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1. 发明公开

EP3204773A1 METHODS AND DEVICES FOR REAL-TIME DIAGNOSTIC TESTING (RDT) FOR EBOLA AND OTHER INFECTIOUS DISEASES 审中-公开
标题翻译：用于埃博拉病和其它传染病的实时诊断测试（RDT）的方法和设备
公开(公告)号：EP3204773A1
公开(公告)日：2017-08-16
申请号：EP15849038.3
申请日：2015-10-08
申请人： Theranos, Inc.
发明人： YOUNG, Daniel , HOLMES, Elizabeth
IPC分类号： G01N33/569 , C12Q1/68
CPC分类号： C12Q1/6804 , C12Q1/6846 , C12Q1/70 , G01N33/56983 , G01N33/6854 , G01N2333/08 , G01N2469/20 , Y02A50/51 , Y02A50/52 , Y02A50/53 , Y02A50/58 , Y02A50/59 , C12Q2531/119 , C12Q2563/131 , C12Q2563/137 , C12Q2563/157 , C12Q2565/625 , C12Q2565/629
摘要： Methods, devices, systems, and kits for use in detecting and measuring infectious diseases are provided. In particular embodiments, methods, devices, systems, and kits for detecting and measuring Ebola virus, including Ebola Zaire strain virus, are provided. Devices and systems may be used within regions suffering from Ebola or other infections, providing local, rapid, and effective diagnosis of infectious diseases such as Ebola, improving treatment and reducing or preventing spread of such infectious diseases.
摘要翻译：提供了用于检测和测量传染病的方法，装置，系统和试剂盒。在具体的实施方案中，提供了用于检测和测量埃博拉病毒的方法，装置，系统和试剂盒，包括埃博拉扎伊尔株病毒。设备和系统可用于患埃博拉病毒或其他感染的地区，为埃博拉病毒等传染病提供局部，快速和有效的诊断，改善治疗并减少或预防传染病的传播。

2. 发明公开

EP3359115A1 BODILY FLUID SAMPLE COLLECTION AND TRANSPORT 无效转让
公开(公告)号：EP3359115A1
公开(公告)日：2018-08-15
申请号：EP16854509.3
申请日：2016-10-07
申请人： Theranos, Inc.
发明人： HOLMES, Elizabeth , LUI, Clarissa , CHEN, Michael , YOUNG, Daniel
IPC分类号： A61J1/05 , G01N1/28
CPC分类号： B01L9/06 , B01L3/502 , B01L3/5025 , B01L3/545 , B01L2200/185 , B01L2300/021 , B01L2300/022 , B01L2300/044 , B01L2300/0832 , B01L2300/0864 , B01L2400/0409 , G01N1/28
摘要： Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.

3. 发明公开

EP3155420A2 METHODS, DEVICES, AND SYSTEMS FOR SAMPLE ANALYSIS 无效转让
标题翻译： VERFAHREN，VORRICHTUNGEN UND SYSTEME ZUR PROBENANALYSE
公开(公告)号：EP3155420A2
公开(公告)日：2017-04-19
申请号：EP15807539.0
申请日：2015-06-10
申请人： Theranos, Inc.
发明人： YOUNG, Daniel , HOLMES, Elizabeth
IPC分类号： G01N33/483 , G01N35/00
CPC分类号： G01N33/492 , G01N15/06 , G01N15/1056 , G01N15/1475 , G01N33/4915 , G01N2015/0687 , G01N2015/0693 , G01N2015/1006 , G01N2015/1488 , G01N2015/1493 , G01N2015/1497
摘要： Methods, devices, and systems for analyzing biological samples for the presence of an analyte by an initial assay, and, contingent upon the results of the initial assay, by a subsequent assay are provided. A sample may be diluted. A portion of a sample may be retained for use in such a subsequent assay. Initial assay results may be used to determine, for example, one or more of: whether or not a subsequent assay is performed; which subsequent assay is performed; the method of performing a subsequent assay; the order of performance of a sequence of subsequent assays; the steps, or order of steps, performed in a subsequent assay; the timing of the performance of a subsequent assay; the choice of a reagent used in a subsequent assay; the detection method used in a subsequent assay; and other particulars of assays may be contingent on the results of a prior assay.
摘要翻译：提供了通过初始测定分析生物样品中分析物存在的方法，装置和系统，并且依照初始测定的结果，通过随后的测定。样品可能被稀释。样品的一部分可以保留用于这样的后续测定。初步测定结果可用于确定例如以下中的一种或多种：是否进行随后的测定; 进行后续测定; 进行后续测定的方法; 后续测定序列的性能顺序; 在随后的测定中进行的步骤或步骤顺序; 随后测定的时间表; 在随后测定中使用的试剂的选择; 在随后的测定中使用的检测方法; 测定的其它细节可能取决于先前测定的结果。

4. 发明公开

EP3325160A1 SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION, TRANSPORT, AND HANDLING 无效转让
公开(公告)号：EP3325160A1
公开(公告)日：2018-05-30
申请号：EP16828579.9
申请日：2016-07-21
申请人： Theranos, Inc.
发明人： HOLMES, Elizabeth , LUI, Clarissa , CHEN, Michael , YOUNG, Daniel , ANEKAL, Samartha
IPC分类号： B01L3/14 , A61J1/05 , G01N1/28
CPC分类号： A61J1/05 , A61B5/150022 , A61B5/15003 , A61B5/150099 , A61B5/150251 , A61B5/150305 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150572 , A61B5/150732 , A61B5/150755 , A61B5/150793 , A61B5/150824 , A61B5/150954 , A61B5/150984 , A61B5/150992 , A61B5/15109 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/154 , A61J1/03 , B01L3/14 , B01L3/5021 , B01L9/06 , G01N1/4077 , G01N33/491 , G01N2001/4083
摘要： Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step.

