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1. 发明授权

EP0538990B1 Apparatus and method for antitachycardia pacing using a virtual electrode 失效
标题翻译：装置和方法，用于通过一个虚拟电极的手段治疗心动过速
公开(公告)号：EP0538990B1
公开(公告)日：1999-07-07
申请号：EP92306737.5
申请日：1992-07-23
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Lu, Richard M.T. , Collins, Kenneth Andrew , McCulloch, Roy Murray , Cheatle, Lucy Margaret , Cleland, Brian
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/3622 , A61N1/3918

2. 发明公开

EP0538990A2 Apparatus and method for antitachycardia pacing using a virtual electrode 失效
标题翻译：装置和方法，用于治疗使用的虚拟电极心动过速。
公开(公告)号：EP0538990A2
公开(公告)日：1993-04-28
申请号：EP92306737.5
申请日：1992-07-23
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Lu, Richard M.T. , Collins, Kenneth Andrew , McCulloch, Roy Murray , Cheatle, Lucy Margaret , Cleland, Brian
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/3622 , A61N1/3918
摘要： An implantable device (10) and method for treating cardia arrhythmias in a patient's heart (11) are disclosed. A source of antitachycardia pacing therapy and an electrode system including at least three electrodes (80, 83, 86) for delivering the antitachycardia pacing therapy to the heart are provided. Circuitry and software (17, 19) for detecting a tachycardia having a site of focus in the heart and for determining the relative distances of the electrodes from the focus site are also provided. The three or more electrodes are connected to the source of antitachycardia pacing therapy based on the relative distances determined and in such a manner as to create a virtual electrode at the focus site upon delivery of the therapy to the heart.
摘要翻译：一种用于在患者的心脏（11）治疗心律失常贲门的可植入装置（10）和方法是游离缺失盘。抗心动过速起搏治疗的源极和与电极系统，其包括至少三个电极（80，83，86）用于递送抗心动过速起搏治疗的心脏中提供。电路和用于检测具有焦点的在心脏和用于确定性采矿因此，提供从焦点位点电极的相对距离的部位的心动过速软件（17，19）。所述三个或更多的电极连接到基于所述相对距离确定的开采抗心动过速起搏治疗的源极和在寻求其方式是在递送治疗心脏的创建在现场焦点虚拟电极。

3. 发明授权

EP0465241B1 Apparatus for the detection and treatment of arrhythmias using neural networks 失效
标题翻译：设备与检测和治疗心律失常的神经网络
公开(公告)号：EP0465241B1
公开(公告)日：1998-11-04
申请号：EP91306051.3
申请日：1991-07-03
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Drane, Geoff , Flower, Barry , Lunsmann, Paul , Dodd, Robert , Bassin, David , Wickham, John , Murphy, Tony
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/36514 , A61N1/3962

4. 发明公开

EP0538990A3 Apparatus and method for antitachycardia pacing using a virtual electrode 失效
标题翻译：使用虚拟电极进行抗虫药的装置和方法
公开(公告)号：EP0538990A3
公开(公告)日：1997-03-19
申请号：EP92306737.5
申请日：1992-07-23
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Lu, Richard M.T. , Collins, Kenneth Andrew , McCulloch, Roy Murray , Cheatle, Lucy Margaret , Cleland, Brian
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/3622 , A61N1/3918
摘要： An implantable device (10) and method for treating cardia arrhythmias in a patient's heart (11) are disclosed. A source of antitachycardia pacing therapy and an electrode system including at least three electrodes (80, 83, 86) for delivering the antitachycardia pacing therapy to the heart are provided. Circuitry and software (17, 19) for detecting a tachycardia having a site of focus in the heart and for determining the relative distances of the electrodes from the focus site are also provided. The three or more electrodes are connected to the source of antitachycardia pacing therapy based on the relative distances determined and in such a manner as to create a virtual electrode at the focus site upon delivery of the therapy to the heart.

