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1. 发明公开

EP0429304A3 Pyridone-carboxylic acid derivatives and their use as veterinary medicines 失效
标题翻译：吡咯烷酮羧酸衍生物及其作为兽药的用途
公开(公告)号：EP0429304A3
公开(公告)日：1991-08-14
申请号：EP90312692.8
申请日：1990-11-21
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Imose, Jun , Kataoka, Takahiro , Hidaka, Shigetada , Ueda, Kazuo , Ogata, Masaru , Takahashi, Toshio
IPC分类号： C07D401/04 , C07D471/04 , C07D498/06
CPC分类号： C07D401/04 , C07D471/04
摘要： A veterinary composition for the treatment or prophylaxis of infectious diseases caused by infectious microorganisms which comprises at least one pyridone-carboxylic acid compound of the formula:
wherein
R¹ is lower alkyl, halo(lower)alkyl, cyclo(lower) alkyl or substituted or unsustituted phenyl;
R² and R³ are each hydrogen, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁵)R⁶ (in which R⁵ and R⁶ are each hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl);
R⁴ is hydrogen, oxo, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁷)R⁸ (in which R⁷ and R⁸ are each hydrogen or lower alkyl;
X is hydrogen or halogen;
Y is CQ (in which Q is hydrogen or halogen) or nitrogen or, when taken together with R¹, may form a group of the formula: =C-OCH₂C(R⁹)H- (in which R⁹ is hydrogen or lower alkyl and the carbon atom to which R⁹ is attached links to the nitrogen atom in the pyridone ring); the compound themselves and a process for their production.

2. 发明公开

EP0429304A2 Pyridone-carboxylic acid derivatives and their use as veterinary medicines 失效
标题翻译： Pyridon-Carbonsäurederivateund ihre Verwendung als Tierarzneimittel。
公开(公告)号：EP0429304A2
公开(公告)日：1991-05-29
申请号：EP90312692.8
申请日：1990-11-21
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Imose, Jun , Kataoka, Takahiro , Hidaka, Shigetada , Ueda, Kazuo , Ogata, Masaru , Takahashi, Toshio
IPC分类号： C07D401/04 , C07D471/04 , C07D498/06
CPC分类号： C07D401/04 , C07D471/04
摘要： A veterinary composition for the treatment or prophylaxis of infectious diseases caused by infectious microorganisms which comprises at least one pyridone-carboxylic acid compound of the formula:
wherein
R¹ is lower alkyl, halo(lower)alkyl, cyclo(lower) alkyl or substituted or unsustituted phenyl;
R² and R³ are each hydrogen, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁵)R⁶ (in which R⁵ and R⁶ are each hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl);
R⁴ is hydrogen, oxo, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁷)R⁸ (in which R⁷ and R⁸ are each hydrogen or lower alkyl;
X is hydrogen or halogen;
Y is CQ (in which Q is hydrogen or halogen) or nitrogen or, when taken together with R¹, may form a group of the formula: =C-OCH₂C(R⁹)H- (in which R⁹ is hydrogen or lower alkyl and the carbon atom to which R⁹ is attached links to the nitrogen atom in the pyridone ring); the compound themselves and a process for their production.
摘要翻译：用于治疗或预防由感染性微生物引起的感染性疾病的兽用组合物，其包含至少一种下式的吡啶酮羧酸化合物：其中R 1为低级烷基，卤代（低级）烷基，环（低级））烷基或取代或未取代的苯基; R 2和R 3各自为氢，羟基，低级烷氧基，卤素或下式基团：-CH 2 N（R 5）R 6（其中R 5和R 6）各自为氢，低级烷基，低级烯基或羟基（低级）烷基）; R 4是氢，氧代，羟基，低级烷氧基，卤素或下式的基团：-CH 2 N（R 7）R 8（其中R 7和R 8各自是氢或低级烷基; X是氢或卤素; Y是CQ（其中Q是氢或卤素）或氮，或者当与R 1一起时可以形成下式的基团：= C-OCH 2 C（R 9） >）H-（其中R 9是氢或低级烷基，R 9连接的碳原子连接到吡啶酮环中的氮原子）;化合物本身及其制备方法。