5. 发明公开

EP2666008A2 SYSTEMS AND METHODS FOR SAMPLE USE MAXIMIZATION 有权转让
标题翻译：系统VERFAHREN ZUR MAXIMIERUNG DER VERWENDUNG EINER PROBE
公开(公告)号：EP2666008A2
公开(公告)日：2013-11-27
申请号：EP12737013.8
申请日：2012-01-20
申请人： Theranos, Inc.
发明人： GIBBONS, Ian , NUGENT, Tony , DELACRUZ, Anthony , YOUNG, Daniel , HOLMES, Elizabeth , DRAKE, Andrew , KEMP, Timothy, Michael , BALWANI, Sunny , PANGARKAR, Chinmay
IPC分类号： G01N21/05 , C12Q1/00
CPC分类号： G01N21/00 , B01L3/0275 , B01L2300/168 , B04B5/0421 , C12Q1/42 , C12Q1/48 , C12Q1/52 , C12Q1/6806 , C12Q1/6809 , C12Q1/689 , C12Q2600/158 , G01N1/4077 , G01N21/0303 , G01N21/51 , G01N21/59 , G01N33/5308 , G01N33/54326 , G01N33/54393 , G01N33/56972 , G01N33/56983 , G01N33/573 , G01N33/74 , G01N33/743 , G01N33/80 , G01N33/82 , G01N33/92 , G01N35/10 , G01N2001/4083 , G01N2035/00495 , G01N2333/575 , G01N2333/62 , G01N2333/91188 , G01N2333/96463 , G06F19/703 , G06T3/4084 , G06T7/0002 , G06T7/0012 , G06T2207/30004 , G06T2207/30168 , H04N5/23222
摘要： The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
摘要翻译：本发明提供了用于点护理和/或分布式测试服务的系统，设备和方法。本发明的方法和装置旨在自动检测体液中的分析物。可以对装置的部件进行修改，以允许用于各种医疗，实验室和其它应用的所公开的方法的更灵活和可靠的使用。本发明的系统，装置和方法可以通过改进的样品制备和分析来允许样品的有效使用。

6. 发明公开

EP3111372A1 SYSTEMS, DEVICES, AND METHODS FOR SAMPLE INTEGRITY VERFICATION 有权转让
标题翻译：系统，设备和样品的完整性检测方法
公开(公告)号：EP3111372A1
公开(公告)日：2017-01-04
申请号：EP15754417.2
申请日：2015-02-25
申请人： Theranos, Inc.
发明人： MORRISON, Zachary , YOUNG, Daniel , BALWANI, Sunny
IPC分类号： G06K9/20 , G01N21/00
CPC分类号： G02B21/367 , G01N21/03 , G01N35/00732 , G01N35/00871 , G01N2035/00891 , G01N2201/12 , G02B7/1821 , G02B21/0004 , G02B21/06 , G02B21/34 , G02B21/361 , G02B21/362 , G02B21/365
摘要： The devices, systems, and methods disclosed herein provide sample verification capabilities in a single device or system. Devices are disclosed herein. Systems including these devices are also provided. These devices and systems may be configured for verifying sample integrity prior to a subject leaving a sample collection site so that any further samples or other corrective action can occur without having to make a separate visit.
摘要翻译：在游离缺失的装置，系统，和方法提供盘在单个设备中或系统样品验证能力。设备是光盘游离缺失。因此，提供包含合成器件的系统。这些设备和系统可以被配置为一个主题之前，验证样品的完整性留下样本采集网站，所以没有任何进一步的样品或其他纠正动作，而无需进行单独的访问，可能会发生。

7. 发明公开

EP2928374A2 SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION AND TRANSPORT 有权
标题翻译：系统，设备和收集和运输的体液样本方法
公开(公告)号：EP2928374A2
公开(公告)日：2015-10-14
申请号：EP13860491.3
申请日：2013-12-05
申请人： Theranos, Inc.
发明人： HOLMES, Elizabeth, A. , LUI, Clarissa , CHEN, Michael , YOUNG, Daniel
IPC分类号： A61B5/155 , G01N1/18 , G01N33/48
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/15003 , A61B5/150099 , A61B5/150251 , A61B5/150305 , A61B5/150755 , A61B5/150984 , A61B5/150992 , A61B5/154 , A61B5/157 , A61B90/90 , A61B90/94 , A61B90/98 , G01N33/491
摘要： Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

8. 发明公开

EP2874754A1 HIGH SPEED, COMPACT CENTRIFUGE FOR USE WITH SMALL SAMPLE VOLUMES 有权转让
标题翻译：快速，紧凑离心小样本卷使用
公开(公告)号：EP2874754A1
公开(公告)日：2015-05-27
申请号：EP13820681.8
申请日：2013-07-18
申请人： Theranos, Inc.
发明人： HOLMES, Elizabeth, A. , YOUNG, Daniel , SMITH, Timothy , RIDEL, Scott , FRANKOVICH, John Kent , SIEGEL, Michael
IPC分类号： B04B13/00 , B04B9/00
CPC分类号： G01D5/145 , B04B5/0421 , B04B7/08 , B04B9/10 , B04B9/14 , B04B13/00 , B04B15/02 , G01D5/3473 , G01P3/488
摘要： In one nonlimiting example, an automated system is provided for separating one or more components in a biological fluid, wherein the system comprises: (a) a centrifuge comprising one or more bucket configured to receive a container to effect said separating of one or more components in a fluid sample; and (b) the container, wherein the container includes one or more shaped feature that is complementary to a shaped feature of the bucket.

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