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1. 发明公开

EP0773038A2 Improved graphic interface for pacemaker programmers 失效
标题翻译： Verbesserte graphische SchnittstellefürProgrammiereinrichtungenfürHerzschrittmacher
公开(公告)号：EP0773038A2
公开(公告)日：1997-05-14
申请号：EP96307877.9
申请日：1996-10-30
申请人： TELECTRONICS N.V.
发明人： Nappholz, Tibor A. , Steinhaus, Bruce , Chiang, Chih-ming James , Bernstein, Alan D.
IPC分类号： A61N1/372
CPC分类号： A61N1/37247
摘要： A graphic user interface (P) for a cardiac implant, such as an implant programmer (38), includes image generators (24, 26) for generating multiple images on a screen (16), each image corresponding to as representation of a parameter related to the operation of the implant (38) or a cardiac function, and an indicia generator (27) for superimposing on the images an indicia indicative of the interrelation between the parameters. The indicia allows a user to obtain a clear understanding and appreciation of the cause and effect rules between various cardiac parameters and/or functions, the parameters or functions could be actual, i.e., obtained from the implant (38) and/or the patient's heart, or they can be simulated to provide the user an indication on how the pacemaker will operate under these simulated conditions parameters.
摘要翻译：用于心脏植入物的图形用户界面（P），例如植入物编程器（38），包括用于在屏幕（16）上生成多个图像的图像生成器（24,26），每个图像对应于参数相关的表示涉及植入物（38）或心脏功能的操作，以及用于将指示在参数之间的相互关系的标记叠加在图像上的标记产生器（27）。标记允许用户获得对各种心脏参数和/或功能之间的因果关系规则的清楚的理解和欣赏，参数或功能可以是实际的，即从植入物（38）和/或患者的心脏获得，或者它们可以被模拟以向用户提供关于起搏器在这些模拟条件参数下如何操作的指示。

2. 发明公开

EP0627194A2 A leadless implantable cardiac emergency warning alarm 失效
标题翻译： Implantierbare elektrodenlose Herzalarmeinheit。
公开(公告)号：EP0627194A2
公开(公告)日：1994-12-07
申请号：EP94304004.8
申请日：1994-06-03
申请人： TELECTRONICS N.V.
发明人： Nolan, James A. , Steinhaus, Bruce M. , Nappholz, Tibor A.
IPC分类号： A61B5/0464 , A61B5/046
CPC分类号： A61B5/0006 , A61B5/0464 , A61B5/7207
摘要： A leadless implantable cardiac arrhythmia alarm is disclosed which continuously assesses a patient's heart function to discriminate between normal and abnormal heart functioning and, upon detecting an abnormal condition, generates a patient-warning signal. The alarm (5) is capable of sensing impedance measurements of heart, respiratory and patient motion and, from these measurements, generating an alarm signal when the measurements indicate the occurrence of a cardiac arrhythmia. Because it requires no external leads or feedthrough connectors, the hermetically-sealed patient alarm (5) is minimally invasive and results in reduced trauma to a patient.
摘要翻译：公开了一种无引力植入式心律失常警报器，其连续评估患者的心脏功能以区分正常和异常心脏功能，并且在检测到异常状况时产生患者警告信号。该报警器能够感测心脏，呼吸和患者运动的阻抗测量，并且在这些测量中，当测量指示心律失常的发生时产生报警信号。因为它不需要外部引线或馈通连接器，所以密封的患者警报器是微创的并且导致对患者的创伤减少。

3. 发明公开

EP0582087A1 Minute volume rate-responsive pacemaker 失效
标题翻译： Schrittmacher，bei dem die Frequenz vom Herzminutenvolumenabhängigist。
公开(公告)号：EP0582087A1
公开(公告)日：1994-02-09
申请号：EP93110579.5
申请日：1989-01-30
申请人： TELECTRONICS N.V.
发明人： Nappholz, Tibor A. , Hamilton, John R. , Hansen, James C.
IPC分类号： A61N1/365 , A61N1/368 , A61B5/08
CPC分类号： A61N1/368 , A61N1/36514 , A61N1/36521
摘要： The present invention provides a rate-responsive packmaker (10-28) whose rate control parameter is minute volume derived over a bipolar lead (10, 12). An algorithm based on averaged samples and zero crossings provides enhanced accuracy. Sustained exercise at high pacing rates is possible.
摘要翻译：本发明提供了速率控制参数是通过双极引线（10,12）导出的微小体积的速率响应型压缩机（10-28）。基于平均采样和零交叉的算法提高了精度。以高起搏率持续运动是可能的。