3. 发明授权

EP0398692B1 Alkoxyiminoacetamide derivatives and their use as fungicides 失效
标题翻译：烷氧亚氨基衍生物和它们作为杀真菌剂使用
公开(公告)号：EP0398692B1
公开(公告)日：1996-08-21
申请号：EP90305303.1
申请日：1990-05-16
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Hayase, Yoshio , Kataoka, Takahiro , Takenaka, Hideyuki , Ichinari, Mitsuhiro , Masuko, Michio , Takahashi, Toshio , Tanimoto, Norihiko
IPC分类号： C07C251/48 , A01N37/50 , C07C323/57 , C07C317/44 , C07D239/34 , C07C323/63 , C07F7/10 , C07D213/643 , C07D309/12 , C07D277/68 , C07D215/227
CPC分类号： C07C249/12 , A01N37/50 , C07C251/48 , C07C317/44 , C07C323/60 , C07D213/64 , C07D215/227 , C07D239/34 , C07D277/68 , C07D303/46 , C07D307/36 , C07D307/40 , C07D307/42 , C07D309/12 , C07F7/10

4. 发明公开

EP0398692A2 Alkoxyiminoacetamide derivatives and their use as fungicides 失效
标题翻译：烷氧基亚氨基乙酰胺 - 衍生物和细胞培养物。
公开(公告)号：EP0398692A2
公开(公告)日：1990-11-22
申请号：EP90305303.1
申请日：1990-05-16
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Hayase, Yoshio , Kataoka, Takahiro , Takenaka, Hideyuki , Ichinari, Mitsuhiro , Masuko, Michio , Takahashi, Toshio , Tanimoto, Norihiko
IPC分类号： C07C251/48 , A01N37/50 , C07C323/57 , C07C317/44 , C07D239/34 , C07C323/63 , C07F7/10 , C07D213/643 , C07D309/12 , C07D277/68 , C07D215/227
CPC分类号： C07C249/12 , A01N37/50 , C07C251/48 , C07C317/44 , C07C323/60 , C07D213/64 , C07D215/227 , C07D239/34 , C07D277/68 , C07D303/46 , C07D307/36 , C07D307/40 , C07D307/42 , C07D309/12 , C07F7/10
摘要： A fungicidal composition for agricultural use, which comprises a compound of the formula:
wherein R 1 and R 2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R 3 is lower alkyl or cyclo(lower)alkyl; R4 and R 5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, said phenyl group or heterocyclic group being optionally substituted with not more than three substituents; and Z is -CH 2 -, -CH(OH)-, -CO-, -O-, -S-, -SO-, -NR- (R being hydrogen or lower alkyl), -CH 2 CH 2 -, -CH = CH-,
-CH 2 0-, -CH 2 S-, CH 2 S0-, -OCH 2 -, -SCH 2 - or -SOCH 2 -.
摘要翻译：一种农业用杀真菌组合物，其包含下式化合物：其中R 1和R 2各自为氢，低级烷基或环（低级）烷基; R 3是低级烷基或环（低级）烷基; R 4和R 5各自为氢，低级烷基，低级烷氧基，卤素取代的低级烷基，低级烷基取代的甲硅烷基，卤素或硝基; A表示不饱和烃基，卤素取代的不饱和烃基，苯基或杂环基，所述苯基或杂环基任选被不多于三个取代基取代; 且Z为-CH 2 - ， - CH（OH） - ， - CO - ， - O - ， - S - ， - SO - ， - NR-（R为氢或低级烷基） - ，CH 2 -CH 2 - ， - CH 2 S - ，CH 2 SO - ， - OCH 2 - ， - CH 2 - 或-SOCH 2 - 。米

