分类号： A61B18/12 , A61B18/08 , A61M37/00 , A61M25/01
CPC分类号： A61B18/04 , A61B18/082 , A61B18/1477 , A61B18/16 , A61B2017/00526 , A61B2018/00029 , A61B2018/00041 , A61B2018/00577 , A61B2018/00642 , A61B2018/00773 , A61B2018/00791 , A61B2018/00797 , A61B2018/00809 , A61B2018/00821 , A61B2018/046 , A61B2018/1425 , A61B2018/162 , F04B17/03 , F04B19/22 , F04B43/04 , F04B49/06 , F04C2270/041 , Y10T29/49016 , Y10T29/49085
摘要： Devices and methods for monitoring the temperature of tissue at various locations in a treatment volume during fluid enhanced ablation therapy are provided. In one embodiment, an ablation device is provided having an elongate body, at least one ablation element, and at least one temperature sensor. The elongate body includes a proximal and distal end, an inner lumen, and at least one outlet port to allow fluid to be delivered to tissue surrounding the elongate body. The at least one ablation element is configured to heat tissue surrounding the at least one ablation element. The at least one temperature sensor can be positioned a distance away from the at least one ablation element and can be effective to output a measured temperature of tissue spaced a distance apart from the at least one ablation element such that the measured temperature indicates whether tissue is being heating to a therapeutic level.
摘要翻译：提供了用于成形在流体增强消融治疗中形成的消融治疗容积的装置和方法。本文公开的装置和方法利用流体的相互作用来产生具有多种形状的消融治疗体积。在一个实施例中，用于形成具有期望形状的消融治疗体积的方法包括将治疗能量递送至组织以形成消融治疗体积并同时将第一流体和第二流体递送至组织。第一流体和第二流体可以沿期望的方向对流治疗能量，使得消融治疗体积具有期望的形状。

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