4. 发明公开

EP0503285A1 A catheter-mounted doppler ultrasound transducer and signal processor 失效
标题翻译：装置，用于为一体，安装在导管中，多普勒超声换能器信号处理。
公开(公告)号：EP0503285A1
公开(公告)日：1992-09-16
申请号：EP92102222.4
申请日：1992-02-10
申请人： TELECTRONICS N.V.
发明人： Valenta, Harry L., Jr. , Nappholz, Tibor A.
IPC分类号： A61B8/06
CPC分类号： A61B8/06 , A61B8/12 , A61B8/445 , A61N1/36528 , A61N1/36571
摘要： A Doppler ultrasound transducer (92) and interconnected high frequency signal processing circuit (70), adapted for operative coupling on a distal portion of an intravascular catheter (13), for ultrasonically sensing high frequency signals representative of blood flow within a patient's cardiovascular system (83), processing these high frequency signals into baseband audio signals, and communicating these audio signals to associated low frequency signal processing circuitry located in the proximal portion of the catheter by modulating the load current of a power supply within the high frequency circuit.
摘要翻译：多普勒超声换能器（92）和相互连接的高频信号处理电路（70），适于可操作耦合上的远端部分（血管内导管（13），用于超声感测患者的心血管系统内的代表性的血流的高频信号 83），则处理论文高频信号转换成基带音频信号，和通信合成音频信号到位于该导管的近端部分通过调制高频电路内的电源的负载电流相关联的低频信号处理电路。

5. 发明授权

EP0576114B1 Multiple parameter rate-responsive cardiac stimulation apparatus 失效
标题翻译：多个参数的依赖性，起搏速率自适应起搏器
公开(公告)号：EP0576114B1
公开(公告)日：2001-03-14
申请号：EP93300650.4
申请日：1993-01-28
申请人： TELECTRONICS N.V.
发明人： Steinhaus, Bruce M. , Nappholz, Tibor A. , Nolan, James A. , Morris, Robert A. , Koestner, Ken
IPC分类号： A61N1/365 , A61N1/37
CPC分类号： A61N1/36521

6. 发明公开

EP0555988A2 Minute volume rate-responsive packmaker employing impedance sensing on a unipolar lead 失效
标题翻译：通过测量极依赖于微小体积阻抗控制起搏器。
公开(公告)号：EP0555988A2
公开(公告)日：1993-08-18
申请号：EP93300798.1
申请日：1993-02-03
申请人： TELECTRONICS N.V.
发明人： Steinhaus, Bruce M. , Nappholz, Tibor A. , Nolan, James A. , Morris, Robert A.
IPC分类号： A61N1/365
CPC分类号： A61N1/36521
摘要： A rate-responsive pacemaker (5) employing a rate control parameter of respiratory minute volume, derived over a unipolar lead (11). The pacemaker (5) performs the minute volume measurement by periodically applying a measuring current between the lead and a reference point on the pacemaker case (30). This measuring current has frequency components in a range from approximately 10 kilohertz to 1000 megahertz. Application of this measuring current allows the pacemaker to detect the voltage which arises from the applied current and, from the detected voltage, to measure the patient's spatial impedance. Spatial impedance and minute volume vary as a function of the patient's pleural pressure. The pacemaker (5) derives minute volume and rate-responsive pacing rate from the spatial impedance measurement.
摘要翻译：一种速率响应起搏器（5）使用每分钟呼吸量的速率控制参数，导出在单极导线（11）。起搏器（5）通过周期性地施加所述引线和所述起搏器壳体（30）的参考点之间的测量电流进行微小体积的测量。该测量电流具有的频率分量在从大约10千赫兹至1000兆赫兹的范围内。该测量电流的应用允许起搏器以检测从所施加的电流和辨正，从检测到的电压的电压，以测量患者的空间阻抗。空间阻抗和微小体积变化作为患者的胸膜压力的函数。起搏器（5）导出分钟体积和速率响应起搏速率从空间阻抗测量。