5. 发明公开

EP0465241A3 Apparatus and method for the detection and treatment of arrhythmias using a neural network 失效
标题翻译：使用神经网络检测和治疗脑脊髓的装置和方法
公开(公告)号：EP0465241A3
公开(公告)日：1994-06-29
申请号：EP91306051.3
申请日：1991-07-03
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Drane, Geoff , Flower, Barry , Lunsmann, Paul , Dodd, Robert , Bassin, David , Wickham, John , Murphy, Tony
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/36514 , A61N1/3962
摘要： An apparatus and method for the detection and treatment of arrhythmias using a processor having a neural network (21) with a hierarchical arrangement including a first lower level (21A) for classifying individual waveforms, a second higher level (21B) for diagnosing detected arrhythmias and a third higher level (21C) for the application of therapy in response to a diagnosed arrhythmia. The neural network (21) may be a back propogation neural network or an associative memory type neural network. The arrhythmias detected may be at least one of bradycardia, tachycardia and fibrillation. The apparatus may include a cardioverting/defibrillating packmaker (15). In general, the apparatus acquires physiological signals representative of heart activity in a patient. A neural network (21) receives the physiological signals and determines if any arrhythmia is present, and if present, selects therapy to be applied to the heart. A therapy generator then applies the therapy selected by the neural network (21). The physioligical signals may be processed or unprocessed ECG signal, signals indicative of the properties of the blood, and blood flow signals or signals representative of ventricular wall impedance or ventricular volume.

6. 发明公开

EP0465241A2 Apparatus and method for the detection and treatment of arrhythmias using a neural network 失效
标题翻译：装置和方法有用于心律不齐的检测和治疗神经网络。
公开(公告)号：EP0465241A2
公开(公告)日：1992-01-08
申请号：EP91306051.3
申请日：1991-07-03
申请人： TELECTRONICS N.V.
发明人： Nickolls, Peter , Drane, Geoff , Flower, Barry , Lunsmann, Paul , Dodd, Robert , Bassin, David , Wickham, John , Murphy, Tony
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/36514 , A61N1/3962
摘要： An apparatus and method for the detection and treatment of arrhythmias using a processor having a neural network (21) with a hierarchical arrangement including a first lower level (21A) for classifying individual waveforms, a second higher level (21B) for diagnosing detected arrhythmias and a third higher level (21C) for the application of therapy in response to a diagnosed arrhythmia. The neural network (21) may be a back propogation neural network or an associative memory type neural network. The arrhythmias detected may be at least one of bradycardia, tachycardia and fibrillation. The apparatus may include a cardioverting/defibrillating packmaker (15). In general, the apparatus acquires physiological signals representative of heart activity in a patient. A neural network (21) receives the physiological signals and determines if any arrhythmia is present, and if present, selects therapy to be applied to the heart. A therapy generator then applies the therapy selected by the neural network (21). The physioligical signals may be processed or unprocessed ECG signal, signals indicative of the properties of the blood, and blood flow signals or signals representative of ventricular wall impedance or ventricular volume.
摘要翻译：用于检测和治疗使用具有分层布置，其包括用于各个波形进行分类的第一下部水平（21A）一个神经网络（21）的处理器心律失常的装置和方法，第二较高水平（21B）用于诊断检测心律失常和用于治疗响应于诊断心律失常的应用的第三更高的水平（图21C）。神经网络（21）可以是一个回传播史神经网络或相关存储器类型神经网络。检测到的心律失常可以是心动过缓，心动过速和纤维性颤动中的至少一个。该装置可以包括一个复律/除颤包机（15）。一般而言，装置获取生理代表心脏活动的患者中的信号。神经网络（21）接收生理信号而确定的地雷如果任何心律失常存在，并且如果存在的话，治疗选择将被施加到心脏。甲治疗发生器然后应用由神经网络（21）所选择的治疗。所述physioligical信号可以被处理或未经处理的ECG信号，信号指示所述血液的特性，和有代表性的心室壁阻抗或心室体积的血流信号或信号。

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