5. 发明公开

EP0629609A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor 失效
标题翻译：烷氧基亚氨基乙酰胺 - 衍生物和Verwendung als Fungizide。
公开(公告)号：EP0629609A1
公开(公告)日：1994-12-21
申请号：EP94111766.5
申请日：1990-05-16
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Hayase, Yoshio , Kataoka, Takahiro , Takenaka, Hideyuki , Ichinari, Mitsuhiro , Masuko, Michio , Takahashi, Toshio , Tanimoto, Norihiko
IPC分类号： C07C249/12 , C07C251/48 , C07D213/64 , C07D239/34 , C07D251/22 , A01N37/50
CPC分类号： C07C249/12 , A01N37/50 , C07C251/48 , C07C317/44 , C07C323/60 , C07D213/64 , C07D215/227 , C07D239/34 , C07D277/68 , C07D303/46 , C07D307/36 , C07D307/40 , C07D307/42 , C07D309/12 , C07F7/10
摘要： A process for preparing a compound of the formula:

wherein A is a phenyl group or a heterocyclic group, said phenyl group and said heterocyclic group being optionally substituted with not more than three substituents, which comprises reacting a compound of the formula:

with an aryl halide in the presence of a base. The resulting compound (A) is useful as a fungicide. There is also disclosed a compound of the formula:
摘要翻译：一种制备下式化合物的方法：其中A是苯基或杂环基，所述苯基和所述杂环基任选被不多于三个取代基取代，其包括使下式化合物：与芳基卤在碱的存在下反应。所得化合物（A）可用作杀真菌剂。还公开了下式的化合物：

6. 发明公开

EP0398692A3 Alkoxyiminoacetamide derivatives and their use as fungicides 失效
标题翻译：烷氧基胺酰胺衍生物及其作为防腐剂使用
公开(公告)号：EP0398692A3
公开(公告)日：1991-05-29
申请号：EP90305303.1
申请日：1990-05-16
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Hayase, Yoshio , Kataoka, Takahiro , Takenaka, Hideyuki , Ichinari, Mitsuhiro , Masuko, Michio , Takahashi, Toshio , Tanimoto, Norihiko
IPC分类号： C07C251/48 , A01N37/50 , C07C323/57 , C07C317/44 , C07D239/34 , C07C323/63 , C07F7/10 , C07D213/643 , C07D309/12 , C07D277/68 , C07D215/227
CPC分类号： C07C249/12 , A01N37/50 , C07C251/48 , C07C317/44 , C07C323/60 , C07D213/64 , C07D215/227 , C07D239/34 , C07D277/68 , C07D303/46 , C07D307/36 , C07D307/40 , C07D307/42 , C07D309/12 , C07F7/10
摘要： A fungicidal composition for agricultural use, which comprises a compound of the formula:
wherein R 1 and R 2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R 3 is lower alkyl or cyclo(lower)alkyl; R4 and R 5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, said phenyl group or heterocyclic group being optionally substituted with not more than three substituents; and Z is -CH 2 -, -CH(OH)-, -CO-, -O-, -S-, -SO-, -NR- (R being hydrogen or lower alkyl), -CH 2 CH 2 -, -CH = CH-,
-CH 2 0-, -CH 2 S-, CH 2 S0-, -OCH 2 -, -SCH 2 - or -SOCH 2 -.

7. 发明授权

EP0629609B1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor 失效
标题翻译：一种制备烷氧衍生物和用于Zwischenproduckt过程
公开(公告)号：EP0629609B1
公开(公告)日：1996-12-04
申请号：EP94111766.5
申请日：1990-05-16
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Hayase, Yoshio , Kataoka, Takahiro , Takenaka, Hideyuki , Ichinari, Mitsuhiro , Masuko, Michio , Takahashi, Toshio , Tanimoto, Norihiko
IPC分类号： C07C249/12 , C07C251/48 , C07D213/64 , C07D239/34 , C07D251/22 , A01N37/50
CPC分类号： C07C249/12 , A01N37/50 , C07C251/48 , C07C317/44 , C07C323/60 , C07D213/64 , C07D215/227 , C07D239/34 , C07D277/68 , C07D303/46 , C07D307/36 , C07D307/40 , C07D307/42 , C07D309/12 , C07F7/10

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