7. 发明公开

EP0472411A1 Implantable ambulatory electrocardiogram monitor 失效
标题翻译： ImplantierbaresÜberwachungssystemfürambulante Elektrokardiographie。
公开(公告)号：EP0472411A1
公开(公告)日：1992-02-26
申请号：EP91307673.3
申请日：1991-08-21
申请人： TELECTRONICS N.V.
发明人： Nappholz, Tibor A. , Hursta, William N. , Dawson, Albert K. , Steinhaus, Bruce M.
IPC分类号： A61B5/07 , A61B5/0402
CPC分类号： A61N1/37264 , A61B5/0006 , A61B5/0031 , A61B5/7207 , A61B5/7232 , A61N1/37211 , A61N1/37258 , G06F19/00 , Y10S128/903
摘要： An implanted programmable ambulatory electrocardiography (AECG) patient monitoring device that senses and analyzes electrocardiographic signals from at least one subcutaneous precordial sensor chronically and frequently to detect electrocardiogram and physiological signal characteristics predictive of malignant cardiac arrhythmias. The device includes telemetric capabilities to communicate a warning signal to an external device when such arrhythmias are predicted.
摘要翻译：植入式可编程动态心电图（AECG）患者监测装置，其可以长期和频繁地感测和分析来自至少一个皮下心前传感器的心电图信号，以检测预测恶性心律失常的心电图和生理信号特征。当预测出这种心律失常时，该装置包括用于将警告信号传送到外部设备的遥测功能。

8. 发明授权

EP0327292B2 Minute volume rate-responsive pacemaker 失效
标题翻译：按分钟容积率应答起搏器控制
公开(公告)号：EP0327292B2
公开(公告)日：2001-11-14
申请号：EP89300895.3
申请日：1989-01-30
申请人： TELECTRONICS N.V.
发明人： Nappholz, Tibor A. , Hamilton, John R. , Hansen, James C.
IPC分类号： A61N1/365 , A61B5/08
CPC分类号： A61N1/368 , A61N1/36514 , A61N1/36521

9. 发明公开

EP0627194A3 A leadless implantable cardiac emergency warning alarm 失效
标题翻译：植入式心脏无极报警单元。
公开(公告)号：EP0627194A3
公开(公告)日：1996-05-08
申请号：EP94304004.8
申请日：1994-06-03
申请人： TELECTRONICS N.V.
发明人： Nolan, James A. , Steinhaus, Bruce M. , Nappholz, Tibor A.
IPC分类号： A61B5/0464 , A61B5/046
CPC分类号： A61B5/0006 , A61B5/0464 , A61B5/7207
摘要： A leadless implantable cardiac arrhythmia alarm is disclosed which continuously assesses a patient's heart function to discriminate between normal and abnormal heart functioning and, upon detecting an abnormal condition, generates a patient-warning signal. The alarm (5) is capable of sensing impedance measurements of heart, respiratory and patient motion and, from these measurements, generating an alarm signal when the measurements indicate the occurrence of a cardiac arrhythmia. Because it requires no external leads or feedthrough connectors, the hermetically-sealed patient alarm (5) is minimally invasive and results in reduced trauma to a patient.

10. 发明授权

EP0327292B1 Minute volume rate-responsive pacemaker 失效
标题翻译：通过分时量脉搏控制起搏器。
公开(公告)号：EP0327292B1
公开(公告)日：1994-08-03
申请号：EP89300895.3
申请日：1989-01-30
申请人： TELECTRONICS N.V.
发明人： Nappholz, Tibor A. , Hamilton, John R. , Hansen, James C.
IPC分类号： A61N1/365 , A61B5/08
CPC分类号： A61N1/368 , A61N1/36514 , A61N1/36521

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